-
1
-
-
0026318496
-
Trophic effect of beta-amyloid precursor protein on cerebral cortical neurons in culture
-
Araki W, Kitaguchi N, Tokushima Y, Ishii K, Aratake H, Shimohama S, et al. Trophic effect of beta-amyloid precursor protein on cerebral cortical neurons in culture. Biochem Biophys Res Commun 181 (1): 265-271(1991).
-
(1991)
Biochem Biophys Res Commun
, vol.181
, Issue.1
, pp. 265-271
-
-
Araki, W.1
Kitaguchi, N.2
Tokushima, Y.3
Ishii, K.4
Aratake, H.5
Shimohama, S.6
-
3
-
-
2442557294
-
Brain Cholesterol: Long Secret Life Behind a Barrier
-
Björkhem I and Meaney S. Brain Cholesterol: Long Secret Life Behind a Barrier Arterioscler Thromb Vasc Biol 24: 806-815 (2004).
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 806-815
-
-
Björkhem, I.1
Meaney, S.2
-
4
-
-
0034068864
-
Statins: Effective antiatherosclerotic therapy
-
Blumenthal RS. Statins: effective antiatherosclerotic therapy. Am Heart J 139: 577-583 (2000).
-
(2000)
Am Heart J
, vol.139
, pp. 577-583
-
-
Blumenthal, R.S.1
-
5
-
-
0029671454
-
Cholesterol Modulates α-Secretase Cleavage of Amyloid Precursor Protein
-
Bodovitz S and Klein WL. Cholesterol Modulates α-Secretase Cleavage of Amyloid Precursor Protein. J Biol Chem 271 (8): 4436-4440 (1996).
-
(1996)
J Biol Chem
, vol.271
, Issue.8
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
6
-
-
2542523048
-
Intronic CYP46 polymorphism along with ApoE genotype in sporadic Alzhemier Disease: From risk factors to disease modulators
-
Borroni B, Archetti S, Agosti C, Akkawi N, Brambilla C, Caimi L, et al. Intronic CYP46 polymorphism along with ApoE genotype in sporadic Alzhemier Disease: from risk factors to disease modulators. Neurobiol Aging 25: 747-751 (2004).
-
(2004)
Neurobiol Aging
, vol.25
, pp. 747-751
-
-
Borroni, B.1
Archetti, S.2
Agosti, C.3
Akkawi, N.4
Brambilla, C.5
Caimi, L.6
-
7
-
-
0022549920
-
A receptor-mediated pathway for cholesterol homeostasis
-
Brown MS and Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science 232: 34-47 (1986).
-
(1986)
Science
, vol.232
, pp. 34-47
-
-
Brown, M.S.1
Goldstein, J.L.2
-
8
-
-
4544255297
-
Differential expression of cholesterol hydroxylases in Alzheimer's disease
-
Brown J, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, et al. Differential expression of cholesterol hydroxylases in Alzheimer's disease. J Biol Chem279 (33): 34674-34681 (2004).
-
(2004)
J Biol Chem279
, pp. 34674-34681
-
-
Brown, J.1
Theisler, C.2
Silberman, S.3
Magnuson, D.4
Gottardi-Littell, N.5
Lee, J.M.6
-
9
-
-
3042701772
-
APOE promoter, ACE1 and CYP46 polymorphisms and beta-amyloid in Alzheimer's disease
-
Chalmers KA, Culpan D, Kehoe PG, Wilcock GK, Hughes A, Love S. APOE promoter, ACE1 and CYP46 polymorphisms and beta-amyloid in Alzheimer's disease. Neuroreport 15: 95-98 (2004).
-
(2004)
Neuroreport
, vol.15
, pp. 95-98
-
-
Chalmers, K.A.1
Culpan, D.2
Kehoe, P.G.3
Wilcock, G.K.4
Hughes, A.5
Love, S.6
-
10
-
-
0030823756
-
Acceleration of amyloid fibril formation by specific binding of Aβ (1-40) peptide to ganglioside-containing membrane vesicles
-
Choo-Smith LP, Garzon-Rodriguez W, Glabe CG, Surewicz WK. Acceleration of amyloid fibril formation by specific binding of Aβ (1-40) peptide to ganglioside-containing membrane vesicles. J Biol Chem 272: 22987-22990 (1997).
-
(1997)
J Biol Chem
, vol.272
, pp. 22987-22990
-
-
Choo-Smith, L.P.1
Garzon-Rodriguez, W.2
Glabe, C.G.3
Surewicz, W.K.4
-
11
-
-
0030009126
-
Lack of association of trinucleotide repeat polymorphisms in very-low-density lipoprotein receptor gene with Alzheimer's disease
-
Chung H, Roberts CT, Greenberg S, Rebeck GW, Christie R, Wallace R, et al. Lack of association of trinucleotide repeat polymorphisms in very-low-density lipoprotein receptor gene with Alzheimer's disease. Ann Neurol 39 (6): 800-803 (1996).
-
(1996)
Ann Neurol
, vol.39
, Issue.6
, pp. 800-803
-
-
Chung, H.1
Roberts, C.T.2
Greenberg, S.3
Rebeck, G.W.4
Christie, R.5
Wallace, R.6
-
12
-
-
0027194791
-
-
Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 13;261(5123):921-923 (1993).
-
Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 13;261(5123):921-923 (1993).
-
-
-
-
13
-
-
0033929471
-
Fluvastatin: Effects beyond cholesterol lowering
-
Corsini A. Fluvastatin: effects beyond cholesterol lowering. J Cardiovasc Pharmacol Ther 5:161-175 (2000).
-
(2000)
J Cardiovasc Pharmacol Ther
, vol.5
, pp. 161-175
-
-
Corsini, A.1
-
14
-
-
0035116203
-
Lipid metabolism parameters in patients with Alzheimer's disease and their first degree relatives
-
Czyzewski K, Lalowski MM, Pfeffer A, Barcikowska M. Lipid metabolism parameters in patients with Alzheimer's disease and their first degree relatives. Acta Neurobiol Exp 61: 21-26 (2001).
-
(2001)
Acta Neurobiol Exp
, vol.61
, pp. 21-26
-
-
Czyzewski, K.1
Lalowski, M.M.2
Pfeffer, A.3
Barcikowska, M.4
-
15
-
-
0033393022
-
Low-density lipoprotein-independent effects of statins
-
Davignon J and Laaksonen R. Low-density lipoprotein-independent effects of statins. Curr Opin Lipidol 10: 543-559 (1999).
