Effects of Protein Tyrosine Kinase Inhibitors on Contractility of Isolated Bronchioles of the Rat

American Journal of Respiratory Cell and Molecular Biology

Volumn 16, Issue 4, 1997, Pages 372-378

  Chopra, Lorna C ^a   Hucks, David ^a   Twort, Charles H C ^a   Ward, Jeremy P T ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; ACETYLCHOLINE; ALPHA CYANO 3 ETHOXY 4 HYDROXY 5 (PHENYLTHIOMETHYL)CINNAMAMIDE; ALPHA CYANOTHIOCAFFEIC ACID AMIDE; CAFFEIC ACID DERIVATIVE; CARBACHOL; CINNAMIC ACID DERIVATIVE; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR; GENISTEIN; INDOLE DERIVATIVE; IONOMYCIN; ISOFLAVONE DERIVATIVE; PROTEIN TYROSINE KINASE; RO 31-8220; SEROTONIN; SULFIDE; TYRPHOSTIN;

ANIMAL; ARTICLE; BRONCHUS; DRUG ANTAGONISM; DRUG EFFECT; IN VITRO STUDY; MALE; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; RAT; SMOOTH MUSCLE; WISTAR RAT;

ACETYLCHOLINE; ANIMALS; BRONCHI; CAFFEIC ACIDS; CARBACHOL; CINNAMATES; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; GENISTEIN; INDOLES; IONOMYCIN; ISOFLAVONES; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PROTEIN-TYROSINE KINASES; RATS; RATS, WISTAR; SEROTONIN; SULFIDES; TYRPHOSTINS;

EID: 0031110583     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.16.4.9115747     Document Type: Article

References (30)

