-
1
-
-
0026741811
-
Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells
-
Arora, N., K. R. Klimpel, Y. Singh, and S. H. Leppla. 1992. Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells. J. Biol. Chem. 267:15542-15548.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 15542-15548
-
-
Arora, N.1
Klimpel, K.R.2
Singh, Y.3
Leppla, S.H.4
-
2
-
-
0025733702
-
Mammalian subtilisins: The long-sought dibasic processing endoproteases
-
Barr, P. J. 1991. Mammalian subtilisins: the long-sought dibasic processing endoproteases. Cell 66:1-3.
-
(1991)
Cell
, vol.66
, pp. 1-3
-
-
Barr, P.J.1
-
3
-
-
0027990837
-
The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system
-
Bosshart, H., J. Humphrey, E. Deignan, J. Davidson, J. Drazba, L. Yuan, V. Oorschot, P. J. Peters, and J. S. Bonifacino. 1994. The cytoplasmic domain mediates localization of furin to the trans-Golgi network en route to the endosomal/lysosomal system. J. Cell Biol. 126:1157-1172.
-
(1994)
J. Cell Biol.
, vol.126
, pp. 1157-1172
-
-
Bosshart, H.1
Humphrey, J.2
Deignan, E.3
Davidson, J.4
Drazba, J.5
Yuan, L.6
Oorschot, V.7
Peters, P.J.8
Bonifacino, J.S.9
-
4
-
-
0027765503
-
Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin
-
Breslin, M. B., I. Lindberg, S. Benjannet, J. P. Mathis, C. Lazure, and N. G. Seidah. 1993. Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin. J. Biol. Chem. 268:27084-27093.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 27084-27093
-
-
Breslin, M.B.1
Lindberg, I.2
Benjannet, S.3
Mathis, J.P.4
Lazure, C.5
Seidah, N.G.6
-
5
-
-
0028304478
-
Cleavage of Pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver
-
Chiron, M. F., C. M. Fryling, and D. J. FitzGerald. 1994. Cleavage of Pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver. J. Biol. Chem. 269:18167-18176.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18167-18176
-
-
Chiron, M.F.1
Fryling, C.M.2
FitzGerald, D.J.3
-
6
-
-
0027493246
-
Proprotein processing activity and cleavage site selectivity of the KEX2-like endoprotease PACE4
-
Creemers, J. W. M., P. J. G. Kormelink, A. J. M. Roebroek, K. Nakayama, and W. J. M. Vandeven. 1993. Proprotein processing activity and cleavage site selectivity of the KEX2-like endoprotease PACE4. FEBS Lett. 336:65-69.
-
(1993)
FEBS Lett.
, vol.336
, pp. 65-69
-
-
Creemers, J.W.M.1
Kormelink, P.J.G.2
Roebroek, A.J.M.3
Nakayama, K.4
Vandeven, W.J.M.5
-
7
-
-
0026353962
-
Characterization of a cellular protease that cleaves Pseudomonas exotoxin
-
Fryling, C., M. Ogata, and D. FitzGerald. 1992. Characterization of a cellular protease that cleaves Pseudomonas exotoxin. Infect. Immun. 60:497-502.
-
(1992)
Infect. Immun.
, vol.60
, pp. 497-502
-
-
Fryling, C.1
Ogata, M.2
FitzGerald, D.3
-
8
-
-
0028872463
-
Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases
-
Gordon, V. M., K. R. Klimpel, N. Arora, M. A. Henderson, and S. H. Leppla. 1995. Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases. Infect. Immun. 63:82-87.
-
(1995)
Infect. Immun.
, vol.63
, pp. 82-87
-
-
Gordon, V.M.1
Klimpel, K.R.2
Arora, N.3
Henderson, M.A.4
Leppla, S.H.5
-
9
-
-
0028089159
-
Proteolytic activation of bacterial toxins: Role of bacterial and host cell proteases
-
Gordon, V. M., and S. H. Leppla. 1994. Proteolytic activation of bacterial toxins: role of bacterial and host cell proteases. Infect. Immun. 62:333-340.
-
(1994)
Infect. Immun.
