Mgmt deficiency alters the in vivo mutational spectrum of tissues exposed to the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

Carcinogenesis

Volumn 29, Issue 4, 2008, Pages 866-874

  Sandercock, Linda E ^a   Hahn, Jennifer N ^b   Li, Li ^b   Luchman, Hartee ^a   Giesbrecht, Jennette L ^a   Peterson, Lisa A ^b   Jirik, Frank R ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; ADENINE; ALKYLATING AGENT; CYTOSINE; DEOXYGUANOSINE; GUANINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; MUTANT PROTEIN; THYMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA ALKYLATION; FEMALE; IN VIVO CULTURE; LUNG CANCER; LUNG CARCINOGENESIS; MALE; MOUSE; MUTAGENIC ACTIVITY; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REPORTER GENE; TISSUE CULTURE; TOBACCO; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; CARCINOGENS; CROSSES, GENETIC; DNA; DNA MODIFICATION METHYLASES; DNA MUTATIONAL ANALYSIS; DNA REPAIR ENZYMES; FEMALE; GENOTYPE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITROSAMINES; POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEINS;

EID: 41949114939     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgn030     Document Type: Article

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