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Volumn 35, Issue 1, 2002, Pages 61-66

Modulation of life and death by the tumor necrosis factor receptor-associated factors (TRAFs)

Author keywords

Apoptosis; Cell survival; TNF receptor superfamily; TRAF

Indexed keywords

ADAPTOR PROTEIN; CELL SURFACE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; TNF RECEPTOR-ASSOCIATED FACTOR 4; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 4; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 5; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR PROTEIN 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR PROTEIN 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR PROTEIN 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR PROTEIN 5; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR PROTEIN 6; UNCLASSIFIED DRUG;

EID: 0037203547     PISSN: 12258687     EISSN: None     Source Type: Journal    
DOI: 10.5483/bmbrep.2002.35.1.061     Document Type: Review
Times cited : (73)

References (45)
  • 1
    • 0032530455 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated factors (TRAFs) a family of adapter proteins that regulates life and death
    • Arch, R. H., Gedrich, R. W. and Thompson, C. B. (1998) Tumor necrosis factor receptor-associated factors (TRAFs) a family of adapter proteins that regulates life and death. Genes & Dev. 12, 2821-2830.
    • (1998) Genes & Dev. , vol.12 , pp. 2821-2830
    • Arch, R.H.1    Gedrich, R.W.2    Thompson, C.B.3
  • 2
    • 0030033193 scopus 로고    scopus 로고
    • Transducers of life and death: TNF receptor superfamily and associated proteins
    • Baker, S. J. and Reddy, E. P. (1996) Transducers of life and death: TNF receptor superfamily and associated proteins. Oncogene 12, 1-9.
    • (1996) Oncogene , vol.12 , pp. 1-9
    • Baker, S.J.1    Reddy, E.P.2
  • 3
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • Baldwin, A. S. J. (1996) The NF-κB and IκB proteins: New discoveries and insights. Ann. Rev. Immunol. 14, 649-681.
    • (1996) Ann. Rev. Immunol. , vol.14 , pp. 649-681
    • Baldwin, A.S.J.1
  • 4
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-κB in preventing TNF-α-induced cell death
    • Beg, A.A. and Baltimore D. (1996) An essential role for NF-κB in preventing TNF-α-induced cell death. Science 274, 782-784.
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 5
    • 0029761275 scopus 로고    scopus 로고
    • TRAF6 is a signal transducers for interleukin-1
    • Cao, Z., Xiong, J., Takeuchi, M., Kurama, T. and Goeddel, D. V. (1996) TRAF6 is a signal transducers for interleukin-1. Nature 383, 443-446.
    • (1996) Nature , vol.383 , pp. 443-446
    • Cao, Z.1    Xiong, J.2    Takeuchi, M.3    Kurama, T.4    Goeddel, D.V.5
  • 6
    • 0029917841 scopus 로고    scopus 로고
    • TANK, a co-inducer with TRAF2 of TNF- and CD40L-mediated NF-activation
    • Cheng, G. and Baltimore, D. (1996) TANK, a co-inducer with TRAF2 of TNF- and CD40L-mediated NF-activation. Genes & Dev. 10, 963-973.
    • (1996) Genes & Dev. , vol.10 , pp. 963-973
    • Cheng, G.1    Baltimore, D.2
  • 7
    • 0030661665 scopus 로고    scopus 로고
    • Dominant negative mutants of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-β receptor
    • Force, W. R., Cheung, T. C. and Ware, C. F. (1997) Dominant negative mutants of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-β receptor. J. Biol. Chem. 272, 30835-30840.
    • (1997) J. Biol. Chem. , vol.272 , pp. 30835-30840
    • Force, W.R.1    Cheung, T.C.2    Ware, C.F.3
  • 8
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
    • Hsu, H., Xiong, J. and Goeddel, D. V. (1995) The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 81, 495-504.
    • (1995) Cell , vol.81 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 9