-
(1999)
Curr Opin Lipidol
, vol.10
, pp. 543-559
-
-
Davignon, J.1
Laaksonen, R.2
-
16
-
-
0030755944
-
A new function for the LDL receptor: Transcytosis of LDL across the blood-brain barrier
-
Dehouck B, Fenart L, Dehouck MP, Pierce A, Torpier G, Cecchelli R. A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier. J Cell Biol 138: 877-889 (1997).
-
(1997)
J Cell Biol
, vol.138
, pp. 877-889
-
-
Dehouck, B.1
Fenart, L.2
Dehouck, M.P.3
Pierce, A.4
Torpier, G.5
Cecchelli, R.6
-
17
-
-
0037008389
-
Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzhemier's disease
-
Desai P, DeKosky ST, Kamboh MI. Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzhemier's disease. Neurosci Lett 328 (1): 9-12 (2002).
-
(2002)
Neurosci Lett
, vol.328
, Issue.1
, pp. 9-12
-
-
Desai, P.1
DeKosky, S.T.2
Kamboh, M.I.3
-
18
-
-
0020557968
-
Cholesterol synthesis in vivo and in vitro in the WHHL rabbit, an animal with defective low density lipoprotein receptors
-
Dietschy JM, Kita T, Suckling KE, Goldstein JL, Brown MS. Cholesterol synthesis in vivo and in vitro in the WHHL rabbit, an animal with defective low density lipoprotein receptors. J Lipid Res 24: 469-480 (1983).
-
(1983)
J Lipid Res
, vol.24
, pp. 469-480
-
-
Dietschy, J.M.1
Kita, T.2
Suckling, K.E.3
Goldstein, J.L.4
Brown, M.S.5
-
20
-
-
0037959071
-
The state of lipid rafts: From model membranes to cells
-
Edidin M. The state of lipid rafts: from model membranes to cells. Annu Rev Biophys Biomol Struct 32: 257-283 (2003).
-
(2003)
Annu Rev Biophys Biomol Struct
, vol.32
, pp. 257-283
-
-
Edidin, M.1
-
21
-
-
0037421206
-
Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
-
Ehehalt R, Keller P, Haass C, Thiele C, Simons K. Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts. J Cell Biol 160: 113-123 (2003).
-
(2003)
J Cell Biol
, vol.160
, pp. 113-123
-
-
Ehehalt, R.1
Keller, P.2
Haass, C.3
Thiele, C.4
Simons, K.5
-
22
-
-
0035142852
-
Cholesterol-dependent modulation of tau phosphorylation in cultured neurons
-
Fan QW, Wei Y, Senda T, Yanagisawa K and Michikawa M. Cholesterol-dependent modulation of tau phosphorylation in cultured neurons. J Neurochem 76: 391-400 (2001).
-
(2001)
J Neurochem
, vol.76
, pp. 391-400
-
-
Fan, Q.W.1
Wei, Y.2
Senda, T.3
Yanagisawa, K.4
Michikawa, M.5
-
23
-
-
0001504829
-
Simvastatin strongly reduces levels of Alzheimer's disease beta - amyloid peptides Aβ 42 and Aβ 40 in vitro and in vivo
-
Fassbender K, Simons M, Bergmann C, Stroick M, Lutjohann D, Keller P, et al. Simvastatin strongly reduces levels of Alzheimer's disease beta - amyloid peptides Aβ 42 and Aβ 40 in vitro and in vivo. Proc Natl Acad Sci USA 98 (10): 5856-5861 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.10
, pp. 5856-5861
-
-
Fassbender, K.1
Simons, M.2
Bergmann, C.3
Stroick, M.4
Lutjohann, D.5
Keller, P.6
-
24
-
-
0032937469
-
Effects of apolipoprotein E genotype on blood lipid composition and membrane platelet fluidity in Alzheimer Disease
-
Fernandes MA. Effects of apolipoprotein E genotype on blood lipid composition and membrane platelet fluidity in Alzheimer Disease. Biochym Biophys Acta 1454: 89-96 (1999).
-
(1999)
Biochym Biophys Acta
, vol.1454
, pp. 89-96
-
-
Fernandes, M.A.1
-
25
-
-
0033554880
-
Apolipoprotein E-epsilon4 genotype predicts a poor outcome in survivors of traumatic brain injury
-
Friedman G, Froom P, Sazbon L, Grinblatt I, Shochina M, Tsenter J, et al. Apolipoprotein E-epsilon4 genotype predicts a poor outcome in survivors of traumatic brain injury. Neurology 52:244-8 (1999).
-
(1999)
Neurology
, vol.52
, pp. 244-248
-
-
Friedman, G.1
Froom, P.2
Sazbon, L.3
Grinblatt, I.4
Shochina, M.5
Tsenter, J.6
-
26
-
-
0037010287
-
Amyloid-protein affects cholesterol metabolism in cultured neurons: Implications for pivotal role of cholesterol in the amyloid cascade
-
Gong JS, Sawamura N, Zou K, Sakai J, Yanagisawa K and Michikawa M. Amyloid-protein affects cholesterol metabolism in cultured neurons: Implications for pivotal role of cholesterol in the amyloid cascade. J Neurosci Res 70: 438- 446 (2002).
-
(2002)
J Neurosci Res
, vol.70
, pp. 438-446
-
-
Gong, J.S.1
Sawamura, N.2
Zou, K.3
Sakai, J.4
Yanagisawa, K.5
Michikawa, M.6
-
27
-
-
0025946238
-
-
Goodrum JF. Cholesterol from degenerating nerve myelin becomes associated with lipoproteins containing apolipoprotein Eur J Neurochem 56:2082-2086 (1991).
-
Goodrum JF. Cholesterol from degenerating nerve myelin becomes associated with lipoproteins containing apolipoprotein Eur J Neurochem 56:2082-2086 (1991).
-
-
-
-
28
-
-
0141814636
-
Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice
-
Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, et al. Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice. Proc Natl Acad Sci USA 100 (19): 10966-10971 (2003).
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.19
, pp. 10966-10971
-
-
Harris, F.M.1
Brecht, W.J.2
Xu, Q.3
Tesseur, I.4
Kekonius, L.5
Wyss-Coray, T.6
-
29
-
-
0034305790
-
Apolipoprotein E receptors: Linking brain development and Alzheimer's Disease
-
Herz J, Beffert U. Apolipoprotein E receptors: linking brain development and Alzheimer's Disease. Nat Rev Neurosci 1:51-58 (2000).
