-
1
-
-
19344372271
-
Systems biology: Its practice and challenges
-
Aderem, A. (2005) Systems biology: its practice and challenges. Cell 121, 511-513.
-
(2005)
Cell
, vol.121
, pp. 511-513
-
-
Aderem, A.1
-
2
-
-
15944369290
-
ER stress signaling by regulated splicing: IRE1/HAC1/XBP1
-
Back, S. H., Schroder, M., Lee, K., Zhang, K. and Kaufman, R. J. (2005) ER stress signaling by regulated splicing: IRE1/HAC1/XBP1. Methods 35, 395-416.
-
(2005)
Methods
, vol.35
, pp. 395-416
-
-
Back, S.H.1
Schroder, M.2
Lee, K.3
Zhang, K.4
Kaufman, R.J.5
-
3
-
-
30344460667
-
The role of p97/Cdc48p in endoplasmic reticulum-associated degradation: From the immune system to yeast
-
Bar-Nun, S. (2005)The role of p97/Cdc48p in endoplasmic reticulum-associated degradation: from the immune system to yeast. Curr. Top. Microbiol. Immunol. 300, 95-125.
-
(2005)
Curr. Top. Microbiol. Immunol
, vol.300
, pp. 95-125
-
-
Bar-Nun, S.1
-
5
-
-
0035094262
-
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice
-
Bertolotti, A., Wang, X., Novoa, I., Jungreis, R., Schlessinger, K., Cho, J. H., West, A. B. and Ron, D. (2001) Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice. J. Clin. Invest. 107, 585-593.
-
(2001)
J. Clin. Invest
, vol.107
, pp. 585-593
-
-
Bertolotti, A.1
Wang, X.2
Novoa, I.3
Jungreis, R.4
Schlessinger, K.5
Cho, J.H.6
West, A.B.7
Ron, D.8
-
6
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
Bertolotti, A., Zhang, Y., Hendershot, L. M., Harding, H. P. and Ron, D. (2000) Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat. Cell Biol. 2, 326-332.
-
(2000)
Nat. Cell Biol
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
7
-
-
27144458505
-
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
-
Bi, M., Naczki, C., Koritzinsky, M., Fels, D., Blais, J., Hu, N., Harding, H., Novoa, I., Varia, M., Raleigh, J., Scheuner, D., Kaufman, R. J., Bell, J., Ron, D., Wouters, B. G. and Koumenis, C. (2005) ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. EMBO J. 24, 3470-3481.
-
(2005)
EMBO J
, vol.24
, pp. 3470-3481
-
-
Bi, M.1
Naczki, C.2
Koritzinsky, M.3
Fels, D.4
Blais, J.5
Hu, N.6
Harding, H.7
Novoa, I.8
Varia, M.9
Raleigh, J.10
Scheuner, D.11
Kaufman, R.J.12
Bell, J.13
Ron, D.14
Wouters, B.G.15
Koumenis, C.16
-
8
-
-
0029555913
-
Unidirectional and bidirectional protein traffic across membranes
-
Blobel, G. (1995) Unidirectional and bidirectional protein traffic across membranes. Cold Spring Harb. Symp. Quant. Biol. 60, 1-10.
-
(1995)
Cold Spring Harb. Symp. Quant. Biol
, vol.60
, pp. 1-10
-
-
Blobel, G.1
-
9
-
-
33645735557
-
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
-
Boeddrich, A., Gaumer, S., Haacke, A., Tzvetkov, N., Albrecht, M., Evert, B. O., Muller, E. C., Lurz, R., Breuer, P., Schugardt, N., Plassmann, S., Xu, K., Warrick, J. M., Suopanki, J., Wullner, U., Frank, R., Hartl, U. F., Bonini, N. M. and Wanker, E. E. (2006) An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO J. 25, 1547-1558.
-
(2006)
EMBO J
, vol.25
, pp. 1547-1558
-
-
Boeddrich, A.1
Gaumer, S.2
Haacke, A.3
Tzvetkov, N.4
Albrecht, M.5
Evert, B.O.6
Muller, E.C.7
Lurz, R.8
Breuer, P.9
Schugardt, N.10
Plassmann, S.11
Xu, K.12
Warrick, J.M.13
Suopanki, J.14
Wullner, U.15
Frank, R.16
Hartl, U.F.17
Bonini, N.M.18
Wanker, E.E.19
-
10
-
-
0032441479
-
Ubiquitin and the control of protein fate in the secretory and endocytic pathways
-
Bonifacino, J. S. andWeissman, A. M. (1998) Ubiquitin and the control of protein fate in the secretory and endocytic pathways. Annu. Rev. Cell Dev. Biol. 14, 19-57.
-
(1998)
Annu. Rev. Cell Dev. Biol
, vol.14
, pp. 19-57
-
-
Bonifacino, J.S.1
Weissman, A.M.2
-
11
-
-
0037417334
-
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
-
Breckenridge, D. G., Stojanovic, M., Marcellus, R. C. and Shore, G. C. (2003) Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J. Cell Biol. 160, 1115-1127.
-
(2003)
J. Cell Biol
, vol.160
, pp. 1115-1127
-
-
Breckenridge, D.G.1
Stojanovic, M.2
Marcellus, R.C.3
Shore, G.C.4
-
12
-
-
33646127577
-
Molecular chaperones and protein quality control
-
Bukau, B., Weissman, J. and Horwich, A. (2006) Molecular chaperones and protein quality control. Cell 125, 443-451.
-
(2006)
Cell
, vol.125
, pp. 443-451
-
-
Bukau, B.1
Weissman, J.2
Horwich, A.3
-
13
-
-
0035478934
-
Dissecting glycoprotein quality control in the secretory pathway
-
Cabral, C. M., Liu, Y. and Sifers, R. N. (2001) Dissecting glycoprotein quality control in the secretory pathway. Trends Biochem. Sci. 26, 619-624.
-
(2001)
Trends Biochem. Sci
, vol.26
, pp. 619-624
-
-
Cabral, C.M.1
Liu, Y.2
Sifers, R.N.3
-
14
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon, M., Zeng, H., Urano, F., Till, J. H., Hubbard, S. R., Harding, H. P., Clark, S. G. and Ron, D. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415, 92-96.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
15
-
-
0017056666
-
The role of organelles in the chemical modification of the primary translation products of secretory proteins
-
Campbell, P. N. and Blobel, G. (1976) The role of organelles in the chemical modification of the primary translation products of secretory proteins. FEBS Lett. 72, 215-226.
-
(1976)
FEBS Lett
, vol.72
, pp. 215-226
-
-
Campbell, P.N.1
Blobel, G.2
-
16
-
-
0036183603
-
Coordinated action of protein tyrosine phosphatases in insulin signal transduction
-
Cheng, A., Dube, N., Gu, F. andTremblay, M. L. (2002) Coordinated action of protein tyrosine phosphatases in insulin signal transduction. Eur. J. Biochem. 269, 1050-1059.
