WSX-1: A key role in induction of chronic intestinal nematode infection

Journal of Immunology

Volumn 172, Issue 12, 2004, Pages 7635-7641

  Bancroft, Allison J ^a   Humphreys, Neil E ^a   Worthington, John J ^a   Yoshida, Hiroki ^b,c   Grencis, Richard K ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b SAGA UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; COMPLEMENTARY DNA; CYTOKINE; CYTOKINE RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 27; INTERLEUKIN RECEPTOR; RECEPTOR SUBTYPE; RECOMBINANT INTERLEUKIN 12; TOLL LIKE RECEPTOR; TYPE I CYTOKINE RECEPTOR; UNCLASSIFIED DRUG; WSX 1 CYTOKINE RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CHRONIC DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSCRIPTION; IMMUNE RESPONSE; INFECTION RESISTANCE; MOUSE; NEMATODE; NEMATODIASIS; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TH1 CELL; TRICHURIASIS; TRICHURIS; TRICHURIS MURIS;

EID: 2942564059     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.12.7635     Document Type: Article

References (30)

1. + T cells. Immunity 16:779.
2. Sprecher, C. A., F. J. Grant, J. W. Baumgartner, S. R. Presnell, S. K. Schrader, T. Yamagiwa, T. E. Whitmore, P. J. O'Hara, and D. F. Foster. 1998. Cloning and characterization of a novel class I cytokine receptor. Biochem. Biophys. Res. Commun. 256:82.
3. Chen, Q., N. Ghilardi, H. Wang, T. Baker, M.-H. Xie, A. Gurney, I. S. Grewal, and F. J. de Sauvage. 2000. Development of Th-1 type immune responses requires the type 1 cytokine receptor TCCR. Nature 407:916.
4. Yoshida, H., S. Hamano, G. Senaldi, T. Covey, R. Faggioni, S. Mu, M. Xia, A. C. Wakeham, H. Nishina, J. Potter, et al. 2001. WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection. Immunity 15:569.
5. Takeda A., S. Hamano, A. Yamanaka, T. Hanada, T. Ishibashi, T. W. Mak, A. Yoshimura, and H. Yoshida. 2003. Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J. Immunol. 170:4886.
6. Szabo, S. J., S. T. Kim, G. L. Costa, X. Zhang, C. G. Fathman, and L. H. Glimcher. 2000. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100:655.
7. Weigmann, B., and M. F. Neurath. 2002. T-bet and mucosal responses in the gastro-intestinal tract. Gut 51:301.
8. Villarino, A., L. Hibbert, L. Lieberman, E. Wilson, T. Mak, H. Yoshida, R. Kastelein, C. Saris, and C. A. Hunter. 2003. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 19:645.
9. Hamano, S., K. Himeno, Y. Miyazaki, K. Ishii, A. Yamanaka, A. Takeda, M. Zhang, H. Hisaeada, T. W. Mak, A. Yoshimura, and H. Yoshida. 2003. WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production. Immunity 19:657.
10. Else, K. J., and R. K. Grencis. 1991. Cellular immune responses to the murine nematode parasite Trichuris muris. I. Differential cytokine production during acute or chronic infection. Immunology 72:508.
11. Else, K. J., L. Hültner, and R. K. Grencis. 1992. Cellular immune responses to the murine nematode parasite Trichuris muris. II. Differential induction of TH-cell subsets in resistant versus susceptible mice. Immunology 75:232.
12. Bancroft, A. J., A. N. McKenzie, and R. K. Grencis. 1998. A critical role for IL-13 in resistance to intestinal nematode infection. J. Immunol. 160:3453.
13. Else, K. J., F. D. Finkelman, C. R. Maliszewski, and R. K. Grencis. 1994. Cytokine-mediated regulation of chronic intestinal helminth infection. J. Exp. Med. 179:347.
14. Bancroft, A. J., K. J. Else, J. P. Sypek, and R. K. Grencis. 1997. Interleukin-12 promotes a chronic intestinal nematode infection. Eur. J. Immunol. 27:866.
15. Helmby, H., K. Takeda, S. Akira, and R. K. Grencis. 2001. Interleukin (IL)-18 promotes the development of chronic gastrointestinal helminth infection by downregulating IL-13. J. Exp. Med. 194:355.
16. Bancroft, A. J., K. J. Else, N. E. Humphreys, and R. K. Grencis. 2001. The effect of challenge and trickle Trichuris muris infections on the polarisation of the immune response. Int. J. Parasitol. 31:1627.
17. Gajewski, T. F., and F. W. Fitch. 1988. Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J. Immunol. 140:4245.
18. Alexander, W. S., R. Starr, J. E. Fenner, C. L. Scott, E. Handman, N. S. Sprigg, J. E. Corbin, A. L. Cornish, R. Darwiche, C. M. Owczarek, et al. 1999. SOCS1 is a critical inhibitor of IFN-γ signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell 98:597.
19. Gourley, T., S. Roys, N. W. Lukacs, S. L. Kunkel, R. A. Flavell, and C.-H. Chang. 1999. A novel role for the major histocompatibility complex class II transactivator CIITA in the repression of IL-4 production. Immunity 10:377.
20. Zhou, M., W. Ouyang, Q. Gong, S. G. Katz, J. M. White, S. H. Orkin, and K. M. Murphy. 2001. Friend of GATA-1 represses GATA-3-dependent activity in CD4 T cells. J. Exp. Med. 194:1461.
21. Wakelin, D. 1967. Acquired immunity to Tichuris muris in the albino laboratory mouse. Parasitology 57:515.
22. Else, K. J., G. M. Entwistle, and R. K. Grencis. 1993. Correlations between worm burden and markers of Th1 and Th2 cell subset induction in an inbred strain of mouse infected with Trichuris muris. Parasite Immunol. 15:595.
23. Bancroft, A. J., K. J. Else, and R. K. Grencis. 1994. Low-level infection with Trichuris muris significantly affects the polarization of the CD4 response. Eur. J. Immunol. 24:3113.
24. Finkelman, F. D., J. Holmes, I. M. Katona, J. F. Urban, Jr., M. P. Beckman, L. S. Parks, K. A. Schooley, R. L. Coffman, T. R. Mosmann, and W. E. Paul. 1990. Lymphokine secretion of in vivo immunoglobulin isotype selection. Annu. Rev. Immunol. 8:303.
25. Koyama, K. 2002. NK1.1 cell depletion in vivo fails to prevent protection against infection with the murine nematode Trichuris muris. Parasite Immunol. 24:527.
26. Else, K. J., and R. K. Grencis. 1996. Antibody-independent effector mechanisms in resistance to the intestinal nematode parasite Trichuris muris. Infect. Immun. 64:2950.
27. Bancroft, A. J., D. Artis, D. D. Donaldson, J. P. Sypek, and R. K. Grencis. 2000. Gastrointestinal nematode expulsion in IL-4 knockout mice is IL-13 dependent. Eur. J. Immunol. 30:2083.
28. + T cells through Stat1-dependent and -independent mechanisms. Proc. Natl. Acad. Sci. USA 100:15047.
29. Komine, O., K. Hayashi, W. Natsume, T. Watanabe, Y. Seki, N. Seki, R. Yagi, W. Sukzuki, H. Tamauchi, K. Hozumi, et al. 2002. The Runx1 transcription factor inhibits the differentiation of naïve CD4 T cells into the Th2 lineage by repressing GATA3 expression. J. Exp. Med. 198:51.
30. Helmby, H., and R. K. Grencis. 2003. Essential role for TLR4 and MyD88 in the development of chronic intestinal nematode infection. Eur. J. Immunol. 33:2974.