-
(2000)
Nat Rev Neurosci
, vol.1
, pp. 51-58
-
-
Herz, J.1
Beffert, U.2
-
30
-
-
0028177562
-
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
-
Howland DS, Trusko SP, Savage MJ, Reaume AG, Lang DM, Hirsch JD. Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp Neurol 126(1): 88-94 (1994).
-
(1994)
Exp Neurol
, vol.126
, Issue.1
, pp. 88-94
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
-
31
-
-
0035902514
-
Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons
-
Huang Y, Liu XQ, Wyss-Coray T, Brecht WJ, Sanan DA, Mahley RW. Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons. Proc Natl Acad Sci USA 98 (15): 8838-8843 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.15
, pp. 8838-8843
-
-
Huang, Y.1
Liu, X.Q.2
Wyss-Coray, T.3
Brecht, W.J.4
Sanan, D.A.5
Mahley, R.W.6
-
32
-
-
5144227934
-
The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease
-
Hutter-Paier B, Huttunen HJ, Puglielli L, Eckman CB, Kim DY, Hofmeister A, et al. The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease. Neuron 44 (2): 227-238 (2004).
-
(2004)
Neuron
, vol.44
, Issue.2
, pp. 227-238
-
-
Hutter-Paier, B.1
Huttunen, H.J.2
Puglielli, L.3
Eckman, C.B.4
Kim, D.Y.5
Hofmeister, A.6
-
33
-
-
2942740962
-
Variants of CYP46A1 may interact with age and ApoE to influence CSF Aβ42 levels in Alzheimer's disease
-
Johannsson A, Katzov H, Zetterberg H, Feuk L, Johansson B, Bogdanovic N, et al. Variants of CYP46A1 may interact with age and ApoE to influence CSF Aβ42 levels in Alzheimer's disease. Hum Genet 114: 581-587 (2004).
-
(2004)
Hum Genet
, vol.114
, pp. 581-587
-
-
Johannsson, A.1
Katzov, H.2
Zetterberg, H.3
Feuk, L.4
Johansson, B.5
Bogdanovic, N.6
-
34
-
-
23944523570
-
ApoE -491A/T promoter polymorphism is not an independent risk factor, but associated with the epsilon4 allele in Hungarian Alzheimer's dementia population
-
Juhasz A, Palotas A, Janka Z, Rimanoczy A, Palotas M, Bodi N, et al. ApoE -491A/T promoter polymorphism is not an independent risk factor, but associated with the epsilon4 allele in Hungarian Alzheimer's dementia population. Neurochem Res 30 (5): 591-596 (2005).
-
(2005)
Neurochem Res
, vol.30
, Issue.5
, pp. 591-596
-
-
Juhasz, A.1
Palotas, A.2
Janka, Z.3
Rimanoczy, A.4
Palotas, M.5
Bodi, N.6
-
35
-
-
2542422805
-
Exclusion of CYP46 and APOM as candidate genes for Alzheimer's disease in a French population
-
Kabara A, Payet N, Cottel D, Frigard B, Amouyel P, Lambert JC. Exclusion of CYP46 and APOM as candidate genes for Alzheimer's disease in a French population. Neurosci Lett 363: 139-143 (2004).
-
(2004)
Neurosci Lett
, vol.363
, pp. 139-143
-
-
Kabara, A.1
Payet, N.2
Cottel, D.3
Frigard, B.4
Amouyel, P.5
Lambert, J.C.6
-
36
-
-
0035816709
-
Cholesterol- dependent formation of GM1 ganglioside bound amyloid β-protein, an endogenous seed for Alzheimer amyloid
-
Kakio A, Nishimoto SI, Yanagisawa K, Kozutsumi Y, Matsuzaki K. Cholesterol- dependent formation of GM1 ganglioside bound amyloid β-protein, an endogenous seed for Alzheimer amyloid. J Biol Chem 276: 24985-24990 (2001).
-
(2001)
J Biol Chem
, vol.276
, pp. 24985-24990
-
-
Kakio, A.1
Nishimoto, S.I.2
Yanagisawa, K.3
Kozutsumi, Y.4
Matsuzaki, K.5
-
37
-
-
11144357626
-
Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism
-
Katzov H, Chalmers K, Palmgren J, Andreasen N, Johannson B, Cairns NJ, et al. Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism. Hum Mutat 23 (4): 358-367 (2004).
-
(2004)
Hum Mutat
, vol.23
, Issue.4
, pp. 358-367
-
-
Katzov, H.1
Chalmers, K.2
Palmgren, J.3
Andreasen, N.4
Johannson, B.5
Cairns, N.J.6
-
38
-
-
0344011137
-
Cognitive impairment associated with atorvastatin and simvastatin
-
King DS, Wilburn AJ, Wofford MR, Harrell TK, Lindley BJ, Jones DW. Cognitive impairment associated with atorvastatin and simvastatin. Pharmacotherapy 23 (12): 1663-1667 (2003).
-
(2003)
Pharmacotherapy
, vol.23
, Issue.12
, pp. 1663-1667
-
-
King, D.S.1
Wilburn, A.J.2
Wofford, M.R.3
Harrell, T.K.4
Lindley, B.J.5
Jones, D.W.6
-
39
-
-
0037031125
-
Apolipoprotein E e4 allele, elevated midlife total cholesterol and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer's disease
-
Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, et al. Apolipoprotein E e4 allele, elevated midlife total cholesterol and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer's disease. Ann Intern Med 137: 149-155 (2002).
-
(2002)
Ann Intern Med
, vol.137
, pp. 149-155
-
-
Kivipelto, M.1
Helkala, E.L.2
Laakso, M.P.3
Hänninen, T.4
Hallikainen, M.5
Alhainen, K.6
-
40
-
-
0028204944
-
Plasma lipids and cholesterol esterification in Alzheimer's Disease
-
Knebl J. Plasma lipids and cholesterol esterification in Alzheimer's Disease. Mech Ageing Dev 73: 69-77 (1994).
