-
1
-
-
0347505003
-
CD28-mediated co-stimulation: A quantitative support for TCR signalling
-
Acuto, O., and Michel, F. 2003. CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat. Rev. Immunol. 3, 939-951.
-
(2003)
Nat. Rev. Immunol
, vol.3
, pp. 939-951
-
-
Acuto, O.1
Michel, F.2
-
2
-
-
0033082989
-
Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands
-
Alam, S.M., Davies, G.M., et al. 1999. Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. Immunity 10, 227-237.
-
(1999)
Immunity
, vol.10
, pp. 227-237
-
-
Alam, S.M.1
Davies, G.M.2
-
3
-
-
17144383216
-
Cooperativity during the formation of peptide/MHC class II complexes
-
Anderson, M.W., and Gorski, J. 2005. Cooperativity during the formation of peptide/MHC class II complexes. Biochemistry 44, 5617-5624.
-
(2005)
Biochemistry
, vol.44
, pp. 5617-5624
-
-
Anderson, M.W.1
Gorski, J.2
-
4
-
-
0035914485
-
beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes
-
beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes. J. Exp. Med. 194, 1485-1495.
-
(2001)
J. Exp. Med
, vol.194
, pp. 1485-1495
-
-
Arcaro, A.1
Gregoire, C.2
-
5
-
-
0027252136
-
- T lymphocytes. Antigenic and functional properties
-
- T lymphocytes. Antigenic and functional properties. J. Immunol. 150, 1147-1159.
-
(1993)
J. Immunol
, vol.150
, pp. 1147-1159
-
-
Azuma, M.1
Phillips, J.H.2
-
6
-
-
0029845747
-
T cell responses are governed by avidity and co-stimulatory thresholds
-
Bachmann, M.F., Sebzda, E., et al. 1996. T cell responses are governed by avidity and co-stimulatory thresholds. Eur. J. Immunol. 26, 2017-2022.
-
(1996)
Eur. J. Immunol
, vol.26
, pp. 2017-2022
-
-
Bachmann, M.F.1
Sebzda, E.2
-
7
-
-
0021266843
-
Lymphokine regulation of human lymphocyte proliferation: Formation of resting G0 cells by removal of interleukin 2 in cultures of proliferating T lymphocytes
-
Bettens, F., Kristensen, F., et al. 1984. Lymphokine regulation of human lymphocyte proliferation: formation of resting G0 cells by removal of interleukin 2 in cultures of proliferating T lymphocytes. Cell Immunol. 86, 337-346.
-
(1984)
Cell Immunol
, vol.86
, pp. 337-346
-
-
Bettens, F.1
Kristensen, F.2
-
8
-
-
0028907064
-
CD69 antigen of human lymphocytes is a calcium-dependent carbohydrate-binding protein
-
Bezouska, K., Nepovim, A., et al. 1995. CD69 antigen of human lymphocytes is a calcium-dependent carbohydrate-binding protein. Biochem. Biophys. Res. Commun. 208, 68-74.
-
(1995)
Biochem. Biophys. Res. Commun
, vol.208
, pp. 68-74
-
-
Bezouska, K.1
Nepovim, A.2
-
9
-
-
0036681970
-
(+) memory T cell activation requirements at the single clonotype level
-
(+) memory T cell activation requirements at the single clonotype level. J. Immunol. 169, 1207-1218.
-
(2002)
J. Immunol
, vol.169
, pp. 1207-1218
-
-
Bitmansour, A.D.1
Douek, D.C.2
-
10
-
-
0031795316
-
Kinetics of T cell proliferation: A mathematical model and data analysis
-
Borisova, L.R., Andreev, S.G., et al. 1998. Kinetics of T cell proliferation: a mathematical model and data analysis. Membr. Cell Biol. 12, 111-119.
-
(1998)
Membr. Cell Biol
, vol.12
, pp. 111-119
-
-
Borisova, L.R.1
Andreev, S.G.2
-
11
-
-
0030611755
-
A mathematical model of T lymphocyte proliferation controlled by interleukin-2 internalization
-
Borisova, L.R., Kuznetsov, V.A. 1997. A mathematical model of T lymphocyte proliferation controlled by interleukin-2 internalization. Membr. Cell Biol. 11, 259-267.
-
(1997)
Membr. Cell Biol
, vol.11
, pp. 259-267
-
-
Borisova, L.R.1
Kuznetsov, V.A.2
-
12
-
-
0033566825
-
IL-2-independent activation and proliferation in human T cells induced by CD28
-
Boulougouris, G., McLeod, J.D., et al. 1999. IL-2-independent activation and proliferation in human T cells induced by CD28. J. Immunol. 163, 1809-1816.
-
(1999)
J. Immunol
, vol.163
, pp. 1809-1816
-
-
Boulougouris, G.1
McLeod, J.D.2
-
13
-
-
0035202768
-
The immunological synapse and CD28-CD80 interactions
-
Bromley, S.K., Iaboni, A., et al. 2001. The immunological synapse and CD28-CD80 interactions. Nat. Immunol. 2, 1159-1166.