-
(2002)
Eur. J. Biochem
, vol.269
, pp. 1050-1059
-
-
Cheng, A.1
Dube, N.2
Gu, F.3
Tremblay, M.L.4
-
17
-
-
0035253122
-
The endoplasmic reticulum: Integration of protein folding, quality control, signaling and degradation
-
Chevet, E., Cameron, P. H., Pelletier, M. F., Thomas, D. Y. and Bergeron, J. J. (2001) The endoplasmic reticulum: integration of protein folding, quality control, signaling and degradation. Curr. Opin. Struct. Biol. 11, 120-124.
-
(2001)
Curr. Opin. Struct. Biol
, vol.11
, pp. 120-124
-
-
Chevet, E.1
Cameron, P.H.2
Pelletier, M.F.3
Thomas, D.Y.4
Bergeron, J.J.5
-
18
-
-
0033210209
-
Calnexin family members as modulators of genetic diseases
-
Chevet, E., Jakob, C. A., Thomas, D. Y. and Bergeron, J. J. (1999a). Calnexin family members as modulators of genetic diseases. Semin Cell Dev. Biol. 10, 473-480.
-
(1999)
Semin Cell Dev. Biol
, vol.10
, pp. 473-480
-
-
Chevet, E.1
Jakob, C.A.2
Thomas, D.Y.3
Bergeron, J.J.4
-
19
-
-
0033168581
-
Phosphorylation by CK2 and MAPK enhances calnexin association with ribosomes
-
Chevet, E., Wong, H. N., Gerber, D., Cochet, C., Fazel, A., Cameron, P. H., Gushue, J. N., Thomas, D. Y. and Bergeron, J. J. (1999b). Phosphorylation by CK2 and MAPK enhances calnexin association with ribosomes. EMBO J. 18, 3655-3666.
-
(1999)
EMBO J
, vol.18
, pp. 3655-3666
-
-
Chevet, E.1
Wong, H.N.2
Gerber, D.3
Cochet, C.4
Fazel, A.5
Cameron, P.H.6
Gushue, J.N.7
Thomas, D.Y.8
Bergeron, J.J.9
-
20
-
-
27544433981
-
An E-MAP of the ER
-
Conibear, E. (2005) An E-MAP of the ER. Cell 123, 366-368.
-
(2005)
Cell
, vol.123
, pp. 366-368
-
-
Conibear, E.1
-
21
-
-
85063817307
-
Protein folding as post-translational regulation: Evolution of a mechanism for controlled plasma membrane expression of a GPCR
-
Conn, P. M., Knollman, P. E., Brothers, S. P. and Janovick, J. A. (2006) Protein folding as post-translational regulation: evolution of a mechanism for controlled plasma membrane expression of a GPCR. Mol. Endocrinol. 12, 161-171.
-
(2006)
Mol. Endocrinol
, vol.12
, pp. 161-171
-
-
Conn, P.M.1
Knollman, P.E.2
Brothers, S.P.3
Janovick, J.A.4
-
22
-
-
30044432596
-
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
-
Credle, J. J., Finer-Moore, J. S., Papa, F. R., Stroud, R. M. and Walter, P. (2005) On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc. Natl Acad. Sci. U. S. A. 102, 18773-18784.
-
(2005)
Proc. Natl Acad. Sci. U.S.A
, vol.102
, pp. 18773-18784
-
-
Credle, J.J.1
Finer-Moore, J.S.2
Papa, F.R.3
Stroud, R.M.4
Walter, P.5
-
23
-
-
2442542312
-
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
-
Cullinan, S. B. and Diehl, J. A. (2004) PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J. Biol. Chem. 279, 20108-20117.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 20108-20117
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
24
-
-
29244462498
-
Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway
-
Cullinan, S. B. and Diehl, J. A. (2006) Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway. Int. J. Biochem. Cell Biol. 38, 317-332.
-
(2006)
Int. J. Biochem. Cell Biol
, vol.38
, pp. 317-332
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
25
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan, S. B., Zhang, D., Hannink, M., Arvisais, E., Kaufman, R. J. and Diehl, J. A. (2003) Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol. Cell. Biol. 23, 7198-7209.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
26
-
-
33847042606
-
Calnexin-dependent regulation of tunicamycin-induced apoptosis in breast carcinoma MCF-7 cells
-
Delom, F., Emadali, A., Cocolakis, E., Lebrun, J. J., Nantel, A. and Chevet, E. (2007) Calnexin-dependent regulation of tunicamycin-induced apoptosis in breast carcinoma MCF-7 cells. Cell Death Differ. 14(3), 586-596.
-
(2007)
Cell Death Differ
, vol.14
, Issue.3
, pp. 586-596
-
-
Delom, F.1
Emadali, A.2
Cocolakis, E.3
Lebrun, J.J.4
Nantel, A.5
Chevet, E.6
-
27
-
-
0037162451
-
Association of calnexin with mutant peripheral myelin protein-22 ex vivo: A basis for "gain-of-function" ER diseases
-
Dickson, K. M., Bergeron, J. J., Shames, I., Colby, J., Nguyen, D. T., Chevet, E., Thomas, D. Y. and Snipes, G. J. (2002) Association of calnexin with mutant peripheral myelin protein-22 ex vivo: a basis for "gain-of-function" ER diseases. Proc. Natl Acad. Sci. USA 99, 9852-9857.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 9852-9857
-
-
Dickson, K.M.1
Bergeron, J.J.2
Shames, I.3
Colby, J.4
Nguyen, D.T.5
Chevet, E.6
Thomas, D.Y.7
Snipes, G.J.8
-
28
-
-
0042691818
-
Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis
-
Doss-Pepe, E. W., Stenroos, E. S., Johnson, W. G. and Madura, K. (2003) Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis. Mol. Cell Biol. 23, 6469-6483.
-
(2003)
Mol. Cell Biol
, vol.23
, pp. 6469-6483
-
-
Doss-Pepe, E.W.1
Stenroos, E.S.2
Johnson, W.G.3
Madura, K.4
-
29
-
-
0037336295
-
Quality control in the endoplasmic reticulum
-
Ellgaard, L. and Helenius, A. (2003) Quality control in the endoplasmic reticulum. Nat. Rev. Mol. Cell Biol. 4, 181-191.
-
(2003)
Nat. Rev. Mol. Cell Biol
, vol.4
, pp. 181-191
-
-
Ellgaard, L.1
Helenius, A.2
-
30
-
-
0024337857
-
Protein disulfide isomerase: Multiple roles in the modification of nascent secretory proteins
-
Freedman, R. B. (1989) Protein disulfide isomerase: multiple roles in the modification of nascent secretory proteins. Cell 57, 1069-1072.
-
(1989)
Cell
, vol.57
, pp. 1069-1072
-
-
Freedman, R.B.1
-
31
-
-
18044365052
-
Systems Biology-an interdisciplinary approach
-
Friboulet, A. and Thomas, D. (2005) Systems Biology-an interdisciplinary approach. Biosens. Bioelectron. 20, 2404-2407.
