메뉴 건너뛰기




Volumn 65, Issue 8, 1997, Pages 3370-3375

A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN; DIPHTHERIA TOXIN; FURIN; PROTEINASE; PSEUDOMONAS EXOTOXIN;

EID: 0030807070     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.8.3370-3375.1997     Document Type: Article
Times cited : (45)

References (27)
  • 1
    • 0026741811 scopus 로고
    • Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells
    • Arora, N., K. R. Klimpel, Y. Singh, and S. H. Leppla. 1992. Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells. J. Biol. Chem. 267:15542-15548.
    • (1992) J. Biol. Chem. , vol.267 , pp. 15542-15548
    • Arora, N.1    Klimpel, K.R.2    Singh, Y.3    Leppla, S.H.4
  • 2
    • 0025733702 scopus 로고
    • Mammalian subtilisins: The long-sought dibasic processing endoproteases
    • Barr, P. J. 1991. Mammalian subtilisins: the long-sought dibasic processing endoproteases. Cell 66:1-3.
    • (1991) Cell , vol.66 , pp. 1-3
    • Barr, P.J.1
  • 4
    • 0027765503 scopus 로고
    • Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin
    • Breslin, M. B., I. Lindberg, S. Benjannet, J. P. Mathis, C. Lazure, and N. G. Seidah. 1993. Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin. J. Biol. Chem. 268:27084-27093.
    • (1993) J. Biol. Chem. , vol.268 , pp. 27084-27093
    • Breslin, M.B.1    Lindberg, I.2    Benjannet, S.3    Mathis, J.P.4    Lazure, C.5    Seidah, N.G.6
  • 5
    • 0028304478 scopus 로고
    • Cleavage of Pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver
    • Chiron, M. F., C. M. Fryling, and D. J. FitzGerald. 1994. Cleavage of Pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver. J. Biol. Chem. 269:18167-18176.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18167-18176
    • Chiron, M.F.1    Fryling, C.M.2    FitzGerald, D.J.3
  • 6
    • 0027493246 scopus 로고
    • Proprotein processing activity and cleavage site selectivity of the KEX2-like endoprotease PACE4
    • Creemers, J. W. M., P. J. G. Kormelink, A. J. M. Roebroek, K. Nakayama, and W. J. M. Vandeven. 1993. Proprotein processing activity and cleavage site selectivity of the KEX2-like endoprotease PACE4. FEBS Lett. 336:65-69.
    • (1993) FEBS Lett. , vol.336 , pp. 65-69
    • Creemers, J.W.M.1    Kormelink, P.J.G.2    Roebroek, A.J.M.3    Nakayama, K.4    Vandeven, W.J.M.5
  • 7
    • 0026353962 scopus 로고
    • Characterization of a cellular protease that cleaves Pseudomonas exotoxin
    • Fryling, C., M. Ogata, and D. FitzGerald. 1992. Characterization of a cellular protease that cleaves Pseudomonas exotoxin. Infect. Immun. 60:497-502.
    • (1992) Infect. Immun. , vol.60 , pp. 497-502
    • Fryling, C.1    Ogata, M.2    FitzGerald, D.3
  • 8
    • 0028872463 scopus 로고
    • Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases
    • Gordon, V. M., K. R. Klimpel, N. Arora, M. A. Henderson, and S. H. Leppla. 1995. Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases. Infect. Immun. 63:82-87.
    • (1995) Infect. Immun. , vol.63 , pp. 82-87
    • Gordon, V.M.1    Klimpel, K.R.2    Arora, N.3    Henderson, M.A.4    Leppla, S.H.5
  • 9
    • 0028089159 scopus 로고
    • Proteolytic activation of bacterial toxins: Role of bacterial and host cell proteases
    • Gordon, V. M., and S. H. Leppla. 1994. Proteolytic activation of bacterial toxins: role of bacterial and host cell proteases. Infect. Immun. 62:333-340.
    • (1994) Infect. Immun. , vol.62 , pp. 333-340
    • Gordon, V.M.1    Leppla, S.H.2
  • 10
    • 0028091725 scopus 로고
    • Furin activates Pseudomonas exotoxin A by specific cleavage in vivo and in vitro
    • Inocencio, N. M., J. M. Moehring, and T. J. Moehring. 1994. Furin activates Pseudomonas exotoxin A by specific cleavage in vivo and in vitro. J. Biol. Chem. 269:31831-31835.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31831-31835
    • Inocencio, N.M.1    Moehring, J.M.2    Moehring, T.J.3
  • 11
    • 0026348132 scopus 로고
    • Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15
    • Kiefer, M. C., J. E. Tucker, R. Joh, K. E. Landsberg, D. Saltman, and P. J. Barr. 1991. Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15. DNA Cell Biol. 10:757-769.
    • (1991) DNA Cell Biol. , vol.10 , pp. 757-769
    • Kiefer, M.C.1    Tucker, J.E.2    Joh, R.3    Landsberg, K.E.4    Saltman, D.5    Barr, P.J.6
  • 13
    • 0026498189 scopus 로고
    • Anthrax toxin protective antigen is activated by a cell-surface protease with the sequence specificity and catalytic properties of furin
    • Klimpel, K. R., S. S. Molloy, G. Thomas, and S. H. Leppla. 1992. Anthrax toxin protective antigen is activated by a cell-surface protease with the sequence specificity and catalytic properties of furin. Proc. Natl. Acad. Sci. USA 89:10277-10281.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10277-10281
    • Klimpel, K.R.1    Molloy, S.S.2    Thomas, G.3    Leppla, S.H.4
  • 14
    • 0024214705 scopus 로고
    • Production and purification of anthrax toxin
