Nascent astrocyte particles differ from lipoproteins in CSF

Journal of Neurochemistry

Volumn 70, Issue 5, 1998, Pages 2070-2081

  LaDu, M J ^a   Gilligan, S M ^a   Lukens, J R ^a   Cabana, V G ^a   Reardon, C A ^a   Van Eldik, L J ^b   Holtzman, D M ^c  

^a UNIVERSITY OF CHICAGO   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Apolipoprotein Al; Apolipoprotein E; Apolipoprotein J; Cholesterol

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; APOLIPOPROTEIN E; CLUSTERIN; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; VERY LOW DENSITY LIPOPROTEIN;

ALZHEIMER DISEASE; ARTICLE; ASTROCYTE; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CHOLESTEROL TRANSPORT; DEGENERATIVE DISEASE; HUMAN; HUMAN CELL; LIPOPROTEIN METABOLISM; PRIORITY JOURNAL;

EID: 0031970198     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70052070.x     Document Type: Article

References (71)

1. Albers J. J., Tollerfson J. H., Wofbauer G., and Albright R. E. (1992) Cholesteryl ester transfer protein in human brain. Int. J. Clin. Lab. Res. 21, 264-266.
2. Alberts M. J., Graffagnino C., McClenny C., DeLong D., Strittmatter W., Saunders A. M., and Roses A. D. (1995) ApoE genotype and survival from intracerebral hemorrhage. Lancet 346, 575.
3. Biere A. L., Ostaszewski B., Stimson E. R., Hyman B. T., Maggio J. E., and Selkoe D. J. (1996) Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma. J. Biol. Chem. 271, 32916-32922.
4. Blennow K., Hesse C., and Freedman P. (1994) Cerebrospinal fluid apolipoprotein E is reduced in Alzheimer's disease. Neuroreport 5, 2534-2536.
5. Boyles J. K., Pitas R. E., Wilson E., Mahley R. W., and Taylor J. M. (1985) Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J. Clin. Invest. 76, 1501-1513.
6. Boyles J. K., Zoellner C. D., Anderson L. J., Kosik L. M., Pitas R. E., Weisgraber K. H., Hui D. Y., Mahley R. W., Gebicke-Haerter P. J., Ignatius M. J., and Shooter E. M. (1989) A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. J. Clin. Invest. 83, 1015-1031.
7. Brown M. S. and Goldstein J. L. (1986) A receptor-mediated pathway for cholesterol homeostasis. Science 232, 34-47.
8. Bu G., Maksymovitch E. A., Nerbonne J. M., and Schwartz A. L. (1994) Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons. J. Biol. Chem. 269, 18521-18528.
9. Cabana V. G., Siegel J. N., and Sabesin S. M. (1989) Effects of the acute phase response on the concentration and density distribution of plasma lipids and apolipoproteins. J. Lipid Res. 30, 39-49.
10. Carlsson J., Armstrong V. W., Reiber H., Felgenhauer K., and Seidel D. (1991) Clinical relevance of the quantification of apolipoprotein E in cerebrospinal fluid. Clin. Chim. Acta 196, 167-176.
11. Castro G. R. and Fielding C. J. (1984) Evidence for the distribution of apolipoprotein E between lipoprotein classes in human normocholesterolemic plasma and for the origin of unassociated apolipoprotein E (Lp-E). J. Lipid Res. 25, 58-67.
12. Chiba H., Mitamura T., Fujisawa S., Ogata A., Aimoto Y., Tashiro K., and Kobayashi K. (1991) Apolipoproteins in rat cerebrospinal fluid: a comparison with plasma lipoprotein metabolism and effect of aging. Neurosci. Lett. 133, 207-210.
13. Choi-Miura N. H., Ihara Y., Fukuchi K., Takeda M., Nakano Y., Tobe T., and Tomita M. (1992) SP-40,40 is a constituent of Alzheimer's amyloid. Acta Neuropathol. 83, 260-264.
14. Christie R. H., Chung H., Rebeck G. W., Strickland D., and Hyman B. T. (1996) Expression of the very low-density lipoprotein receptor (VLDL-r). an apolipoprotein-E receptor, in the central nervous system and in Alzheimer's disease. J. Neuropathol. Exp. Neurol. 55, 491-498.
