Expression and function of bradykinin B1 and B2 receptors in normal and inflamed rat urinary bladder urothelium

Journal of Physiology

Volumn 562, Issue 3, 2005, Pages 859-871

  Chopra, Bikramjit ^a   Barrick, Stacey R ^a   Meyers, Susan ^a   Beckel, Jonathan M ^a   Zeidel, Mark L ^a   Ford, Anthony P D W ^b   de Groat, William C ^a   Birder, Lori A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BRADYKININ; BRADYKININ B1 RECEPTOR; BRADYKININ B1 RECEPTOR AGONIST; BRADYKININ B2 RECEPTOR; BRADYKININ[1-8]; CALCIUM ION; CYCLOPHOSPHAMIDE; ICATIBANT; MESSENGER RNA; PURINE P2 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; PURINERGIC P2 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYSTITIS; CYSTOMETRY; DETRUSOR MUSCLE; EPITHELIUM CELL; FEMALE; IMMUNOREACTIVITY; MICTURITION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; RAT; RECEPTOR UPREGULATION; URINARY TRACT FUNCTION; UROTHELIUM; ADULT; BLADDER; CALCIUM CELL LEVEL; EC50; EVOKED RESPONSE; OVERACTIVE BLADDER; SMOOTH MUSCLE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CYCLOPHOSPHAMIDE; CYSTITIS; FEMALE; GENE EXPRESSION REGULATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, BRADYKININ B1; RECEPTOR, BRADYKININ B2; TISSUE DISTRIBUTION; URINARY BLADDER; UROTHELIUM;

EID: 13844280353     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2004.071159     Document Type: Article

References (57)

