A unified and quantitative receptor model for the microtubule binding of paclitaxel and epothilone

Organic Letters

Volumn 1, Issue 1, 1999, Pages 43-46

  Wang, Minmin ^a   Xia, Xiaoyang ^a   Kim, Yohan ^a   Hwang, David ^a   Jansen, Johanna M ^b   Botta, Maurizio ^c   Liotta, Dennis C ^a   Snyder, James P ^a  

^a EMORY UNIVERSITY   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DRUG RECEPTOR; EPOTHILONE B; EPOTHILONE DERIVATIVE; EPOXIDE; PACLITAXEL; THIAZOLE DERIVATIVE; TUBULIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MICROTUBULE; MONTE CARLO METHOD; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; EPOTHILONES; EPOXY COMPOUNDS; MAGNETIC RESONANCE SPECTROSCOPY; MICROTUBULES; MODELS, MOLECULAR; MONTE CARLO METHOD; PACLITAXEL; PROTEIN BINDING; RECEPTORS, DRUG; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TUBULIN;

EID: 0033565018     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol990521v     Document Type: Article

References (54)

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