-
(2005)
Biosens. Bioelectron
, vol.20
, pp. 2404-2407
-
-
Friboulet, A.1
Thomas, D.2
-
32
-
-
0041699786
-
The ERATO Systems BiologyWorkbench and Systems Biology Markup Language: An integrated environment and standardization for systems biology
-
Funahashi, A. (2003) [The ERATO Systems BiologyWorkbench and Systems Biology Markup Language: an integrated environment and standardization for systems biology]. Tanpakushitsu Kakusan Koso 48, 810-816.
-
(2003)
Tanpakushitsu Kakusan Koso
, vol.48
, pp. 810-816
-
-
Funahashi, A.1
-
33
-
-
0033152626
-
Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway
-
Gonzalez, T. N., Sidrauski, C., Dorfler, S. and Walter, P. (1999) Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. EMBO J. 18, 3119-3132.
-
(1999)
EMBO J
, vol.18
, pp. 3119-3132
-
-
Gonzalez, T.N.1
Sidrauski, C.2
Dorfler, S.3
Walter, P.4
-
34
-
-
9644303176
-
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress
-
Gu, F., Nguyen, D. T., Stuible, M., Dube, N., Tremblay, M. L. and Chevet, E. (2004) Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress. J. Biol. Chem. 279, 49689-49693.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 49689-49693
-
-
Gu, F.1
Nguyen, D.T.2
Stuible, M.3
Dube, N.4
Tremblay, M.L.5
Chevet, E.6
-
35
-
-
1642506314
-
On systems thinking, systems biology, and the in silico plant
-
Hammer, G. L., Sinclair, T. R., Chapman, S. C. and van Oosterom, E. (2004) On systems thinking, systems biology, and the in silico plant. Plant Physiol. 134, 909-911.
-
(2004)
Plant Physiol
, vol.134
, pp. 909-911
-
-
Hammer, G.L.1
Sinclair, T.R.2
Chapman, S.C.3
van Oosterom, E.4
-
36
-
-
0034968330
-
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/-mice reveals a role for translational control in secretory cell survival
-
Harding, H. P., Zeng, H., Zhang, Y., Jungries, R., Chung, P., Plesken, H., Sabatini, D. D. and Ron, D. (2001) Diabetes mellitus and exocrine pancreatic dysfunction in perk-/-mice reveals a role for translational control in secretory cell survival. Mol. Cell. 7, 1153-1163.
-
(2001)
Mol. Cell
, vol.7
, pp. 1153-1163
-
-
Harding, H.P.1
Zeng, H.2
Zhang, Y.3
Jungries, R.4
Chung, P.5
Plesken, H.6
Sabatini, D.D.7
Ron, D.8
-
37
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmicreticulum-resident kinase
-
Harding, H. P., Zhang, Y. and Ron, D. (1999) Protein translation and folding are coupled by an endoplasmicreticulum-resident kinase. Nature 397, 271-274.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
38
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding, H. P., Zhang, Y., Zeng, H., Novoa, I., Lu, P. D., Calfon, M., Sadri, N., Yun, C., Popko, B., Paules, R., Stojdl, D. F., Bell, J. C., Hettmann, T., Leiden, J. M. and Ron, D. (2003)An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 11, 619-633.
-
(2003)
Mol Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
Stojdl, D.F.11
Bell, J.C.12
Hettmann, T.13
Leiden, J.M.14
Ron, D.15
-
39
-
-
0032693671
-
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
-
Haze, K., Yoshida, H., Yanagi, H., Yura, T. and Mori, K. (1999) Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol. Biol. Cell 10, 3787-3799.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3787-3799
-
-
Haze, K.1
Yoshida, H.2
Yanagi, H.3
Yura, T.4
Mori, K.5
-
40
-
-
21744447192
-
The glycan code of the endoplasmic reticulum: Asparagine-linked carbohydrates as protein maturation and quality-control tags
-
Hebert, D. N., Garman, S. C. and Molinari, M. (2005) The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags. Trends Cell. Biol. 15, 364-370.
-
(2005)
Trends Cell. Biol
, vol.15
, pp. 364-370
-
-
Hebert, D.N.1
Garman, S.C.2
Molinari, M.3
-
41
-
-
0035937505
-
Intracellular functions of N-linked glycans
-
Helenius, A. and Aebi, M. (2001) Intracellular functions of N-linked glycans. Science 291, 2364-2369.
-
(2001)
Science
, vol.291
, pp. 2364-2369
-
-
Helenius, A.1
Aebi, M.2
-
42
-
-
3943059566
-
Roles of N-linked glycans in the endoplasmic reticulum
-
Helenius, A. and Aebi, M. (2004) Roles of N-linked glycans in the endoplasmic reticulum. Annu. Rev. Biochem. 73, 1019-1049.
-
(2004)
Annu. Rev. Biochem
, vol.73
, pp. 1019-1049
-
-
Helenius, A.1
Aebi, M.2
-
43
-
-
0029890917
-
Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants
-
Hendershot, L., Wei, J., Gaut, J., Melnick, J., Aviel, S. and Argon, Y. (1996) Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants. Proc. Natl Acad. Sci. USA 93, 5269-5274.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 5269-5274
-
-
Hendershot, L.1
Wei, J.2
Gaut, J.3
Melnick, J.4
Aviel, S.5
Argon, Y.6
-
44
-
-
33646237823
-
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha
-
Hetz, C., Bernasconi, P., Fisher, J., Lee, A. H., Bassik, M. C., Antonsson, B., Brandt, G. S., Iwakoshi, N. N., Schinzel, A., Glimcher, L. H. and Korsmeyer, S. J. (2006) Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha. Science 312, 572-576.
-
(2006)
Science
, vol.312
, pp. 572-576
-
-
Hetz, C.1
Bernasconi, P.2
Fisher, J.3
Lee, A.H.4
Bassik, M.C.5
Antonsson, B.6
Brandt, G.S.7
Iwakoshi, N.N.8
Schinzel, A.9
Glimcher, L.H.10
Korsmeyer, S.J.11
-
45
-
-
28244499949
-
Accumulation of mutant alpha1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and-12, NFkappaB, and BAP31 but not the unfolded protein response
-
Hidvegi, T., Schmidt, B. Z., Hale, P. and Perlmutter, D. H. (2005)Accumulation of mutant alpha1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and-12, NFkappaB, and BAP31 but not the unfolded protein response. J. Biol. Chem. 280, 39002-39015.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 39002-39015
-
-
Hidvegi, T.1
Schmidt, B.Z.2
Hale, P.3
Perlmutter, D.H.4
-
46
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
Hollien, J. and Weissman, J. S. (2006) Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313, 52-53.
-
(2006)
Science
, vol.313
, pp. 52-53
-
-
Hollien, J.1
Weissman, J.S.2
-
47
-
-
33744958957
-
Calcium-sensing receptor ubiquitination and degradation mediated by the E3 ubiquitin ligase dorfin
-
Huang, Y., Niwa, J., Sobue, G. and Breitwieser, G. E. (2006) Calcium-sensing receptor ubiquitination and degradation mediated by the E3 ubiquitin ligase dorfin. J. Biol. Chem. 281, 11610-11617.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 11610-11617
-
-
Huang, Y.1
Niwa, J.2
Sobue, G.3
Breitwieser, G.E.4
-
48
-
-
0035147411
-
Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress
-
Iwawaki, T., Hosoda, A., Okuda, T., Kamigori, Y., Nomura-Furuwatari, C., Kimata, Y., Tsuru, A. and Kohno, K. (2001) Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress. Nat. Cell Biol. 3, 158-164.
