T-cell activation and immunologic synapse

Immunologic Research

Volumn 32, Issue 1-3, 2005, Pages 247-252

  Shaw, Andrey S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

14 3 3; CD2AP; Immunologic synapse; Kinase; Podocyte; T cell activation

Indexed keywords

CD2 ASSOCIATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

CHEMICAL ANALYSIS; CYTOSKELETON; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC DISORDER; HUMAN; KIDNEY DISEASE; KIDNEY FAILURE; MOLECULAR INTERACTION; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

14-3-3 PROTEINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CYTOSKELETAL PROTEINS; CYTOSKELETON; ENDOCYTOSIS; KIDNEY DISEASES; LYMPHOCYTE ACTIVATION; MAP KINASE SIGNALING SYSTEM; MICE; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PODOCYTES; PROTEINS; T-LYMPHOCYTES;

EID: 23844444069     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1385/IR:32:1-3:247     Document Type: Review

References (26)

1. Gauen LK, Zhu Y, Letourneur F, et al: Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif. Mol Cell Biol 1994;14:3729-3741.
2. Shaw AS, Amrein KE, Hammond C, Stern DF, Sefton BM, Rose JK: The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain. Cell 1989;59:627-636.
3. Shaw AS, Chalupny J, Whitney JA, et al: Short related sequences in the cytoplasmic domains of CD4 and CD8 mediate binding to the amino-terminal domain of the p56lck tyrosine protein kinase. Mol Cell Biol 1990;10:1853-1862.
4. Timson Gauen LK, Kong AN, Samelson LE, Shaw AS: p59fyn tyrosine kinase associates with multiple T-cell receptor subunits through its unique amino-terminal domain. Mol Cell Biol 1992;12:5438-5446.
5. Timson Gauen LK, Linder ME, Shaw AS: Multiple features of the p59fyn src homology 4 domain define a motif for immune-receptor tyrosine-based activation motif (ITAM) binding and for plasma membrane localization. J Cell Biol 1996;133:1007-1015.
6. Shenoy-Scaria AM, Gauen LK, Kwong J, Shaw AS, Lublin DM: Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl- phosphatidylinositol-anchored proteins. Mol Cell Biol 1993;13:6385-6392.
7. Bu JY, Shaw AS, Chan AC: Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance. Proc Natl Acad Sci USA 1995;92:5106-5110.
8. Shaw AS, Dustin ML: Making the T cell receptor go the distance: a topological view of T cell activation. Immunity 1997;6:361-369.
9. Dustin ML, Olszowy MW, Holdorf AD, et al: A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts. Cell 1998;94:667-677.
10. Grakoui A, Bromley SK, Sumen C, et al: The immunological synapse: a molecular machine controlling T cell activation. Science 1999;285:221-227.
11. Chakraborty AK, Dustin ML, Shaw AS: In silico models for cellular and molecular immunology: successes, promises and challenges. Nat Immunol 2003;4:933-936.
12. Lee KH, Dinner AR, Tu C, et al: The immunological synapse balances T cell receptor signaling and degradation. Science 2003;302:1218-1222.
13. Gout I, Middleton G, Adu J, et al: Negative regulation of PI 3-kinase by Ruk, a novel adaptor protein. EMBO J 2000;19:4015-4025.
14. Take H, Watanabe S, Takeda K, Yu ZX, Iwata N, Kajigaya S: Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl. Biochem Biophys Res Commun 2000;268:321-328.
15. Richard S, Yu D, Blumer KJ, et al: Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipids C gamma-1. Mol Cell Biol 1995;15:186-197.
16. Muslin AJ, Tanner JW, Allen PM, Shaw AS: Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine. Cell 1996;84:889-897.
17. Thorson JA, Yu LW, Hsu AL, et al: 14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity. Mol Cell Biol 1998;18:5229-5238.
18. Burack WR, Cheng AM, Shaw AS: Scaffolds, adaptors and linkers of TCR signaling: theory and practice. Curr Opin Immunol 2002;14:312-316.
19. Burack WR, Shaw AS: Signal transduction: hanging on a scaffold. Curr Opin Cell Biol 2000;12:211-216.
20. Nguyen A, Burack WR, Stock JL, et al: Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol Cell Biol 2002;22:3035-3045.
21. Kornfeld K, Hom DB, Horvitz HR: The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans. Cell 1995;83:903-913.
22. Therrien M, Chang HC, Solomon NM, Karim FD, Wassarman DA, Rubin GM: KSR, a novel protein kinase required for RAS signal transduction. Cell 1995;83:879-888.
23. Shih NY, Li J, Karpitskii V, et al: Congenital nephrotic syndrome in mice lacking CD2-associated protein. Science 1999;286:312-315.
24. Kim JM, Wu H, Green G, et al: CD-2 associated protein haploinsufficiency is linked to glomerular disease susceptibility. Science 2003;300:1298-1300.
25. Sallusto F, Cella M, Danieli C, Lanzavecchia A: Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class JJ compartment: downregulation by cytokines and bacterial products. J Exp Med 1995;182:389-400.
26. Araki N, Hatae T, Yamada T, Hirohashi S: Actinin-4 is preferentially involved in circular raffling and macropinocytosis in mouse macrophages: analysis by fluorescence ratio imaging. J Cell Sci 2000;113:3329-3340.