-
1
-
-
33846604242
-
How common are the "common" neurologic disorders?
-
Hirtz, D.; Thurman, D. J.; Gwinn-Hardy, K.; Mohamed, M.; Chaudhuri, A. R.; Zalutsky, R. How common are the "common" neurologic disorders? Neurology 2007, 68, 326-337.
-
(2007)
Neurology
, vol.68
, pp. 326-337
-
-
Hirtz, D.1
Thurman, D.J.2
Gwinn-Hardy, K.3
Mohamed, M.4
Chaudhuri, A.R.5
Zalutsky, R.6
-
2
-
-
0035003439
-
Chemistry and biochemistry of oxidative stress in neurodegenerative disease
-
Sayre, L. M.; Smith, M. A.; Perry, G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr. Med. Chem. 2001, 8, 721-738.
-
(2001)
Curr. Med. Chem
, vol.8
, pp. 721-738
-
-
Sayre, L.M.1
Smith, M.A.2
Perry, G.3
-
3
-
-
0037237927
-
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
-
Ischiropoulos, H.; Beckman, J. S. Oxidative stress and nitration in neurodegeneration: cause, effect, or association? J. Clin. Invest. 2003, 111, 163-169.
-
(2003)
J. Clin. Invest
, vol.111
, pp. 163-169
-
-
Ischiropoulos, H.1
Beckman, J.S.2
-
4
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
discussion S36-28
-
Jenner, P. Oxidative stress in Parkinson's disease. Ann. Neurol. 2003, 53 Suppl 3, S26-36; discussion S36-28.
-
(2003)
Ann. Neurol
, vol.53
, Issue.SUPPL. 3
-
-
Jenner, P.1
-
5
-
-
3142514196
-
Oxidative stress in neurodegeneration: Cause or consequence?
-
Andersen, J. K. Oxidative stress in neurodegeneration: cause or consequence? Nat. Med. 2004, 10 Suppl, S18-25.
-
(2004)
Nat. Med
, vol.10
, Issue.SUPPL.
-
-
Andersen, J.K.1
-
6
-
-
1642308134
-
Neurodegenerative diseases and oxidative stress
-
Barnham, K. J.; Masters, C. L.; Bush, A. I. Neurodegenerative diseases and oxidative stress. Nat Rev Drug Discov 2004, 3, 205-214.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 205-214
-
-
Barnham, K.J.1
Masters, C.L.2
Bush, A.I.3
-
7
-
-
33751003518
-
Oxidative stress in ALS: A mechanism of neurodegeneration and a therapeutic target
-
Barber, S. C.; Mead, R. J.; Shaw, P. J. Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target. Biochim. Biophys. Acta 2006, 1762, 1051-1067.
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 1051-1067
-
-
Barber, S.C.1
Mead, R.J.2
Shaw, P.J.3
-
8
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin, M. T.; Beal, M. F. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006, 443, 787-795.
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
9
-
-
33747861696
-
Involvement of oxidative stress in Alzheimer disease
-
Nunomura, A.; Castellani, R. J.; Zhu, X.; Moreira, P. I.; Perry, G.; Smith, M. A. Involvement of oxidative stress in Alzheimer disease. J. Neuropathol. Exp. Neurol. 2006, 65, 631-641.
-
(2006)
J. Neuropathol. Exp. Neurol
, vol.65
, pp. 631-641
-
-
Nunomura, A.1
Castellani, R.J.2
Zhu, X.3
Moreira, P.I.4
Perry, G.5
Smith, M.A.6
-
10
-
-
0033559462
-
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
-
Nunomura, A.; Perry, G.; Pappolla, M. A.; Wade, R.; Hirai, K.; Chiba, S.; Smith, M. A. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J. Neurosci. 1999, 19, 1959-1964.
-
(1999)
J. Neurosci
, vol.19
, pp. 1959-1964
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Wade, R.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
11
-
-
33749525194
-
RNA damage and surveillance under oxidative stress
-
Li, Z.; Wu, J.; Deleo, C. J. RNA damage and surveillance under oxidative stress. IUBMB life 2006, 58, 581-588.
-
(2006)
IUBMB life
, vol.58
, pp. 581-588
-
-
Li, Z.1
Wu, J.2
Deleo, C.J.3
-
12
-
-
24044475562
-
Hypothetical role of RNA damage avoidance in preventing human disease
-
Bregeon, D.; Sarasin, A. Hypothetical role of RNA damage avoidance in preventing human disease. Mutat. Res. 2005, 577, 293-302.
-
(2005)
Mutat. Res
, vol.577
, pp. 293-302
-
-
Bregeon, D.1
Sarasin, A.2
-
13
-
-
41149166082
-
Nucleic acid oxidation in Alzheimer disease
-
Moreira, P. I.; Nunomura, A.; Nakamura, M.; Takeda, A.; Shenk, J. C.; Aliev, G.; Smith, M. A.; Perry, G. Nucleic acid oxidation in Alzheimer disease. Free Radic. Biol. Med. 2008, 44, 1493-1505.
-
(2008)
Free Radic. Biol. Med
, vol.44
, pp. 1493-1505
-
-
Moreira, P.I.1
Nunomura, A.2
Nakamura, M.3
Takeda, A.4
Shenk, J.C.5
Aliev, G.6
Smith, M.A.7
Perry, G.8
-
14
-
-
30644474179
-
A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: Greater RNA than DNA oxidation in rat liver after doxorubicin administration
-
Hofer, T.; Seo, A. Y.; Prudencio, M.; Leeuwenburgh, C. A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration. Biol. Chem. 2006, 387, 103-111.
-
(2006)
Biol. Chem
, vol.387
, pp. 103-111
-
-
Hofer, T.1
Seo, A.Y.2
Prudencio, M.3
Leeuwenburgh, C.4
-
15
-
-
0034625125
-
Activated leukocytes oxidatively damage DNA, RNA, and the nucleotide pool through halide-dependent formation of hydroxyl radical
-
Shen, Z.; Wu, W.; Hazen, S. L. Activated leukocytes oxidatively damage DNA, RNA, and the nucleotide pool through halide-dependent formation of hydroxyl radical. Biochemistry (Mosc). 2000, 39, 5474-5482.
-
(2000)
Biochemistry (Mosc)
, vol.39
, pp. 5474-5482
-
-
Shen, Z.1
Wu, W.2
Hazen, S.L.3
-
16
-
-
15644362313
-
In vitro photooxidation of nucleic acids by ultraviolet A radiation
-
Wamer, W. G.; Wei, R. R. In vitro photooxidation of nucleic acids by ultraviolet A radiation. Photochem. Photobiol. 1997, 65, 560-563.
-
(1997)
Photochem. Photobiol
, vol.65
, pp. 560-563
-
-
Wamer, W.G.1
Wei, R.R.2
-
17
-
-
25144486774
-
Hydrogen peroxide causes greater oxidation in cellular RNA than in DNA
-
Hofer, T.; Badouard, C.; Bajak, E.; Ravanat, J. L.; Mattsson, A.; Cotgreave, I. A. Hydrogen peroxide causes greater oxidation in cellular RNA than in DNA. Biol. Chem. 2005, 386, 333-337.
-
(2005)
Biol. Chem
, vol.386
, pp. 333-337
-
-
Hofer, T.1
Badouard, C.2
Bajak, E.3
Ravanat, J.L.4
Mattsson, A.5
Cotgreave, I.A.6
-
18
-
-
0024455022
-
Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane
-
Fiala, E. S.; Conaway, C. C.; Mathis, J. E. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res. 1989, 49, 5518-5522.