-
(2001)
Nat. Cell Biol
, vol.3
, pp. 158-164
-
-
Iwawaki, T.1
Hosoda, A.2
Okuda, T.3
Kamigori, Y.4
Nomura-Furuwatari, C.5
Kimata, Y.6
Tsuru, A.7
Kohno, K.8
-
49
-
-
0035229307
-
Lectins of the ER quality control machinery
-
Jakob, C. A., Chevet, E., Thomas, D. Y. and Bergeron, J. J. (2001) Lectins of the ER quality control machinery. Results Probl. Cell Differ. 33, 1-17.
-
(2001)
Results Probl. Cell Differ
, vol.33
, pp. 1-17
-
-
Jakob, C.A.1
Chevet, E.2
Thomas, D.Y.3
Bergeron, J.J.4
-
50
-
-
0037287977
-
Endoplasmic reticulum-associated protein degradation
-
Jarosch, E., Lenk, U. and Sommer, T. (2003) Endoplasmic reticulum-associated protein degradation. Int. Rev. Cytol. 223, 39-81.
-
(2003)
Int. Rev. Cytol
, vol.223
, pp. 39-81
-
-
Jarosch, E.1
Lenk, U.2
Sommer, T.3
-
51
-
-
0033258544
-
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
-
Katayama, T., Imaizumi, K., Sato, N., Miyoshi, K., Kudo, T., Hitomi, J., Morihara, T., Yoneda, T., Gomi, F., Mori, Y., Nakano, Y., Takeda, J., Tsuda, T., Itoyama, Y., Murayama, O., Takashima, A., St George-Hyslop, P., Takeda, M. and Tohyama, M. (1999) Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat. Cell Biol. 1, 479-485.
-
(1999)
Nat. Cell Biol
, vol.1
, pp. 479-485
-
-
Katayama, T.1
Imaizumi, K.2
Sato, N.3
Miyoshi, K.4
Kudo, T.5
Hitomi, J.6
Morihara, T.7
Yoneda, T.8
Gomi, F.9
Mori, Y.10
Nakano, Y.11
Takeda, J.12
Tsuda, T.13
Itoyama, Y.14
Murayama, O.15
Takashima, A.16
St George-Hyslop, P.17
Takeda, M.18
Tohyama, M.19
-
52
-
-
1542304646
-
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
-
Kebache, S., Cardin, E., Nguyen, D. T., Chevet, E. and Larose, L. (2004) Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation. J. Biol. Chem. 279, 9662-9671.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 9662-9671
-
-
Kebache, S.1
Cardin, E.2
Nguyen, D.T.3
Chevet, E.4
Larose, L.5
-
53
-
-
0034308201
-
Protein tyrosine phosphatase-1B in diabetes
-
Kennedy, B. P. and Ramachandran, C. (2000) Protein tyrosine phosphatase-1B in diabetes. Biochem. Pharmacol. 60, 877-883.
-
(2000)
Biochem. Pharmacol
, vol.60
, pp. 877-883
-
-
Kennedy, B.P.1
Ramachandran, C.2
-
54
-
-
0037079054
-
Computational systems biology
-
Kitano, H. (2002a). Computational systems biology. Nature 420, 206-210.
-
(2002)
Nature
, vol.420
, pp. 206-210
-
-
Kitano, H.1
-
55
-
-
0036941857
-
Looking beyond the details: A rise in system-oriented approaches in genetics and molecular biology
-
Kitano, H. (2002b). Looking beyond the details: a rise in system-oriented approaches in genetics and molecular biology. Curr. Genet. 41, 1-10.
-
(2002)
Curr. Genet
, vol.41
, pp. 1-10
-
-
Kitano, H.1
-
56
-
-
0036500993
-
Systems biology: A brief overview
-
Kitano, H. (2002c). Systems biology: a brief overview. Science 295, 1662-1664.
-
(2002)
Science
, vol.295
, pp. 1662-1664
-
-
Kitano, H.1
-
57
-
-
0042701552
-
Introductions to systems biology
-
Kitano, H. (2003) [Introductions to systems biology]. Tanpakushitsu Kakusan Koso 48, 789-793.
-
(2003)
Tanpakushitsu Kakusan Koso
, vol.48
, pp. 789-793
-
-
Kitano, H.1
-
58
-
-
33746927955
-
International alliances for quantitative modeling in systems biology
-
Kitano, H. (2005) International alliances for quantitative modeling in systems biology. Mol. Syst. Biol. 1, 2005 0007.
-
(2005)
Mol. Syst. Biol
, vol.1
-
-
Kitano, H.1
-
59
-
-
3142587059
-
Protein folding and quality control in the endoplasmic reticulum
-
Kleizen, B. and Braakman, I. (2004) Protein folding and quality control in the endoplasmic reticulum. Curr. Opin. Cell Biol. 16, 343-349.
-
(2004)
Curr. Opin. Cell Biol
, vol.16
, pp. 343-349
-
-
Kleizen, B.1
Braakman, I.2
-
60
-
-
0041703031
-
The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: Elucidation by GADD34-deficient mice
-
Kojima, E., Takeuchi, A., Haneda, M., Yagi, A., Hasegawa, T., Yamaki, K., Takeda, K., Akira, S., Shimokata, K. and Isobe, K. (2003) The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice. FASEB J. 17, 1573-1575.
-
(2003)
FASEB J
, vol.17
, pp. 1573-1575
-
-
Kojima, E.1
Takeuchi, A.2
Haneda, M.3
Yagi, A.4
Hasegawa, T.5
Yamaki, K.6
Takeda, K.7
Akira, S.8
Shimokata, K.9
Isobe, K.10
-
61
-
-
0035937721
-
Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response
-
Kokame, K., Kato, H. and Miyata, T. (2001) Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response. J. Biol. Chem. 276, 9199-9205.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 9199-9205
-
-
Kokame, K.1
Kato, H.2
Miyata, T.3
-
62
-
-
0032321747
-
Protein N-glycosylation: Molecular genetics and functional significance
-
Kukuruzinska, M. A. and Lennon, K. (1998) Protein N-glycosylation: molecular genetics and functional significance. Crit. Rev. Oral Biol. Med. 9, 415-448.
-
(1998)
Crit. Rev. Oral Biol. Med
, vol.9
, pp. 415-448
-
-
Kukuruzinska, M.A.1
Lennon, K.2
-
63
-
-
19344374214
-
IRE1-independent gain control of the unfolded protein response
-
Leber, J. H., Bernales, S. and Walter, P. (2004) IRE1-independent gain control of the unfolded protein response. PLoS Biol. 2, E235.
