Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles

British Journal of Pharmacology

Volumn 132, Issue 1, 2001, Pages 127-134

  Janssen, L J ^a   Premji, M ^a   Netherton, S ^a   Coruzzi, J ^a   Lu Chao, H ^a   Cox, P G ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Contraction; Isoprostanes; MAP kinase; Prostanoid receptors; Pulmonary artery; Pulmonary vein; Relaxation; Tyrosine kinase; Vascular smooth muscle

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 6 [2 (2 CHLOROPHENYL) 4 (2 HYDROXYPHENYL) 1,3 DIOXAN 5 YL] 4 HEXENOIC ACID; 6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; 8 ISOPROSTAGLANDIN E1; 8 ISOPROSTAGLANDIN E2; 8 ISOPROSTAGLANDIN F2 ALPHA; 8 ISOPROSTAGLANDIN F2 BETA; CALCIUM ION; CALPHOSTIN C; CHELERYTHRINE; FASUDIL; GENISTEIN; ISOPROSTANE; PROTEIN TYROSINE KINASE; RHO KINASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; DOSE RESPONSE; HUMAN; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY VEIN; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ANIMALS; CALCIUM; DOGS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; PHOSPHOTRANSFERASES; PROSTAGLANDIN ANTAGONISTS; PROSTAGLANDINS E, SYNTHETIC; PROSTAGLANDINS F, SYNTHETIC; PROSTAGLANDINS, SYNTHETIC; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PULMONARY CIRCULATION; SIGNAL TRANSDUCTION; VASOCONSTRICTOR AGENTS;

EID: 0035141402     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703784     Document Type: Article

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