-
(1994)
Mech Ageing Dev
, vol.73
, pp. 69-77
-
-
Knebl, J.1
-
41
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10
-
Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10. Proc Natl Acad Sci USA 98: 5815-5820 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5815-5820
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
Marz, W.4
Fahrenholz, F.5
-
42
-
-
0036384169
-
Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease
-
Kolsch H, Lütjohann D, Ludwig M, Schulte A, Ptok U, Jessen F, et al. Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease. Mol Psychiatry 7(8): 899-902 (2002).
-
(2002)
Mol Psychiatry
, vol.7
, Issue.8
, pp. 899-902
-
-
Kolsch, H.1
Lütjohann, D.2
Ludwig, M.3
Schulte, A.4
Ptok, U.5
Jessen, F.6
-
43
-
-
0031970198
-
Nascent astrocyte particles differ from lipoproteins in CSF
-
LaDu MJ, Gilligan SM, Lukens JR, Cabana VG, Reardon CA, Van Eldik LJ, et al. Nascent astrocyte particles differ from lipoproteins in CSF. J Neurochem 70: 2070-2081 (1998).
-
(1998)
J Neurochem
, vol.70
, pp. 2070-2081
-
-
LaDu, M.J.1
Gilligan, S.M.2
Lukens, J.R.3
Cabana, V.G.4
Reardon, C.A.5
Van Eldik, L.J.6
-
44
-
-
0031911596
-
A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease
-
Lambert JC, Pasquier F, Cottel D, Frigard B, Amouyel P, Chartier-Harlin MC. A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease. Hum Mol Genet 7 (3): 533-540 (1998).
-
(1998)
Hum Mol Genet
, vol.7
, Issue.3
, pp. 533-540
-
-
Lambert, J.C.1
Pasquier, F.2
Cottel, D.3
Frigard, B.4
Amouyel, P.5
Chartier-Harlin, M.C.6
-
45
-
-
0034013067
-
-
Lambert JC, Brousseau1 T, Defosse1 V, Evans A, Arveiler D, Ruidavets JB, et al. Independent association of an APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations - the ECTIM Study. Hum Mol Genet 9 (1): 57-61 (2000).
-
Lambert JC, Brousseau1 T, Defosse1 V, Evans A, Arveiler D, Ruidavets JB, et al. Independent association of an APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations - the ECTIM Study. Hum Mol Genet 9 (1): 57-61 (2000).
-
-
-
-
46
-
-
0031746979
-
A detergent- insoluble membrane compartment contains Aβ in vivo
-
Lee SJ, Liyanage U, Bickel PE, Xia W, Lansbury PT and Kosik KS. A detergent- insoluble membrane compartment contains Aβ in vivo. Nat Med 4: 730-734 (1998).
-
(1998)
Nat Med
, vol.4
, pp. 730-734
-
-
Lee, S.J.1
Liyanage, U.2
Bickel, P.E.3
Xia, W.4
Lansbury, P.T.5
Kosik, K.S.6
-
47
-
-
0036128358
-
Reduction of Plasma 24S-Hydroxycholesterol (Cerebrosterol) Levels Using High-Dosage Simvastatin in Patients With Hypercholesterolemia: Evidence That Simvastatin Affects Cholesterol Metabolism in the Human Brain
-
Locatelli S, Lütjohann D, Schmidt HHJ, Otto C, Beisiegel U, Bergmann K. Reduction of Plasma 24S-Hydroxycholesterol (Cerebrosterol) Levels Using High-Dosage Simvastatin in Patients With Hypercholesterolemia: Evidence That Simvastatin Affects Cholesterol Metabolism in the Human Brain. Arch Neurol 59:213-216 (2002).
-
(2002)
Arch Neurol
, vol.59
, pp. 213-216
-
-
Locatelli, S.1
Lütjohann, D.2
Schmidt, H.H.J.3
Otto, C.4
Beisiegel, U.5
Bergmann, K.6
-
48
-
-
0033594903
-
cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
-
Lund EG, Guileyardo JM and Russell DW. cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain. Proc Natl Acad Sci USA 96: 7238-7243 (1999).
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7238-7243
-
-
Lund, E.G.1
Guileyardo, J.M.2
Russell, D.W.3
-
49
-
-
0029879111
-
Membrane stiffness and Channel function
-
Lundbaek JA, Birn P, Girshman J, Hansen AJ, Andersen OS. Membrane stiffness and Channel function. Biochem 35: 3825-3830 (1996).
-
(1996)
Biochem
, vol.35
, pp. 3825-3830
-
-
Lundbaek, J.A.1
Birn, P.2
Girshman, J.3
Hansen, A.J.4
Andersen, O.S.5
-
50
-
-
0343775806
-
Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients
-
Lütjohann D, Papassotiropoulos A, Björkhemd I, Locatelli S, Bagli M, Oehring RD, et al. Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. J Lipid Res 41: 195-198 (2000).
-
(2000)
J Lipid Res
, vol.41
, pp. 195-198
-
-
Lütjohann, D.1
Papassotiropoulos, A.2
Björkhemd, I.3
Locatelli, S.4
Bagli, M.5
Oehring, R.D.6
-
51
-
-
0029835410
-
Cholesterol homeostasis in human brain: Evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation
-
Lütjohann D, Breuer O, Ahlborg G, Nennesmo I, Siden A, Diczfalusy U, et al . Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation. Proc Natl Acad Sci USA 93: 9799-9804 (1996).
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9799-9804
-
-
Lütjohann, D.1
Breuer, O.2
Ahlborg, G.3
Nennesmo, I.4
Siden, A.5
Diczfalusy, U.6
-
52
-
-
19944429282
-
-
Mace S, Cousin E, Ricard S, Genin E, Spanakis E, Lafargue-Soubigou C, et al. ABCA2 is a strong genetic risk factor for earlyonset Alzhemier's disease. Neurobiol Dis 18: 119-125 (2005).
-
Mace S, Cousin E, Ricard S, Genin E, Spanakis E, Lafargue-Soubigou C, et al. ABCA2 is a strong genetic risk factor for earlyonset Alzhemier's disease. Neurobiol Dis 18: 119-125 (2005).
-
-
-
-
53
-
-
0024299370
-
-
Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240: 622-630 (1988).
-
Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240: 622-630 (1988).
-
-
-
-
54
-
-
0033616779
-
Interactions of amyloid β-peptide (1-40) with ganglioside containing membranes
-
Matsuzaki K and Horikiri C. Interactions of amyloid β-peptide (1-40) with ganglioside containing membranes. Biochemistry 38: 4137-4142 (1999).