-
(2004)
PLoS Biol
, vol.2
-
-
Leber, J.H.1
Bernales, S.2
Walter, P.3
-
64
-
-
0037203547
-
Modulation of life and death by the tumor necrosis factor receptor-associated factors (TRAFs)
-
Lee, N. K. and Lee, S. Y. (2002) Modulation of life and death by the tumor necrosis factor receptor-associated factors (TRAFs). J. Biochem. Mol. Biol. 35, 61-66.
-
(2002)
J. Biochem. Mol. Biol
, vol.35
, pp. 61-66
-
-
Lee, N.K.1
Lee, S.Y.2
-
65
-
-
33645141853
-
ER stress and neurodegenerative diseases
-
Lindholm, D., Wootz, H. and Korhonen, L. (2006) ER stress and neurodegenerative diseases. Cell Death Differ. 13, 385-392.
-
(2006)
Cell Death Differ
, vol.13
, pp. 385-392
-
-
Lindholm, D.1
Wootz, H.2
Korhonen, L.3
-
66
-
-
0018883281
-
Early events in the biosynthesis of secretory and membrane proteins: The signal hypothesis
-
Lingappa, V. R. and Blobel, G. (1980) Early events in the biosynthesis of secretory and membrane proteins: the signal hypothesis. Recent Prog. Horm. Res. 36, 451-475.
-
(1980)
Recent Prog. Horm. Res
, vol.36
, pp. 451-475
-
-
Lingappa, V.R.1
Blobel, G.2
-
67
-
-
0030469215
-
Polypeptide translocation machinery of the yeast endoplasmic reticulum
-
Lyman, S. K. and Schekman, R. (1996) Polypeptide translocation machinery of the yeast endoplasmic reticulum. Experientia 52, 1042-1049.
-
(1996)
Experientia
, vol.52
, pp. 1042-1049
-
-
Lyman, S.K.1
Schekman, R.2
-
68
-
-
0036314984
-
Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response
-
Ma, Y., Brewer, J. W., Diehl, J. A. and Hendershot, L. M. (2002) Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response. J. Mol. Biol. 318, 1351-1365.
-
(2002)
J. Mol. Biol
, vol.318
, pp. 1351-1365
-
-
Ma, Y.1
Brewer, J.W.2
Diehl, J.A.3
Hendershot, L.M.4
-
69
-
-
18744382408
-
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha
-
Marcu, M. G., Doyle, M., Bertolotti, A., Ron, D., Hendershot, L. and Neckers, L. (2002) Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha. Mol. Cell. Biol. 22, 8506-8513.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 8506-8513
-
-
Marcu, M.G.1
Doyle, M.2
Bertolotti, A.3
Ron, D.4
Hendershot, L.5
Neckers, L.6
-
70
-
-
30344460668
-
Recognition and delivery ofERADsubstrates to the proteasome and alternative paths for cell survival
-
McCracken, A. A. and Brodsky, J. L. (2005) Recognition and delivery ofERADsubstrates to the proteasome and alternative paths for cell survival. Curr. Top Microbiol. Immunol. 300, 17-40.
-
(2005)
Curr. Top Microbiol. Immunol
, vol.300
, pp. 17-40
-
-
McCracken, A.A.1
Brodsky, J.L.2
-
71
-
-
23444461901
-
Advances in synthetic biology: On the path from prototypes to applications
-
McDaniel, R. and Weiss, R. (2005) Advances in synthetic biology: on the path from prototypes to applications. Curr. Opin. Biotechnol. 16, 476-483.
-
(2005)
Curr. Opin. Biotechnol
, vol.16
, pp. 476-483
-
-
McDaniel, R.1
Weiss, R.2
-
72
-
-
23144451257
-
ERAD: The long road to destruction
-
Meusser, B., Hirsch, C., Jarosch, E. and Sommer, T. (2005) ERAD: the long road to destruction. Nat, Cell, Biol, 7, 766-772.
-
(2005)
Nat, Cell, Biol
, vol.7
, pp. 766-772
-
-
Meusser, B.1
Hirsch, C.2
Jarosch, E.3
Sommer, T.4
-
73
-
-
33646267694
-
Conformational diseases and ER stress-mediated cell death: Apoptotic cell death and autophagic cell death
-
Momoi, T. (2006) Conformational diseases and ER stress-mediated cell death: apoptotic cell death and autophagic cell death. Curr. Mol. Med. 6, 111-118.
-
(2006)
Curr. Mol. Med
, vol.6
, pp. 111-118
-
-
Momoi, T.1
-
74
-
-
0027305620
-
Atransmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
-
Mori, K., Ma, W., Gething, M. J. and Sambrook, J. (1993)Atransmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 74, 743-756.
-
(1993)
Cell
, vol.74
, pp. 743-756
-
-
Mori, K.1
Ma, W.2
Gething, M.J.3
Sambrook, J.4
-
75
-
-
2542488276
-
Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum
-
Nadanaka, S., Yoshida, H., Kano, F., Murata, M. and Mori, K. (2004) Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum. Mol. Biol. Cell. 15, 2537-2548.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 2537-2548
-
-
Nadanaka, S.1
Yoshida, H.2
Kano, F.3
Murata, M.4
Mori, K.5
-
76
-
-
33645114907
-
Absence of typical unfolded protein response in primary cultured cystic fibrosis airway epithelial cells
-
Nanua, S., Sajjan, U., Keshavjee, S. and Hershenson, M. B. (2006) Absence of typical unfolded protein response in primary cultured cystic fibrosis airway epithelial cells. Biochem. Biophys. Res. Commun. 343, 135-143.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.343
, pp. 135-143
-
-
Nanua, S.1
Sajjan, U.2
Keshavjee, S.3
Hershenson, M.B.4
-
77
-
-
0030705234
-
p28 Bap31, a Bcl-2/Bcl-XL-and procaspase-8-associated protein in the endoplasmic reticulum
-
Ng, F. W., Nguyen, M., Kwan, T., Branton, P. E., Nicholson, D. W., Cromlish, J. A. and Shore, G. C. (1997) p28 Bap31, a Bcl-2/Bcl-XL-and procaspase-8-associated protein in the endoplasmic reticulum. J. Cell Biol. 139, 327-338.
-
(1997)
J. Cell Biol
, vol.139
, pp. 327-338
-
-
Ng, F.W.1
Nguyen, M.2
Kwan, T.3
Branton, P.E.4
Nicholson, D.W.5
Cromlish, J.A.6
Shore, G.C.7
-
78
-
-
0033816610
-
Caspase-resistant BAP31 inhibits fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria
-
Nguyen, M., Breckenridge, D. G., Ducret, A. and Shore, G. C. (2000) Caspase-resistant BAP31 inhibits fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria. Mol. Cell. Biol. 20, 6731-6740.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 6731-6740
-
-
Nguyen, M.1
Breckenridge, D.G.2
Ducret, A.3
Shore, G.C.4
-
79
-
-
4344598305
-
Nck-dependent activation of extracellular signalregulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress
-
Nguyen, D. T., Kebache, S., Fazel, A., Wong, H. N., Jenna, S., Emadali, A., Lee, E. H., Bergeron, J. J., Kaufman, R. J., Larose, L. and Chevet, E. (2004) Nck-dependent activation of extracellular signalregulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress. Mol. Biol. Cell. 15, 4248-4260.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 4248-4260
-
-
Nguyen, D.T.1
Kebache, S.2
Fazel, A.3
Wong, H.N.4
Jenna, S.5
Emadali, A.6
Lee, E.H.7
Bergeron, J.J.8
Kaufman, R.J.9
Larose, L.10
Chevet, E.11
-
80
-
-
23644433913
-
Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease
-
Niwa, M., Patil, C. K., DeRisi, J. and Walter, P. (2005) Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease. Genome Biol. 6, R3.