-
(1989)
Cancer Res
, vol.49
, pp. 5518-5522
-
-
Fiala, E.S.1
Conaway, C.C.2
Mathis, J.E.3
-
19
-
-
0037082154
-
Quantification of 8-oxo-guanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectrometry
-
Weimann, A.; Belling, D.; Poulsen, H. E. Quantification of 8-oxo-guanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectrometry. Nucleic Acids Res 2002, 30, E7.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Weimann, A.1
Belling, D.2
Poulsen, H.E.3
-
20
-
-
24944565971
-
A new frontier for molecular medicine: Noncoding RNAs
-
Szymanski, M.; Barciszewska, M. Z.; Erdmann, V. A.; Barciszewski, J. A new frontier for molecular medicine: noncoding RNAs. Biochim. Biophys. Acta 2005, 1756, 65-75.
-
(2005)
Biochim. Biophys. Acta
, vol.1756
, pp. 65-75
-
-
Szymanski, M.1
Barciszewska, M.Z.2
Erdmann, V.A.3
Barciszewski, J.4
-
21
-
-
24744440117
-
Non-coding RNAs: New players in eukaryotic biology
-
Costa, F. F. Non-coding RNAs: new players in eukaryotic biology. Gene 2005, 357, 83-94.
-
(2005)
Gene
, vol.357
, pp. 83-94
-
-
Costa, F.F.1
-
22
-
-
33745602880
-
Noncoding RNAs in the mammalian central nervous system
-
Cao, X.; Yeo, G.; Muotri, A. R.; Kuwabara, T.; Gage, F. H. Noncoding RNAs in the mammalian central nervous system. Annu. Rev. Neurosci. 2006, 29, 77-103.
-
(2006)
Annu. Rev. Neurosci
, vol.29
, pp. 77-103
-
-
Cao, X.1
Yeo, G.2
Muotri, A.R.3
Kuwabara, T.4
Gage, F.H.5
-
23
-
-
33747706117
-
Non-coding RNAs in the nervous system
-
Mehler, M. F.; Mattick, J. S. Non-coding RNAs in the nervous system. J. Physiol. 2006, 575, 333-341.
-
(2006)
J. Physiol
, vol.575
, pp. 333-341
-
-
Mehler, M.F.1
Mattick, J.S.2
-
24
-
-
33847698971
-
The relationship between non-protein-coding DNA and eukaryotic complexity
-
Taft, R. J.; Pheasant, M.; Mattick, J. S. The relationship between non-protein-coding DNA and eukaryotic complexity. Bioessays 2007, 29, 288-299.
-
(2007)
Bioessays
, vol.29
, pp. 288-299
-
-
Taft, R.J.1
Pheasant, M.2
Mattick, J.S.3
-
25
-
-
12344274135
-
Expanding the 'central dogma': The regulatory role of nonprotein coding genes and implications for the genetic liability to schizophrenia
-
Perkins, D. O.; Jeffries, C.; Sullivan, P. Expanding the 'central dogma': the regulatory role of nonprotein coding genes and implications for the genetic liability to schizophrenia. Mol. Psychiatry 2005, 10, 69-78.
-
(2005)
Mol. Psychiatry
, vol.10
, pp. 69-78
-
-
Perkins, D.O.1
Jeffries, C.2
Sullivan, P.3
-
26
-
-
0037077040
-
Toxic proteins in neurodegenerative disease
-
Taylor, J. P.; Hardy, J.; Fischbeck, K. H. Toxic proteins in neurodegenerative disease. Science 2002, 296, 1991-1995.
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
27
-
-
6844258835
-
Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients
-
van Leeuwen, F. W.; de Kleijn, D. P.; van den Hurk, H. H.; Neubauer, A.; Sonnemans, M. A.; Sluijs, J. A.; Koycu, S.; Ramdjielal, R. D.; Salehi, A.; Martens, G. J.; Grosveld, F. G.; Peter, J.; Burbach, H.; Hol, E. M. Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients. Science 1998, 279, 242-247.
-
(1998)
Science
, vol.279
, pp. 242-247
-
-
van Leeuwen, F.W.1
de Kleijn, D.P.2
van den Hurk, H.H.3
Neubauer, A.4
Sonnemans, M.A.5
Sluijs, J.A.6
Koycu, S.7
Ramdjielal, R.D.8
Salehi, A.9
Martens, G.J.10
Grosveld, F.G.11
Peter, J.12
Burbach, H.13
Hol, E.M.14
-
28
-
-
33748432548
-
Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration
-
Lee, J. W.; Beebe, K.; Nangle, L. A.; Jang, J.; Longo-Guess, C. M.; Cook, S. A.; Davisson, M. T.; Sundberg, J. P.; Schimmel, P.; Ackerman, S. L. Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. Nature 2006, 443, 50-55.
-
(2006)
Nature
, vol.443
, pp. 50-55
-
-
Lee, J.W.1
Beebe, K.2
Nangle, L.A.3
Jang, J.4
Longo-Guess, C.M.5
Cook, S.A.6
Davisson, M.T.7
Sundberg, J.P.8
Schimmel, P.9
Ackerman, S.L.10
-
29
-
-
4444339833
-
Oxidative DNA damage and disease: Induction, repair and significance
-
Evans, M. D.; Dizdaroglu, M.; Cooke, M. S. Oxidative DNA damage and disease: induction, repair and significance. Mutat. Res. 2004, 567, 1-61.
-
(2004)
Mutat. Res
, vol.567
, pp. 1-61
-
-
Evans, M.D.1
Dizdaroglu, M.2
Cooke, M.S.3
-
30
-
-
32044466239
-
Does measurement of oxidative damage to DNA have clinical significance?
-
Cooke, M. S.; Olinski, R.; Evans, M. D. Does measurement of oxidative damage to DNA have clinical significance? Clin. Chim. Acta 2006, 365, 30-49.
-
(2006)
Clin. Chim. Acta
, vol.365
, pp. 30-49
-
-
Cooke, M.S.1
Olinski, R.2
Evans, M.D.3
-
31
-
-
0022809670
-
Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair
-
Kasai, H.; Crain, P. F.; Kuchino, Y.; Nishimura, S.; Ootsuyama, A.; Tanooka, H. Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis 1986, 7, 1849-1851.
-
(1986)
Carcinogenesis
, vol.7
, pp. 1849-1851
-
-
Kasai, H.1
Crain, P.F.2
Kuchino, Y.3
Nishimura, S.4
Ootsuyama, A.5
Tanooka, H.6
-
32
-
-
0025902273
-
Endogenous mutagens and the causes of aging and cancer
-
Ames, B. N.; Gold, L. S. Endogenous mutagens and the causes of aging and cancer. Mutat. Res. 1991, 250, 3-16.
-
(1991)
Mutat. Res
, vol.250
, pp. 3-16
-
-
Ames, B.N.1
Gold, L.S.2
-
33
-
-
0026772501
-
Redox ribonucleosides. Isolation and characterization of 5-hydroxyuridine, 8-hydroxyguanosine, and 8-hydroxyadenosine from Torula yeast RNA
-
Yanagawa, H.; Ogawa, Y.; Ueno, M. Redox ribonucleosides. Isolation and characterization of 5-hydroxyuridine, 8-hydroxyguanosine, and 8-hydroxyadenosine from Torula yeast RNA. J. Biol. Chem. 1992, 267, 13320-13326.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 13320-13326
-
-
Yanagawa, H.1
Ogawa, Y.2
Ueno, M.3
-
34
-
-
0027170378
-
Methylene blue and rose bengal photoinactivation of RNA bacteriophages: Comparative studies of 8-oxoguanine formation in isolated RNA
-
Schneider, J. E., Jr.; Phillips, J. R.; Pye, Q.; Maidt, M. L.; Price, S.; Floyd, R. A. Methylene blue and rose bengal photoinactivation of RNA bacteriophages: comparative studies of 8-oxoguanine formation in isolated RNA. Arch. Biochem. Biophys. 1993, 301, 91-97.