-
(1999)
Biochemistry
, vol.38
, pp. 4137-4142
-
-
Matsuzaki, K.1
Horikiri, C.2
-
55
-
-
0035834416
-
CNS synaptogenesis promoted by glia-derived cholesterol
-
Mauch DH, Nagler K, Schumacher S, Goritz C, Muller EC, Otto A, et al. CNS synaptogenesis promoted by glia-derived cholesterol. Science 294: 1354-1357 (2001).
-
(2001)
Science
, vol.294
, pp. 1354-1357
-
-
Mauch, D.H.1
Nagler, K.2
Schumacher, S.3
Goritz, C.4
Muller, E.C.5
Otto, A.6
-
56
-
-
0033968648
-
Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture
-
Michikawa M, Fan QW, Isobe I and Yanagisawa K. Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture. J Neurochem 74 (3): 1008-1016 (2000).
-
(2000)
J Neurochem
, vol.74
, Issue.3
, pp. 1008-1016
-
-
Michikawa, M.1
Fan, Q.W.2
Isobe, I.3
Yanagisawa, K.4
-
57
-
-
0035884905
-
A novel action of Alzheimer's amyloid b-protein (Ab): Oligomeric Ab promotes lipid release
-
Michikawa M, Gong JS, Fan QW, Sawamura N and Yanagisawa K. A novel action of Alzheimer's amyloid b-protein (Ab): oligomeric Ab promotes lipid release. J Neurosci 21(18): 7226-7235 (2001).
-
(2001)
J Neurosci
, vol.21
, Issue.18
, pp. 7226-7235
-
-
Michikawa, M.1
Gong, J.S.2
Fan, Q.W.3
Sawamura, N.4
Yanagisawa, K.5
-
58
-
-
0037319158
-
The Role of Cholesterol in Pathogenesis of Alzheimer's Disease
-
Michikawa M. The Role of Cholesterol in Pathogenesis of Alzheimer's Disease. Mol Neurobiol 27: 1-12 (2003).
-
(2003)
Mol Neurobiol
, vol.27
, pp. 1-12
-
-
Michikawa, M.1
-
59
-
-
22144435582
-
Neurodegenerative Disorders and Cholesterol
-
Michikawa M. Neurodegenerative Disorders and Cholesterol. Curr Alzheim Res 1(4): 271-275 (2004).
-
(2004)
Curr Alzheim Res
, vol.1
, Issue.4
, pp. 271-275
-
-
Michikawa, M.1
-
60
-
-
18844457544
-
Elevated total cholesterol levels in late-life associated with a reduced risk of dementia
-
Mielke MM, Zandi PP, Sjogren M, Gustafson D, Ostling S, Steen B, et al. Elevated total cholesterol levels in late-life associated with a reduced risk of dementia. Neurology 64: 1689-1695 (2005).
-
(2005)
Neurology
, vol.64
, pp. 1689-1695
-
-
Mielke, M.M.1
Zandi, P.P.2
Sjogren, M.3
Gustafson, D.4
Ostling, S.5
Steen, B.6
-
61
-
-
0032960305
-
Regulation of Amyloid Precursor Protein Cleavage
-
Mills J, Reiner PB. Regulation of Amyloid Precursor Protein Cleavage. J Neurochem 72: 443-460 (1999).
-
(1999)
J Neurochem
, vol.72
, pp. 443-460
-
-
Mills, J.1
Reiner, P.B.2
-
62
-
-
0037265694
-
The synaptophysin/synaptobrevin interaction critically depends on the cholesterol content
-
Mitter D, Hinz B, Reisinger C, Hollmann S, Yelamanchili SV, Treiber-Held S, et al. The synaptophysin/synaptobrevin interaction critically depends on the cholesterol content. J Neurochem 84: 35-42 (2003).
-
(2003)
J Neurochem
, vol.84
, pp. 35-42
-
-
Mitter, D.1
Hinz, B.2
Reisinger, C.3
Hollmann, S.4
Yelamanchili, S.V.5
Treiber-Held, S.6
-
63
-
-
0034928074
-
Cholesterol accumulates in senile plaques of Alzheimer Disease patients and in transgenic APP (SW) mice
-
Mori T. Cholesterol accumulates in senile plaques of Alzheimer Disease patients and in transgenic APP (SW) mice. J Neuropathol Exp Neurol 60: 778-785 (2001).
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 778-785
-
-
Mori, T.1
-
64
-
-
0032405857
-
Reduced levels of cholesterol, phospholipids, and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4
-
Mulder M, Ravid R, Swaab DF, de Kloet ER, Haasdijk ED, Julk J, et al. Reduced levels of cholesterol, phospholipids, and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4. Alzheim Dis Assoc Disords 12: 198-203 (1998).
-
(1998)
Alzheim Dis Assoc Disords
, vol.12
, pp. 198-203
-
-
Mulder, M.1
Ravid, R.2
Swaab, D.F.3
de Kloet, E.R.4
Haasdijk, E.D.5
Julk, J.6
-
65
-
-
23944452590
-
No genetic association between ATP binding cassette proteins and Japanese sporadic Alzheimer's disease
-
Ohkubo T, Shibata N, Ohnuma T, Higashi S, Usui C, Ueki A, et al. No genetic association between ATP binding cassette proteins and Japanese sporadic Alzheimer's disease. Dement Geriatr Cogn Disord 20: 95-98 (2005).
-
(2005)
Dement Geriatr Cogn Disord
, vol.20
, pp. 95-98
-
-
Ohkubo, T.1
Shibata, N.2
Ohnuma, T.3
Higashi, S.4
Usui, C.5
Ueki, A.6
-
66
-
-
9444244971
-
Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease
-
Okuizumi K, Onodera O, Seki K, Tanaka H, Namba Y, Ikeda K, et al. Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease. Ann Neurol 40 (2): 251-254 (1996).
-
(1996)
Ann Neurol
, vol.40
, Issue.2
, pp. 251-254
-
-
Okuizumi, K.1
Onodera, O.2
Seki, K.3
Tanaka, H.4
Namba, Y.5
Ikeda, K.6
-
67
-
-
0037227538
-
Increased brain β-amyloid load, phosphorylated tau and risk of Alzheimer disease associated with an intronic CYP46 polymorphism
-
Papassotiropoulos A, Streffer JR, Tsolaki M, Schmid S, Thal D, Nicosia F, et al. Increased brain β-amyloid load, phosphorylated tau and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. Arch Neurol 60: 29-35 (2003).
