Development of a quantitative liquid chromatography/electrospray mass spectrometric assay for a mutagenic tobacco specific nitrosamine-derived DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]-2′-deoxyguanosine

Chemical Research in Toxicology

Volumn 17, Issue 12, 2004, Pages 1600-1606

  Thomson, Nicole M ^a   Mijal, Renée S ^a   Ziegel, Rebecca ^a   Fleischer, Nancy L ^a   Pegg, Anthony E ^b   Tretyakova, Natalia Y ^a   Peterson, Lisa A ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 BUTANONE; 4 (ACETOXYMETHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; NITROSAMINE; O6 [1,2,2 H3 4 OXO 4 (3 PYRIDYL)BUTYL] 2' DEOXYGUANOSINE; O6 [4 OXO 4 (3 PYRIDYL)BUTYL] 2' DEOXYGUANOSINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA ALKYLATION; DNA ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE DILUTION ASSAY; LIQUID CHROMATOGRAPHY; MOUSE; MUTAGEN TESTING; NONHUMAN; PROTON TRANSPORT; PYRIDYLOXOBUTYL 2' DEOXYGUANOSINE; QUANTITATIVE ANALYSIS; RADIOCHEMISTRY; SENSITIVITY AND SPECIFICITY; TOXICOLOGY;

ANIMALS; CHROMATOGRAPHY, LIQUID; DEOXYGUANOSINE; DNA ADDUCTS; FEMALE; MICE; MUTAGENS; NITROSAMINES; PYRIDINES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TOBACCO;

ANIMALIA; NICOTIANA TABACUM;

EID: 10844279953     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0498298     Document Type: Article

References (44)

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