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • Hsu, H., Shu, H. B., Pan, M. G. and Goeddel, D. V. (1996) TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84, 299-308.
    • (1996) Cell , vol.84 , pp. 299-308
    • Hsu, H.1    Shu, H.B.2    Pan, M.G.3    Goeddel, D.V.4
  • 11
    • 0034803045 scopus 로고    scopus 로고
    • Caspase-cleaved TRAF1 negatively regulates the antiapoptotic signals of TRAF2 during TNF-induced cell death
    • Jang, H. D., Chung, Y. M., Baik, J. Y., Choi, Y. G., Park, I. S., Jung, Y. K. and Lee, S. Y. (2001) Caspase-cleaved TRAF1 negatively regulates the antiapoptotic signals of TRAF2 during TNF-induced cell death. Biochem. Biophy. Res. Commun. 281, 499-505.
    • (2001) Biochem. Biophy. Res. Commun. , vol.281 , pp. 499-505
    • Jang, H.D.1    Chung, Y.M.2    Baik, J.Y.3    Choi, Y.G.4    Park, I.S.5    Jung, Y.K.6    Lee, S.Y.7
  • 12
    • 0032774411 scopus 로고    scopus 로고
    • Signaling by tumor necrosis factor receptors: Pathways, paradigms and targets for therapeutic modulation
    • Kaufman, D. and Choi, Y. (1999) Signaling by tumor necrosis factor receptors: pathways, paradigms and targets for therapeutic modulation. Intern. Rev. Immunol. 18, 405-427.
    • (1999) Intern. Rev. Immunol. , vol.18 , pp. 405-427
    • Kaufman, D.1    Choi, Y.2
  • 13
    • 0032033132 scopus 로고    scopus 로고
    • The death domain kinase RIP mediates the TNF-induced NF-κB signal
    • Kelliher, M. A., Grimm, S., Ishida, Y., Kuo, F., Stanger, B. Z. and Leder, p. (1998) The death domain kinase RIP mediates the TNF-induced NF-κB signal. Immunity 8, 297-303.
    • (1998) Immunity , vol.8 , pp. 297-303
    • Kelliher, M.A.1    Grimm, S.2    Ishida, Y.3    Kuo, F.4    Stanger, B.Z.5    Leder, P.6
  • 14
    • 0035618703 scopus 로고    scopus 로고
    • From cytosol to mitochondria: The Bax translocation story
    • Khaled, A. R. and Durum, S. K. (2001) From cytosol to mitochondria: the Bax translocation story. J. Biochem. Mol. Biol. 34, 391-394.
    • (2001) J. Biochem. Mol. Biol. , vol.34 , pp. 391-394
    • Khaled, A.R.1    Durum, S.K.2
  • 15
    • 0035627959 scopus 로고    scopus 로고
    • Osteoclast differentiation factor engages the PI3-kinase, p38 and ERK pathways for avian osteoclast differentiation
    • Kim, H. H., Kim, H. M., Kwack, K., Kim, S. W. and Lee, Z. H. (2001) Osteoclast differentiation factor engages the PI3-kinase, p38 and ERK pathways for avian osteoclast differentiation. J. Biochem. Mol. Biol. 34, 421-427.
    • (2001) J. Biochem. Mol. Biol. , vol.34 , pp. 421-427
    • Kim, H.H.1    Kim, H.M.2    Kwack, K.3    Kim, S.W.4    Lee, Z.H.5
  • 16
    • 0040084598 scopus 로고    scopus 로고
    • CD30/TNF receptor-associated factor interaction: NF-κB activation and binding specificity
    • Lee, S. Y., Lee, S. Y., Kandala, G., Liou, M., Liou, H. and Choi, Y. (1996a) CD30/TNF receptor-associated factor interaction: NF-κB activation and binding specificity. Proc. Natl. Acad. Sci. USA 93, 9699-9703.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9699-9703
    • Lee, S.Y.1    Lee, S.Y.2    Kandala, G.3    Liou, M.4    Liou, H.5    Choi, Y.6
  • 17
    • 0347667234 scopus 로고    scopus 로고
    • TRAF-interacting protein (TRIP): A novel component of the TNFR-and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kB activation
    • Lee, S. Y., Lee, S. Y. and Choi, Y. (1997a) TRAF-interacting protein (TRIP): A novel component of the TNFR-and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kB activation. J. Exp. Med. 185, 1275-1285.
    • (1997) J. Exp. Med. , vol.185 , pp. 1275-1285
    • Lee, S.Y.1    Lee, S.Y.2    Choi, Y.3
  • 18
    • 0008206988 scopus 로고    scopus 로고
    • TRAF2 is essential for JNK but not NF-kB activation and regulates lymphocyte proliferation and survival
    • Lee, S. Y., Reichlin, A., Santana, A., Sokol, K. A., Nussenzweig, M., and Choi Y. (1997b) TRAF2 is essential for JNK but not NF-kB activation and regulates lymphocyte proliferation and survival. Immunity 7, 703-713.
