A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex

Journal of Experimental Medicine

Volumn 189, Issue 10, 1999, Pages 1531-1544

  Williams, Calvin B ^a   Engle, Deborah L ^a   Kersh, Gilbert J ^a   White, J Michael ^a   Allen, Paul M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Altered peptide ligand; Selection; T cell receptor; Thymocyte; Transgenic

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CELL SELECTION; CONTROLLED STUDY; HALF LIFE TIME; KINETICS; LIGAND BINDING; LONGEVITY; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; THYMOCYTE; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; HEMOGLOBINS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HYBRIDOMAS; KINETICS; LIGANDS; MICE; MICE, TRANSGENIC; MURAMIDASE; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL; SPLEEN; T-LYMPHOCYTES; THYMUS GLAND;

EID: 0033577859     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.10.1531     Document Type: Article

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