1. Schramm, C. M., and M. M. Grunstein. 1992. Assessment of signal transduction mechanisms regulating airway smooth muscle contractility. Am. J. Physiol. 262:L119-L139.
2. Glenney, J. R. 1991. Tyrosine-phosphorylated proteins: mediators of signal transduction from the tyrosine kinases. Biochim. Biophys. Acta 1134: 113-127.
3. 2+ sensitivity. Can. J. Physiol. Pharmacol. 72:1434-1439.
4. Hollenberg, M. D. 1994. Tyrosine kinase pathways and the regulation of smooth muscle contractility [Review]. Trends. Pharmacol. Sci. 15:108-114.
5. Di Salvo, J., A. Steusloff, L. Semenchuk, S. Satoh, K. Kolquist, and G. Pfitzer. 1993. Tyrosine kinase inhibitors suppress agonist-induced contraction in smooth muscle. Biochem. Biophys. Res. Commun. 190:968-974.
6. Steusloff, A., E. Paul, L. A. Semenchuk, J. Di Salvo, and G. Pfitzer. 1995. Modulation of Ca2+ sensitivity in smooth muscle by genistein and protein tyrosine phosphorylation. Arch. Biochem. Biophys. 320:236-242.
7. Toma, C., P. E. Jensen, D. Prieto, A. Hughes, M. J. Mulvaney, and C. Aalkjaer. 1995. Effects of tyrosine kinase inhibitors on the contractility of rat mesenteric resistance arteries. Br. J. Pharmacol. 114:1266-1272.
8. Abebe, W., and D. K. Agrawal. 1995. Role of tyrosine kinases in norepinephrine-induced contraction of vascular smooth muscle. J. Cardiovosc. Pharmacol. 26:153-159.
9. Filipeanu, C. M., E. Brailoiu, G. Huhurez, S. Slatineanu, O. Baltatu, and D. D. Branisteanu. 1995. Multiple effects of tyrosine kinase inhibitors on vascular smooth muscle contraction. Eur. J. Pharmacol. 281:29-35.
10. Tsuda, T., Y. Kawahara, K. Shii, M. Koide, Y. Ishida, and M. Yokohama. 1991. Vasoconstrictor induced protein-tyrosine phosphorylation in cultured vascular smooth muscle cells. FEBS Lett. 258:44-48.
11. Semenchuk, L. A., and J. Di Salvo. 1995. Receptor-activated increases in intracellular calcium and protein tyrosine phosphorylation in vascular smooth muscle cells. FEBS Lett. 370:127-130.
12. Laniyonu, A., M. Saifeddine, S. G. Yang, and M. D. Hollenberg. 1994. Tyrosine kinase inhibitors and the contractile action of G-protein-linked vascular agonists. Can. J. Physiol. Pharmacol. 72:1075-1085.
13. Jinsi, A., and R. C. Deth. 1995. Alpha 2-adrenoceptor-mediated vasoconstriction requires a tyrosine kinase. Eur. J. Pharmacol. 277:29-34.
14. Lee, K. M., K. Toscas, and M. L. Villereal. 1993. Inhibition of bradykinin- and thapsigargin-induced Ca2+ entry by tyrosine kinase inhibitors. J. Biol. Chem. 268:9945-9948.
15. Wijetunge, S., C. Aalkjaer, M. Schachter, and A. D. Hughes. 1992. Tyrosine kinase inhibitors block calcium channel currents in vascular smooth muscle cells. Biochem. Biophys. Res. Com. 189:1620-1623.
16. Kusaka, M., and N. Sperelakis. 1995. Inhibition of L-type calcium current by genistein, a tyrosine kinase inhibitor, in pregnant rat myometrial cells. Biochim. Biophys. Acta 1240:196-200.
17. Shiraishi, T., T. Domoto, N. Imai, Y. Shimada, and K. Watanabe. 1987. Specific inhibitors of tyrosine specific protein kinase, synthetic 4-hydroxycinnamide derivatives. Biochem. Biophys. Res. Commun. 147:322-328.
18. Shiraishi, T., M. K. Owado, M. Tatsuka, T. Yamashita, K. Watanabe, and T. Kakunaga. 1989. Specific inhibitors of tyrosine specific protein kinases: properties of 4-hydroxycinnamide derivatives in vitro. Cancer Res. 49:2374-2378.
19. Teshima, R., H. Ikebuchi, J. Sawada, T. Furuno, M. Nakanishi, and T. Terao. 1994. Effects of herbimycin A and ST638 on Fc epsilon receptor-mediated histamine release and Ca2+ signals in rat basophilic leukemia (RBL-2H3) cells Biochim. Biophys. Acta 1221:37-46.
20. Martinson, E. A., S. Scheible, and P. Presek. 1994. Inhibition of phospholipase D of human platelets by protein tyrosine kinase inhibitors. Cell Mol. Biol. (Noisy-Le-Grand) 40:627-634.
21. Hirst, S. J., B. L. J. Webb, M. A. Giembycz, P. J. Barnes, and C. H. Twort. 1995. Inhibition of fetal calf serum-stimulated proliferation of rabbit cultured tracheal smooth muscle cells by selective inhibitors of protein kinase C and protein tyrosine kinase. Am. J. Respir. Cell Mol. Biol. 12: 149-161.
22. Chopra, L. C., C. H. Twort, and J. P. T. Ward. 1994. Differences in sensitivity to the specific protein kinase C inhibitor RO31-8220 between small and large bronchioles of the rat. Br. J. Pharmacol. 113:1237-1242.
23. Davis, P. D., C. H. Hill, E. Keech, G. Lawton, J. S. Nixon, A. D. Sedgwick, J. Wadsworth, D. Westmacott, and S. E. Wilkinson. 1989. Potent selective inhibitors of protein kinase C. FEBS Lett. 259:61-63.
24. Tolloczko, B., Y. L. Jia, and J. G. Martin. 1995. Serotonin-evoked calcium transients in airway smooth muscle cell. Am. J. Physiol. 269:L234-L240.
25. Inoue, R., Y. Waniishi, K. Yamada, and Y. Ito. 1994. A possible role of tyrosine kinases in the regulation of muscarinic receptor-activated cation channels in guinea pig ileum. Biochem. Biophys. Res. Commun. 203: 1392-1397.
26. Baron, C. B., J. Pompeo, D. Blackman, and R. F. Coburn. 1993. Common phosphatidyl-inostitol 4,5-biphosphate pools are involved in carbachol and serotonin activation of tracheal smooth muscle. J. Pharmacol. Exp. Therap. 266:8-15.
27. Keung, W. M. 1993. Biochemical studies of a new class of alcohol dehydrogenase inhibitors from Radix puerariae. Alcoholism 17:1254-1260.
28. Huang, J., M. Nasr, Y. Kim, and H. R. Matthews. 1992. Genistein inhibits protein histidine kinase. J. Biol. Chem. 267:15511-15515.
29. Higashi, K., and H. Ogawara. 1994. Daidzein inhibits insulin- or insulin-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells. Biochim. Biophys. Acta 1221:29-35.
30. Young, S. W., R. C. Poole, A. T. Hudson, A. P. Halestrap, R. M. Denton, and J. M. Tavare. 1993. Effects of tyrosine kinase inhibitors on protein kinase-independent systems. FEBS Lett. 316:278-282.