Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and both the lacI and lacZ gene in transgenic rodents

Nucleic Acids Research

Volumn 25, Issue 1, 1997, Pages 136-137

  Cariello, Neal F ^a   Douglas, George R ^b   Dycaico, Mark J ^c   Gorelick, Nancy J ^d   Provost, G Scott ^c   Soussi, Thierry ^e  

^a GLAXOSMITHKLINE   (United States)

^b HEALTH CANADA   (Canada)

^c Stratagene   (United States)

^d PROCTER AND GAMBLE COMPANY   (United States)

^e INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; DNA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PROTEIN P53;

ARTICLE; COMPUTER PROGRAM; DATA BASE; DNA SEQUENCE; GENE MUTATION; HUMAN; INFORMATION RETRIEVAL; INFORMATION SYSTEM; INTERNET; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; TRANSGENIC ANIMAL; TUMOR SUPPRESSOR GENE;

ANIMALIA; RODENTIA;

EID: 0030860225     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/25.1.136     Document Type: Article

References (17)

1. Hollstein, M., Sidransky, D., Vogelstein, B., and Harris, C.C. (1991) p53 mutations in human cancers. Science, 253, 49-53.
2. Caron de Fromentel, C. and Soussi, T. ( 1992) TP53 tumor suppressor gene: a model for investigating human mutagenesis. Genes Chrom. Cancer, 4, 1-15.
3. Jones, I.M., Burkhart-Schultz, K., and Crippen, T.L. (1987) Cloned mouse lymphocytes permit analysis of somatic mutations that occur in vivo. Som. Cell Mol. Genet., 13, 325-333.
4. Harbach, P.R., Filipunas, A.L., Wang,Y., and Aaron, C.S. (1992) DNA sequence analysis of spontaneous and N-ethyl-N-nitrosourea-induced hprt mutations arising in vivo in cynomolgus monkey T-lymphocytes. Environ. Mol. Mutagen., 20, 96-105.
5. Albertini, R.J., O'Neill, J.P., Nicklas, J.A. Heinz, N.H., and Kelleher P.C. (1985) Alterations of the hprt gene in human in vivo-derived 6-thioguanine-resistant T lymphocytes. Nature, 316, 369-371.
6. Turner, D.R., Morley, A.A., Haliandros, M., Kutlaca, R., and Sanderson, B.J. (1985) In vivo somatic mutations in human lymphocytes frequently result from major gene alterations. Nature, 315, 343-345.
7. Provost, S.G., Kretz, PL., Hammer, R.T., Matthews, C.D., Rogers, B.J., Lundberg, K.S., Dycaico, M.J., and Short J.M. (1993) Transgenic systems for in vivo mutation analysis. Mutation Res., 288, 133-149.
8. Douglas, G.R., Jiao, J., Gingerich, J.D., Gossen, J.A. and Soper, L.M. (1995) Temporal and molecular characteristics of mutations induced by ethylnitrosourea in germ cells isolated from seminiferous tubules and in spermatozoa of lacZ transgenic mice. Proc. Nutl. Acud. Sci. USA, 92, 7486-7489.
9. Gossen, J.A., de Leeuw. W.J.F., Tan, C.H., Zwarthoff, E.G., Berends, F., Lohman, P.H.M., Knook, D.L. and Vijg, J. (1989) Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo. Proc. Nutl. Acad. Sci. USA, 86, 7971-7975.
10. Kohler, S.W., Provost, G.S., Kretz, P.L., Dycaico, MJ., Sorge, J.A. and Short, J.M. (1990) Development of a short-term, in vivo mutagenesis assay: the effects of methylation on the recovery of a lambda phagc shuttle vector from transgenic mice. Nucleic Acids Res., 18, 3007-3013.
11. Cariello, N.F., Cui, L., Beroud, C., and Soussi, T. (1994) Database and software for the analysis of mutations in the human p53 gene. Cancer Res., 54, 4454-1460.
12. Carieilo, N.F. (1994) Software for the analysis of mutations at the human hprt locus. Mutai. Res., 312, 173-185.
13. Cariello, N.F., Piegorsch, W.W., Adams, W.T., and Skopek, T.R. (1994) Computer program for the analysis of mutational spectra: application to p53 mutations. Carcinogenesis, 15, 2281-2285.
14. Cariello, N.F. Relational database model for DNA mutations and a software program for implementation of the model. Mutat. Res., in press.
15. Cariello, N.F. (1994) Database and software for the analysis of mutations at the human hprt gene. Nucleic Acids Res., 22, 3547-3548.
16. Cariello, N.F., Beroud, C., and Soussi, T. (1994) Database and software for the analysis of mutations at the human p53 gene. Nucleic Acids Res., 22, 3549-3550.
17. Cariello, N.F., Douglas, G.R. and Soussi, T. (1996) Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and the lacZ gene in transgenic rodents. Nucleic Acids Res., 24, 119-120.