-
(1993)
Arch. Biochem. Biophys
, vol.301
, pp. 91-97
-
-
Schneider Jr., J.E.1
Phillips, J.R.2
Pye, Q.3
Maidt, M.L.4
Price, S.5
Floyd, R.A.6
-
35
-
-
0029162686
-
Oxidative base damage in RNA detected by reverse transcriptase
-
Rhee, Y.; Valentine, M. R.; Termini, J. Oxidative base damage in RNA detected by reverse transcriptase. Nucleic Acids Res 1995, 23, 3275-3282.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3275-3282
-
-
Rhee, Y.1
Valentine, M.R.2
Termini, J.3
-
36
-
-
0033402065
-
Some unusual nucleic acid bases are products of hydroxyl radical oxidation of DNA and RNA
-
Barciszewski, J.; Barciszewska, M. Z.; Siboska, G.; Rattan, S. I.; Clark, B. F. Some unusual nucleic acid bases are products of hydroxyl radical oxidation of DNA and RNA. Mol. Biol. Rep. 1999, 26, 231-238.
-
(1999)
Mol. Biol. Rep
, vol.26
, pp. 231-238
-
-
Barciszewski, J.1
Barciszewska, M.Z.2
Siboska, G.3
Rattan, S.I.4
Clark, B.F.5
-
37
-
-
0028933255
-
Determination of 8-hydroxydeoxyguanosine by an immunoaffinity chromatography-monoclonal antibody-based ELISA
-
Yin, B.; Whyatt, R. M.; Perera, F. P.; Randall, M. C.; Cooper, T. B.; Santella, R. M. Determination of 8-hydroxydeoxyguanosine by an immunoaffinity chromatography-monoclonal antibody-based ELISA. Free Radic. Biol. Med. 1995, 18, 1023-1032.
-
(1995)
Free Radic. Biol. Med
, vol.18
, pp. 1023-1032
-
-
Yin, B.1
Whyatt, R.M.2
Perera, F.P.3
Randall, M.C.4
Cooper, T.B.5
Santella, R.M.6
-
38
-
-
0026568631
-
Assay of excised oxidative DNA lesions: Isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column
-
Park, E. M.; Shigenaga, M. K.; Degan, P.; Korn, T. S.; Kitzler, J. W.; Wehr, C. M.; Kolachana, P.; Ames, B. N. Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column. Proc. Natl. Acad. Sci. U. S. A. 1992, 89, 3375-3379.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A
, vol.89
, pp. 3375-3379
-
-
Park, E.M.1
Shigenaga, M.K.2
Degan, P.3
Korn, T.S.4
Kitzler, J.W.5
Wehr, C.M.6
Kolachana, P.7
Ames, B.N.8
-
39
-
-
0032911488
-
Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
-
Zhang, J.; Perry, G.; Smith, M. A.; Robertson, D.; Olson, S. J.; Graham, D. G.; Montine, T. J. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am. J. Pathol. 1999, 154, 1423-1429.
-
(1999)
Am. J. Pathol
, vol.154
, pp. 1423-1429
-
-
Zhang, J.1
Perry, G.2
Smith, M.A.3
Robertson, D.4
Olson, S.J.5
Graham, D.G.6
Montine, T.J.7
-
40
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura, A.; Perry, G.; Aliev, G.; Hirai, K.; Takeda, A.; Balraj, E. K.; Jones, P. K.; Ghanbari, H.; Wataya, T.; Shimohama, S.; Chiba, S.; Atwood, C. S.; Petersen, R. B.; Smith, M. A. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol. 2001, 60, 759-767.
-
(2001)
J. Neuropathol. Exp. Neurol
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
41
-
-
0033758324
-
Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome
-
Nunomura, A.; Perry, G.; Pappolla, M. A.; Friedland, R. P.; Hirai, K.; Chiba, S.; Smith, M. A. Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome. J. Neuropathol. Exp. Neurol. 2000, 59, 1011-1017.
-
(2000)
J. Neuropathol. Exp. Neurol
, vol.59
, pp. 1011-1017
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Friedland, R.P.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
42
-
-
0037113341
-
Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies
-
Nunomura, A.; Chiba, S.; Kosaka, K.; Takeda, A.; Castellani, R. J.; Smith, M. A.; Perry, G. Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Neuroreport 2002, 13, 2035-2039.
-
(2002)
Neuroreport
, vol.13
, pp. 2035-2039
-
-
Nunomura, A.1
Chiba, S.2
Kosaka, K.3
Takeda, A.4
Castellani, R.J.5
Smith, M.A.6
Perry, G.7
-
43
-
-
0036236406
-
Oxidative damage to nucleic acids in human prion disease
-
Guentchev, M.; Siedlak, S. L.; Jarius, C.; Tagliavini, F.; Castellani, R. J.; Perry, G.; Smith, M. A.; Budka, H. Oxidative damage to nucleic acids in human prion disease. Neurobiol. Dis. 2002, 9, 275-281.
-
(2002)
Neurobiol. Dis
, vol.9
, pp. 275-281
-
-
Guentchev, M.1
Siedlak, S.L.2
Jarius, C.3
Tagliavini, F.4
Castellani, R.J.5
Perry, G.6
Smith, M.A.7
Budka, H.8
-
44
-
-
0036823978
-
Neurodegenerative mechanisms in subacute sclerosing panencephalitis
-
Hayashi, M.; Arai, N.; Satoh, J.; Suzuki, H.; Katayama, K.; Tamagawa, K.; Morimatsu, Y. Neurodegenerative mechanisms in subacute sclerosing panencephalitis. J. Child Neurol. 2002, 17, 725-730.
-
(2002)
J. Child Neurol
, vol.17
, pp. 725-730
-
-
Hayashi, M.1
Arai, N.2
Satoh, J.3
Suzuki, H.4
Katayama, K.5
Tamagawa, K.6
Morimatsu, Y.7
-
45
-
-
4444302948
-
Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease
-
Nunomura, A.; Chiba, S.; Lippa, C. F.; Cras, P.; Kalaria, R. N.; Takeda, A.; Honda, K.; Smith, M. A.; Perry, G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiol. Dis. 2004, 17, 108-113.
-
(2004)
Neurobiol. Dis
, vol.17
, pp. 108-113
-
-
Nunomura, A.1
Chiba, S.2
Lippa, C.F.3
Cras, P.4
Kalaria, R.N.5
Takeda, A.6
Honda, K.7
Smith, M.A.8
Perry, G.9
-
46
-
-
26444549058
-
Redox metals and oxidative abnormalities in human prion diseases
-
Petersen, R. B.; Siedlak, S. L.; Lee, H. G.; Kim, Y. S.; Nunomura, A.; Tagliavini, F.; Ghetti, B.; Cras, P.; Moreira, P. I.; Castellani, R. J.; Guentchev, M.; Budka, H.; Ironside, J. W.; Gambetti, P.; Smith, M. A.; Perry, G. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathol 2005, 110, 232-238.
-
(2005)
Acta Neuropathol
, vol.110
, pp. 232-238
-
-
Petersen, R.B.1
Siedlak, S.L.2
Lee, H.G.3
Kim, Y.S.4
Nunomura, A.5
Tagliavini, F.6
Ghetti, B.7
Cras, P.8
Moreira, P.I.9
Castellani, R.J.10
Guentchev, M.11
Budka, H.12
Ironside, J.W.13
Gambetti, P.14
Smith, M.A.15
Perry, G.16
-
47
-
-
11144242851
-
Oxidative nucleotide damage and superoxide dismutase expression in the brains of xeroderma pigmentosum group A and Cockayne syndrome
-
Hayashi, M.; Araki, S.; Kohyama, J.; Shioda, K.; Fukatsu, R. Oxidative nucleotide damage and superoxide dismutase expression in the brains of xeroderma pigmentosum group A and Cockayne syndrome. Brain Dev. 2005, 27, 34-38.