-
(2003)
Arch Neurol
, vol.60
, pp. 29-35
-
-
Papassotiropoulos, A.1
Streffer, J.R.2
Tsolaki, M.3
Schmid, S.4
Thal, D.5
Nicosia, F.6
-
68
-
-
0037230328
-
Outsourcing in the brain: Do neurons depend on cholesterol delivery by astrocytes?
-
Pfrieger FW. Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes? Bioessays 25: 72-78 (2003).
-
(2003)
Bioessays
, vol.25
, pp. 72-78
-
-
Pfrieger, F.W.1
-
69
-
-
0034515763
-
E and Alzheimer's Disease A Role in Amyloid Catabolism
-
Poirier J. Apolipoprotein E and Alzheimer's Disease A Role in Amyloid Catabolism. Ann NY Acad Sci 924: 81-85 (2000).
-
(2000)
Ann NY Acad Sci
, vol.924
, pp. 81-85
-
-
Apolipoprotein, P.J.1
-
70
-
-
11444251445
-
E, cholesterol transport and synthesis in sporadic Alzheimer's disease
-
Poirier J. Apolipoprotein E, cholesterol transport and synthesis in sporadic Alzheimer's disease. Neurobiol Aging 26 (3): 355-61 (2005).
-
(2005)
Neurobiol Aging
, vol.26
, Issue.3
, pp. 355-361
-
-
Apolipoprotein, P.J.1
-
71
-
-
0030661651
-
Role of lipoproteins in the delivery of lipids to axons during axonal regeneration
-
Posse de Chaves E, Rusiñol A, Campenot RB, Vance DE, Vance JE. Role of lipoproteins in the delivery of lipids to axons during axonal regeneration. J Biol Chem 272: 30766-30773 (1997).
-
(1997)
J Biol Chem
, vol.272
, pp. 30766-30773
-
-
Posse de Chaves, E.1
Rusiñol, A.2
Campenot, R.B.3
Vance, D.E.4
Vance, J.E.5
-
72
-
-
0034795651
-
Acyl-coenzyme A: Cholesterol acyl transferase modulates the generation of the amyloid beta-peptide
-
Puglielli L, Konopka G, Pack-Chung E, Ingano LA, Berezovska O, Hyman BT. Acyl-coenzyme A: cholesterol acyl transferase modulates the generation of the amyloid beta-peptide. Nat Cell Biol 3: 905-912 (2001).
-
(2001)
Nat Cell Biol
, vol.3
, pp. 905-912
-
-
Puglielli, L.1
Konopka, G.2
Pack-Chung, E.3
Ingano, L.A.4
Berezovska, O.5
Hyman, B.T.6
-
74
-
-
17644429206
-
Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content
-
Racchi M, Baetta R, Salvietti N, Ianna P, Franceschini G, Paoletti R, et al. Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content. Biochem J 322: 893-898 (1997).
-
(1997)
Biochem J
, vol.322
, pp. 893-898
-
-
Racchi, M.1
Baetta, R.2
Salvietti, N.3
Ianna, P.4
Franceschini, G.5
Paoletti, R.6
-
75
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
Refolo LM, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, et al. Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis 7: 321-331 (2000).
-
(2000)
Neurobiol Dis
, vol.7
, pp. 321-331
-
-
Refolo, L.M.1
Malester, B.2
LaFrancois, J.3
Bryant-Thomas, T.4
Wang, R.5
Tint, G.S.6
-
76
-
-
0035160066
-
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease
-
Refolo LM, Pappolla MA, LaFrancois J, Malester B, Schmidt SD, Thomas-Bryant T, et al. A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease. Neurobiol Dis 8: 890-899 (2001).
-
(2001)
Neurobiol Dis
, vol.8
, pp. 890-899
-
-
Refolo, L.M.1
Pappolla, M.A.2
LaFrancois, J.3
Malester, B.4
Schmidt, S.D.5
Thomas-Bryant, T.6
-
77
-
-
2442489033
-
Relation of plasma lipids to Alzheimer disease and vascular dementia
-
Reitz C, Tang MX, Luchsinger J, Mayeux R. Relation of plasma lipids to Alzheimer disease and vascular dementia. Arch Neurol 61: 705-714 (2004).
-
(2004)
Arch Neurol
, vol.61
, pp. 705-714
-
-
Reitz, C.1
Tang, M.X.2
Luchsinger, J.3
Mayeux, R.4
-
78
-
-
4644224016
-
Association analysis of genes involved in cholesterol metabolism located within the linkage region on chromsome 10 and Alzheimer's disease
-
Riemenschneider M, Mahmoodzadeh S, Eisele T, Klopp N, Schwarz S, Wagenpfeil S, et al. Association analysis of genes involved in cholesterol metabolism located within the linkage region on chromsome 10 and Alzheimer's disease. Neurobiol Aging 25(10): 1305-1308 (2004).
-
(2004)
Neurobiol Aging
, vol.25
, Issue.10
, pp. 1305-1308
-
-
Riemenschneider, M.1
Mahmoodzadeh, S.2
Eisele, T.3
Klopp, N.4
Schwarz, S.5
Wagenpfeil, S.6
-
79
-
-
0033546660
-
APOE genotype, plasma lipids, lipoproteins and AD in community elderly
-
Romas SN, Tang MX, Berglund L, Mayeux R. APOE genotype, plasma lipids, lipoproteins and AD in community elderly. Neurology 53: 517-521 (1999).
-
(1999)
Neurology
, vol.53
, pp. 517-521
-
-
Romas, S.N.1
Tang, M.X.2
Berglund, L.3
Mayeux, R.4
-
80
-
-
0028916836
-
Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging
-
Roth GS, Joseph JA, Mason RP. Membrane alterations as causes of impaired signal transduction in Alzheimer's disease and aging. Trends Neurosci 18: 203-206 (1995).
-
(1995)
Trends Neurosci
, vol.18
, pp. 203-206
-
-
Roth, G.S.1
Joseph, J.A.2
Mason, R.P.3
-
81
-
-
0036523031
-
Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells
-
Runz H, Rietdorf J, Tomic I, de Bernard M, Beyreuther K, Pepperkok R, et al. Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells. J Neurosci 22: 1679-1689 (2002).
