Dopamine D1 receptor agonist and D2 receptor antagonist effects of the natural product (2)-stepholidine: Molecular modeling and dynamics simulations

Biophysical Journal

Volumn 93, Issue 5, 2007, Pages 1431-1441

  Fu, Wei ^a,b   Shen, Jianhua ^a   Luo, Xiaomin ^a   Zhu, Weiliang ^a,e   Cheng, Jiagao ^a   Yu, Kunqian ^a   Briggs, James M ^c   Jin, Guozhang ^a   Chen, Kaixian ^a   Jiang, Hualiang ^a,d,e  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b FUDAN UNIVERSITY   (China)

^c University of Houston   (United States)

^d EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^e SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR BLOCKING AGENT; NATURAL PRODUCT; STEPHOLIDINE;

ARTICLE; AUTOMATION; CENTRAL NERVOUS SYSTEM DISEASE; CHINESE HERB; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DRUG BINDING SITE; DRUG MECHANISM; DRUG RECEPTOR BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PROTEIN STRUCTURE; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; SIMULATION; STEPHANIA; STRUCTURE ACTIVITY RELATION;

EID: 34548622408     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.106.088500     Document Type: Article

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