, vol.62
, pp. 333-340
-
-
Gordon, V.M.1
Leppla, S.H.2
-
10
-
-
0028091725
-
Furin activates Pseudomonas exotoxin A by specific cleavage in vivo and in vitro
-
Inocencio, N. M., J. M. Moehring, and T. J. Moehring. 1994. Furin activates Pseudomonas exotoxin A by specific cleavage in vivo and in vitro. J. Biol. Chem. 269:31831-31835.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 31831-31835
-
-
Inocencio, N.M.1
Moehring, J.M.2
Moehring, T.J.3
-
11
-
-
0026348132
-
Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15
-
Kiefer, M. C., J. E. Tucker, R. Joh, K. E. Landsberg, D. Saltman, and P. J. Barr. 1991. Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15. DNA Cell Biol. 10:757-769.
-
(1991)
DNA Cell Biol.
, vol.10
, pp. 757-769
-
-
Kiefer, M.C.1
Tucker, J.E.2
Joh, R.3
Landsberg, K.E.4
Saltman, D.5
Barr, P.J.6
-
12
-
-
1842409858
-
Cleavage of diphtheria toxin and the protective antigen of Bacillus anthracis by the eukaryotic protease furin
-
abstr. B-32, American Society for Microbiology, Washington, D.C.
-
Klimpel, K. R., S. S. Molloy, P. A. Bresnahan, G. Thomas, and S. H. Leppla. 1992. Cleavage of diphtheria toxin and the protective antigen of Bacillus anthracis by the eukaryotic protease furin, abstr. B-32, p. 31. In Abstracts of the 92nd General Meeting of the American Society for Microbiology. American Society for Microbiology, Washington, D.C.
-
(1992)
Abstracts of the 92nd General Meeting of the American Society for Microbiology
, pp. 31
-
-
Klimpel, K.R.1
Molloy, S.S.2
Bresnahan, P.A.3
Thomas, G.4
Leppla, S.H.5
-
13
-
-
0026498189
-
Anthrax toxin protective antigen is activated by a cell-surface protease with the sequence specificity and catalytic properties of furin
-
Klimpel, K. R., S. S. Molloy, G. Thomas, and S. H. Leppla. 1992. Anthrax toxin protective antigen is activated by a cell-surface protease with the sequence specificity and catalytic properties of furin. Proc. Natl. Acad. Sci. USA 89:10277-10281.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10277-10281
-
-
Klimpel, K.R.1
Molloy, S.S.2
Thomas, G.3
Leppla, S.H.4
-
14
-
-
0024214705
-
Production and purification of anthrax toxin
-
Leppla, S. H. 1988. Production and purification of anthrax toxin. Methods Enzymol. 165:103-116.
-
(1988)
Methods Enzymol.
, vol.165
, pp. 103-116
-
-
Leppla, S.H.1
-
15
-
-
0027452932
-
Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion
-
Moehring, J. M., N. M. Inocencio, B. J. Robertson, and T. J. Moehring. 1993. Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion. J. Biol. Chem. 268:2590-2594.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 2590-2594
-
-
Moehring, J.M.1
Inocencio, N.M.2
Robertson, B.J.3
Moehring, T.J.4
-
16
-
-
0028107656
-
Intracellular trafficking and activation of the furin proprotein convertase: Localization to the TGN and recycling from the cell surface
-
Molloy, S. S., L. Thomas, J. K. VanSlyke, P. E. Stenberg, and G. Thomas. 1994. Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface. EMBO J. 13:18-33.
-
(1994)
EMBO J.
, vol.13
, pp. 18-33
-
-
Molloy, S.S.1
Thomas, L.2
VanSlyke, J.K.3
Stenberg, P.E.4
Thomas, G.5
-
17
-
-
0026747170
-
Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
-
Naglich, J. G., J. E. Metherall, D. W. Russell, and L. Eidels. 1992. Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell 69:1051-1061.
-
(1992)
Cell
, vol.69
, pp. 1051-1061
-
-
Naglich, J.G.1
Metherall, J.E.2
Russell, D.W.3
Eidels, L.4
-
18
-
-
0025747514
-
Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis
-
Quinn, C. P., Y. Singh, K. R. Klimpel, and S. H. Leppla. 1991. Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis. J. Biol. Chem. 266:20124-20130.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 20124-20130
-
-
Quinn, C.P.1
Singh, Y.2
Klimpel, K.R.3
Leppla, S.H.4
-
19
-
-
1842335995
-
-
Unpublished results
-
18a.Rehemtulla, A. Unpublished results.