    • (1997) Immunity , vol.7 , pp. 703-713
    • Lee, S.Y.1    Reichlin, A.2    Santana, A.3    Sokol, K.A.4    Nussenzweig, M.5    Choi, Y.6
  • 19
    • 0005231498 scopus 로고    scopus 로고
    • Stimulus-dependent synergism of the antiapoptotic tumor necrosis factor receptor-β associating factor 2 (TRAF2) and nuclear factor kappa B pathways
    • Lee, S. Y., Kaufman, D. R., Mora, A. L., Santana, A., Boothby, M. and Choi, Y. (1998) Stimulus-dependent synergism of the antiapoptotic tumor necrosis factor receptor-β associating factor 2 (TRAF2) and nuclear factor kappa B pathways. J. Exp. Med. 188, 1381-1384.
    • (1998) J. Exp. Med. , vol.188 , pp. 1381-1384
    • Lee, S.Y.1    Kaufman, D.R.2    Mora, A.L.3    Santana, A.4    Boothby, M.5    Choi, Y.6
  • 20
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley, R. M., Killeen, N. and Lenardo, M. J. (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104, 487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 22
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
    • Malinin, N. L., Boldin, M. P., Kovalenko, A. V. and Wallach, D. (1997) MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 385, 540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 24
    • 15844428836 scopus 로고    scopus 로고
    • TRAF5, an activator of NF-κB and putative signal transducer for the lymphotoxin-β receptor
    • Nakano, H., Oshima, H., Chung, W., Williams-Abbott, L., Ware, C. F., Yagita, H. and Okumura, K. (1996) TRAF5, an activator of NF-κB and putative signal transducer for the lymphotoxin-β receptor. J. Biol. Chem. 271, 14661-14664.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14661-14664
    • Nakano, H.1    Oshima, H.2    Chung, W.3    Williams-Abbott, L.4    Ware, C.F.5    Yagita, H.6    Okumura, K.7
  • 25
    • 0001033803 scopus 로고    scopus 로고
    • Structural basis for self-association and receptor recognition of human TRAF2
    • Park, Y. C., Burkitt, V., Villa, A. R., Tong, L. and Wu, H. (1999) Structural basis for self-association and receptor recognition of human TRAF2. Nature 398, 533-538
    • (1999) Nature , vol.398 , pp. 533-538
    • Park, Y.C.1    Burkitt, V.2    Villa, A.R.3    Tong, L.4    Wu, H.5
  • 26
    • 0031048067 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induced activation of c-jun N-terminal kinase is mediated by TRAF2
    • Reinhard, C., Shamoon, B., Shyamala, V. and Williams, L. T. (1997) Tumor necrosis factor-α induced activation of c-jun N-terminal kinase is mediated by TRAF2. EMBO J. 16, 1080-1092.
    • (1997) EMBO J. , vol.16 , pp. 1080-1092
    • Reinhard, C.1    Shamoon, B.2    Shyamala, V.3    Williams, L.T.4
  • 27
    • 0028124428 scopus 로고
    • A novel family of putative signal transducers associated with the cytoplasmic domain of the 75kDa tumor necrosis factor receptor
    • Rothe, M., Wong, S. C., Henzel, W. J. and Goeddel, D. V. (1994) A novel family of putative signal transducers associated with the cytoplasmic domain of the 75kDa tumor necrosis factor receptor. Cell 78, 681-692.
    • (1994) Cell , vol.78 , pp. 681-692
    • Rothe, M.1    Wong, S.C.2    Henzel, W.J.3    Goeddel, D.V.4
  • 28
    • 0029595282 scopus 로고
    • The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins
    • Rothe, M., Pan, M. G., Henzel, W. J., Ayres, T. M. and Goeddel, D. V. (1995) The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83, 1243-1252.
    • (1995) Cell , vol.83 , pp. 1243-1252
    • Rothe, M.1    Pan, M.G.2    Henzel, W.J.3    Ayres, T.M.4    Goeddel, D.V.5
  • 29
  • 32
    • 12644272789 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) mediated kinsae cascades: Bifurcation of nuclear factor-B and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2