-
(2005)
Genome Biol
, vol.6
-
-
Niwa, M.1
Patil, C.K.2
DeRisi, J.3
Walter, P.4
-
81
-
-
0033598996
-
A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response
-
Niwa, M., Sidrauski, C., Kaufman, R. J. and Walter, P. (1999) A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response. Cell 99, 691-702.
-
(1999)
Cell
, vol.99
, pp. 691-702
-
-
Niwa, M.1
Sidrauski, C.2
Kaufman, R.J.3
Walter, P.4
-
82
-
-
0035947778
-
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
-
Novoa, I., Zeng, H., Harding, H. P. and Ron, D. (2001) Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J. Cell Biol. 153, 1011-1022.
-
(2001)
J. Cell Biol
, vol.153
, pp. 1011-1022
-
-
Novoa, I.1
Zeng, H.2
Harding, H.P.3
Ron, D.4
-
83
-
-
31944450850
-
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
-
Oda, Y., Okada, T., Yoshida, H., Kaufman, R. J., Nagata, K. and Mori, K. (2006) Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J. Cell Biol. 172, 383-393.
-
(2006)
J. Cell Biol
, vol.172
, pp. 383-393
-
-
Oda, Y.1
Okada, T.2
Yoshida, H.3
Kaufman, R.J.4
Nagata, K.5
Mori, K.6
-
84
-
-
0000352663
-
Studies on the endoplasmic reticulum I. Its identification in cells in situ
-
Palade, G. E. and Porter, K. R. (1954) Studies on the endoplasmic reticulum. I. Its identification in cells in situ. J. Exp. Med. 100, 641-656.
-
(1954)
J. Exp. Med
, vol.100
, pp. 641-656
-
-
Palade, G.E.1
Porter, K.R.2
-
85
-
-
0038354461
-
Shutdown of translation: Lethal or protective? Unfolded protein response versus apoptosis
-
Paschen, W. (2003) Shutdown of translation: lethal or protective? Unfolded protein response versus apoptosis. J. Cereb. Blood Flow Metab. 23, 773-779.
-
(2003)
J. Cereb. Blood Flow Metab
, vol.23
, pp. 773-779
-
-
Paschen, W.1
-
86
-
-
14844321287
-
Synthetic modular systems-reverse engineering of signal transduction
-
Pawson, T. and Linding, R. (2005) Synthetic modular systems-reverse engineering of signal transduction. FEBS Lett. 579, 1808-1814.
-
(2005)
FEBS Lett
, vol.579
, pp. 1808-1814
-
-
Pawson, T.1
Linding, R.2
-
87
-
-
0026781849
-
Signalling across the endoplasmic reticulum membrane: Potential mechanisms
-
Price, B. D. (1992) Signalling across the endoplasmic reticulum membrane: potential mechanisms. Cell Signal 4, 465-470.
-
(1992)
Cell Signal
, vol.4
, pp. 465-470
-
-
Price, B.D.1
-
88
-
-
0022727584
-
Compartmentation of the rough endoplasmic reticulum
-
Pryme, I. F. (1986) Compartmentation of the rough endoplasmic reticulum. Mol. Cell. Biochem. 71, 3-18.
-
(1986)
Mol. Cell. Biochem
, vol.71
, pp. 3-18
-
-
Pryme, I.F.1
-
89
-
-
33745023062
-
Toward the systems biology of vesicle transport
-
Quenneville, N. R. and Conibear, E. (2006) Toward the systems biology of vesicle transport. Traffic 7, 761-768.
-
(2006)
Traffic
, vol.7
, pp. 761-768
-
-
Quenneville, N.R.1
Conibear, E.2
-
90
-
-
0347285295
-
A trip to the ER: Coping with stress
-
Rutkowski, D. T. and Kaufman, R. J. (2004) A trip to the ER: coping with stress. Trends Cell Biol. 14, 20-28.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 20-28
-
-
Rutkowski, D.T.1
Kaufman, R.J.2
-
91
-
-
0037219245
-
Lectin control of protein folding and sorting in the secretory pathway
-
Schrag, J. D., Procopio, D. O., Cygler, M., Thomas, D. Y. and Bergeron, J. J. (2003) Lectin control of protein folding and sorting in the secretory pathway. Trends Biochem. Sci. 28, 49-57.
-
(2003)
Trends Biochem. Sci
, vol.28
, pp. 49-57
-
-
Schrag, J.D.1
Procopio, D.O.2
Cygler, M.3
Thomas, D.Y.4
Bergeron, J.J.5
-
92
-
-
10444226462
-
ER stress and the unfolded protein response
-
Schroder, M. and Kaufman, R. J. (2005) ER stress and the unfolded protein response. Mutat. Res. 569, 29-63.
-
(2005)
Mutat. Res
, vol.569
, pp. 29-63
-
-
Schroder, M.1
Kaufman, R.J.2
-
93
-
-
26844489762
-
Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile
-
Schuldiner, M., Collins, S. R., Thompson, N. J., Denic, V., Bhamidipati, A., Punna, T., Ihmels, J., Andrews, B., Boone, C., Greenblatt, J. F., Weissman, J. S. and Krogan, N. J. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123, 507-519.
-
(2005)
Cell
, vol.123
, pp. 507-519
-
-
Schuldiner, M.1
Collins, S.R.2
Thompson, N.J.3
Denic, V.4
Bhamidipati, A.5
Punna, T.6
Ihmels, J.7
Andrews, B.8
Boone, C.9
Greenblatt, J.F.10
Weissman, J.S.11
Krogan, N.J.12
-
94
-
-
17044402604
-
The biological and chemical basis for tissue-selective amyloid disease
-
Sekijima, Y., Wiseman, R. L., Matteson, J., Hammarstrom, P., Miller, S. R., Sawkar, A. R., Balch, W. E. and Kelly, J. W. (2005) The biological and chemical basis for tissue-selective amyloid disease. Cell 121, 73-85.
-
(2005)
Cell
, vol.121
, pp. 73-85
-
-
Sekijima, Y.1
Wiseman, R.L.2
Matteson, J.3
Hammarstrom, P.4
Miller, S.R.5
Sawkar, A.R.6
Balch, W.E.7
Kelly, J.W.8
-
95
-
-
33646190885
-
The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases
-
Sekine, Y., Takeda, K. and Ichijo, H. (2006) The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases. Curr. Mol. Med. 6, 87-97.
