Increased basal phosphorylation of detrusor smooth muscle myosin in alloxan-induced diabetic rabbit is mediated by upregulation of Rho-kinase β and CPI-17

American Journal of Physiology - Renal Physiology

Volumn 290, Issue 3, 2006, Pages

  Chang, Shaohua ^a   Hypolite, Joseph A ^a   DiSanto, Michael E ^a,b   Changolkar, Arun ^a   Wein, Alan J ^a   Chacko, Samuel ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Calcium sensitization; Hyperglycemia; Urinary bladder dysfunction

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ALLOXAN; BETHANECHOL; CALCIUM; DRINKING WATER; GLUCOSE; MYOSIN; RHO KINASE INHIBITOR; SUCROSE; AMIDE; CPI 17 PROTEIN, ORYCTOLAGUS CUNICULUS; CPI-17 PROTEIN, ORYCTOLAGUS CUNICULUS; DIURETIC AGENT; ENZYME INHIBITOR; MUSCLE PROTEIN; PHOSPHOPROTEIN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN SERINE THREONINE KINASE; PYRIDINE DERIVATIVE; RHO KINASE; RHO-ASSOCIATED KINASE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER WALL; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DIURESIS; DRUG INHIBITION; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; MUSCLE RELAXATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIZATION; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION; WESTERN BLOTTING; ANIMAL; BLADDER; BLOOD; DIABETIC NEPHROPATHY; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; SMOOTH MUSCLE;

AMIDES; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DIURESIS; DIURETICS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUSCLE PROTEINS; MUSCLE, SMOOTH; MYOSINS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; RABBITS; URINARY BLADDER;

EID: 33645579950     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00235.2005     Document Type: Article

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