SAR and pH Stability of Cyano-Substituted Epothilones

Organic Letters

Volumn 4, Issue 22, 2002, Pages 3815-3818

  Regueiro Ren, Alicia ^a   Leavitt, Kenneth ^a   Kim, Soong Hoon ^a   Höfle, Gerhard ^b   Kiffe, Michael ^b   Gougoutas, Jack Z ^a   DiMarco, John D ^a   Lee, Francis Y F ^a   Fairchild, Craig R ^a   Long, Byron H ^a   Vite, Gregory D ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EPOTHILONE DERIVATIVE; TUBULIN;

ARTICLE; CELL CULTURE; CELL DIVISION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; DRUG STABILITY; HUMAN; METABOLISM; PH; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTINEOPLASTIC AGENTS; CELL DIVISION; DRUG STABILITY; EPOTHILONES; HUMANS; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0001620405     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol026589j     Document Type: Article

References (31)

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