-
(2005)
Brain Dev
, vol.27
, pp. 34-38
-
-
Hayashi, M.1
Araki, S.2
Kohyama, J.3
Shioda, K.4
Fukatsu, R.5
-
48
-
-
0038451600
-
Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles
-
Tateyama, M.; Takeda, A.; Onodera, Y.; Matsuzaki, M.; Hasegawa, T.; Nunomura, A.; Hirai, K.; Perry, G.; Smith, M. A.; Itoyama, Y. Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles. Acta Neuropathol. (Berl). 2003, 105, 581-585.
-
(2003)
Acta Neuropathol. (Berl)
, vol.105
, pp. 581-585
-
-
Tateyama, M.1
Takeda, A.2
Onodera, Y.3
Matsuzaki, M.4
Hasegawa, T.5
Nunomura, A.6
Hirai, K.7
Perry, G.8
Smith, M.A.9
Itoyama, Y.10
-
49
-
-
2942601090
-
Reactive oxygen species induce RNA damage in human atherosclerosis
-
Martinet, W.; de Meyer, G. R.; Herman, A. G.; Kockx, M. M. Reactive oxygen species induce RNA damage in human atherosclerosis. Eur. J. Clin. Invest. 2004, 34, 323-327.
-
(2004)
Eur. J. Clin. Invest
, vol.34
, pp. 323-327
-
-
Martinet, W.1
de Meyer, G.R.2
Herman, A.G.3
Kockx, M.M.4
-
50
-
-
43849083422
-
Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy
-
in press
-
Hofer, T.; Marzetti, E.; Xu, J.; Seo, A. Y.; Gulec, S.; Knutson, M. D.; Leeuwenburgh, C.; Dupont-Versteegden, E. E. Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy. Exp. Gerontol. 2008, in press.
-
(2008)
Exp. Gerontol
-
-
Hofer, T.1
Marzetti, E.2
Xu, J.3
Seo, A.Y.4
Gulec, S.5
Knutson, M.D.6
Leeuwenburgh, C.7
Dupont-Versteegden, E.E.8
-
51
-
-
0038417076
-
The identification and characterization of oxidized RNAs in Alzheimer's disease
-
Shan, X.; Tashiro, H.; Lin, C. L. The identification and characterization of oxidized RNAs in Alzheimer's disease. J. Neurosci. 2003, 23, 4913-4921.
-
(2003)
J. Neurosci
, vol.23
, pp. 4913-4921
-
-
Shan, X.1
Tashiro, H.2
Lin, C.L.3
-
52
-
-
20444383489
-
Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron
-
Honda, K.; Smith, M. A.; Zhu, X.; Baus, D.; Merrick, W. C.; Tartakoff, A. M.; Hattier, T.; Harris, P. L.; Siedlak, S. L.; Fujioka, H.; Liu, Q.; Moreira, P. I.; Miller, F. P.; Nunomura, A.; Shimohama, S.; Perry, G. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J. Biol. Chem. 2005, 280, 20978-20986.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 20978-20986
-
-
Honda, K.1
Smith, M.A.2
Zhu, X.3
Baus, D.4
Merrick, W.C.5
Tartakoff, A.M.6
Hattier, T.7
Harris, P.L.8
Siedlak, S.L.9
Fujioka, H.10
Liu, Q.11
Moreira, P.I.12
Miller, F.P.13
Nunomura, A.14
Shimohama, S.15
Perry, G.16
-
53
-
-
27144494994
-
Ribosome dysfunction is an early event in Alzheimer's disease
-
Ding, Q.; Markesbery, W. R.; Chen, Q.; Li, F.; Keller, J. N. Ribosome dysfunction is an early event in Alzheimer's disease. J. Neurosci. 2005, 25, 9171-9175.
-
(2005)
J. Neurosci
, vol.25
, pp. 9171-9175
-
-
Ding, Q.1
Markesbery, W.R.2
Chen, Q.3
Li, F.4
Keller, J.N.5
-
54
-
-
33745096512
-
Decreased RNA, and increased RNA oxidation, in ribosomes from early Alzheimer's disease
-
Ding, Q.; Markesbery, W. R.; Cecarini, V.; Keller, J. N. Decreased RNA, and increased RNA oxidation, in ribosomes from early Alzheimer's disease. Neurochem. Res. 2006, 31, 705-710.
-
(2006)
Neurochem. Res
, vol.31
, pp. 705-710
-
-
Ding, Q.1
Markesbery, W.R.2
Cecarini, V.3
Keller, J.N.4
-
55
-
-
33645961571
-
Quantification of oxidized RNAs in Alzheimer's disease
-
Shan, X.; Lin, C. L. Quantification of oxidized RNAs in Alzheimer's disease. Neurobiol. Aging 2006, 27, 657-662.
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 657-662
-
-
Shan, X.1
Lin, C.L.2
-
56
-
-
0037010314
-
Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease
-
Abe, T.; Tohgi, H.; Isobe, C.; Murata, T.; Sato, C. Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease. J. Neurosci. Res. 2002, 70, 447-450.
-
(2002)
J. Neurosci. Res
, vol.70
, pp. 447-450
-
-
Abe, T.1
Tohgi, H.2
Isobe, C.3
Murata, T.4
Sato, C.5
-
57
-
-
0036197296
-
Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy
-
Kikuchi, A.; Takeda, A.; Onodera, H.; Kimpara, T.; Hisanaga, K.; Sato, N.; Nunomura, A.; Castellani, R. J.; Perry, G.; Smith, M. A.; Itoyama, Y. Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiol. Dis. 2002, 9, 244-248.
-
(2002)
Neurobiol. Dis
, vol.9
, pp. 244-248
-
-
Kikuchi, A.1
Takeda, A.2
Onodera, H.3
Kimpara, T.4
Hisanaga, K.5
Sato, N.6
Nunomura, A.7
Castellani, R.J.8
Perry, G.9
Smith, M.A.10
Itoyama, Y.11
-
58
-
-
0037448323
-
Alteration of 8-hydroxyguanosine concentrations in the cerebrospinal fluid and serum from patients with Parkinson's disease
-
Abe, T.; Isobe, C.; Murata, T.; Sato, C.; Tohgi, H. Alteration of 8-hydroxyguanosine concentrations in the cerebrospinal fluid and serum from patients with Parkinson's disease. Neurosci. Lett. 2003, 336, 105-108.
-
(2003)
Neurosci. Lett
, vol.336
, pp. 105-108
-
-
Abe, T.1
Isobe, C.2
Murata, T.3
Sato, C.4
Tohgi, H.5
-
59
-
-
0037133283
-
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid
-
Liu, J.; Head, E.; Gharib, A. M.; Yuan, W.; Ingersoll, R. T.; Hagen, T. M.; Cotman, C. W.; Ames, B. N. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid. Proc. Natl. Acad. Sci. U. S. A. 2002, 99, 2356-2361.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A
, vol.99
, pp. 2356-2361
-
-
Liu, J.1
Head, E.2
Gharib, A.M.3
Yuan, W.4
Ingersoll, R.T.5
Hagen, T.M.6
Cotman, C.W.7
Ames, B.N.8
-
60
-
-
0038132134
-
Intermittent hypoxia is associated with oxidative stress and spatial learning deficits in the rat
-
Row, B. W.; Liu, R.; Xu, W.; Kheirandish, L.; Gozal, D. Intermittent hypoxia is associated with oxidative stress and spatial learning deficits in the rat. Am. J. Respir. Crit. Care Med. 2003, 167, 1548-1553.