-
(2001)
Nat. Immunol
, vol.2
, pp. 1159-1166
-
-
Bromley, S.K.1
Iaboni, A.2
-
14
-
-
0032080641
-
MHC class I/peptide stability: Implications for immunodominance, in vitro proliferation, and diversity of responding CTL
-
Busch, D.H., and Pamer, E.G. 1998. MHC class I/peptide stability: implications for immunodominance, in vitro proliferation, and diversity of responding CTL. J. Immunol. 160, 4441-4448.
-
(1998)
J. Immunol
, vol.160
, pp. 4441-4448
-
-
Busch, D.H.1
Pamer, E.G.2
-
15
-
-
0032197528
-
Signalling through the TCR
-
Cantrell, D., Bluestone, J., et al. 1998. Signalling through the TCR. Res. Immunol. 149, 866-867.
-
(1998)
Res. Immunol
, vol.149
, pp. 866-867
-
-
Cantrell, D.1
Bluestone, J.2
-
16
-
-
0030597113
-
A model of the immune network with B-T cell co-operation. I - Prototypical structures and dynamics
-
Carneiro, J., Coutinho, A., et al. 1996. A model of the immune network with B-T cell co-operation. I - Prototypical structures and dynamics. J. Theor. Biol. 182, 513-529.
-
(1996)
J. Theor. Biol
, vol.182
, pp. 513-529
-
-
Carneiro, J.1
Coutinho, A.2
-
17
-
-
0036214017
-
The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
-
Carreno, B.M., and Collins, M. 2002. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu. Rev. Immunol. 20, 29-53.
-
(2002)
Annu. Rev. Immunol
, vol.20
, pp. 29-53
-
-
Carreno, B.M.1
Collins, M.2
-
18
-
-
31444432986
-
Modulation of T cell function by TCR/pMHC binding kinetics
-
Carreno, L.J., Gonzalez, P.A., et al. 2006. Modulation of T cell function by TCR/pMHC binding kinetics. Immunobiology 211, 47-64.
-
(2006)
Immunobiology
, vol.211
, pp. 47-64
-
-
Carreno, L.J.1
Gonzalez, P.A.2
-
19
-
-
33646150237
-
Immune synapses in T-cell activation
-
Cemerski, S., and Shaw, A. 2006. Immune synapses in T-cell activation. Curr. Opin. Immunol. 18, 298-304.
-
(2006)
Curr. Opin. Immunol
, vol.18
, pp. 298-304
-
-
Cemerski, S.1
Shaw, A.2
-
20
-
-
0142092630
-
In silico models for cellular and molecular immunology: Successes, promises and challenges
-
Chakraborty, A.K., Dustin, M.L., et al. 2003. In silico models for cellular and molecular immunology: successes, promises and challenges. Nat. Immunol. 4, 933-936.
-
(2003)
Nat. Immunol
, vol.4
, pp. 933-936
-
-
Chakraborty, A.K.1
Dustin, M.L.2
-
21
-
-
0036795530
-
Activated TCRs remain marked for internalization after dissociation from pMHC
-
Coombs, D., Kalergis, A.M., et al. 2002. Activated TCRs remain marked for internalization after dissociation from pMHC. Nat. Immunol. 3, 926-931.
-
(2002)
Nat. Immunol
, vol.3
, pp. 926-931
-
-
Coombs, D.1
Kalergis, A.M.2
-
22
-
-
0028120414
-
T cell receptor-MHC class I peptide interactions: Affinity, kinetics, and specificity
-
Corr, M., Slanetz, A.E., et al. 1994. T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity. Science 265, 946-949.
-
(1994)
Science
, vol.265
, pp. 946-949
-
-
Corr, M.1
Slanetz, A.E.2
-
23
-
-
0027448577
-
Transcriptional regulation of interleukin-2 gene expression by CD69-generated signals
-
D'Ambrosio, D., Trotta, R., et al. 1993. Transcriptional regulation of interleukin-2 gene expression by CD69-generated signals. Eur. J. Immunol. 23, 2993-2997.
-
(1993)
Eur. J. Immunol
, vol.23
, pp. 2993-2997
-
-
D'Ambrosio, D.1
Trotta, R.2
-
24
-
-
0033558102
-
Cutting edge: The CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes
-
D'Oro, U., and Ashwell, J.D. 1999. Cutting edge: the CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes. J. Immunol. 162, 1879-1883.
-
(1999)
J. Immunol
, vol.162
, pp. 1879-1883
-
-
D'Oro, U.1
Ashwell, J.D.2
-
25
-
-
0037340388
-
The nature of molecular recognition by T cells
-
Davis, S.J., Ikemizu, S., et al. 2003. The nature of molecular recognition by T cells. Nat. Immunol. 4, 217-224.
-
(2003)
Nat. Immunol
, vol.4
, pp. 217-224
-
-
Davis, S.J.1
Ikemizu, S.2
-
26
-
-
33746114879
-
The kinetic-segregation model: TCR triggering and beyond
-
Davis, S.J., and van der Merwe, P.A. 2006. The kinetic-segregation model: TCR triggering and beyond. Nat. Immunol. 7, 803-809.
-
(2006)
Nat. Immunol
, vol.7
, pp. 803-809
-
-
Davis, S.J.1
van der Merwe, P.A.2
-
27
-
-
0025182003
-
The minimal number of class II MHC-antigen complexes needed for T cell activation
-
Demotz, S., Grey, H.M., et al. 1990. The minimal number of class II MHC-antigen complexes needed for T cell activation. Science 249, 1028-1030.