-
-
-
Rehemtulla, A.1
-
20
-
-
0027376534
-
PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE
-
Rehemtulla, A., P. J. Barr, C. J. Rhodes, and R. J. Kaufman. 1993. PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE. Biochemistry 32:11586-11590.
-
(1993)
Biochemistry
, vol.32
, pp. 11586-11590
-
-
Rehemtulla, A.1
Barr, P.J.2
Rhodes, C.J.3
Kaufman, R.J.4
-
21
-
-
0026720791
-
Preferred sequence requirements for cleavage of pro-von Willebrand factor by propeptide-processing enzymes
-
Rehemtulla, A., and R. J. Kaufman. 1992. Preferred sequence requirements for cleavage of pro-von Willebrand factor by propeptide-processing enzymes. Blood 79:2349-2355.
-
(1992)
Blood
, vol.79
, pp. 2349-2355
-
-
Rehemtulla, A.1
Kaufman, R.J.2
-
22
-
-
0029071584
-
Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin
-
Schafer, W., A. Stroh, S. Berghofer, J. Seiler, M. Vey, M. L. Kruse, H. F. Kern, H. D. Klerk, and W. Garten. 1995. Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin. EMBO J. 14:2424-2435.
-
(1995)
EMBO J.
, vol.14
, pp. 2424-2435
-
-
Schafer, W.1
Stroh, A.2
Berghofer, S.3
Seiler, J.4
Vey, M.5
Kruse, M.L.6
Kern, H.F.7
Klerk, H.D.8
Garten, W.9
-
23
-
-
0027193619
-
Mammalian paired basic amino acid convertases of prohormones and proproteins
-
Seidah, N. G., R. Day, M. Marcinkiewicz, and M. Chretien. 1993. Mammalian paired basic amino acid convertases of prohormones and proproteins. Ann. N. Y. Acad. Sci. 680:135-146.
-
(1993)
Ann. N. Y. Acad. Sci.
, vol.680
, pp. 135-146
-
-
Seidah, N.G.1
Day, R.2
Marcinkiewicz, M.3
Chretien, M.4
-
24
-
-
0024837128
-
A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo
-
Singh, Y., V. K. Chaudhary, and S. H. Leppla. 1989. A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo. J. Biol. Chem. 264:19103-19107.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 19103-19107
-
-
Singh, Y.1
Chaudhary, V.K.2
Leppla, S.H.3
-
25
-
-
0027968515
-
The tissue distribution of mRNAs for the PACE4 isoforms, kexin-like processing protease: PACE4C and PACE4D mRNAs are major transcripts among PACE4 isoforms
-
Tsuji, A., K. Mori, C. Hine, Y. Tamai, H. Nagamune, and Y. Matsuda. 1994. The tissue distribution of mRNAs for the PACE4 isoforms, kexin-like processing protease: PACE4C and PACE4D mRNAs are major transcripts among PACE4 isoforms. Biochem. Biophys. Res. Commun. 202:1215-1221.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.202
, pp. 1215-1221
-
-
Tsuji, A.1
Mori, K.2
Hine, C.3
Tamai, Y.4
Nagamune, H.5
Matsuda, Y.6
-
26
-
-
0027495717
-
Evidence for involvement of furin in cleavage and activation of diphtheria toxin
-
Tsuneoka, M., K. Nakayama, K. Hatsuzawa, M. Komada, N. Kitamura, and E. Mekada. 1993. Evidence for involvement of furin in cleavage and activation of diphtheria toxin. J. Biol. Chem. 268:26461-26465.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26461-26465
-
-
Tsuneoka, M.1
Nakayama, K.2
Hatsuzawa, K.3
Komada, M.4
Kitamura, N.5
Mekada, E.6
-
27
-
-
0027354037
-
Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases
-
van de Ven, W. J., A. J. Roebroek, and H. L. van Duijnhoven. 1993. Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases. Crit. Rev. Oncog. 4:115-136.
-
(1993)
Crit. Rev. Oncog.
, vol.4
, pp. 115-136
-
-
Van de Ven, W.J.1
Roebroek, A.J.2
Van Duijnhoven, H.L.3
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