    • Song, H. Y., Regnier, C. H., Kirschning, C. J., Goeddel, D. V. and Rothe, M. (1997) Tumor necrosis factor (TNF) mediated kinsae cascades: Bifurcation of nuclear factor-B and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2. Proc. Natl. Acad. Sci. USA 94, 9792-9796.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9792-9796
    • Song, H.Y.1    Regnier, C.H.2    Kirschning, C.J.3    Goeddel, D.V.4    Rothe, M.5
  • 34
    • 0033636538 scopus 로고    scopus 로고
    • Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway
    • Tsao, D. H. H., McDonagh, T., Telliez J. B., Hsu, S., Malakian, K., Xu, G. Y. and Lin, L. L. (2000) Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway. Mol. Cell 5, 1051-1057.
    • (2000) Mol. Cell , vol.5 , pp. 1051-1057
    • Tsao, D.H.H.1    McDonagh, T.2    Telliez, J.B.3    Hsu, S.4    Malakian, K.5    Xu, G.Y.6    Lin, L.L.7
  • 35
    • 0034752285 scopus 로고    scopus 로고
    • TRAF1 is a negative regulator of TNF signaling: Enhanced TNF signaling in TRAF1-deficient mice
    • Tsitsikov, E. N., Laouin, D., Dunn, I. F., Sannikova, T. Y., Davidson, L., Alt, F. W. and Geha, R. S. (2001) TRAF1 is a negative regulator of TNF signaling: enhanced TNF signaling in TRAF1-deficient mice. Immunity 15, 647-657.
    • (2001) Immunity , vol.15 , pp. 647-657
    • Tsitsikov, E.N.1    Laouin, D.2    Dunn, I.F.3    Sannikova, T.Y.4    Davidson, L.5    Alt, F.W.6    Geha, R.S.7
  • 38
    • 0034982801 scopus 로고    scopus 로고
    • The TNF-receptor-associated factor family Scaffold molecules for cytokine receptors, kinases and their regulators
    • Wajant, H., Henkler, F. and Scheurich, P. (2001) The TNF-receptor-associated factor family Scaffold molecules for cytokine receptors, kinases and their regulators. Cellular Signaling 13, 389-400.
    • (2001) Cellular Signaling , vol.13 , pp. 389-400
    • Wajant, H.1    Henkler, F.2    Scheurich, P.3
  • 40
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-B
    • Wang, C. Y., Mayo, M. W. and Baldwin, A. S. (1996) TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-B. Science 274, 784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin, A.S.3
  • 41
    • 0032561198 scopus 로고    scopus 로고
    • The TRAF family of signal transducers mediates NF-kB activation by the TRANCE receptor
    • Wong, B. R., Josien, R., Lee, S. Y. Vologodskaia, M., Steinman, R. M. and Choi, Y. (1998) The TRAF family of signal transducers mediates NF-kB activation by the TRANCE receptor. J. Biol. Chem. 273, 28355-28359.
    • (1998) J. Biol. Chem. , vol.273 , pp. 28355-28359
    • Wong, B.R.1    Josien, R.2    Lee, S.Y.3    Vologodskaia, M.4    Steinman, R.M.5    Choi, Y.6
  • 42
    • 0033393957 scopus 로고    scopus 로고
    • TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src
    • Wong, B. R., Besser, D., Kim, N., Arron, J. R., Vologodskaia, M., Hanafusa, H. and Choi, Y. (1999) TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src. Mol. Cell 4, 1041-1049.
    • (1999) Mol. Cell , vol.4 , pp. 1041-1049
    • Wong, B.R.1    Besser, D.2    Kim, N.3    Arron, J.R.4    Vologodskaia, M.5    Hanafusa, H.6    Choi, Y.7
  • 43
    • 0030292777 scopus 로고    scopus 로고
    • Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses
    • Xu, Y., Cheng, G. and Baltimore, D. (1996) Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. Immunity 5, 407-415.
    • (1996) Immunity , vol.5 , pp. 407-415
    • Xu, Y.1    Cheng, G.2    Baltimore, D.3
  • 44
    • 0033197872 scopus 로고    scopus 로고
    • The structural basis for the recognition of diverse receptor sequences by TRAF2
    • Ye, H., Park, Y. C., Kreishman, M., Kieff, E. and Wu, H. (1999) The structural basis for the recognition of diverse receptor sequences by TRAF2. Mol. Cell 4, 321-330.
    • (1999) Mol. Cell , vol.4 , pp. 321-330
    • Ye, H.1    Park, Y.C.2    Kreishman, M.3    Kieff, E.4    Wu, H.5


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