-
(1990)
Science
, vol.249
, pp. 1028-1030
-
-
Demotz, S.1
Grey, H.M.2
-
28
-
-
0035399799
-
Critical role for CD8 in binding of MHC tetramers to TCR: CD8 antibodies block specific binding of human tumor-specific MHC-peptide tetramers to TCR
-
Denkberg, G., Cohen, C.J., et al. 2001. Critical role for CD8 in binding of MHC tetramers to TCR: CD8 antibodies block specific binding of human tumor-specific MHC-peptide tetramers to TCR. J. Immunol. 167, 270-276.
-
(2001)
J. Immunol
, vol.167
, pp. 270-276
-
-
Denkberg, G.1
Cohen, C.J.2
-
29
-
-
0036604251
-
Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling
-
Dietrich, J., Menne, C., et al. 2002. Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling. J. Immunol. 168, 5434-5440.
-
(2002)
J. Immunol
, vol.168
, pp. 5434-5440
-
-
Dietrich, J.1
Menne, C.2
-
30
-
-
0030727118
-
The T cell surface protein, CD28
-
Edmead, C.E., Lamb, J.R., et al. 1997. The T cell surface protein, CD28. Int. J. Biochem. Cell. Biol. 29, 1053-1057.
-
(1997)
Int. J. Biochem. Cell. Biol
, vol.29
, pp. 1053-1057
-
-
Edmead, C.E.1
Lamb, J.R.2
-
31
-
-
0034281442
-
Computational model for effects of ligand/receptor binding properties on interleukin-2 trafficking dynamics and T cell proliferation response
-
Fallon, E.M., and Lauffenburger, D.A. 2000. Computational model for effects of ligand/receptor binding properties on interleukin-2 trafficking dynamics and T cell proliferation response. Biotechnol. Prog. 16, 905-916.
-
(2000)
Biotechnol. Prog
, vol.16
, pp. 905-916
-
-
Fallon, E.M.1
Lauffenburger, D.A.2
-
32
-
-
0042847271
-
Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling
-
Faroudi, M., Zaru, R., et al. 2003. Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling. J. Immunol. 171, 1128-1132.
-
(2003)
J. Immunol
, vol.171
, pp. 1128-1132
-
-
Faroudi, M.1
Zaru, R.2
-
33
-
-
0035211030
-
TCR dynamics on the surface of living T cells
-
Favier, B., Burroughs, N.J., et al. 2001. TCR dynamics on the surface of living T cells. Int. Immunol. 13, 1525-1532.
-
(2001)
Int. Immunol
, vol.13
, pp. 1525-1532
-
-
Favier, B.1
Burroughs, N.J.2
-
34
-
-
0031025696
-
CD4 dependence of activation threshold and TCR signalling in mouse T lymphocytes
-
Feito, M.J., Ballester, S., et al. 1997. CD4 dependence of activation threshold and TCR signalling in mouse T lymphocytes. Scand. J. Immunol. 45, 166-174.
-
(1997)
Scand. J. Immunol
, vol.45
, pp. 166-174
-
-
Feito, M.J.1
Ballester, S.2
-
35
-
-
33744909839
-
TCR-dependent cell response is modulated by the timing of CD43 engagement
-
Fierro, N.A., Pedraza-Alva, G., et al. 2006. TCR-dependent cell response is modulated by the timing of CD43 engagement. J. Immunol. 176, 7346-7353.
-
(2006)
J. Immunol
, vol.176
, pp. 7346-7353
-
-
Fierro, N.A.1
Pedraza-Alva, G.2
-
36
-
-
33751403091
-
Geometrically repatterned immunological synapses uncover formation mechanisms
-
Figge, M.T., and Meyer-Hermann, M. 2006. Geometrically repatterned immunological synapses uncover formation mechanisms. PLoS Comput. Biol. 2, e171.
-
(2006)
PLoS Comput. Biol
, vol.2
-
-
Figge, M.T.1
Meyer-Hermann, M.2
-
37
-
-
0031283279
-
Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: Affinity measurements and crystallization
-
Garcia, K.C., Tallquist, M.D., et al. 1997. Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization. Proc. Natl. Acad. Sci. USA 94, 13838-13843.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13838-13843
-
-
Garcia, K.C.1
Tallquist, M.D.2
-
38
-
-
0033748427
-
(+) T cells without an organized immunological synapse
-
(+) T cells without an organized immunological synapse. Eur. J. Immunol. 30, 3266-3270.
-
(2000)
Eur. J. Immunol
, vol.30
, pp. 3266-3270
-
-
Goldstein, J.S.1
Chen, T.2
-
39
-
-
16344370564
-
T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell
-
Gonzalez, P.A., Carreno, L.J., et al. 2005. T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell. Proc. Natl. Acad. Sci. USA 102, 4824-4829.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4824-4829
-
-
Gonzalez, P.A.1
Carreno, L.J.2
-
40
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
Grakoui, A., Bromley, S.K., et al. 1999. The immunological synapse: a molecular machine controlling T cell activation. Science 285, 221-227.
-
(1999)
Science
, vol.285
, pp. 221-227
-
-
Grakoui, A.1
Bromley, S.K.2
-
41
-
-
9144226256
-
TCR affinity and negative regulation limit autoimmunity
-
Gronski, M.A., Boulter, J.M., et al. 2004. TCR affinity and negative regulation limit autoimmunity. Nat. Med. 10, 1234-1239.