1. Ahluwalia A, Maggi CA, Santicioli P, Lecci A & Giuliani S (1994). Characterization of the capsaicin-sensitive component of cyclophosphamide-induced inflammation in the rat urinary bladder. Br J Pharmacol 111, 1017-1022.
2. Ahluwalia A & Perretti M (1999). B1 receptors as a new inflammatory target. Could this B the 1? Trends Pharmacol Sci 20 100-104.
3. Andersson KE, Hedlund H & Stahl M (1992). Contractions induced by angiotensin I, angiotensin II and bradykinin in isolated smooth muscle from the human detrusor. Acta Physiol Scand 145 253-259.
4. Andreeva L & Rang HP (1993). Effect of bradykinin and prostaglandins on the release of calcitonin gene-related peptide-like immunoreactivity from the rat spinal cord in vitro. Br J Pharmacol 108, 185-190.
5. Apodaca G, Kiss S, Ruiz W, Meyers S, Zeidel M & Birder L (2003). Disruption of bladder epithelium barrier function after spinal cord injury. Am J Physiol Renal Physiol 284, F966-F976.
6. Asano M, Hatori C, Inamura N, Sawai H, Hirosumi J, Fujiwara T & Nakahara K (1997). Effects of a nonpeptide bradykinin B2 receptor antagonist, FR167344, on different in vivo animal models of inflammation. Br J Pharmacol 122, 1436-1440.
7. Birder LA, Apodaca G, de Groat WC & Kanai AJ (1998). Adrenergic- and capsaicin-evoked nitric oxide release from urothelium and afferent nerves in urinary bladder. Am J Physiol 275, F226-F229.
8. Birder LA, Barrick SR, Roppolo JR, Kanai AJ, de Groat WC, Kiss S & Buffington CA (2003). Feline interstitial cystitis results in mechanical hypersensitivity and altered ATP release from bladder urothelium. Am J Physiol Renal Physiol 285, F423-F429.
9. Birder LA, Kanai AJ, de Groat WC, Kiss S, Nealen ML, Burke NE, Dineley KE, Watkins S, Reynolds IJ & Caterina MJ (2001). Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells. Proc Natl Acad Sci U S A 98, 13396-13401.
10. Birder LA, Nakamura Y, Kiss S, Nealen ML, Barrick S, Kanai AJ, Wang E, Ruiz G, De Groat WC, Apodaca G, Watkins S & Caterina MJ (2002a). Altered urinary bladder function in mice lacking the vanilloid receptor TRPV1. Nat Neurosci 5, 856-860.
11. Birder LA, Nealen ML, Kiss S, de Groat WC, Caterina MJ, Wang E, Apodaca G & Kanai AJ (2002b). Beta-adrenoceptor agonists stimulate endothelial nitric oxide synthase in rat urinary bladder urothelial cells. J Neurosci 22, 8063-8070.
12. Bouchelouche K & Nordling J (2003). Recent developments in the management of interstitial cystitis. Curr Opin Urol 13, 309-313.
13. Bouchelouche K, Kristensen B, Nordling J, Horn T & Bouchelouche P (2001). Increased urinary leukotriene E4 and eosinophil protein X excretion in patients with interstitial cystitis. J Urol 166, 2121-2125.
14. Calixto JB, Cabrini DA, Ferreira J & Campos MM (2000). Kinins in pain and inflammation. Pain 87, 1-5.
15. Cockayne DA, Hamilton SG, Zhu QM, Dunn PM, Zhong Y, Novakovic S, Malmberg AB, Cain G, Berson A, Kassotakis L, Hedley L, Lachnit WG, Burnstock G, McMahon SB & Ford AP (2000). Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice. Nature 407, 1011-1015.
16. Cox PJ (1979). Cyclophosphamide cystitis - identification of acrolein as the causative agent. Biochem Pharmacol 28, 2045-2049.
17. Dray A & Perkins M (1993). Bradykinin and inflammatory pain.Trends Neurosci 16, 99-104.
18. Elneil S, Skepper JN, Kidd EJ, Williamson JG & Ferguson DR (2001). Distribution of P2X(1) and P2X(3) receptors in the rat and human urinary bladder. Pharmacology 63, 120-128.
19. Erickson DR (2001). Urine markers of interstitial cystitis. Urology 57, 15-21.
20. Félétou M, Germain M, Thurieau C, Fauchere JL & Canat E (1994). Agonistic and antagonist properties of the bradykinin B2 receptor antagonist, HOE-140, in isolated blood vessels from different species. Br J Pharmacol 112, 683-689.
21. Ferguson DR (1999). Urothelial function. BJU Int 84 235-242.
22. Ferguson DR, Kennedy I & Burton TJ (1997). ATP is released from rabbit urinary bladder epithelial cells by hydrostatic pressure changes - a possible sensory mechanism? J Physiol 505, 503-511.
23. Habler HJ, Janig W & Koltzenburg M (1990). Activation of unmyelinated afferent fibres by mechanical stimuli and inflammation of the urinary bladder in the cat. J Physiol 425, 545-562.
24. Hock FJ, Wirth K, Albus U, Linz HJ, Gerhards G, Wiemer G, Henke ST, Breipohl G, Konig W, Knolle J & Scholkens BA (1991). HOE-140, a new potent and long acting bradykinin-antagonist: in vitro studies. Br J Pharmacol 102, 769-773.
25. Hu VY, Malley S, Dattilio A, Folsom JB, Zvara P & Vizzard MA (2003). COX-2 and prostanoid expression in micturition pathways after cyclophosphamide-induced cystitis in the rat. Am J Physiol Regul Integr Comp Physiol 284, R574-R585.
26. Hua XY & Yaksh TL (1993). Pharmacology of the effects of bradykinin, serotonin, and histamine on the release of calcitonin gene-related peptide from C-fiber terminals in the rat trachea. J Neurosci 13, 1947-1953.
27. Kajekar R & Myers AC (2000). Effect of bradykinin on membrane properties of guinea pig bronchial parasympathetic ganglion neurones. Am J Physiol Lung Cell Mol Physiol 278, L485-L491.
28. Keay SK & Warren JW (2002). Is interstitial cystitis an infectious disease? Int J Antimicrob Agents 19, 480-483.
29. Lavelle J, Meyers S, Ramage R, Bastacky S, Doty D, Apodaca G & Zeidel ML (2002). Bladder permeability barrier: recovery from selective injury of surface epithelial cells. Am J Physiol Renal Physiol 283, F242-F253.
