The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor

Nature Structural and Molecular Biology

Volumn 11, Issue 1, 2004, Pages 60-66

  Turk, Benjamin E ^a,b   Wong, Thiang Yian ^c   Schwarzenbacher, Robert ^c   Jarrell, Emily T ^a,b   Leppla, Stephen H ^d   Collier, R John ^b   Liddington, Robert C ^c   Cantley, Lewis C ^a,b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BURNHAM INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX LETHAL FACTOR; METALLOPROTEINASE; PEPTIDE DERIVATIVE; PEPTIDE LIBRARY; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTHRAX; ARTICLE; CELL CULTURE; CELL PROTECTION; COMPETITIVE INHIBITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOLYSIS; DRUG DESIGN; ENZYME INHIBITION; ENZYME SUBSTRATE; IN VITRO STUDY; LETHAL GENE; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANTHRAX; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; HUMANS; KINETICS; MACROMOLECULAR SUBSTANCES; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PEPTIDE LIBRARY; SUBSTRATE SPECIFICITY;

ANIMALIA; ANTHRAX; POSIBACTERIA;

EID: 0347192782     PISSN: 15459993     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsmb708     Document Type: Article

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