-
(2003)
Am. J. Respir. Crit. Care Med
, vol.167
, pp. 1548-1553
-
-
Row, B.W.1
Liu, R.2
Xu, W.3
Kheirandish, L.4
Gozal, D.5
-
61
-
-
33644953588
-
-
Yamaguchi, H.; Kajitani, K.; Dan, Y.; Furuichi, M.; Ohno, M.; Sakumi, K.; Kang, D.; Nakabeppu, Y. MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Cell Death Differ. 2006, 13, 551-563.
-
Yamaguchi, H.; Kajitani, K.; Dan, Y.; Furuichi, M.; Ohno, M.; Sakumi, K.; Kang, D.; Nakabeppu, Y. MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Cell Death Differ. 2006, 13, 551-563.
-
-
-
-
62
-
-
5344242475
-
Urinary excretion of DNA repair products correlates with metabolic rates as well as with maximum life spans of different mammalian species
-
Foksinski, M.; Rozalski, R.; Guz, J.; Ruszkowska, B.; Sztukowska, P.; Piwowarski, M.; Klungland, A.; Olinski, R. Urinary excretion of DNA repair products correlates with metabolic rates as well as with maximum life spans of different mammalian species. Free Radic. Biol. Med. 2004, 37, 1449-1454.
-
(2004)
Free Radic. Biol. Med
, vol.37
, pp. 1449-1454
-
-
Foksinski, M.1
Rozalski, R.2
Guz, J.3
Ruszkowska, B.4
Sztukowska, P.5
Piwowarski, M.6
Klungland, A.7
Olinski, R.8
-
63
-
-
0000340348
-
-
Javitch, J. A.; D'Amato, R. J.; Strittmatter, S. M.; Snyder, S. H. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc. Natl. Acad. Sci. U. S. A. 1985, 82, 2173-2177.
-
Javitch, J. A.; D'Amato, R. J.; Strittmatter, S. M.; Snyder, S. H. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc. Natl. Acad. Sci. U. S. A. 1985, 82, 2173-2177.
-
-
-
-
64
-
-
20344388665
-
Kainic acid-mediated excitotoxicity as a model for neurodegeneration
-
Wang, Q.; Yu, S.; Simonyi, A.; Sun, G. Y.; Sun, A. Y. Kainic acid-mediated excitotoxicity as a model for neurodegeneration. Mol. Neurobiol. 2005, 31, 3-16.
-
(2005)
Mol. Neurobiol
, vol.31
, pp. 3-16
-
-
Wang, Q.1
Yu, S.2
Simonyi, A.3
Sun, G.Y.4
Sun, A.Y.5
-
65
-
-
32544458774
-
MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity
-
Kajitani, K.; Yamaguchi, H.; Dan, Y.; Furuichi, M.; Kang, D.; Nakabeppu, Y. MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity. J. Neurosci. 2006, 26, 1688-1698.
-
(2006)
J. Neurosci
, vol.26
, pp. 1688-1698
-
-
Kajitani, K.1
Yamaguchi, H.2
Dan, Y.3
Furuichi, M.4
Kang, D.5
Nakabeppu, Y.6
-
66
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D. R.; Siddique, T.; Patterson, D.; Figlewicz, D. A.; Sapp, P.; Hentati, A.; Donaldson, D.; Goto, J.; O'Regan, J. P.; Deng, H. X.; et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993, 362, 59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
67
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
-
Gurney, M. E.; Pu, H.; Chiu, A. Y.; Dal Canto, M. C.; Polchow, C. Y.; Alexander, D. D.; Caliendo, J.; Hentati, A.; Kwon, Y. W.; Deng, H. X.; et al. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 1994, 264, 1772-1775.
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.X.10
-
68
-
-
44649172328
-
-
Chang, Y.; Shan, X.; Lin, C. L. RNA oxidation is an early event preceding motor neuron death in ALS. Soc. Neurosci. Abstr. 2004, 96.93.
-
Chang, Y.; Shan, X.; Lin, C. L. RNA oxidation is an early event preceding motor neuron death in ALS. Soc. Neurosci. Abstr. 2004, 96.93.
-
-
-
-
69
-
-
9744223523
-
Proteasome inhibition increases DNA and RNA oxidation in astrocyte and neuron cultures
-
Ding, Q.; Dimayuga, E.; Markesbery, W. R.; Keller, J. N. Proteasome inhibition increases DNA and RNA oxidation in astrocyte and neuron cultures. J. Neurochem. 2004, 91, 1211-1218.
-
(2004)
J. Neurochem
, vol.91
, pp. 1211-1218
-
-
Ding, Q.1
Dimayuga, E.2
Markesbery, W.R.3
Keller, J.N.4
-
70
-
-
34548476954
-
Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression
-
Shan, X.; Chang, Y.; Lin, C. L. Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression. FASEB J. 2007, 21, 2753-2764.
-
(2007)
FASEB J
, vol.21
, pp. 2753-2764
-
-
Shan, X.1
Chang, Y.2
Lin, C.L.3
-
71
-
-
33845610586
-
Interplay between protein synthesis and degradation in the CNS: Physiological and pathological implications
-
Ding, Q.; Cecarini, V.; Keller, J. N. Interplay between protein synthesis and degradation in the CNS: physiological and pathological implications. Trends Neurosci. 2007, 30, 31-36.
-
(2007)
Trends Neurosci
, vol.30
, pp. 31-36
-
-
Ding, Q.1
Cecarini, V.2
Keller, J.N.3
-
72
-
-
16844382331
-
Evidence of increased oxidative damage in subjects with mild cognitive impairment
-
Keller, J. N.; Schmitt, F. A.; Scheff, S. W.; Ding, Q.; Chen, Q.; Butterfield, D. A.; Markesbery, W. R. Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology 2005, 64, 1152-1156.
-
(2005)
Neurology
, vol.64
, pp. 1152-1156
-
-
Keller, J.N.1
Schmitt, F.A.2
Scheff, S.W.3
Ding, Q.4
Chen, Q.5
Butterfield, D.A.6
Markesbery, W.R.7
-
73
-
-
34247142905
-
Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: Implications for the role of nitration in the progression of Alzheimer's disease
-
Butterfield, D. A.; Reed, T. T.; Perluigi, M.; De Marco, C.; Coccia, R.; Keller, J. N.; Markesbery, W. R.; Sultana, R. Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: implications for the role of nitration in the progression of Alzheimer's disease. Brain Res. 2007, 1148, 243-248.
-
(2007)
Brain Res
, vol.1148
, pp. 243-248
-
-
Butterfield, D.A.1
Reed, T.T.2
Perluigi, M.3
De Marco, C.4
Coccia, R.5
Keller, J.N.6
Markesbery, W.R.7
Sultana, R.8
-
74
-
-
0036284936
-
Increase of brain oxidative stress in mild cognitive impairment: A possible predictor of Alzheimer disease
-
Pratico, D.; Clark, C. M.; Liun, F.; Rokach, J.; Lee, V. Y.; Trojanowski, J. Q. Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease. Arch. Neurol. 2002, 59, 972-976.
-
(2002)
Arch. Neurol
, vol.59
, pp. 972-976
-
-
Pratico, D.1
Clark, C.M.2
Liun, F.3
Rokach, J.4
Lee, V.Y.5
Trojanowski, J.Q.6
-
75
-
-
13644270565
-
Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients
-
Migliore, L.; Fontana, I.; Trippi, F.; Colognato, R.; Coppede, F.; Tognoni, G.; Nucciarone, B.; Siciliano, G. Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients. Neurobiol. Aging 2005, 26, 567-573.
