Dissociation of angiotensin il-stimulated activation of mitogen-activated protein kinase kinase from vascular contraction

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 3, 1998, Pages 1431-1438

  Watts, Stephanie W ^a   Florian, Jennifer A ^a   Monroe, Kimberly M ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; FLAVONOID; GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; NITRILE; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; TYRPHOSTIN; TYRPHOSTIN AG-490; 1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; DAIDZEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE; NIFEDIPINE; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE INHIBITOR; SEROTONIN; VANADATE SODIUM;

ANIMAL; AORTA; ARTICLE; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; IN VITRO STUDY; MALE; METABOLISM; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; CONTROLLED STUDY; ENZYME INHIBITION; FORCE TRANSDUCER; IMMUNOBLOTTING; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL;

ANGIOTENSIN II; ANIMALS; AORTA; ENZYME ACTIVATION; FLAVONOIDS; GENISTEIN; MALE; MAP KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUSCLE, SMOOTH, VASCULAR; NITRILES; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANGIOTENSIN; TYRPHOSTINS; VASOCONSTRICTION;

EID: 0032160078     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Alexander RW and Griendling KK (1996) Signal transduction in vascular smooth muscle. J Hypertens 14 (suppl 5):S51-S54.
2. Berk BC and Corson MA (1997) Angiotensin II signal transduction in vascular smooth muscle: role of tyrosine kinases. Circ Res 80: 607-616.
3. Bottari SP, King IN, Reichlin S, Dahlstroem I, Lydon N and deGasparo M (1992) The angiotensin AT2 receptor stimulates protein tyrosine phosphatase activity and mediates inhibition of particulate guanylate cyclase. Biochem Biophys Res Commun 183: 206-211.
4. DiSalvo J, Steusloff A, Semenchuk L, Satoh S, Kolquist K and Pfitzer G (1993) Tyrosine kinase inhibitors suppress agonist-induced contraction in smooth muscle. Biochem Biophys Res Commun 190: 968-974.
5. Dubey RK, Roy A and Overbeck HW ( 1992) Culture of renal arteriolar smooth muscle cells; mitogenic responses to angiotensin II. Circ Res 71: 1143-1152.
6. Dudley DT, Pang L, Decker SJ, Bridges AJ and Saltiel AR (1995) A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc NatlAcad Sei USA 92: 7686-7689.
7. Florian JA and Watts SW (1998) Integration of mitogen-activated protein kinase kinase activation in vascular 5-hydroxytryptamine2A receptor signal transduction. J Pharmacol Exp Ther 284: 346-355.
8. Force T, Kyriakis JM, Avruch J and Bonventre JV (1991) Endothelin, vasopressin and angiotensin II enhance tyrosine phosphorylation by protein kinase C-dependent and -independent pathways in glomerular mesangial cells. J Biol Chem 266: 6650-6656.
9. Griendling KK, Lassegue B and Alexander RS (1996) Angiotensin receptors and their therapuetic implications. Annu Rev Pharmacol Toxicol 36: 281-306.
10. Griendling KK, Ushio-Fukai M, Lassegue B and Alexander RW (1997) Angiotensin II signaling in vascular smooth muscle. Hypertension 29: 366-373.
11. Helin K, Stoll M, Meffert S, Stroth U and Unger T (1997) The role of angiotensin receptors in cardiovacular diseases. Ann Med 29: 23-29.
12. Hollenberg MD (1994) Tyrosine kinase pathways and the regulation of smooth muscle contractility. Trends Pharmacol Sei 15: 108-114.
13. Huwiler A, Stabel S, Fabbro D and Pfeilschifter J (1995) Platelet-derived growth factor and angiotensin II stimulate the mitogen activated protein kinase cascade in renal mesangial cells: comparison of hypertrophie and hyperplastic agonists. Biochem J 305: 777-784.