-
(2004)
Nat. Med
, vol.10
, pp. 1234-1239
-
-
Gronski, M.A.1
Boulter, J.M.2
-
42
-
-
0030007165
-
Class I MHC presentation of exogenous antigens
-
Harding, C.V. 1996. Class I MHC presentation of exogenous antigens. J. Clin. Immunol. 16, 90-96.
-
(1996)
J. Clin. Immunol
, vol.16
, pp. 90-96
-
-
Harding, C.V.1
-
43
-
-
0036739732
-
Kinetic proofreading in receptor-mediated transduction of cellular signals: Receptor aggregation, partially activated receptors, and cytosolic messengers
-
Hlavacek, W.S., Redondo, A., et al. 2002. Kinetic proofreading in receptor-mediated transduction of cellular signals: receptor aggregation, partially activated receptors, and cytosolic messengers. Bull. Math. Biol. 64, 887-911.
-
(2002)
Bull. Math. Biol
, vol.64
, pp. 887-911
-
-
Hlavacek, W.S.1
Redondo, A.2
-
44
-
-
0032528403
-
+ CTL clones is determined by the frequency of serial TCR engagement
-
+ CTL clones is determined by the frequency of serial TCR engagement. J. Immunol. 161, 553-562.
-
(1998)
J. Immunol
, vol.161
, pp. 553-562
-
-
Hudrisier, D.1
Kessler, B.2
-
45
-
-
0034599597
-
T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells
-
Hwang, I., Huang, J.F., et al. 2000. T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells. J. Exp. Med. 191, 1137-1148.
-
(2000)
J. Exp. Med
, vol.191
, pp. 1137-1148
-
-
Hwang, I.1
Huang, J.F.2
-
46
-
-
0037167816
-
Direct observation of ligand recognition by T cells
-
Irvine, D.J., Purbhoo, M.A., et al. 2002. Direct observation of ligand recognition by T cells. Nature 419, 845-849.
-
(2002)
Nature
, vol.419
, pp. 845-849
-
-
Irvine, D.J.1
Purbhoo, M.A.2
-
47
-
-
0033558278
-
Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: Relationship to the quality of individual TCR signaling events
-
Itoh, Y., Hemmer, B., et al. 1999. Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: relationship to the quality of individual TCR signaling events. J. Immunol. 162, 2073-2080.
-
(1999)
J. Immunol
, vol.162
, pp. 2073-2080
-
-
Itoh, Y.1
Hemmer, B.2
-
48
-
-
0035286588
-
Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex
-
Kalergis, A.M., Boucheron, N., et al. 2001. Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex. Nat. Immunol. 2, 229-234.
-
(2001)
Nat. Immunol
, vol.2
, pp. 229-234
-
-
Kalergis, A.M.1
Boucheron, N.2
-
49
-
-
10744227843
-
Interplay between TCR affinity and necessity of coreceptor ligation: High-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement
-
Kerry, S.E., Buslepp, J., et al. 2003. Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement. J. Immunol. 171, 4493-4503.
-
(2003)
J. Immunol
, vol.171
, pp. 4493-4503
-
-
Kerry, S.E.1
Buslepp, J.2
-
50
-
-
0035284831
-
Structural and functional consequences of altering a peptide MHC anchor residue
-
Kersh, G.J., Miley, M.J., et al. 2001. Structural and functional consequences of altering a peptide MHC anchor residue. J. Immunol. 166, 3345-3354.
-
(2001)
J. Immunol
, vol.166
, pp. 3345-3354
-
-
Kersh, G.J.1
Miley, M.J.2
-
51
-
-
18844365885
-
Coevolution of TCR-MHC interactions: Conserved MHC tertiary structure is not sufficient for interactions with the TCR
-
Kim, H.J., Guo, D., et al. 2005. Coevolution of TCR-MHC interactions: conserved MHC tertiary structure is not sufficient for interactions with the TCR. Proc. Natl. Acad. Sci. USA 102, 7263-7267.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 7263-7267
-
-
Kim, H.J.1
Guo, D.2
-
52
-
-
0033152578
-
Induction of T cell anergy by low numbers of agonist ligands
-
Korb, L.C., Mirshahidi, S., et al. 1999. Induction of T cell anergy by low numbers of agonist ligands. J. Immunol. 162, 6401-6409.
-
(1999)
J. Immunol
, vol.162
, pp. 6401-6409
-
-
Korb, L.C.1
Mirshahidi, S.2
-
54
-
-
0028129259
-
Influence of CD28 co-stimulation on cytokine production is mainly regulated via interleukin-2
-
Kuiper, H.M., de Jong, R., et al. 1994. Influence of CD28 co-stimulation on cytokine production is mainly regulated via interleukin-2. Immunology 83, 38-44.
-
(1994)
Immunology
, vol.83
, pp. 38-44
-
-
Kuiper, H.M.1
de Jong, R.2
-
55
-
-
0035191130
-
An integrative model of regulation centered on recognition of TCR peptide/MHC complexes
-
Kumar, V., and Sercarz, E. 2001. An integrative model of regulation centered on recognition of TCR peptide/MHC complexes. Immunol. Rev. 182, 113-121.