-
(2005)
Neurobiol. Aging
, vol.26
, pp. 567-573
-
-
Migliore, L.1
Fontana, I.2
Trippi, F.3
Colognato, R.4
Coppede, F.5
Tognoni, G.6
Nucciarone, B.7
Siciliano, G.8
-
76
-
-
0042591280
-
Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease
-
Rinaldi, P.; Polidori, M. C.; Metastasio, A.; Mariani, E.; Mattioli, P.; Cherubini, A.; Catani, M.; Cecchetti, R.; Senin, U.; Mecocci, P. Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease. Neurobiol. Aging 2003, 24, 915-919.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 915-919
-
-
Rinaldi, P.1
Polidori, M.C.2
Metastasio, A.3
Mariani, E.4
Mattioli, P.5
Cherubini, A.6
Catani, M.7
Cecchetti, R.8
Senin, U.9
Mecocci, P.10
-
77
-
-
29844435497
-
Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease
-
Guidi, I.; Galimberti, D.; Lonati, S.; Novembrino, C.; Bamonti, F.; Tiriticco, M.; Fenoglio, C.; Venturelli, E.; Baron, P.; Bresolin, N.; Scarpini, E. Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease. Neurobiol. Aging 2006, 27, 262-269.
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 262-269
-
-
Guidi, I.1
Galimberti, D.2
Lonati, S.3
Novembrino, C.4
Bamonti, F.5
Tiriticco, M.6
Fenoglio, C.7
Venturelli, E.8
Baron, P.9
Bresolin, N.10
Scarpini, E.11
-
78
-
-
33745486884
-
Therapeutic options in Alzheimer's disease
-
Moreira, P. I.; Zhu, X.; Nunomura, A.; Smith, M. A.; Perry, G. Therapeutic options in Alzheimer's disease. Expert Rev. Neurother. 2006, 6, 897-910.
-
(2006)
Expert Rev. Neurother
, vol.6
, pp. 897-910
-
-
Moreira, P.I.1
Zhu, X.2
Nunomura, A.3
Smith, M.A.4
Perry, G.5
-
79
-
-
33847776693
-
Prevention and treatment of Alzheimer disease and aging: Antioxidants
-
Liu, Q.; Xie, F.; Rolston, R.; Moreira, P. I.; Nunomura, A.; Zhu, X.; Smith, M. A.; Perry, G. Prevention and treatment of Alzheimer disease and aging: antioxidants. Mini Rev. Med. Chem. 2007, 7, 171-180.
-
(2007)
Mini Rev. Med. Chem
, vol.7
, pp. 171-180
-
-
Liu, Q.1
Xie, F.2
Rolston, R.3
Moreira, P.I.4
Nunomura, A.5
Zhu, X.6
Smith, M.A.7
Perry, G.8
-
80
-
-
0032847544
-
In situ methods for detection and localization of markers of oxidative stress: Application in neurodegenerative disorders
-
Sayre, L. M.; Perry, G.; Smith, M. A. In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders. Methods Enzymol. 1999, 309, 133-152.
-
(1999)
Methods Enzymol
, vol.309
, pp. 133-152
-
-
Sayre, L.M.1
Perry, G.2
Smith, M.A.3
-
81
-
-
0029982815
-
Oxidative damage in Alzheimer's
-
Smith, M. A.; Perry, G.; Richey, P. L.; Sayre, L. M.; Anderson, V. E.; Beal, M. F.; Kowall, N. Oxidative damage in Alzheimer's. Nature 1996, 382, 120-121.
-
(1996)
Nature
, vol.382
, pp. 120-121
-
-
Smith, M.A.1
Perry, G.2
Richey, P.L.3
Sayre, L.M.4
Anderson, V.E.5
Beal, M.F.6
Kowall, N.7
-
82
-
-
0030989545
-
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
-
Sayre, L. M.; Zelasko, D. A.; Harris, P. L.; Perry, G.; Salomon, R. G.; Smith, M. A. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J. Neurochem. 1997, 68, 2092-2097.
-
(1997)
J. Neurochem
, vol.68
, pp. 2092-2097
-
-
Sayre, L.M.1
Zelasko, D.A.2
Harris, P.L.3
Perry, G.4
Salomon, R.G.5
Smith, M.A.6
-
83
-
-
34247868874
-
Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease
-
Casadesus, G.; Smith, M. A.; Basu, S.; Hua, J.; Capobianco, D. E.; Siedlak, S. L.; Zhu, X.; Perry, G. Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. Mol. Neurodegener. 2007, 2, 2.
-
(2007)
Mol. Neurodegener
, vol.2
, pp. 2
-
-
Casadesus, G.1
Smith, M.A.2
Basu, S.3
Hua, J.4
Capobianco, D.E.5
Siedlak, S.L.6
Zhu, X.7
Perry, G.8
-
84
-
-
0035879693
-
Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine
-
Castellani, R. J.; Harris, P. L.; Sayre, L. M.; Fujii, J.; Taniguchi, N.; Vitek, M. P.; Founds, H.; Atwood, C. S.; Perry, G.; Smith, M. A. Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free Radic. Biol. Med. 2001, 31, 175-180.
-
(2001)
Free Radic. Biol. Med
, vol.31
, pp. 175-180
-
-
Castellani, R.J.1
Harris, P.L.2
Sayre, L.M.3
Fujii, J.4
Taniguchi, N.5
Vitek, M.P.6
Founds, H.7
Atwood, C.S.8
Perry, G.9
Smith, M.A.10
-
85
-
-
0027686249
-
Oxidative stress, glutamate, and neurodegenerative disorders
-
Coyle, J. T.; Puttfarcken, P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 1993, 262, 689-695.
-
(1993)
Science
, vol.262
, pp. 689-695
-
-
Coyle, J.T.1
Puttfarcken, P.2
-
86
-
-
0036304650
-
Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior
-
Mattson, M. P.; Chan, S. L.; Duan, W. Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior. Physiol. Rev. 2002, 82, 637-672.
-
(2002)
Physiol. Rev
, vol.82
, pp. 637-672
-
-
Mattson, M.P.1
Chan, S.L.2
Duan, W.3
-
87
-
-
0026754574
-
Reactive oxygen species and the central nervous system
-
Halliwell, B. Reactive oxygen species and the central nervous system. J. Neurochem. 1992, 59, 1609-1623.
-
(1992)
J. Neurochem
, vol.59
, pp. 1609-1623
-
-
Halliwell, B.1
-
88
-
-
0024437033
-
Genetic toxicology of oxygen
-
Joenje, H. Genetic toxicology of oxygen. Mutat. Res. 1989, 219, 193-208.
-
(1989)
Mutat. Res
, vol.219
, pp. 193-208
-
-
Joenje, H.1
-
89
-
-
0021105282
-
Superoxide anion permeability of phospholipid membranes and chloroplast thylakoids
-
Takahashi, M. A.; Asada, K. Superoxide anion permeability of phospholipid membranes and chloroplast thylakoids. Arch. Biochem. Biophys. 1983, 226, 558-566.
-
(1983)
Arch. Biochem. Biophys
, vol.226
, pp. 558-566
-
-
Takahashi, M.A.1
Asada, K.2
-
90
-
-
0026332035
-
Does hydrogen peroxide exist "free" in biological systems?
-
Schubert, J.; Wilmer, J. W. Does hydrogen peroxide exist "free" in biological systems? Free Radic. Biol. Med. 1991, 11, 545-555.
-
(1991)
Free Radic. Biol. Med
, vol.11
, pp. 545-555
-
-
Schubert, J.1
Wilmer, J.W.2
-
91
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai, K.; Aliev, G.; Nunomura, A.; Fujioka, H.; Russell, R. L.; Atwood, C. S.; Johnson, A. B.; Kress, Y.; Vinters, H. V.; Tabaton, M.; Shimohama, S.; Cash, A. D.; Siedlak, S. L.; Harris, P. L.; Jones, P. K.; Petersen, R. B.; Perry, G.; Smith, M. A. Mitochondrial abnormalities in Alzheimer's disease. J. Neurosci. 2001, 21, 3017-3023.