-
(2006)
Curr. Mol. Med
, vol.6
, pp. 87-97
-
-
Sekine, Y.1
Takeda, K.2
Ichijo, H.3
-
96
-
-
33745606008
-
Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C elegans
-
Shen, X., Ellis, R. E., Sakaki, K. and Kaufman, R. J. (2005b). Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. PLoS Genet. 1, e37.
-
(2005)
PLoS Genet
, vol.1
-
-
Shen, X.1
Ellis, R.E.2
Sakaki, K.3
Kaufman, R.J.4
-
97
-
-
12844257546
-
Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response
-
Shen, J., Snapp, E. L., Lippincott-Schwartz, J. and Prywes, R. (2005a). Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response. Mol. Cell Biol. 25, 921-932.
-
(2005)
Mol. Cell Biol
, vol.25
, pp. 921-932
-
-
Shen, J.1
Snapp, E.L.2
Lippincott-Schwartz, J.3
Prywes, R.4
-
98
-
-
0031755020
-
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control
-
Shi, Y., Vattem, K. M., Sood, R., An, J., Liang, J., Stramm, L. and Wek, R. C. (1998) Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol. Cell Biol. 18, 7499-7509.
-
(1998)
Mol. Cell Biol
, vol.18
, pp. 7499-7509
-
-
Shi, Y.1
Vattem, K.M.2
Sood, R.3
An, J.4
Liang, J.5
Stramm, L.6
Wek, R.C.7
-
99
-
-
0030954870
-
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
-
Sidrauski, C. and Walter, P. (1997) The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 90, 1031-1039.
-
(1997)
Cell
, vol.90
, pp. 1031-1039
-
-
Sidrauski, C.1
Walter, P.2
-
100
-
-
0346096508
-
Quality control in the endoplasmic reticulum protein factory
-
Sitia, R. and Braakman, I. (2003) Quality control in the endoplasmic reticulum protein factory. Nature 426, 891-894.
-
(2003)
Nature
, vol.426
, pp. 891-894
-
-
Sitia, R.1
Braakman, I.2
-
101
-
-
0036063247
-
BiP binding keeps ATF6 at bay
-
Sommer, T. and Jarosch, E. (2002) BiP binding keeps ATF6 at bay. Dev. Cell 3, 1-2.
-
(2002)
Dev. Cell
, vol.3
, pp. 1-2
-
-
Sommer, T.1
Jarosch, E.2
-
102
-
-
0742322956
-
The ER protein folding sensor UDPglucose glycoprotein-glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation
-
Taylor, S. C., Ferguson, A. D., Bergeron, J. J. and Thomas, D. Y. (2004) The ER protein folding sensor UDPglucose glycoprotein-glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation. Nat. Struct. Mol. Biol. 11, 128-134.
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 128-134
-
-
Taylor, S.C.1
Ferguson, A.D.2
Bergeron, J.J.3
Thomas, D.Y.4
-
103
-
-
0038779355
-
Glycopeptide specificity of the secretory protein folding sensor UDP-glucose glycoprotein: Glucosyltransferase
-
Taylor, S. C., Thibault, P., Tessier, D. C., Bergeron, J. J. and Thomas, D. Y. (2003) Glycopeptide specificity of the secretory protein folding sensor UDP-glucose glycoprotein: glucosyltransferase. EMBO Rep. 4, 405-411.
-
(2003)
EMBO Rep
, vol.4
, pp. 405-411
-
-
Taylor, S.C.1
Thibault, P.2
Tessier, D.C.3
Bergeron, J.J.4
Thomas, D.Y.5
-
104
-
-
0032493662
-
p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element A potential role for the transcription factor ATF6
-
Thuerauf, D. J., Arnold, N. D., Zechner, D., Hanford, D. S., DeMartin, K. M., McDonough, P. M., Prywes, R. and Glembotski, C. C. (1998) p38 Mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6. J. Biol. Chem. 273, 20636-20643.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 20636-20643
-
-
Thuerauf, D.J.1
Arnold, N.D.2
Zechner, D.3
Hanford, D.S.4
DeMartin, K.M.5
McDonough, P.M.6
Prywes, R.7
Glembotski, C.C.8
-
105
-
-
2442647920
-
Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum stress response gene induction
-
Thuerauf, D. J., Morrison, L. and Glembotski, C. C. (2004) Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum stress response gene induction. J. Biol. Chem. 279, 21078-21084.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 21078-21084
-
-
Thuerauf, D.J.1
Morrison, L.2
Glembotski, C.C.3
-
106
-
-
0031733824
-
Lectins as chaperones in glycoprotein folding
-
Trombetta, E. S. and Helenius, A. (1998) Lectins as chaperones in glycoprotein folding. Curr. Opin. Struct. Biol. 8, 587-592.
-
(1998)
Curr. Opin. Struct. Biol
, vol.8
, pp. 587-592
-
-
Trombetta, E.S.1
Helenius, A.2
-
107
-
-
0344393021
-
Quality control and protein folding in the secretory pathway
-
Trombetta, E. S. and Parodi, A. J. (2003) Quality control and protein folding in the secretory pathway. Annu. Rev. Cell Dev. Biol. 19, 649-676.
-
(2003)
Annu. Rev. Cell Dev. Biol
, vol.19
, pp. 649-676
-
-
Trombetta, E.S.1
Parodi, A.J.2
-
108
-
-
0033693855
-
IRE1 and efferent signaling from the endoplasmic reticulum
-
Urano, F., Bertolotti, A. and Ron, D. (2000a). IRE1 and efferent signaling from the endoplasmic reticulum. J. Cell. Sci. 113, 3697-3702.
-
(2000)
J. Cell. Sci
, vol.113
, pp. 3697-3702
-
-
Urano, F.1
Bertolotti, A.2
Ron, D.3
-
109
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano, F., Wang, X., Bertolotti, A., Zhang, Y., Chung, P., Harding, H. P. and Ron, D. (2000b). Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287, 664-666.
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
Zhang, Y.4
Chung, P.5
Harding, H.P.6
Ron, D.7
-
110
-
-
11244353370
-
The ire1 and ptc2 genes involved in the unfolded protein response pathway in the filamentous fungus Trichoderma reesei
-
Valkonen, M., Penttila, M. and Saloheimo, M. (2004) The ire1 and ptc2 genes involved in the unfolded protein response pathway in the filamentous fungus Trichoderma reesei. Mol Genet Genomics 272, 443-451.
-
(2004)
Mol Genet Genomics
, vol.272
, pp. 443-451
-
-
Valkonen, M.1
Penttila, M.2
Saloheimo, M.3
-
111
-
-
16544394131
-
Protein quality control mechanisms and protein storage in the endoplasmic reticulum
-
Vitale, A. and Ceriotti, A. (2004) Protein quality control mechanisms and protein storage in the endoplasmic reticulum. A conflict of interests? Plant Physiol. 136, 3420-3426.