-
(2001)
Immunol. Rev
, vol.182
, pp. 113-121
-
-
Kumar, V.1
Sercarz, E.2
-
56
-
-
0034907484
-
How much TCR does a T cell need?
-
Labrecque, N., Whitfield, L.S., et al. 2001. How much TCR does a T cell need? Immunity 15, 71-82.
-
(2001)
Immunity
, vol.15
, pp. 71-82
-
-
Labrecque, N.1
Whitfield, L.S.2
-
57
-
-
0034305809
-
Kinetics of dendritic cell activation: Impact on priming of TH1, TH2 and nonpolarized T cells
-
Langenkamp, A., Messi, M., et al. 2000. Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells. Nat. Immunol. 1, 311-316.
-
(2000)
Nat. Immunol
, vol.1
, pp. 311-316
-
-
Langenkamp, A.1
Messi, M.2
-
58
-
-
0033534678
-
From TCR engagement to T cell activation: A kinetic view of T cell behavior
-
Lanzavecchia, A., Lezzi, G., et al. 1999. From TCR engagement to T cell activation: a kinetic view of T cell behavior. Cell 96, 1-4.
-
(1999)
Cell
, vol.96
, pp. 1-4
-
-
Lanzavecchia, A.1
Lezzi, G.2
-
59
-
-
0025234426
-
CD28 ligation in T-cell activation: Evidence for two signal transduction pathways
-
Ledbetter, J.A., Imboden, J.B., et al. 1990. CD28 ligation in T-cell activation: evidence for two signal transduction pathways. Blood 75, 1531-1539.
-
(1990)
Blood
, vol.75
, pp. 1531-1539
-
-
Ledbetter, J.A.1
Imboden, J.B.2
-
60
-
-
0037154747
-
T cell receptor signaling precedes immunological synapse formation
-
Lee, K.H., Holdorf, A.D., et al. 2002a. T cell receptor signaling precedes immunological synapse formation. Science 295, 1539-1542.
-
(2002)
Science
, vol.295
, pp. 1539-1542
-
-
Lee, K.H.1
Holdorf, A.D.2
-
61
-
-
0344490337
-
Low T cell receptor expression and thermal fluctuations contribute to formation of dynamic multifocal synapses in thymocytes
-
Lee, S.J., Hori, Y., et al. 2003. Low T cell receptor expression and thermal fluctuations contribute to formation of dynamic multifocal synapses in thymocytes. Proc. Natl. Acad. Sci. USA 100, 4383-4388.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4383-4388
-
-
Lee, S.J.1
Hori, Y.2
-
62
-
-
0036776238
-
Correlation of a dynamic model for immunological synapse formation with effector functions: Two pathways to synapse formation
-
Lee, S.J., Hori, Y., et al. 2002b. Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation. Trends Immunol. 23, 492-499.
-
(2002)
Trends Immunol
, vol.23
, pp. 492-499
-
-
Lee, S.J.1
Hori, Y.2
-
63
-
-
0035340973
-
Three-cell interactions in T cell-mediated suppression? A mathematical analysis of its quantitative implications
-
Leon, K., Perez, R., et al. 2001. Three-cell interactions in T cell-mediated suppression? A mathematical analysis of its quantitative implications. J. Immunol. 166, 5356-5365.
-
(2001)
J. Immunol
, vol.166
, pp. 5356-5365
-
-
Leon, K.1
Perez, R.2
-
64
-
-
0028675006
-
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
-
Linsley, P.S., Greene, J.L., et al. 1994. Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors. Immunity 1, 793-801.
-
(1994)
Immunity
, vol.1
, pp. 793-801
-
-
Linsley, P.S.1
Greene, J.L.2
-
65
-
-
0033638003
-
On the dynamics of TCR:CD3 complex cell surface expression and downmodulation
-
Liu, H., Rhodes, M., et al. 2000. On the dynamics of TCR:CD3 complex cell surface expression and downmodulation. Immunity 13, 665-675.
-
(2000)
Immunity
, vol.13
, pp. 665-675
-
-
Liu, H.1
Rhodes, M.2
-
66
-
-
0032977676
-
A kinetic differentiation model for the action of altered TCR ligands
-
Lord, G.M., Lechler, R.I., et al. 1999. A kinetic differentiation model for the action of altered TCR ligands. Immunol. Today 20, 33-39.
-
(1999)
Immunol. Today
, vol.20
, pp. 33-39
-
-
Lord, G.M.1
Lechler, R.I.2
-
67
-
-
0028797801
-
CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes
-
Luescher, I.F., Vivier, E., et al. 1995. CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature 373, 353-356.
-
(1995)
Nature
, vol.373
, pp. 353-356
-
-
Luescher, I.F.1
Vivier, E.2
-
68
-
-
33845745287
-
Influence of human CD8 on antigen recognition by T-cell receptor-transduced cells
-
Lyons, G.E., Moore, T., et al. 2006. Influence of human CD8 on antigen recognition by T-cell receptor-transduced cells. Cancer Res. 66, 11455-11461.
-
(2006)
Cancer Res
, vol.66
, pp. 11455-11461
-
-
Lyons, G.E.1
Moore, T.2
-
69
-
-
0033593607
-
Differential signalling by variant ligands of the T cell receptor and the kinetic model of T cell activation
-
Madrenas, J. 1999. Differential signalling by variant ligands of the T cell receptor and the kinetic model of T cell activation. Life Sci. 64, 717-731.