-
(2002)
J Neurosci
, vol.22
, pp. 1679-1689
-
-
Runz, H.1
Rietdorf, J.2
Tomic, I.3
de Bernard, M.4
Beyreuther, K.5
Pepperkok, R.6
-
82
-
-
0035124734
-
-
Scacchi R, Gambina G, Martini MC, Ruggeri M, Ferrari G, Sivestri M, et al. Polymorphisms of the apolipoprotein E gene regulatory region and of the LDL receptor gene in Late-onset Alzheimer's disease in relation to the plasma lipidic pattern. Dement Geriatr Cogn Disord 12: 63-68 (2001).
-
Scacchi R, Gambina G, Martini MC, Ruggeri M, Ferrari G, Sivestri M, et al. Polymorphisms of the apolipoprotein E gene regulatory region and of the LDL receptor gene in Late-onset Alzheimer's disease in relation to the plasma lipidic pattern. Dement Geriatr Cogn Disord 12: 63-68 (2001).
-
-
-
-
83
-
-
0024318406
-
Amyloid beta protein precursor is a mitogen
-
Schubert D, Cole G, Saitoh T, Oltersdorf T. Amyloid beta protein precursor is a mitogen. Biochem Biophys Res Commun 162(1): 83-88 (1989).
-
(1989)
Biochem Biophys Res Commun
, vol.162
, Issue.1
, pp. 83-88
-
-
Schubert, D.1
Cole, G.2
Saitoh, T.3
Oltersdorf, T.4
-
84
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe DJ. The molecular pathology of Alzheimer's disease. Neuron 6: 487-498 (1991).
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
85
-
-
28444470503
-
Assocaition studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease
-
Shibata N, Kawarai T, Lee JL, Lee HS, Shibata E, Sato C, et al. Assocaition studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease. Neurosci Lett 391: 142-146. (2006).
-
(2006)
Neurosci Lett
, vol.391
, pp. 142-146
-
-
Shibata, N.1
Kawarai, T.2
Lee, J.L.3
Lee, H.S.4
Shibata, E.5
Sato, C.6
-
86
-
-
1442285095
-
Proteolytic cascade in the amyloidogenesis of AD
-
Sidera C, Parson R, Austen D. Proteolytic cascade in the amyloidogenesis of AD. Biochem Soc Trans 32: 33-36 (2004).
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 33-36
-
-
Sidera, C.1
Parson, R.2
Austen, D.3
-
87
-
-
0032568552
-
Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons
-
Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K. Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons. Proc Natl Acad Sci USA 95: 6460-6464 (1998).
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
88
-
-
0036714243
-
Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial
-
Simons M, Schwarzler F, Lutjohann D, von Bergmann K, Beyreuther K, Dichgans J, et al. Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial. Ann Neurol 52(3): 346-350 (2002).
-
(2002)
Ann Neurol
, vol.52
, Issue.3
, pp. 346-350
-
-
Simons, M.1
Schwarzler, F.2
Lutjohann, D.3
von Bergmann, K.4
Beyreuther, K.5
Dichgans, J.6
-
89
-
-
0028177562
-
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
-
Sparks DL, Scheff SW, Hunsaker JC, Liu H, Landers T, Gross DR. Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp Neurol 126: 88-94 (1994).
-
(1994)
Exp Neurol
, vol.126
, pp. 88-94
-
-
Sparks, D.L.1
Scheff, S.W.2
Hunsaker, J.C.3
Liu, H.4
Landers, T.5
Gross, D.R.6
-
90
-
-
0029888944
-
Intraneuronal beta-amyloid immunoreactivity in the CNS
-
Sparks DL. Intraneuronal beta-amyloid immunoreactivity in the CNS. Neurobiol Aging 17: 291-9 (1996).
-
(1996)
Neurobiol Aging
, vol.17
, pp. 291-299
-
-
Sparks, D.L.1
-
91
-
-
0034663175
-
Link between heart disease, cholesterol and Alzheimer's Disease
-
Sparks DL, Martin TA, Gross DR, Hunsaker JC. Link between heart disease, cholesterol and Alzheimer's Disease. Microsc Res Tech 50: 287-290 (2000).
-
(2000)
Microsc Res Tech
, vol.50
, pp. 287-290
-
-
Sparks, D.L.1
Martin, T.A.2
Gross, D.R.3
Hunsaker, J.C.4
-
93
-
-
0037992873
-
Plasma total cholesterol level as a risk factor for Alzheimer disease: The Framingham Study
-
Tan ZS, Seshadri S, Beiser A, Wilson PW, Kiel DP, Tocco M, et al. Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study. Arch Intern Med 163(9): 1053-7 (2003).
-
(2003)
Arch Intern Med
, vol.163
, Issue.9
, pp. 1053-1057
-
-
Tan, Z.S.1
Seshadri, S.2
Beiser, A.3
Wilson, P.W.4
Kiel, D.P.5
Tocco, M.6
-
94
-
-
0037434101
-
Temporal and spatial profiles of ABCA2-expressing oligodendrocytes in the developing rat brain
-
Tanaka Y, Yamada K, Zhou CJ, Ban N, Shioda S, Inagaki N. Temporal and spatial profiles of ABCA2-expressing oligodendrocytes in the developing rat brain. J Comp Neurol 455: 353-367 (2003).
-
(2003)
J Comp Neurol
, vol.455
, pp. 353-367
-
-
Tanaka, Y.1
Yamada, K.2
Zhou, C.J.3
Ban, N.4
Shioda, S.5
Inagaki, N.6
-
95
-
-
33745514065
-
-
Thelen KM, Falkai P, Bayer TA, Lutjohann D. Cholesterol synthesis rate in human hippocampus declines with aging. Neurosci Lett. 31;403 (1-2): 15-19 (2006).
-
Thelen KM, Falkai P, Bayer TA, Lutjohann D. Cholesterol synthesis rate in human hippocampus declines with aging. Neurosci Lett. 31;403 (1-2): 15-19 (2006).
-
-
-
-
96
-
-
15944389528
-
Cholesterol homeostasis in neurons and glial cells
-
Vance JE, Hayashi H, Karten B. Cholesterol homeostasis in neurons and glial cells. Semin Cell Dev Biol 16: 193-212 (2005).