-
(2001)
J. Neurosci
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
Shimohama, S.11
Cash, A.D.12
Siedlak, S.L.13
Harris, P.L.14
Jones, P.K.15
Petersen, R.B.16
Perry, G.17
Smith, M.A.18
-
92
-
-
0036044164
-
Reactive oxygen: Its sources and significance in Alzheimer disease
-
Perry, G.; Nunomura, A.; Cash, A. D.; Taddeo, M. A.; Hirai, K.; Aliev, G.; Avila, J.; Wataya, T.; Shimohama, S.; Atwood, C. S.; Smith, M. A. Reactive oxygen: its sources and significance in Alzheimer disease. J. Neural Transm. Suppl. 2002, 69-75.
-
(2002)
J. Neural Transm. Suppl
, pp. 69-75
-
-
Perry, G.1
Nunomura, A.2
Cash, A.D.3
Taddeo, M.A.4
Hirai, K.5
Aliev, G.6
Avila, J.7
Wataya, T.8
Shimohama, S.9
Atwood, C.S.10
Smith, M.A.11
-
93
-
-
18744374615
-
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
-
Perry, G.; Nunomura, A.; Hirai, K.; Zhu, X.; Perez, M.; Avila, J.; Castellani, R. J.; Atwood, C. S.; Aliev, G.; Sayre, L. M.; Takeda, A.; Smith, M. A. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic. Biol. Med. 2002, 33, 1475-1479.
-
(2002)
Free Radic. Biol. Med
, vol.33
, pp. 1475-1479
-
-
Perry, G.1
Nunomura, A.2
Hirai, K.3
Zhu, X.4
Perez, M.5
Avila, J.6
Castellani, R.J.7
Atwood, C.S.8
Aliev, G.9
Sayre, L.M.10
Takeda, A.11
Smith, M.A.12
-
94
-
-
0033751421
-
Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease
-
Smith, M. A.; Nunomura, A.; Zhu, X.; Takeda, A.; Perry, G. Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease. Antioxid. Redox Signal. 2000, 2, 413-420.
-
(2000)
Antioxid. Redox Signal
, vol.2
, pp. 413-420
-
-
Smith, M.A.1
Nunomura, A.2
Zhu, X.3
Takeda, A.4
Perry, G.5
-
95
-
-
0036298182
-
Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders
-
Gu, G.; Reyes, P. E.; Golden, G. T.; Woltjer, R. L.; Hulette, C.; Montine, T. J.; Zhang, J. Mitochondrial DNA deletions/rearrangements in parkinson disease and related neurodegenerative disorders. J. Neuropathol. Exp. Neurol. 2002, 61, 634-639.
-
(2002)
J. Neuropathol. Exp. Neurol
, vol.61
, pp. 634-639
-
-
Gu, G.1
Reyes, P.E.2
Golden, G.T.3
Woltjer, R.L.4
Hulette, C.5
Montine, T.J.6
Zhang, J.7
-
96
-
-
0025254401
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira, A. H.; Cooper, J. M.; Dexter, D.; Clark, J. B.; Jenner, P.; Marsden, C. D. Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 1990, 54, 823-827.
-
(1990)
J. Neurochem
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
97
-
-
0023804321
-
Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain
-
Sofic, E.; Riederer, P.; Heinsen, H.; Beckmann, H.; Reynolds, G. P.; Hebenstreit, G.; Youdim, M. B. Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain. J. Neural Transm. 1988, 74, 199-205.
-
(1988)
J. Neural Transm
, vol.74
, pp. 199-205
-
-
Sofic, E.1
Riederer, P.2
Heinsen, H.3
Beckmann, H.4
Reynolds, G.P.5
Hebenstreit, G.6
Youdim, M.B.7
-
98
-
-
0036279410
-
Echogenicity of the substantia nigra: Association with increased iron content and marker for susceptibility to nigrostriatal injury
-
Berg, D.; Roggendorf, W.; Schroder, U.; Klein, R.; Tatschner, T.; Benz, P.; Tucha, O.; Preier, M.; Lange, K. W.; Reiners, K.; Gerlach, M.; Becker, G. Echogenicity of the substantia nigra: association with increased iron content and marker for susceptibility to nigrostriatal injury. Arch. Neurol. 2002, 59, 999-1005.
-
(2002)
Arch. Neurol
, vol.59
, pp. 999-1005
-
-
Berg, D.1
Roggendorf, W.2
Schroder, U.3
Klein, R.4
Tatschner, T.5
Benz, P.6
Tucha, O.7
Preier, M.8
Lange, K.W.9
Reiners, K.10
Gerlach, M.11
Becker, G.12
-
99
-
-
22444438839
-
Mammalian enzymes for preventing transcriptional errors caused by oxidative damage
-
Ishibashi, T.; Hayakawa, H.; Ito, R.; Miyazawa, M.; Yamagata, Y.; Sekiguchi, M. Mammalian enzymes for preventing transcriptional errors caused by oxidative damage. Nucleic Acids Res 2005, 33, 3779-3784.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 3779-3784
-
-
Ishibashi, T.1
Hayakawa, H.2
Ito, R.3
Miyazawa, M.4
Yamagata, Y.5
Sekiguchi, M.6
-
100
-
-
0030879766
-
Counteraction by MutT protein of transcriptional errors caused by oxidative damage
-
Taddei, F.; Hayakawa, H.; Bouton, M.; Cirinesi, A.; Matic, I.; Sekiguchi, M.; Radman, M. Counteraction by MutT protein of transcriptional errors caused by oxidative damage. Science 1997, 278, 128-130.
-
(1997)
Science
, vol.278
, pp. 128-130
-
-
Taddei, F.1
Hayakawa, H.2
Bouton, M.3
Cirinesi, A.4
Matic, I.5
Sekiguchi, M.6
Radman, M.7
-
101
-
-
33846090651
-
Oxidized messenger RNA induces translation errors
-
Tanaka, M.; Chock, P. B.; Stadtman, E. R. Oxidized messenger RNA induces translation errors. Proc. Natl. Acad. Sci. U. S. A. 2007, 104, 66-71.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A
, vol.104
, pp. 66-71
-
-
Tanaka, M.1
Chock, P.B.2
Stadtman, E.R.3
-
102
-
-
33748312314
-
Quantification of RNA damage by reverse transcription polymerase chain reactions
-
Gong, X.; Tao, R.; Li, Z. Quantification of RNA damage by reverse transcription polymerase chain reactions. Anal. Biochem. 2006, 357, 58-67.
-
(2006)
Anal. Biochem
, vol.357
, pp. 58-67
-
-
Gong, X.1
Tao, R.2
Li, Z.3
-
103
-
-
0038274522
-
RNA repair: Damage control
-
Bellacosa, A.; Moss, E. G. RNA repair: damage control. Curr. Biol. 2003, 13, R482-484.
-
(2003)
Curr. Biol
, vol.13
-
-
Bellacosa, A.1
Moss, E.G.2
-
104
-
-
32644435694
-
Degradation of RNA in bacteria: Comparison of mRNA and stable RNA
-
Deutscher, M. P. Degradation of RNA in bacteria: comparison of mRNA and stable RNA. Nucleic Acids Res 2006, 34, 659-666.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 659-666
-
-
Deutscher, M.P.1
-
105
-
-
0037968357
-
Decapping and decay of messenger RNA occur in cytoplasmic processing bodies
-
Sheth, U.; Parker, R. Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 2003, 300, 805-808.
-
(2003)
Science
, vol.300
, pp. 805-808
-
-
Sheth, U.1
Parker, R.2
-
106
-
-
33947726212
-
-
Sweet, T. J.; Boyer, B.; Hu, W.; Baker, K. E.; Coller, J. Microtubule disruption stimulates P-body formation. RNA 2007, 13, 493-502.
-
Sweet, T. J.; Boyer, B.; Hu, W.; Baker, K. E.; Coller, J. Microtubule disruption stimulates P-body formation. RNA 2007, 13, 493-502.