14. Kambayashi Y, Bardhan S and Inagami T (1993a) Peptide growth factors markedly decrease the ligand binding of angiotensin II type 2 receptor in rat cultured vascular smooth muscle cells. Biochem Biophsy Res Commun 194: 478-482.
15. Kambayashi Y, Bardhan S, Takahashi K, Tsuzuki S, Inui H, Hamakubo T and Inagami T (1993b) Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition. J Biol Chem 268: 24543-24546.
16. Laniyonu AA, Saifeddine M, Yang S-G and Hollenberg MD (1994) Tyrosine kinase inhibitors and the contractile action of G protein-linked vascular agonists. Can J Physiol Pharmacol 72: 1075-1085.
17. Lassegue B, Griendling KK, Alexander W (1994) In: Saavedra JM, Timmermans PBMWM, eds. Angiotensin II Receptors. New York, NY: Plenum Press; 17-48.
18. Leduc I, Hadda P, Giasson E and Meloche S (1995) Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cell. Mol Pharmacol 48: 582-592.
19. Molloy LG and Sauro MD (1996) Tyrosine kinase inhibition suppreses angiotensin contraction in hypertensive and normotensive small resistance arteries. Life Sei 58: PL317-PL324.
20. Mukoyama M, Nakajima M, Horiuchi M, Sasamura H, Pratt RE and Dzau VJ (1993) Expression cloning of type 2 angiotensin II receptor reveals a unique class: of seven-transmembrane receptors. J Biol Chem 268: 24539-24542.
21. Nakajima M, Hutchinson HG, Fujinaga M, Hayashida W, Morishita R, Zhang L, Horiuchi M, Pratt RE and Dzau VJ (1995) The angiotensin II type 2 (AT2) receptor antagonizes the growth effects of the ATI receptor: gain-function study using gene transfer. Proc Natl Acad Sei USA 92: 10663-10667.
22. Sabri A, Levy BI, Poitevin P, Caputo L, Faggin E, Marotte F, Rappaport L and Samuel JL (1997) Differential roles of ATI and AT2 receptor subtypes in vascular trophic and phenotypic changes in response to stimulation with angiotensin II. Arterioscler Thromb Vase Biol 17: 257-264.
23. Sambhi MP, Swaminathan N, Wang H and Rong H (1992) Increased EOF binding and EGFR mRNA expression in rat aorta with chronic administration of pressor angiotensin II. Biochem Med Met Biol 48: 8-18.
24. Sauro MD, Sudakow R and Burns S (1996) In vivo effects of angiotensin II on vascular smooth muscle contraction and blood pressure are mediated through a protein tyrosine kinase-dependent mechanism. J Pharmacol Exp Ther 277:1744-1750.
25. Servant MJ, Giasson E and Meloche S (1996) Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells. JBiol Chem 271: 16047-16052.
26. 2+D transients in vascular smooth muscle cells. Hypertension 27: 1097-1103.
27. Watts SW (1996) Serotonin activates the mitogen-activated protein kinase pathway in vascular smooth muscle: use of the mitogen-activated protein kinase kinase inhibitor PD098059. J Pharmacol Exp Ther 279: 1541-1550.
28. Watts SW, Yeum CH, Campbell G and Webb RC (1996) Serotonin stimulates protein tyrosyl-phosphorylation and vascular contraction via tyrosine kinase. J Vase fies 33: 288-298.
29. Wijetunge S, Aalkjaer C, Schachter M and Hughes AD (1992) Tyrosine kinase inhibitors block calcium channel currents in vascular smooth muscle cells. Biochem Biophys Res Commun 189: 1620-1623.
30. Yang S-G, Saifeddine M and Hollenberg MD (1992) Tyrosine kinase inhibitors and the contractile action of epidermal growth factor-urogastrone and other agonists in gastric smooth muscle. Can J Physiol Pharmacol 70: 85-93.
31. Yang S-G, Saifeddine M, Laniyonu A and Hollenberg MD (1993) Distinct signal transduction pathways for angiotensin II in guinea pig gastric smooth muscle: differential blockade by indomethacin and tyrosine kinase inhibitors. J Pharmacol ExpTAer264:958-966.