15. Danik J. R., Chabot J. G., Hassan-Gonzalez D., Suh M., and Quirion R. (1993) Localization of sulfated glycoprotein-2/clusterin mRNA in the rat brain by in situ hybridization. J. Comp. Neurol. 334, 209-227.
16. Davison A. N. (1965) Brain sterol metabolism. Adv. Lipid Res. 3, 171-196.
17. Diedrich J. F., Minnigan H., Carp R. I., Whitaker J. N., Race R., Frey W., and Haase A. T. (1991) Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes. J. Virol. 65, 4759-4768.
18. Elshourbagy N. A., Liao W. S., Mahley R. W., and Taylor J. M. (1985) Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets. Proc. Natl. Acad. Sci. USA 82, 203-207.
19. Evans K. C., Berger E. P., Cho C.-G., Weisgraber K. H., and Lansbury P. T. (1994) Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 92, 763-767.
20. Fainaru M., Glangeaud M. C., and Eisenberg S. (1975) Radioimmunoassay of human high density lipoprotein apoprotein A-I. Biochim. Biophys. Acta 386, 432-443.
21. Fielding C. J. and Fielding P. E. (1995) Molecular physiology of reverse cholesterol transport. J. Lipid Res. 36, 211-228.
22. Fielding C. J., Shore V. G., and Fielding P. E. (1972) A protein cofactor of lecithin:cholesterol acyltransferase. Biochem. Biophys. Res. Commun. 46, 1493-1498.
23. Fielding C. J., Frohlich J., Moser K., and Fielding P. E. (1982) Promotion of sterol efflux and net transport by apolipoprotein E in lecithin:cholesterol acyltransferase deficiency. Metabolism 31, 1023-1028.
24. Forte T. M. and Nordhausen R. W. (1986) Electron microscopy of negatively stained lipoproteins. Methods Enzymol. 128, 442-457.
25. Goslin K. and Banker G. (1991) Rat hippocampal neurons in low-density culture, in Culturing Nerve Cells (G. Banker and K. Goslin, eds), pp. 251-281. MIT Press, Cambridge, Massachusetts.
26. Havel R. J. and Kane J. P. (1989) Introduction: structure and metabolism of plasma lipoproteins, in The Metabolic Basis of Inherited Diseases, pp. 1129-1135. McGraw-Hill, New York.
27. Holtzman D. M., Pitas R. E., Kilbridge J., Nathan B., Mahley R. W., Bu G., and Schwartz A. L. (1995) LRP mediates apolipoprotein E-dependent neurite outgrowth in a CNS-derived neuronal cell line. Proc. Natl. Acad. Sci. USA 92, 9480-9484.
28. Hu J., Castets F., Guevara J. L., and van Eldik L. J. (1996) S100β stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes. J. Biol. Chem. 271, 2543-2547.
29. Jordan J., Galindo M. F., Miller R. J., Reardon C. A., Getz G. S., and LaDu M. J. (1998) Isoform-specific effect of apolipoprotein E on cell survival and amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures. J. Neurosci. 18, 195-204.
30. Kang J., Lemaire H.-G., Unterbeck A., Salbaum J. M., Masters C. L., Grzeschik K.-H., Multhaup G., Beyreuther K., and Müller-Hill B. (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell surface receptor. Nature 325, 733-736.
31. Kim D. H., Iijima H., Goto K., Sakai J., Ishii H., Kim H. J., Suzuki H., Kondo H., Saeki S., and Yamamoto T. (1996) Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain. J. Biol. Chem. 271, 8373-8380.
32. Koudinov A., Matsubara E., Frangione B., and Ghiso J. (1994) The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma. Biochem. Biophys. Res. Commun. 205, 1164-1171.
33. Koudinov A. R., Koudinova N. V., Kumar A., Beavis R. C., and Ghiso J. (1996) Biochemical characterization of Alzheimer's soluble beta protein in human cerebrospinal fluid-association with high density lipoprotein. Biochem. Biophys. Res. Commun. 223, 592-597.