-
-
-
-
107
-
-
22344455246
-
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling
-
Kedersha, N.; Stoecklin, G.; Ayodele, M.; Yacono, P.; Lykke-Andersen, J.; Fritzler, M. J.; Scheuner, D.; Kaufman, R. J.; Golan, D. E.; Anderson, P. Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J. Cell Biol. 2005, 169, 871-884.
-
(2005)
J. Cell Biol
, vol.169
, pp. 871-884
-
-
Kedersha, N.1
Stoecklin, G.2
Ayodele, M.3
Yacono, P.4
Lykke-Andersen, J.5
Fritzler, M.J.6
Scheuner, D.7
Kaufman, R.J.8
Golan, D.E.9
Anderson, P.10
-
108
-
-
0037456369
-
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA
-
Aas, P. A.; Otterlei, M.; Falnes, P. O.; Vagbo, C. B.; Skorpen, F.; Akbari, M.; Sundheim, O.; Bjoras, M.; Slupphaug, G.; Seeberg, E.; Krokan, H. E. Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA. Nature 2003, 421, 859-863.
-
(2003)
Nature
, vol.421
, pp. 859-863
-
-
Aas, P.A.1
Otterlei, M.2
Falnes, P.O.3
Vagbo, C.B.4
Skorpen, F.5
Akbari, M.6
Sundheim, O.7
Bjoras, M.8
Slupphaug, G.9
Seeberg, E.10
Krokan, H.E.11
-
109
-
-
2542476302
-
Novel aspects of macromolecular repair and relationship to human disease
-
Krokan, H. E.; Kavli, B.; Slupphaug, G. Novel aspects of macromolecular repair and relationship to human disease. J. Mol. Med. 2004, 82, 280-297.
-
(2004)
J. Mol. Med
, vol.82
, pp. 280-297
-
-
Krokan, H.E.1
Kavli, B.2
Slupphaug, G.3
-
110
-
-
2342634253
-
Biological significance of the defense mechanisms against oxidative damage in nucleic acids caused by reactive oxygen species: From mitochondria to nuclei
-
Nakabeppu, Y.; Tsuchimoto, D.; Ichinoe, A.; Ohno, M.; Ide, Y.; Hirano, S.; Yoshimura, D.; Tominaga, Y.; Furuichi, M.; Sakumi, K. Biological significance of the defense mechanisms against oxidative damage in nucleic acids caused by reactive oxygen species: from mitochondria to nuclei. Ann. N. Y. Acad. Sci. 2004, 1011, 101-111.
-
(2004)
Ann. N. Y. Acad. Sci
, vol.1011
, pp. 101-111
-
-
Nakabeppu, Y.1
Tsuchimoto, D.2
Ichinoe, A.3
Ohno, M.4
Ide, Y.5
Hirano, S.6
Yoshimura, D.7
Tominaga, Y.8
Furuichi, M.9
Sakumi, K.10
-
111
-
-
0033596906
-
Metabolic fate of oxidized guanine ribonucleotides in mammalian cells
-
Hayakawa, H.; Hofer, A.; Thelander, L.; Kitajima, S.; Cai, Y.; Oshiro, S.; Yakushiji, H.; Nakabeppu, Y.; Kuwano, M.; Sekiguchi, M. Metabolic fate of oxidized guanine ribonucleotides in mammalian cells. Biochemistry (Mosc). 1999, 38, 3610-3614.
-
(1999)
Biochemistry (Mosc)
, vol.38
, pp. 3610-3614
-
-
Hayakawa, H.1
Hofer, A.2
Thelander, L.3
Kitajima, S.4
Cai, Y.5
Oshiro, S.6
Yakushiji, H.7
Nakabeppu, Y.8
Kuwano, M.9
Sekiguchi, M.10
-
112
-
-
33745257002
-
MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides
-
Nakabeppu, Y.; Kajitani, K.; Sakamoto, K.; Yamaguchi, H.; Tsuchimoto, D. MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides. DNA Repair (Amst.) 2006, 5, 761-772.
-
(2006)
DNA Repair (Amst.)
, vol.5
, pp. 761-772
-
-
Nakabeppu, Y.1
Kajitani, K.2
Sakamoto, K.3
Yamaguchi, H.4
Tsuchimoto, D.5
-
113
-
-
17844405031
-
Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools
-
Ito, R.; Hayakawa, H.; Sekiguchi, M.; Ishibashi, T. Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools. Biochemistry (Mosc). 2005, 44, 6670-6674.
-
(2005)
Biochemistry (Mosc)
, vol.44
, pp. 6670-6674
-
-
Ito, R.1
Hayakawa, H.2
Sekiguchi, M.3
Ishibashi, T.4
-
114
-
-
0035903269
-
Expression of hMTH1 in the hippocampi of control and Alzheimer's disease
-
Furuta, A.; Iida, T.; Nakabeppu, Y.; Iwaki, T. Expression of hMTH1 in the hippocampi of control and Alzheimer's disease. Neuroreport 2001, 12, 2895-2899.
-
(2001)
Neuroreport
, vol.12
, pp. 2895-2899
-
-
Furuta, A.1
Iida, T.2
Nakabeppu, Y.3
Iwaki, T.4
-
115
-
-
0032709404
-
Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease
-
Shimura-Miura, H.; Hattori, N.; Kang, D.; Miyako, K.; Nakabeppu, Y.; Mizuno, Y. Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease. Ann. Neurol. 1999, 46, 920-924.
-
(1999)
Ann. Neurol
, vol.46
, pp. 920-924
-
-
Shimura-Miura, H.1
Hattori, N.2
Kang, D.3
Miyako, K.4
Nakabeppu, Y.5
Mizuno, Y.6
-
116
-
-
0035928817
-
Specific binding of 8-oxoguanine-containing RNA to polynucleotide phosphorylase protein
-
Hayakawa, H.; Kuwano, M.; Sekiguchi, M. Specific binding of 8-oxoguanine-containing RNA to polynucleotide phosphorylase protein. Biochemistry (Mosc). 2001, 40, 9977-9982.
-
(2001)
Biochemistry (Mosc)
, vol.40
, pp. 9977-9982
-
-
Hayakawa, H.1
Kuwano, M.2
Sekiguchi, M.3
-
117
-
-
33744752455
-
Human polynucleotide phosphorylase protein in response to oxidative stress
-
Hayakawa, H.; Sekiguchi, M. Human polynucleotide phosphorylase protein in response to oxidative stress. Biochemistry (Mosc). 2006, 45, 6749-6755.
-
(2006)
Biochemistry (Mosc)
, vol.45
, pp. 6749-6755
-
-
Hayakawa, H.1
Sekiguchi, M.2
-
118
-
-
0037159257
-
Binding capacity of human YB-1 protein for RNA containing 8-oxoguanine
-
Hayakawa, H.; Uchiumi, T.; Fukuda, T.; Ashizuka, M.; Kohno, K.; Kuwano, M.; Sekiguchi, M. Binding capacity of human YB-1 protein for RNA containing 8-oxoguanine. Biochemistry (Mosc). 2002, 41, 12739-12744.
-
(2002)
Biochemistry (Mosc)
, vol.41
, pp. 12739-12744
-
-
Hayakawa, H.1
Uchiumi, T.2
Fukuda, T.3
Ashizuka, M.4
Kohno, K.5
Kuwano, M.6
Sekiguchi, M.7
-
119
-
-
34247360454
-
Probing the mRNA processing body using protein macroarrays and "autoantigenomics
-
Yang, W. H.; Bloch, D. B. Probing the mRNA processing body using protein macroarrays and "autoantigenomics". RNA 2007, 13, 704-712.
-
(2007)
RNA
, vol.13
, pp. 704-712
-
-
Yang, W.H.1
Bloch, D.B.2
|