-
(1999)
Life Sci
, vol.64
, pp. 717-731
-
-
Madrenas, J.1
-
70
-
-
0033199753
-
Binding energetics of T-cell receptors: Correlation with immunological consequences
-
Manning, T.C., and Kranz, D.M. 1999. Binding energetics of T-cell receptors: correlation with immunological consequences. Immunol. Today 20, 417-422.
-
(1999)
Immunol. Today
, vol.20
, pp. 417-422
-
-
Manning, T.C.1
Kranz, D.M.2
-
71
-
-
0030464365
-
Measurement of T-cell CD69 expression: A rapid and efficient means to assess mitogen- or antigen-induced proliferative capacity in normals
-
Mardiney, M., 3rd, Brown, M.R., et al. 1996. Measurement of T-cell CD69 expression: a rapid and efficient means to assess mitogen- or antigen-induced proliferative capacity in normals. Cytometry 26, 305-310.
-
(1996)
Cytometry
, vol.26
, pp. 305-310
-
-
Mardiney 3rd, M.1
Brown, M.R.2
-
72
-
-
0030738184
-
Interactions of TCRs with MHC-peptide complexes: A quantitative basis for mechanistic models
-
Margulies, D.H. 1997. Interactions of TCRs with MHC-peptide complexes: a quantitative basis for mechanistic models. Curr. Opin. Immunol. 9, 390-395.
-
(1997)
Curr. Opin. Immunol
, vol.9
, pp. 390-395
-
-
Margulies, D.H.1
-
73
-
-
28244452908
-
CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens
-
Marquez, M.E., Ellmeier, W., et al. 2005. CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens. J. Immunol. 175, 7388-7397.
-
(2005)
J. Immunol
, vol.175
, pp. 7388-7397
-
-
Marquez, M.E.1
Ellmeier, W.2
-
74
-
-
0032819133
-
CD69 and regulation of the immune function
-
Marzio, R., Mauel, J., et al. 1999. CD69 and regulation of the immune function. Immunopharmacol Immunotoxicol. 21, 565-582.
-
(1999)
Immunopharmacol Immunotoxicol
, vol.21
, pp. 565-582
-
-
Marzio, R.1
Mauel, J.2
-
75
-
-
0026345967
-
Low affinity interaction of peptide-MHC complexes with T cell receptors
-
Matsui, K., Boniface, J.J., et al. 1991. Low affinity interaction of peptide-MHC complexes with T cell receptors. Science 254, 1788-1791.
-
(1991)
Science
, vol.254
, pp. 1788-1791
-
-
Matsui, K.1
Boniface, J.J.2
-
76
-
-
0029063148
-
Kinetic proofreading in T-cell receptor signal transduction
-
McKeithan, T.W. 1995. Kinetic proofreading in T-cell receptor signal transduction. Proc. Natl. Acad. Sci. USA 92, 5042-5046.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5042-5046
-
-
McKeithan, T.W.1
-
77
-
-
0037310591
-
TCR reserve: A novel principle of CD4 T cell activation by weak ligands
-
McNeil, L.K., and Evavold, B.D. 2003. TCR reserve: a novel principle of CD4 T cell activation by weak ligands. J. Immunol. 170, 1224-1230.
-
(2003)
J. Immunol
, vol.170
, pp. 1224-1230
-
-
McNeil, L.K.1
Evavold, B.D.2
-
78
-
-
5444229324
-
+ T cell activation by dendritic cells in lymph nodes
-
+ T cell activation by dendritic cells in lymph nodes. J. Exp. Med. 200, 847-856.
-
(2004)
J. Exp. Med
, vol.200
, pp. 847-856
-
-
Miller, M.J.1
Safrina, O.2
-
79
-
-
0036885014
-
CD4 dimers constitute the functional component required for T cell activation
-
Moldovan, M.C., Yachou, A., et al. 2002. CD4 dimers constitute the functional component required for T cell activation. J. Immunol. 169, 6261-6268.
-
(2002)
J. Immunol
, vol.169
, pp. 6261-6268
-
-
Moldovan, M.C.1
Yachou, A.2
-
80
-
-
0035980059
-
The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain
-
Purbhoo, M.A., Boulter, J.M., et al. 2001. The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain. J. Biol. Chem. 276, 32786-32792.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 32786-32792
-
-
Purbhoo, M.A.1
Boulter, J.M.2
-
81
-
-
0035811008
-
Synaptic pattern formation during cellular recognition
-
Qi, S.Y., Groves, J.T., et al. 2001. Synaptic pattern formation during cellular recognition. Proc. Natl. Acad. Sci. USA 98, 6548-6553.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 6548-6553
-
-
Qi, S.Y.1
Groves, J.T.2
-
82
-
-
0029926145
-
Kinetic discrimination in T-cell activation
-
Rabinowitz, J.D., Beeson, C., et al. 1996. Kinetic discrimination in T-cell activation. Proc. Natl. Acad. Sci. USA 93, 1401-1405.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1401-1405
-
-
Rabinowitz, J.D.1
Beeson, C.2
-
83
-
-
0036898764
-
A temporal and spatial summation model for T-cell activation: Signal integration and antigen decoding
-
Rachmilewitz, J., and Lanzavecchia, A. 2002. A temporal and spatial summation model for T-cell activation: signal integration and antigen decoding. Trends Immunol. 23, 592-595.
