메뉴 건너뛰기




Volumn 3, Issue 4-5, 2007, Pages 171-181

Mammary stem and progenitor cell regulation

Author keywords

Estrogen receptor ; Mammary tumorigenesis; Musashi1; Peroxisome proliferator activated receptor (PPAR ); Stem cell antigen 1 (Sca 1)

Indexed keywords

ANTIESTROGEN; BETA CATENIN; BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; CD24 ANTIGEN; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYTOKERATIN 14; CYTOKERATIN 18; ESTROGEN RECEPTOR; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; HERMES ANTIGEN; IMATINIB; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NOTCH RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROGESTERONE RECEPTOR; PROTEIN KINASE B; RAS PROTEIN; RETINOID X RECEPTOR; STAT PROTEIN; STEM CELL ANTIGEN 1; T CELL FACTOR PROTEIN; UNINDEXED DRUG; WNT PROTEIN;

EID: 38449099002     PISSN: 15740153     EISSN: None     Source Type: Journal    
DOI: 10.3233/CBM-2007-34-502     Document Type: Review
Times cited : (9)

References (132)
  • 1
    • 29744436903 scopus 로고    scopus 로고
    • Human breast epithelial stem cells and their regulation
    • H. Kalirai and R.B. Clarke, Human breast epithelial stem cells and their regulation, J Pathol 208 (2006), 7-16.
    • (2006) J Pathol , vol.208 , pp. 7-16
    • Kalirai, H.1    Clarke, R.B.2
  • 3
    • 33646045010 scopus 로고    scopus 로고
    • Stem cells and cancer: Two faces of Eve
    • M.F. Clarke and M. Fuller, Stem cells and cancer: Two faces of Eve, Cell 124 (2006), 1111-1115.
    • (2006) Cell , vol.124 , pp. 1111-1115
    • Clarke, M.F.1    Fuller, M.2
  • 4
    • 4644342477 scopus 로고    scopus 로고
    • Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice
    • M.D. Henry, A.A. Triplett, K.B. Oh, G.H. Smith and K.U. Wagner, Parity-induced mammary epithelial cells facilitate tumorigenesis in MMTV-neu transgenic mice, Oncogene 23 (2004), 6980-6985.
    • (2004) Oncogene , vol.23 , pp. 6980-6985
    • Henry, M.D.1    Triplett, A.A.2    Oh, K.B.3    Smith, G.H.4    Wagner, K.U.5
  • 5
    • 0030743240 scopus 로고    scopus 로고
    • Intrinsic and extrinsic control of hemopoietic stem cell numbers: Mapping of a stem cell gene
    • G. de Haan and G. Van Zant, Intrinsic and extrinsic control of hemopoietic stem cell numbers: Mapping of a stem cell gene, J Exp Med 186 (1997), 529-536.
    • (1997) J Exp Med , vol.186 , pp. 529-536
    • de Haan, G.1    Van Zant, G.2
  • 6
    • 9144220757 scopus 로고    scopus 로고
    • Terminal endbuds and acini as the respective major targets for chemical and sporadic carcinogenesis in the mammary glands of human c-Ha-ras protooncogene rats
    • T. Hamaguchi, Y. Matsuoka, H. Kawaguchi et al., Terminal endbuds and acini as the respective major targets for chemical and sporadic carcinogenesis in the mammary glands of human c-Ha-ras protooncogene rats, Breast Cancer Res Treat 83 (2004), 43-56.
    • (2004) Breast Cancer Res Treat , vol.83 , pp. 43-56
    • Hamaguchi, T.1    Matsuoka, Y.2    Kawaguchi, H.3
  • 7
    • 0035985487 scopus 로고    scopus 로고
    • Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis
    • L. Sivaraman, J. Gay, S.G. Hilsenbeck et al., Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis, Breast Cancer Res Treat 73 (2002), 75-93.
    • (2002) Breast Cancer Res Treat , vol.73 , pp. 75-93
    • Sivaraman, L.1    Gay, J.2    Hilsenbeck, S.G.3
  • 8
    • 0348134978 scopus 로고    scopus 로고
    • Evidence of progenitor cells of glandular and myoepithelial cell lineages in the human adult female breast epithelium: A new progenitor (adult stem) cell concept
    • W. Boecker and H. Buerger, Evidence of progenitor cells of glandular and myoepithelial cell lineages in the human adult female breast epithelium: a new progenitor (adult stem) cell concept, Cell Prolif 36 Suppl 1) (2003), 73-44.
