Mutations of Tyr326 in the β2-adrenoceptor disrupt multiple receptor functions

European Journal of Pharmacology

Volumn 307, Issue 2, 1996, Pages 243-250

  Gabilondo, Ane M ^a,b   Krasel, Cornelius ^a   Lohse, Martin J ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

2 Adrenoceptor; Adenylyl cyclase; CHO (Chinese hamster ovary) cell; Receptor sequestration

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ADENYLATE CYCLASE; ALANINE; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYANOPINDOLOL I 125; GUANYLYLIMIDODIPHOSPHATE; ISOPRENALINE; PHENYLALANINE; PROPRANOLOL; TYROSINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYANOPINDOLOL; DIAGNOSTIC AGENT; DRUG DERIVATIVE; PINDOLOL; RADIOACTIVE IODINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; MUTATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; ANIMAL; CELL MEMBRANE; DRUG EFFECT; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; METABOLISM; MOLECULAR CLONING; PHYSIOLOGY; PROTEIN BINDING; RADIOASSAY; SITE DIRECTED MUTAGENESIS;

ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ALANINE; ANIMALS; CELL MEMBRANE; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; GENE EXPRESSION; HUMANS; IODINE RADIOISOTOPES; ISOPROTERENOL; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHENYLALANINE; PINDOLOL; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, BETA-2; TRANSFECTION; TYROSINE;

EID: 0030603712     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00247-6     Document Type: Article

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