-
(2002)
Trends Immunol
, vol.23
, pp. 592-595
-
-
Rachmilewitz, J.1
Lanzavecchia, A.2
-
84
-
-
0030472888
-
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding
-
Renard, V., Romero, P., et al. 1996. CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding. J. Exp. Med. 184, 2439-2444.
-
(1996)
J. Exp. Med
, vol.184
, pp. 2439-2444
-
-
Renard, V.1
Romero, P.2
-
85
-
-
0033953613
-
Modeling the interactions of a peptide-major histocompatibility class I ligand with its receptors. I. Recognition by two alpha beta T cell receptors
-
Rognan, D., Stryhn, A., et al. 2000. Modeling the interactions of a peptide-major histocompatibility class I ligand with its receptors. I. Recognition by two alpha beta T cell receptors. J. Comput. Aided Mol. Des. 14, 53-69.
-
(2000)
J. Comput. Aided Mol. Des
, vol.14
, pp. 53-69
-
-
Rognan, D.1
Stryhn, A.2
-
86
-
-
0034903068
-
The impact of duration versus extent of TCR occupancy on T cell activation: A revision of the kinetic proofreading model
-
Rosette, C., Werlen, G., et al. 2001. The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model. Immunity 15, 59-70.
-
(2001)
Immunity
, vol.15
, pp. 59-70
-
-
Rosette, C.1
Werlen, G.2
-
87
-
-
0032519331
-
Estimation of maximal affinities between T-cell receptors and MHC/peptide complexes
-
Salzmann, M., and Bachmann, M. F. 1998. Estimation of maximal affinities between T-cell receptors and MHC/peptide complexes. Mol. Immunol. 35, 65-71.
-
(1998)
Mol. Immunol
, vol.35
, pp. 65-71
-
-
Salzmann, M.1
Bachmann, M.F.2
-
88
-
-
0842326617
-
A logical analysis of the process of T cell activation: Different consequences depending on the state of CD28 engagement
-
Sarkar, A., and Franza, B.R. 2004. A logical analysis of the process of T cell activation: different consequences depending on the state of CD28 engagement. J. Theor. Biol. 226, 455-466.
-
(2004)
J. Theor. Biol
, vol.226
, pp. 455-466
-
-
Sarkar, A.1
Franza, B.R.2
-
89
-
-
0033118739
-
A kinetic basis for T cell receptor repertoire selection during an immune response
-
Savage, P.A., Boniface, J.J., et al. 1999. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity 10, 485-492.
-
(1999)
Immunity
, vol.10
, pp. 485-492
-
-
Savage, P.A.1
Boniface, J.J.2
-
90
-
-
0037120052
-
(+) T cells is amplified by prolonged T cell antigen receptor triggering
-
(+) T cells is amplified by prolonged T cell antigen receptor triggering. J. Exp. Med. 196, 793-803.
-
(2002)
J. Exp. Med
, vol.196
, pp. 793-803
-
-
Schrum, A.G.1
Turka, L.A.2
-
91
-
-
23844444069
-
T-cell activation and immunologic synapse
-
Shaw, A.S. 2005. T-cell activation and immunologic synapse. Immunol. Res. 32, 247-252.
-
(2005)
Immunol. Res
, vol.32
, pp. 247-252
-
-
Shaw, A.S.1
-
92
-
-
0027270369
-
Mathematical modeling of T-cell proliferation
-
Sidorov, I.A., and Romanyukha, A.A. 1993. Mathematical modeling of T-cell proliferation. Math Biosci. 115, 187-232.
-
(1993)
Math Biosci
, vol.115
, pp. 187-232
-
-
Sidorov, I.A.1
Romanyukha, A.A.2
-
93
-
-
0024441816
-
The interleukin 2 receptor
-
Smith, K.A. 1989. The interleukin 2 receptor. Annu. Rev. Cell Biol. 5, 397-425.
-
(1989)
Annu. Rev. Cell Biol
, vol.5
, pp. 397-425
-
-
Smith, K.A.1
-
94
-
-
0033737310
-
A mathematical analysis of TCR serial triggering and down-regulation
-
Sousa, J., and Carneiro, J. 2000. A mathematical analysis of TCR serial triggering and down-regulation. Eur. J. Immunol. 30, 3219-3227.
-
(2000)
Eur. J. Immunol
, vol.30
, pp. 3219-3227
-
-
Sousa, J.1
Carneiro, J.2
-
95
-
-
0035881574
-
+ T cells in vivo: Multiple thresholds in response to a constant level of antigen presentation
-
+ T cells in vivo: multiple thresholds in response to a constant level of antigen presentation. J. Immunol. 167, 2030-2039.
-
(2001)
J. Immunol
, vol.167
, pp. 2030-2039
-
-
Tanchot, C.1
Barber, D.L.2
-
96
-
-
33750744766
-
Is the activity of partially agonistic MHC:peptide ligands dependent on the quality of immunological help?
-
Uhlin, M., Masucci, M., et al. 2006. Is the activity of partially agonistic MHC:peptide ligands dependent on the quality of immunological help? Scand. J. Immunol. 64, 581-587.