34. Kounnas M. Z., Haudenschild C. C., Strickland D. K., and Argraves W. S. (1994) Immunological localization of glycoprotein 330, low density lipoprotein receptor related protein and 39 kDa receptor associated protein in embryonic mouse tissues. In Vivo 8, 343-351.
35. Krul E. S. and Tang J. (1992) Secretion of apolipoprotein E by an astrocytoma cell line. J. Neurosci. Res. 32, 227-238.
36. Kunitake S. T. and Kane J. P. (1982) Factors affecting the integrity of high density lipoproteins in the ultracentrifuge. J. Lipid Res. 23, 936-940.
37. LaDu M. J., Falduto M. T., Manelli A. M., Reardon C. A., Getz G. S. and Frail D. E. (1994) Isoform-specific binding of apolipoprotein E to β-amyloid. J. Biol. Chem. 269, 23404-23406.
38. LaDu M. J., Pederson T. M., Frail D. E., Reardon C. A., Getz G. S., and Falduto M. T. (1995) Purification of apolipoprotein E attenuates isoform-specific binding to β-amyloid. J. Biol. Chem. 270, 9030-9042.
39. Lehtimaki T., Pirttila T., Mehta P. D., Wisniewski H. M., Frey H., and Nikkari T. (1995) Apolipoprotein E (apoE) polymorphism and its influence on ApoE concentrations in the cerebrospinal fluid in Finnish patients with Alzheimer's disease. Hum. Genet. 95, 39-42.
40. Lendon C. L., Talbot C. J., Craddock N. J., Han S. W., Wragg M., Morris J. C., and Goate A. M. (1997) Genetic association studies between dementia of the Alzheimer's type and three receptors for apolipoprotein E in a Caucasian population. Neurosci. Lett. 222, 187-190.
41. Levinson S. W. and McCarthy K. D. (1991) Culturing Nerve Cells, pp. 309-336. MIT Press, Cambridge, Massachusetts.
42. Linton M. F., Gish R., Hubl S. T., Butler E., Esquivel C., Bry W. I., Boyles J. K., Wardell M. R., and Young S. G. (1991) Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation. J. Clin. Invest. 88, 270-281.
43. Mahley R. W. (1988) Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240, 622-630.
44. Mahley R. W. and Weisgraber K. H. C. R. (1974) Canine lipoproteins and atherosclerosis. Circ. Res. 35, 713-721.
45. May P. C. and Finch C. E. (1992) Sulfated glycoprotein 2: new relationships of this multifunctional protein to neurodegeneration. Trends Neurosci. 15, 391-396.
46. Miyata M. and Smith J. D. (1996) Apolipoprotein E allele specific antioxidant activity and effects on cytotoxicity by oxidative insults and β-amyloid peptides. Nat. Genet. 14, 55-61.
47. Moestrup S. K., Gliemann J., and Pallesen G. (1992) Distribution of the α2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues. Cell Tissue Res. 269, 375-382.
48. Nakai M., Kawamata T., Maeda K., and Tanaka C. (1996) Expression of apoE mRNA in rat microglia. Neurosci. Lett. 211, 41-44.
49. Namba Y., Tomonaga M., Kawasaki H., Otomo E., and Ikeda K. (1991) Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease kuru plaque amyloid in Creutzfeldt-Jacob disease. Brain Res. 541, 163-166.
50. Narita M., Bu G., Holtzman D. M., and Schwartz A. L. (1997) The low density lipoprotein receptor-related protein, a multifunctional apoE receptor, modulates hippocampal neunte development. J. Neurochem. 68, 587-595.
51. Naslund J., Thyberg J., Tjernberg L. O., Wernstedt C., Karlstrom A. R., Bogdanovic N., Gandy S. E., Lannfelt L., Terenius L., and Nordstedt C. (1995) Characterization of stable complexes involving apolipoprotein E and the amyloid β peptide in Alzheimer's disease brain. Neuron 15, 219-228.
