An ancient evolutionary origin of the Rag1/2 gene locus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 10, 2006, Pages 3728-3733

  Fugmann, Sebastian D ^a   Messier, Cynthia ^b   Novack, Laura A ^a   Andrew Cameron, R ^c   Rast, Jonathan P ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Adaptive immune system; Evolution; Recombination activating gene

Indexed keywords

RAG1 PROTEIN; RAG2 PROTEIN;

ADAPTATION; ARTICLE; ECHINODERM; GENE; GENE CLUSTER; GENE REARRANGEMENT; GENE SEQUENCE; HORIZONTAL GENE TRANSFER; IMMUNE SYSTEM; IMMUNITY; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SPRAG1 GENE; SPRAG2 GENE; STRONGYLOCENTROTUS;

AMINO ACID SEQUENCE; ANIMALS; DNA-BINDING PROTEINS; EVOLUTION, MOLECULAR; GENE EXPRESSION; GENES, RAG-1; HOMEODOMAIN PROTEINS; LINKAGE (GENETICS); MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STRONGYLOCENTROTUS PURPURATUS;

ANIMALIA; ECHINODERMATA; GNATHOSTOMATA (VERTEBRATE); INVERTEBRATA; STRONGYLOCENTROTUS; STRONGYLOCENTROTUS PURPURATUS; VERTEBRATA;

EID: 33644856255     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0509720103     Document Type: Article

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