-
(2006)
Scand. J. Immunol
, vol.64
, pp. 581-587
-
-
Uhlin, M.1
Masucci, M.2
-
97
-
-
0029037210
-
Serial triggering of many T-cell receptors by a few peptide-MHC complexes
-
Valitutti, S., Muller, S., et al. 1995. Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 375, 148-151.
-
(1995)
Nature
, vol.375
, pp. 148-151
-
-
Valitutti, S.1
Muller, S.2
-
98
-
-
0036915756
-
Do T cell receptors do it alone?
-
van der Merwe, P.A. 2002. Do T cell receptors do it alone? Nat. Immunol. 3, 1122-1123.
-
(2002)
Nat. Immunol
, vol.3
, pp. 1122-1123
-
-
van der Merwe, P.A.1
-
99
-
-
0031054242
-
CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics
-
van der Merwe, P.A., Bodian, D.L., et al. 1997. CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics. J. Exp. Med. 185, 393-403.
-
(1997)
J. Exp. Med
, vol.185
, pp. 393-403
-
-
van der Merwe, P.A.1
Bodian, D.L.2
-
100
-
-
0042971650
-
Molecular interactions mediating T cell antigen recognition
-
van der Merwe, P.A., and Davis, S.J. 2003. Molecular interactions mediating T cell antigen recognition. Annu. Rev. Immunol. 21, 659-684.
-
(2003)
Annu. Rev. Immunol
, vol.21
, pp. 659-684
-
-
van der Merwe, P.A.1
Davis, S.J.2
-
101
-
-
0028478132
-
The interaction between CD4 and MHC class II molecules and its effect on T cell function
-
Vignali, D.A. 1994. The interaction between CD4 and MHC class II molecules and its effect on T cell function. Behring Inst. Mitt. 94, 133-147.
-
(1994)
Behring Inst. Mitt
, vol.94
, pp. 133-147
-
-
Vignali, D.A.1
-
102
-
-
0032533461
-
+ memory T cells display broad heterogeneity in their activation threshold for cytokine synthesis
-
+ memory T cells display broad heterogeneity in their activation threshold for cytokine synthesis. J. Immunol. 161, 5284-5295.
-
(1998)
J. Immunol
, vol.161
, pp. 5284-5295
-
-
Waldrop, S.L.1
Davis, K.A.2
-
103
-
-
0037105625
-
Peptidic termini play a significant role in TCR recognition
-
Wang, B., Sharma, A., et al. 2002. Peptidic termini play a significant role in TCR recognition. J. Immunol. 169, 3137-3145.
-
(2002)
J. Immunol
, vol.169
, pp. 3137-3145
-
-
Wang, B.1
Sharma, A.2
-
104
-
-
33748452685
-
T-cell activation: A queuing theory analysis at low agonist density
-
Wedagedera, J.R., and Burroughs, N.J. 2006. T-cell activation: a queuing theory analysis at low agonist density. Biophys. J. 91, 1604-1618.
-
(2006)
Biophys. J
, vol.91
, pp. 1604-1618
-
-
Wedagedera, J.R.1
Burroughs, N.J.2
-
106
-
-
0035253576
-
A model to predict cell-mediated immune regulatory mechanisms during human infection with Mycobacterium tuberculosis
-
Wigginton, J.E., and Kirschner, D. 2001. A model to predict cell-mediated immune regulatory mechanisms during human infection with Mycobacterium tuberculosis. J. Immunol. 166, 1951-1967.
-
(2001)
J. Immunol
, vol.166
, pp. 1951-1967
-
-
Wigginton, J.E.1
Kirschner, D.2
-
107
-
-
0033577859
-
A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex
-
Williams, C.B., Engle, D.L., et al. 1999. A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex. J. Exp. Med. 189, 1531-1544.
-
(1999)
J. Exp. Med
, vol.189
, pp. 1531-1544
-
-
Williams, C.B.1
Engle, D.L.2
-
108
-
-
0035146577
-
Calculations show substantial serial engagement of T cell receptors
-
Wofsy, C., Coombs, D., et al. 2001. Calculations show substantial serial engagement of T cell receptors. Biophys. J. 80, 606-612.
-
(2001)
Biophys. J
, vol.80
, pp. 606-612
-
-
Wofsy, C.1
Coombs, D.2
-
109
-
-
0029006650
-
Ligand binding analysis of soluble interleukin-2 receptor complexes by surface plasmon resonance
-
Wu, Z., Johnson, K.W., et al. 1995. Ligand binding analysis of soluble interleukin-2 receptor complexes by surface plasmon resonance. J. Biol. Chem. 270, 16045-16051.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 16045-16051
-
-
Wu, Z.1
Johnson, K.W.2
-
110
-
-
0036346992
-
Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms
-
Xu, Z., and Weiss, A. 2002. Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms. Nat. Immunol. 3, 764-771.
-
(2002)
Nat. Immunol
, vol.3
, pp. 764-771
-
-
Xu, Z.1
Weiss, A.2
-
111
-
-
0036681543
-
(+) T cells by skin grafts via direct antigen presentation
-
(+) T cells by skin grafts via direct antigen presentation. J. Immunol. 169, 1270-1276.
-
(2002)
J. Immunol
, vol.169
, pp. 1270-1276
-
-
Zhai, Y.1
Shen, X.D.2
|