30. Lavelle JP, Meyers SA, Ruiz WG, Buffington CA, Zeidel ML & Apodaca G (2000). Urothelial pathophysiological changes in feline interstitial cystitis: a human model. Am J Physiol Renal Physiol 278, F540-F553.
31. Lecci A, Giuliani S, Meini S & Maggi CA (1995). Pharmacological analysis of the local and reflex responses to bradykinin on rat urinary bladder motility in vivo. Br J Pharmacol 114, 708-714.
32. Lecci A, Meini S, Patacchini R, Tramontana M, Giuliani S, Criscuoli M & Maggi CA (1999). Effect of dexamethasone on cyclophosphamide-induced cystitis in rats: lack of relation with bradykinin B1 receptor-mediated motor responses. Eur J Pharmacol 369, 99-106.
33. Levy D & Zochodne D (2000). Increased mRNA expression of B1 and B2 bradykinin receptors and antinociceptive effects of their antagonists in an animal model of neuropathic pain. Pain 86, 265-271.
34. Maggi CA (1992). Prostanoids as local modulators of reflex micturition. Pharmacol Res 25, 13-20.
35. Maggi CA, Santicioli P, Del Bianco E, Lecci A & Guliani S (1993). Evidence for the involvement of bradykinin in chemically-evoked cystitis in anaesthetized rats. Naunyn Schmiedebergs Arch Pharmacol 347, 432-437.
36. Marceau F, Barabe J, St-Pierre S & Regoli D (1980). Kinin receptors in experimental inflammation. Can J Physiol Pharmacol 58, 536-542.
37. Meini S, Lecci A, Cucchi P, Catalioto RM, Criscuoli M & Maggi CA (1998). Inflammation modifies the role of cyclooxygenases in the contractile responses of the rat detrusor smooth muscle to kinin agonists. J Pharmacol Exp Ther 287, 137-143.
38. Meini S, Patacchini R, Giuliani S, Lazzeri M, Turini D, Maggi CA & Lecci A (2000). Characterization of bradykinin B(2) receptor antagonists in human and rat urinary bladder. Eur J Pharmacol 388, 177-182.
39. Parsons CL (1994). The therapeutic role of sulfated polysaccharides in the urinary bladder. Urol Clin North Am 21 93-100.
40. Parsons CL, Bautista SL, Stein PC & Zupkas P (2000). Cyto-injury factors in urine: a possible mechanism for the development of interstitial cystitis. J Urol 164, 1381-1384.
41. Parsons CL, Greenberger M, Gabal L, Bidair M & Barme G (1998). The role of urinary potassium in the pathogenesis and diagnosis of interstitial cystitis. J Urol 159, 1862-1866.
42. Poole S, Lorenzetti BB, Cunha JM, Cunha FQ & Ferreira SH (1999). Bradykinin B1 and B2 receptors, tumour necrosis factor alpha and inflammatory hyperalgesia. Br J Pharmacol 126, 649-656.
43. Ribeiro RA, Freitas HC, Campos MC, Santos CC, Figueiredo FC, Brito GA & Cunha FQ (2002). Tumor necrosis factor-alpha and interleukin-1beta mediate the production of nitric oxide involved in the pathogenesis of ifosfamide induced hemorrhagic cystitis in mice. J Urol 167, 2229-2234.
44. Rosamilia A, Clements JA, Dwyer PL, Kende M & Campbell DJ (1999). Activation of the kallikrein kinin system in interstitial cystitis. J Urol 162, 129-134.
45. Ruggieri MR, Wang J, Whitmore KE, Pontari MA & Hanno PM (1997). Expression of bradykinin 1 receptor subtype in interstitial cystitis bladder biopsies. J Urol 157, 131-136.
46. Schuligoi R, Peskar BA, Donnerer J & Amann R (1998). Bradykinin-evoked sensitization of neuropeptide release from afferent neurons in the guinea-pig lung. Br J Pharmacol 125, 388-392.
47. Sun Y & Chai TC (2004). Upregulation of P2X3 receptors during stretch of bladder urothelial cells from patients with interstitial oystitis. J Urol 171, 448-452.
48. Theoharides TC, Kempuraj D & Sant GR (2001). Mast cell involvement in interstitial cystitis: a review of human and experimental evidence. Urology 57, 47-55.
49. Trevisani M, Schmidlin F, Tognetto M, Nijkamp FP, Gies JP, Frossard N, Amadesi S, Folkerts G & Geppetti P (1999). Evidence for in vitro expression of B1 receptor in mouse trachea and urinary bladder. Br J Pharmacol 126, 1293-1300.
50. Truschel ST, Ruiz WG, Shulman T, Pilewski J, Sun TT, Zeidel ML & Apodaca G (1999). Primary uroepithelial cultures. A model system to analyze umbrella cell barrier function. J Biol Chem 274, 15020-15029.
51. Vizzard MA (2000a). Alterations in spinal cord Fos protein expression induced by bladder stimulation following cystitis. Am J Physiol Regul Integr Comp Physiol 278, R1027-R1039.
52. Vizzard MA (2000b). Changes in urinary bladder neurotrophic factor mRNA and NGF protein following urinary bladder dysfunction. Exp Neurol 161, 273-284.
53. Vizzard MA, Erdman SL & de Groat WC (1996). Increased expression of neuronal nitric oxide synthase in bladder afferent pathways following chronic bladder irritation. J Comp Neurol 370, 191-202.
54. Vlaskovska M, Kasakov L, Rong W, Bodin P, Bardini M, Cockayne DA, Ford AP & Burnstock G (2001). P2X3 knock-out mice reveal a major sensory role for urothelially released ATP. J Neurosci 21, 5670-5677.
55. Wein AJ & Hanno PM (2002). Targets for therapy of the painful bladder. Urology 59, 68-73.
56. Wirth K, Hock FJ, Albus U, Linz W, Alpermann HG, Anagnostopoulous H, Henke ST, Breipohl G, Konig W, Knolle J & Scholkens BA (1991). HOE-140, a new potent and long acting bradykinin antagonist: in vivo studies. Br J Pharmacol 102, 774-777.
57. Yoshimura N & de Groat WC (1999). Increased excitability of afferent neurons innervating rat urinary bladder after chronic bladder inflammation. J Neurosci 19, 4644-4653.