Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNγ-induced release of NO and TNFα

FEBS Letters

Volumn 462, Issue 1-2, 1999, Pages 199-204

  Pellizzari, Rossella ^a   Guidi Rontani, Chantal ^b   Vitale, Gaetano ^a   Mock, Michèle ^b   Montecucco, Cesare ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b INSTITUT PASTEUR   (France)

Author keywords

Anthrax; Cytokine; Inflammation; Lethal factor; Metalloprotease; Mitogen activated protein kinase kinase

Indexed keywords

ANTHRAX TOXIN; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; ZINC;

ANIMAL CELL; ARTICLE; BACILLUS ANTHRACIS; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; CYTOSOL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; LETHALITY; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM CELL; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; CELLS, CULTURED; DRUG INTERACTIONS; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MACROPHAGES, PERITONEAL; MAP KINASE KINASE 2; MAP KINASE KINASE 3; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NITRIC OXIDE; PROTEIN-TYROSINE KINASES; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; ANTHRAX; BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS);

EID: 0032755353     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01502-1     Document Type: Article

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