Chemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor

Nature Biotechnology

Volumn 22, Issue 6, 2004, Pages 717-723

  Min, Dal Hee ^a   Tang, Wei Jen ^b   Mrksich, Milan ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; DESORPTION; ENZYME INHIBITION; IONIZATION; LASERS; MASS SPECTROMETRY;

BIOLOGICAL ANALYTES; CHEMICAL SCREENING; LIGANDS;

SCREENING;

ANTHRAX TOXIN; ANTITOXIN; DS 998; MITOGEN ACTIVATED PROTEIN KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS ANTHRACIS; CONCENTRATION RESPONSE; DRUG SCREENING; ENZYME INHIBITOR INTERACTION; HUMAN; HUMAN CELL; LIGAND BINDING; MACROPHAGE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL;

ANTIGENS, BACTERIAL; APOPTOSIS; BACTERIAL TOXINS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HEMAGGLUTININS; HUMANS; KINETICS; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE KINASE 1; PEPTIDES; RECOMBINANT FUSION PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSFECTION;

ANTHRAX; BACILLUS ANTHRACIS;

EID: 2542627454     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt973     Document Type: Article

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