52. Nathan B. P., Bellosta S., Sanan D. A., Weisgraber K. H., Mahley R. W., and Pitas R. E. (1994) Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro. Science 264, 850-852.
53. Nicoll J. A. R., Roberts G. W., and Graham D. I. (1995) ApoE E4 allele is associated with deposition of amyloid beta-protein following head injury. Nat. Med. 1, 135-137.
54. Pitas R. E., Boyles J. K., Lee S. H., Foss D., and Mahley R. W. (1987a) Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins. Biochim. Biophys. Acta 917, 148-161.
55. Pitas R. E., Boyles J. K., Lee S. H., Hui D., and Weisgraber K. H. (1987b) Lipoproteins and their receptors in the central nervous system. J. Biol. Chem. 262, 14352-14360.
56. Poirier J. (1994) Apolipoprotein E in animal models of CNS injury and Alzheimer's disease. Trends Neurosci. 17, 525-530.
57. Poirier J., Hess M., May P. C., and Finch C. E. (1991) Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning. Mol. Brain Res. 11, 97-106.
58. Poirier J., Baccichet A., Dea D., and Gauthier S. (1993) Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats. Neuroscience 55, 81-90.
59. Rebeck G. W., Reiter J. S., Strickland D. K., and Hyman B. T. (1993) Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron 11, 575-580.
60. Rifai N., Christenson R. H., Gelman B. B., and Silverman L. M. (1986) Automated determination of apolipoprotein E in cerebrospinal fluid. Clin. Chem. 32, 2207.
61. Roheim P. S., Carey M., Forte T., and Vega G. L. (1979) Apolipoproteins in human cerebrospinal fluid. Proc. Natl. Acad. Sci. USA 76, 4646-4649.
62. Rose K., Goldberg M. P., and Choi D. W. (1993) Cytotoxicity in murine neocortical cell culture, in In Vitro Biological Methods: Methods in Toxicology (Tyson C. A. and Frazier J. M., eds), pp. 46-60. Academic Press, San Diego.
63. Schumaker V. and Puppione D. (1986) Sequential flotation ultracentrifugation. Methods Enzymol. 128, 155-170.
64. Smith K. M., Lawn R. M., and Wilcox J. N. (1990) Cellular localization of apolipoprotein D and lecithin:cholesterol transferase mRNA in rhesus monkey tissues by in-situ hybridization. J. Lipid Res. 31, 995-1004.
65. Stone D. J., Rozovsky I., Morgan T. E., Anderson C. P., Hajian H., and Finch C. E. (1997) Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro. Exp. Neurol. 143, 313-318.
66. Strittmatter W. J. and Roses A. D. (1996) Apolipoprotein E and Alzheimer's disease. Annu. Rev. Neurosci. 19, 53-77.
67. Strittmatter W. J., Saunders A. M., Schmechel D., Pericak-Vance M., Enghild J., Salvesen G. S., and Roses A. D. (1993a) Apolipoprotein E: high avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. USA 90, 1977-1981.
68. Strittmatter W. J., Weisgraber K. H., Huang D. Y., Dong L.-Y., Salvesen G. S., Pericak-Vance M., Schmechel D., Saunders A. M., Goldgaber D., and Roses A. D. (1993b) Binding of human apolipoprotein E to synthetic amyloid β peptide: isoform specific-effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90, 8098-8102.
69. Warden C. H., Langner C. A., Gordon J. I., Taylor B. A., McLean J. W., and Lusis A. J. (1989) Tissue-specific expression, developmental regulation and chromosomal mapping of the lecithin: cholesterol acytransferase gene. J. Biol. Chem. 264, 21573-21581.
70. Wolf B. B., Loppes M. B. S., VandenBerg S. R., and Gonias S. (1992) Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low density lipoprotein receptor-related protein) in human brain. Am. J. Pathol. 141, 37-42.
71. Wood S. J., Chan W., and Wetzel R. (1996) Seeding of Aβ fibril formation is inhibited by all three isotypes of apolipoprotein E. Biochemistry 35, 12623-12628.