Discovery and development of anthrax lethal factor metalloproteinase inhibitors

Current Pharmaceutical Biotechnology

Volumn 9, Issue 1, 2008, Pages 24-33

  Turk, Benjamin E ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anthrax; Bacterial toxins; Drug discovery; Metalloenzymes; Protease inhibitors; Proteases

Indexed keywords

1,10 PHENANTHROLINE; ALPHA DEFENSIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTHRAX LETHAL FACTOR; ANTHRAX VACCINE; ANTIBIOTIC AGENT; BACTERIAL TOXIN; CATECHIN; CIPROFLOXACIN; CMT 308; DEFENSIN 1; DEFENSIN 2; DEFENSIN 3; EDETIC ACID; EPIGALLOCATECHIN GALLATE; FRAMYCETIN; GLUCOSE PENTAGALLATE; GREEN TEA EXTRACT; HYDROXAMIC ACID; ILOMASTAT; MATRIX METALLOPROTEINASE INHIBITOR; METALLOPROTEINASE; RECOMBINANT PROTECTIVE ANTIGEN 102; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTHRAX; BACILLUS ANTHRACIS; BINDING AFFINITY; BINDING SITE; CLINICAL TRIAL; COMPETITIVE INHIBITION; CRYSTAL STRUCTURE; DRUG CHOICE; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; HUMAN; MACROPHAGE; NONHUMAN; PASSIVE IMMUNIZATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW;

ANIMALS; ANTHRAX VACCINES; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; DRUG DESIGN; HUMANS; METALLOENDOPEPTIDASES; PROTEASE INHIBITORS;

ANIMALIA; BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); POSIBACTERIA;

EID: 39449131198     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920108783497604     Document Type: Review

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