Ligand-stabilized conformational states of human β 2adrenergic receptor: Insight into G-protein-coupled receptor activation

Biophysical Journal

Volumn 94, Issue 6, 2008, Pages 2027-2042

  Bhattacharya, Supriyo ^a   Hall, Spencer E ^a   Li, Hubert ^a   Vaidehi, Nagarajan ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CATECHOL; DOPAMINE; G PROTEIN COUPLED RECEPTOR; ICI 115881; LIGAND; NORADRENALIN; SALBUTAMOL; UNCLASSIFIED DRUG; CATECHOL DERIVATIVE; ION;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG BINDING; HUMAN; HYDROGEN BOND; LIGAND BINDING; MATHEMATICAL MODEL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN STRUCTURE; ROTATION; BIOLOGICAL MODEL; BIOPHYSICS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER PROGRAM; CONFORMATION; METABOLISM; METHODOLOGY;

ALBUTEROL; BIOPHYSICS; CATECHOLS; DOPAMINE; HUMANS; IONS; LIGANDS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NOREPINEPHRINE; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; SOFTWARE;

EID: 44049086134     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1529/biophysj.107.117648     Document Type: Article

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