-
(2004)
A conflict of interests? Plant Physiol
, vol.136
, pp. 3420-3426
-
-
Vitale, A.1
Ceriotti, A.2
-
113
-
-
0029938805
-
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase
-
Wang, X. Z. and Ron, D. (1996) Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase. Science 272, 1347-1349.
-
(1996)
Science
, vol.272
, pp. 1347-1349
-
-
Wang, X.Z.1
Ron, D.2
-
114
-
-
0034282912
-
Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response
-
Wang, Y., Shen, J., Arenzana, N., Tirasophon, W., Kaufman, R. J. and Prywes, R. (2000) Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. J. Biol. Chem. 275, 27013-27020.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 27013-27020
-
-
Wang, Y.1
Shen, J.2
Arenzana, N.3
Tirasophon, W.4
Kaufman, R.J.5
Prywes, R.6
-
115
-
-
0031948846
-
Protein serine/threonine phosphatase Ptc2p negatively regulates the unfolded-protein response by dephosphorylating Ire1p kinase
-
Welihinda, A. A., Tirasophon, W., Green, S. R. and Kaufman, R. J. (1998) Protein serine/threonine phosphatase Ptc2p negatively regulates the unfolded-protein response by dephosphorylating Ire1p kinase. Mol. Cell Biol. 18, 1967-1977.
-
(1998)
Mol. Cell Biol
, vol.18
, pp. 1967-1977
-
-
Welihinda, A.A.1
Tirasophon, W.2
Green, S.R.3
Kaufman, R.J.4
-
116
-
-
33645156429
-
From acute ER stress to physiological roles of the Unfolded Protein Response
-
Wu, J. and Kaufman, R. J. (2006) From acute ER stress to physiological roles of the Unfolded Protein Response. Cell Death Differ. 13, 374-384.
-
(2006)
Cell Death Differ
, vol.13
, pp. 374-384
-
-
Wu, J.1
Kaufman, R.J.2
-
117
-
-
33646061642
-
Quality control system of the endoplasmic reticulum and related diseases
-
Wu, J. C., Liang, Z. Q. and Qin, Z. H. (2006) Quality control system of the endoplasmic reticulum and related diseases. Acta Biochim. Biophys. Sin. (Shanghai) 38, 219-226.
-
(2006)
Acta Biochim. Biophys. Sin. (Shanghai)
, vol.38
, pp. 219-226
-
-
Wu, J.C.1
Liang, Z.Q.2
Qin, Z.H.3
-
118
-
-
26444442450
-
Endoplasmic reticulum stress: Cell life and death decisions
-
Xu, C., Bailly-Maitre, B. and Reed, J. C. (2005) Endoplasmic reticulum stress: cell life and death decisions. J. Clin. Invest. 115, 2656-2664.
-
(2005)
J. Clin. Invest
, vol.115
, pp. 2656-2664
-
-
Xu, C.1
Bailly-Maitre, B.2
Reed, J.C.3
-
119
-
-
0036386967
-
FAD-linked presenilin-1 mutants impede translation regulation under ER stress
-
Yasuda, Y., Kudo, T., Katayama, T., Imaizumi, K., Yatera, M., Okochi, M., Yamamori, H., Matsumoto, N., Kida, T., Fukumori, A., Okumura, M., Tohyama, M. and Takeda, M. (2002) FAD-linked presenilin-1 mutants impede translation regulation under ER stress. Biochem. Biophys. Res. Commun. 296, 313-318.
-
(2002)
Biochem. Biophys. Res. Commun
, vol.296
, pp. 313-318
-
-
Yasuda, Y.1
Kudo, T.2
Katayama, T.3
Imaizumi, K.4
Yatera, M.5
Okochi, M.6
Yamamori, H.7
Matsumoto, N.8
Kida, T.9
Fukumori, A.10
Okumura, M.11
Tohyama, M.12
Takeda, M.13
-
120
-
-
0034515724
-
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
-
Ye, J., Rawson, R. B., Komuro, R., Chen, X., Dave, U. P., Prywes, R., Brown, M. S. and Goldstein, J. L. (2000) ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol. Cell 6, 1355-1364.
-
(2000)
Mol. Cell
, vol.6
, pp. 1355-1364
-
-
Ye, J.1
Rawson, R.B.2
Komuro, R.3
Chen, X.4
Dave, U.P.5
Prywes, R.6
Brown, M.S.7
Goldstein, J.L.8
-
121
-
-
3042677637
-
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
-
Ye, Y., Shibata, Y., Yun, C., Ron, D. and Rapoport, T. A. (2004) A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature 429, 841-847.
-
(2004)
Nature
, vol.429
, pp. 841-847
-
-
Ye, Y.1
Shibata, Y.2
Yun, C.3
Ron, D.4
Rapoport, T.A.5
-
122
-
-
0141814712
-
A novel role for N-glycans in the ERAD system
-
Yoshida, Y. (2003) A novel role for N-glycans in the ERAD system. J. Biochem. (Tokyo) 134, 183-190.
-
(2003)
J. Biochem. (Tokyo)
, vol.134
, pp. 183-190
-
-
Yoshida, Y.1
-
123
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida, H., Matsui, T., Yamamoto, A., Okada, T. and Mori, K. (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107, 881-891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
124
-
-
1842509855
-
ATF6 modulates SREBP2-mediated lipogenesis
-
Zeng, L., Lu, M., Mori, K., Luo, S., Lee, A. S., Zhu, Y. and Shyy, J. Y. (2004) ATF6 modulates SREBP2-mediated lipogenesis. EMBO J. 23, 950-958.
-
(2004)
EMBO J
, vol.23
, pp. 950-958
-
-
Zeng, L.1
Lu, M.2
Mori, K.3
Luo, S.4
Lee, A.S.5
Zhu, Y.6
Shyy, J.Y.7
-
125
-
-
33645996396
-
Protein folding in the endoplasmic reticulum and the unfolded protein response
-
Zhang, K. and Kaufman, R. J. (2006a). Protein folding in the endoplasmic reticulum and the unfolded protein response. Handb. Exp. Pharmacol. 172, 69-91.
-
(2006)
Handb. Exp. Pharmacol
, vol.172
, pp. 69-91
-
-
Zhang, K.1
Kaufman, R.J.2
-
126
-
-
33644858343
-
The unfolded protein response: A stress signaling pathway critical for health and disease
-
Zhang, K. and Kaufman, R. J. (2006b). The unfolded protein response: a stress signaling pathway critical for health and disease. Neurology 66, S102-S109.
-
(2006)
Neurology
, vol.66
, pp. S102-S109
-
-
Zhang, K.1
Kaufman, R.J.2
-
127
-
-
0030850013
-
Interaction of ATF6 and serum response factor
-
Zhu, C., Johansen, F. E. and Prywes, R. (1997) Interaction of ATF6 and serum response factor. Mol. Cell Biol. 17, 4957-4966.
-
(1997)
Mol. Cell Biol
, vol.17
, pp. 4957-4966
-
-
Zhu, C.1
Johansen, F.E.2
Prywes, R.3
|