-
(2005)
Semin Cell Dev Biol
, vol.16
, pp. 193-212
-
-
Vance, J.E.1
Hayashi, H.2
Karten, B.3
-
97
-
-
0000306390
-
Statins do more than just lower cholesterol
-
Vaughan CJ, Murphy MB, Buckley BM. Statins do more than just lower cholesterol. Lancet 348: 1079-1082 (1996).
-
(1996)
Lancet
, vol.348
, pp. 1079-1082
-
-
Vaughan, C.J.1
Murphy, M.B.2
Buckley, B.M.3
-
98
-
-
0038381775
-
Statin-associated memory loss: Analysis of 60 case reports and review of the literature
-
Wagstaff LR, Mitton MW, Arvik BM, Doraiswamy PM. Statin-associated memory loss: analysis of 60 case reports and review of the literature. Pharmacotherapy. 23 (7): 871-880 (2003).
-
(2003)
Pharmacotherapy
, vol.23
, Issue.7
, pp. 871-880
-
-
Wagstaff, L.R.1
Mitton, M.W.2
Arvik, B.M.3
Doraiswamy, P.M.4
-
99
-
-
0034642230
-
Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease
-
Wang JC, Kwon JM, Shah P, Morris JC, Goate A. Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease. Neurology 55:1644-1649 (2000).
-
(2000)
Neurology
, vol.55
, pp. 1644-1649
-
-
Wang, J.C.1
Kwon, J.M.2
Shah, P.3
Morris, J.C.4
Goate, A.5
-
100
-
-
0036180950
-
Cholesterol- dependent γ-secretase activity in buoyant cholesterol-rich membrane microdomains
-
Wahrle S, Das P, Nyborg AC, McLendon C, Shoji M, Kawarabayashi T, et al. Cholesterol- dependent γ-secretase activity in buoyant cholesterol-rich membrane microdomains. Neurobiol Dis 9: 11-23 (2002).
-
(2002)
Neurobiol Dis
, vol.9
, pp. 11-23
-
-
Wahrle, S.1
Das, P.2
Nyborg, A.C.3
McLendon, C.4
Shoji, M.5
Kawarabayashi, T.6
-
101
-
-
4644361588
-
ABCA1 Is Required for Normal Central Nervous System ApoE Levels and for Lipidation of Astrocyte-secreted apoE
-
Wahrle SE, Jiang H, Parsadanian M, Legleiter J, Han X, Fryer JD, et al. ABCA1 Is Required for Normal Central Nervous System ApoE Levels and for Lipidation of Astrocyte-secreted apoE. J Biol Chem 279 (39): 40987-40993 (2004).
-
(2004)
J Biol Chem
, vol.279
, Issue.39
, pp. 40987-40993
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Legleiter, J.4
Han, X.5
Fryer, J.D.6
-
102
-
-
12244255799
-
ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease
-
Wollmer MA, Streffer JR, Lütjohann D, Tsolaki M, Iakovidou V, Hegi T, Pasch T, Jung HH, von Bergman K, Nitsch RM, Hock C, Papassotiropoulos A. ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease. Neurobiol Aging 24: 421-426 (2003).
-
(2003)
Neurobiol Aging
, vol.24
, pp. 421-426
-
-
Wollmer, M.A.1
Streffer, J.R.2
Lütjohann, D.3
Tsolaki, M.4
Iakovidou, V.5
Hegi, T.6
Pasch, T.7
Jung, H.H.8
von Bergman, K.9
Nitsch, R.M.10
Hock, C.11
Papassotiropoulos, A.12
-
103
-
-
10744223627
-
Genetic association of acyl-coenzyme A: Cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load and risk for Alzheimer's disease
-
Wollmer MA, Streffer JR, Tsolaki M, Grimaldi LME, Lütjohan D, Thal D, et al. Genetic association of acyl-coenzyme A: cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load and risk for Alzheimer's disease. Mol Psychiatr 8: 635-8 (2003).
-
(2003)
Mol Psychiatr
, vol.8
, pp. 635-638
-
-
Wollmer, M.A.1
Streffer, J.R.2
Tsolaki, M.3
Grimaldi, L.M.E.4
Lütjohan, D.5
Thal, D.6
-
104
-
-
33745804992
-
Ethnicity dependent genetic association of ABCA2 with sporadic Alzheimer's disease
-
Part B
-
Wollmer MA, Kapaki E, Hersberger M, Muntwyler J, Brunner F, Tsolaki M, et al. Ethnicity dependent genetic association of ABCA2 with sporadic Alzheimer's disease. Am J Med Genet Part B 141B:1-3 (2006).
-
(2006)
Am J Med Genet
, vol.141 B
, pp. 1-3
-
-
Wollmer, M.A.1
Kapaki, E.2
Hersberger, M.3
Muntwyler, J.4
Brunner, F.5
Tsolaki, M.6
-
105
-
-
0033772113
-
Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
-
Wolozin B, Kellman W, Ruosseau P, Celesia GG, Siegel G. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch Neurol 57(10): 1439-43 (2000).
-
(2000)
Arch Neurol
, vol.57
, Issue.10
, pp. 1439-1443
-
-
Wolozin, B.1
Kellman, W.2
Ruosseau, P.3
Celesia, G.G.4
Siegel, G.5
-
106
-
-
22544447688
-
APOE, vascular pathology and the AD brain
-
Yip AG, McKee AC, Green RC, Wells J, Young H, Cupples LA, et al. APOE, vascular pathology and the AD brain. Neurology; 65(2): 259-265 (2005).
-
(2005)
Neurology
, vol.65
, Issue.2
, pp. 259-265
-
-
Yip, A.G.1
McKee, A.C.2
Green, R.C.3
Wells, J.4
Young, H.5
Cupples, L.A.6
-
107
-
-
27244441791
-
Association between acyl-coenzyme A: Cholesterol acyltransferase gene and risk for Alzheimer's disease in Chinese
-
Zhao FG, Wang YH, Yang JF, Ma QL, Tang Z, Dong XM, et al. Association between acyl-coenzyme A: cholesterol acyltransferase gene and risk for Alzheimer's disease in Chinese. Neurosci Lett 388 (1): 17-20 (2005).
-
(2005)
Neurosci Lett
, vol.388
, Issue.1
, pp. 17-20
-
-
Zhao, F.G.1
Wang, Y.H.2
Yang, J.F.3
Ma, Q.L.4
Tang, Z.5
Dong, X.M.6
|