Antibody diversification by somatic mutation: From Burnet onwards

Immunology and Cell Biology

Volumn 86, Issue 2, 2008, Pages 124-132

  Neuberger, Michael S ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Antibody diversification; Clonal selection theory; DNA deamination; Somatic mutation

Indexed keywords

ANTIBODY; DEOXYCYTIDINE; DNA; IMMUNOGLOBULIN; POLYPEPTIDE;

ADAPTIVE IMMUNITY; AMINO ACID SEQUENCE; COMPREHENSION; DEAMINATION; GENE CONVERSION; GENE REARRANGEMENT; HUMAN; IMMUNOGLOBULIN GENE; INNATE IMMUNITY; INTROSPECTION; MOLECULAR EVOLUTION; MOLECULAR MECHANICS; NONHUMAN; REVIEW; SOMATIC MUTATION;

ANIMALS; ANTIBODIES; ANTIBODY DIVERSITY; B-LYMPHOCYTES; CYTIDINE DEAMINASE; DNA; EVOLUTION; GENE REARRANGEMENT, B-LYMPHOCYTE; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNITY; IMMUNITY, NATURAL; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN VARIABLE REGION; MODELS, IMMUNOLOGICAL; MUTATION; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 39749182247     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/sj.icb.7100160     Document Type: Review

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