    • Leppla, S. H. 1988. Production and purification of anthrax toxin. Methods Enzymol. 165:103-116.
    • (1988) Methods Enzymol. , vol.165 , pp. 103-116
    • Leppla, S.H.1
  • 15
    • 0027452932 scopus 로고
    • Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion
    • Moehring, J. M., N. M. Inocencio, B. J. Robertson, and T. J. Moehring. 1993. Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion. J. Biol. Chem. 268:2590-2594.
    • (1993) J. Biol. Chem. , vol.268 , pp. 2590-2594
    • Moehring, J.M.1    Inocencio, N.M.2    Robertson, B.J.3    Moehring, T.J.4
  • 16
    • 0028107656 scopus 로고
    • Intracellular trafficking and activation of the furin proprotein convertase: Localization to the TGN and recycling from the cell surface
    • Molloy, S. S., L. Thomas, J. K. VanSlyke, P. E. Stenberg, and G. Thomas. 1994. Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface. EMBO J. 13:18-33.
    • (1994) EMBO J. , vol.13 , pp. 18-33
    • Molloy, S.S.1    Thomas, L.2    VanSlyke, J.K.3    Stenberg, P.E.4    Thomas, G.5
  • 17
    • 0026747170 scopus 로고
    • Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
    • Naglich, J. G., J. E. Metherall, D. W. Russell, and L. Eidels. 1992. Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell 69:1051-1061.
    • (1992) Cell , vol.69 , pp. 1051-1061
    • Naglich, J.G.1    Metherall, J.E.2    Russell, D.W.3    Eidels, L.4
  • 18
    • 0025747514 scopus 로고
    • Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis
    • Quinn, C. P., Y. Singh, K. R. Klimpel, and S. H. Leppla. 1991. Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis. J. Biol. Chem. 266:20124-20130.
    • (1991) J. Biol. Chem. , vol.266 , pp. 20124-20130
    • Quinn, C.P.1    Singh, Y.2    Klimpel, K.R.3    Leppla, S.H.4
  • 19
    • 1842335995 scopus 로고    scopus 로고
    • Unpublished results
    • 18a.Rehemtulla, A. Unpublished results.
    • Rehemtulla, A.1
  • 20
    • 0027376534 scopus 로고
    • PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE
    • Rehemtulla, A., P. J. Barr, C. J. Rhodes, and R. J. Kaufman. 1993. PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE. Biochemistry 32:11586-11590.
    • (1993) Biochemistry , vol.32 , pp. 11586-11590
    • Rehemtulla, A.1    Barr, P.J.2    Rhodes, C.J.3    Kaufman, R.J.4
  • 21
    • 0026720791 scopus 로고
    • Preferred sequence requirements for cleavage of pro-von Willebrand factor by propeptide-processing enzymes
    • Rehemtulla, A., and R. J. Kaufman. 1992. Preferred sequence requirements for cleavage of pro-von Willebrand factor by propeptide-processing enzymes. Blood 79:2349-2355.
    • (1992) Blood , vol.79 , pp. 2349-2355
    • Rehemtulla, A.1    Kaufman, R.J.2
  • 22
    • 0029071584 scopus 로고
    • Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin
    • Schafer, W., A. Stroh, S. Berghofer, J. Seiler, M. Vey, M. L. Kruse, H. F. Kern, H. D. Klerk, and W. Garten. 1995. Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin. EMBO J. 14:2424-2435.
    • (1995) EMBO J. , vol.14 , pp. 2424-2435
    • Schafer, W.1    Stroh, A.2    Berghofer, S.3    Seiler, J.4    Vey, M.5    Kruse, M.L.6    Kern, H.F.7    Klerk, H.D.8    Garten, W.9
  • 23
    • 0027193619 scopus 로고
    • Mammalian paired basic amino acid convertases of prohormones and proproteins
    • Seidah, N. G., R. Day, M. Marcinkiewicz, and M. Chretien. 1993. Mammalian paired basic amino acid convertases of prohormones and proproteins. Ann. N. Y. Acad. Sci. 680:135-146.
    • (1993) Ann. N. Y. Acad. Sci. , vol.680 , pp. 135-146
    • Seidah, N.G.1    Day, R.2    Marcinkiewicz, M.3    Chretien, M.4
  • 24
    • 0024837128 scopus 로고
    • A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo
    • Singh, Y., V. K. Chaudhary, and S. H. Leppla. 1989. A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo. J. Biol. Chem. 264:19103-19107.
    • (1989) J. Biol. Chem. , vol.264 , pp. 19103-19107
    • Singh, Y.1    Chaudhary, V.K.2    Leppla, S.H.3
  • 25
    • 0027968515 scopus 로고
    • The tissue distribution of mRNAs for the PACE4 isoforms, kexin-like processing protease: PACE4C and PACE4D mRNAs are major transcripts among PACE4 isoforms
    • Tsuji, A., K. Mori, C. Hine, Y. Tamai, H. Nagamune, and Y. Matsuda. 1994. The tissue distribution of mRNAs for the PACE4 isoforms, kexin-like processing protease: PACE4C and PACE4D mRNAs are major transcripts among PACE4 isoforms. Biochem. Biophys. Res. Commun. 202:1215-1221.
    • (1994) Biochem. Biophys. Res. Commun. , vol.202 , pp. 1215-1221
    • Tsuji, A.1    Mori, K.2    Hine, C.3    Tamai, Y.4    Nagamune, H.5    Matsuda, Y.6
  • 26
  • 27
    • 0027354037 scopus 로고
    • Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases
    • van de Ven, W. J., A. J. Roebroek, and H. L. van Duijnhoven. 1993. Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases. Crit. Rev. Oncog. 4:115-136.
    • (1993) Crit. Rev. Oncog. , vol.4 , pp. 115-136
    • Van de Ven, W.J.1    Roebroek, A.J.2    Van Duijnhoven, H.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.