    • (2003) Cell Prolif , vol.36 , Issue.SUPPL. 1 , pp. 73-44
    • Boecker, W.1    Buerger, H.2
  • 10
    • 0031003599 scopus 로고    scopus 로고
    • Three division-competent, structurally-distinct cell populations contribute to murine mammary epithelial renewal
    • G. Chepko and G.H. Smith, Three division-competent, structurally-distinct cell populations contribute to murine mammary epithelial renewal, Tissue Cell 29 (1997), 239-253.
    • (1997) Tissue Cell , vol.29 , pp. 239-253
    • Chepko, G.1    Smith, G.H.2
  • 11
    • 0034724165 scopus 로고    scopus 로고
    • G. Shyamala, X. Yang, R.D. Cardiff and E. Dale, Impact of progesierone receptor on cell-fate decisions during mammary gland development, Proc Natl Acad Sci USA 97 (2000), 3044-3049.
    • G. Shyamala, X. Yang, R.D. Cardiff and E. Dale, Impact of progesierone receptor on cell-fate decisions during mammary gland development, Proc Natl Acad Sci USA 97 (2000), 3044-3049.
  • 12
    • 0033199889 scopus 로고    scopus 로고
    • Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function
    • J.P. Lydon, G. Ge, F.S. Kittrell, D. Medina and B.W. O'Malley, Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function, Cancer Res 59 (1999), 4276-4284.
    • (1999) Cancer Res , vol.59 , pp. 4276-4284
    • Lydon, J.P.1    Ge, G.2    Kittrell, F.S.3    Medina, D.4    O'Malley, B.W.5
  • 13
    • 24044433540 scopus 로고    scopus 로고
    • Characterization of medroxyprogesterone and DMBA-induced multilineage mammary rumors by gene expression profiling
    • Y. Yin, R. Bai, R.G. Russell et al., Characterization of medroxyprogesterone and DMBA-induced multilineage mammary rumors by gene expression profiling, Mol Carcinog 44 (2005), 42-50.
    • (2005) Mol Carcinog , vol.44 , pp. 42-50
    • Yin, Y.1    Bai, R.2    Russell, R.G.3
  • 14
    • 0038460529 scopus 로고    scopus 로고
    • Human mammary luminal epithelial cells contain progenitors to myoepithelial cells
    • C. Pechoux, T. Gudjonsson, L. Ronnov-Jessen, M.J. Bissell and O.W. Petersen, Human mammary luminal epithelial cells contain progenitors to myoepithelial cells, Dev Biol 206 (1999), 88-99.
    • (1999) Dev Biol , vol.206 , pp. 88-99
    • Pechoux, C.1    Gudjonsson, T.2    Ronnov-Jessen, L.3    Bissell, M.J.4    Petersen, O.W.5
  • 16
    • 84965810273 scopus 로고
    • Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice
    • K.B. DeOme, L.J. Faulkin, H.A. Bern and P.B. Blair, Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice, Cancer Res 19 (1959), 515-520.
    • (1959) Cancer Res , vol.19 , pp. 515-520
    • DeOme, K.B.1    Faulkin, L.J.2    Bern, H.A.3    Blair, P.B.4
  • 18
    • 0021153316 scopus 로고
    • Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro
    • K.G. Danielson, C.J. Oborn, E.M. Durban, J.S. Butel and D. Medina, Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro, Proc Natl Acad Sci USA 81 (1984), 3756-3760.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 3756-3760
    • Danielson, K.G.1    Oborn, C.J.2    Durban, E.M.3    Butel, J.S.4    Medina, D.5
  • 19
    • 33646172539 scopus 로고    scopus 로고
    • Isolation of mouse mammary epithelial progenitor cells with basal characteristics from the Comma-Dbeta cell line
    • M.A. Deugnier, M.M. Faraldo, J. Teuliere, J.P. Thiery, D. Medina and M.A. Glukhova, Isolation of mouse mammary epithelial progenitor cells with basal characteristics from the Comma-Dbeta cell line, Dev Biol (2006).
    • (2006) Dev Biol
    • Deugnier, M.A.1    Faraldo, M.M.2    Teuliere, J.3    Thiery, J.P.4    Medina, D.5    Glukhova, M.A.6
  • 20
    • 0023889974 scopus 로고
    • A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland
    • G.H. Smith and D. Medina, A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland, J Cell Sci 90 Pt 1) (1988), 173-183.
    • (1988) J Cell Sci , vol.90 , Issue.PART 1 , pp. 173-183
    • Smith, G.H.1    Medina, D.2
  • 21
    • 0029868224 scopus 로고    scopus 로고
    • Experimental mammary epithelial morphogenesis in an in vivo model: Evidence for distinct cellular progenitors of the ductal and lobular phenotype
    • G.H. Smith, Experimental mammary epithelial morphogenesis in an in vivo model: Evidence for distinct cellular progenitors of the ductal and lobular phenotype, Breast Cancer Res Treat 39 (1996), 21-31.
    • (1996) Breast Cancer Res Treat , vol.39 , pp. 21-31
    • Smith, G.H.1
  • 22
    • 0031748344 scopus 로고    scopus 로고
    • An entire functional mammary gland may comprise the progeny from a single cell
    • E.C. Kordon and G.H. Smith, An entire functional mammary gland may comprise the progeny from a single cell, Development 125 (1998), 1921-1930.
    • (1998) Development , vol.125 , pp. 1921-1930
    • Kordon, E.C.1    Smith, G.H.2
  • 23
    • 0032618540 scopus 로고    scopus 로고
    • Mammary epithelial stem cells: Our current understanding
    • G. Chepko and G.H. Smith, Mammary epithelial stem cells: Our current understanding, J Mammary Gland Biol Neoplasia 4 (1999), 35-52.
    • (1999) J Mammary Gland Biol Neoplasia , vol.4 , pp. 35-52
    • Chepko, G.1    Smith, G.H.2
  • 24
    • 0035863008 scopus 로고    scopus 로고
    • Mammary epithelial stem cells
    • G.H. Smith and G. Chepko, Mammary epithelial stem cells, Microsc Res Tech 52 (2001), 190-203.
    • (2001) Microsc Res Tech , vol.52 , pp. 190-203
    • Smith, G.H.1    Chepko, G.2
  • 25
    • 1542358839 scopus 로고    scopus 로고
    • A molecular view of stem cell and cancer cell self-renewal
    • R.Y. Tsai, A molecular view of stem cell and cancer cell self-renewal, Int J Biochem Cell Biol 36 (2004), 684-694.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 684-694
    • Tsai, R.Y.1
  • 26
    • 14844343185 scopus 로고    scopus 로고
    • Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands
    • G.H. Smith, Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands, Development 132 (2005), 681-687.
    • (2005) Development , vol.132 , pp. 681-687
    • Smith, G.H.1
  • 27
    • 0001397342 scopus 로고    scopus 로고
    • Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth
    • N. Zeps, J.M. Bentel, J.M. Papadimitriou, M.F. D'Antuono and H.J. Dawkins, Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth, Differentiation 62 (1998), 221-226.
    • (1998) Differentiation , vol.62 , pp. 221-226
    • Zeps, N.1    Bentel, J.M.2    Papadimitriou, J.M.3    D'Antuono, M.F.4    Dawkins, H.J.5
  • 28
    • 33748134717 scopus 로고    scopus 로고
    • Estrogen receptor-alpha and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands
    • B.W. Booth and G.H. Smith, Estrogen receptor-alpha and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands, Breast Cancer Res 8 (2006), R49.
    • (2006) Breast Cancer Res , vol.8
    • Booth, B.W.1    Smith, G.H.2
  • 29
    • 11144340909 scopus 로고    scopus 로고
    • A putative human breast stem cell population is enriched for steroid receptor-positive cells
    • R.B. Clarke, K. Spence, E. Anderson, A. Howell, H. Okano and C.S. Potten, A putative human breast stem cell population is enriched for steroid receptor-positive cells, Dev Biol 277 (2005), 443-456.
    • (2005) Dev Biol , vol.277 , pp. 443-456
    • Clarke, R.B.1    Spence, K.2    Anderson, E.3    Howell, A.4    Okano, H.5    Potten, C.S.6
  • 30
    • 33845982922 scopus 로고    scopus 로고
    • Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland
    • K.E. Sleeman, H. Kerdrick, D. Robertson, C.M. Isacke, A. Ashworth and M.J. Smalley Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland, J Cell Biol 176 (2007), 19-26.
    • (2007) J Cell Biol , vol.176 , pp. 19-26
    • Sleeman, K.E.1    Kerdrick, H.2    Robertson, D.3    Isacke, C.M.4    Ashworth, A.5    Smalley, M.J.6
  • 31
    • 19944428193 scopus 로고    scopus 로고
    • Evidence for early life roots of human cancer
    • Association of fetal hormone levels with stem cell potential
    • I. Baik, W.J. Devito, K. Ballen et al., Association of fetal hormone levels with stem cell potential: Evidence for early life roots of human cancer, Cancer Res 65 (2005), 358-363.
    • (2005) Cancer Res , vol.65 , pp. 358-363
    • Baik, I.1    Devito, W.J.2    Ballen, K.3
  • 32
    • 0029958876 scopus 로고    scopus 로고
    • isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • M.A. Goodell, K. Brose, G. Paradis, A.S. Conner and R.C. Mulligan, isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo, J Exp Med 183 (1996), 1797-1806.
    • (1996) J Exp Med , vol.183 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 33
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
    • S. Zhou, J.D. Schuetz, K.D. Buitting et al., The ABC transporter Bcrp1/ ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype, Nat Med 7 (2001),1028-1034.
    • (2001) Nat Med , vol.7 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Buitting, K.D.3
  • 34
    • 0036570144 scopus 로고    scopus 로고
    • Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population
    • B.E. Welm, S.B. Tepera, T. Venezia, T.A. Graubert, J.M. Rosen and M.A. Goodell, Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population, Dev Biol 245 (2002), 42-56.
    • (2002) Dev Biol , vol.245 , pp. 42-56
    • Welm, B.E.1    Tepera, S.B.2    Venezia, T.3    Graubert, T.A.4    Rosen, J.M.5    Goodell, M.A.6
  • 35
    • 1642486729 scopus 로고    scopus 로고
    • Functional and molecular characterisation of mammary side population cells
    • A.J. Alvi, H. Clayton, C. Joshi et al., Functional and molecular characterisation of mammary side population cells, Breast Cancer Res 5 (2003), R1-R8.
    • (2003) Breast Cancer Res , vol.5
    • Alvi, A.J.1    Clayton, H.2    Joshi, C.3
  • 36
    • 2942590202 scopus 로고    scopus 로고
    • ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status
    • N. Uchida, B. Dykstra, K. Lyons, F. Leung, M. Kristiansen and C. Eaves, ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status, Blood 103 (2004), 4487-4495.
    • (2004) Blood , vol.103 , pp. 4487-4495
    • Uchida, N.1    Dykstra, B.2    Lyons, K.3    Leung, F.4    Kristiansen, M.5    Eaves, C.6
  • 37
    • 0036339643 scopus 로고    scopus 로고
    • An adjunct mammary epithelial cell population in parous females: Its role in functional adaptation and tissue renewal
    • K.U. Wagner, C.A. Boulanger, M.D. Henry, M. Sgagias, L, Hennighausen and G.H. Smith, An adjunct mammary epithelial cell population in parous females: Its role in functional adaptation and tissue renewal, Development 129 (2002), 1377-1386.
    • (2002) Development , vol.129 , pp. 1377-1386
    • Wagner, K.U.1    Boulanger, C.A.2    Henry, M.D.3    Sgagias, M.4    Hennighausen, L.5    Smith, G.H.6
  • 38
    • 0036965928 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol-anchored proteins: Structure, function, and cleavage by phosphatidylinositol-specific phospholipase C
    • F.J. Sharom and M.T. Lehto, Glycosylphosphatidylinositol-anchored proteins: Structure, function, and cleavage by phosphatidylinositol-specific phospholipase C, Biochem Cell Biol 80 (2002), 535-549.
    • (2002) Biochem Cell Biol , vol.80 , pp. 535-549
    • Sharom, F.J.1    Lehto, M.T.2
  • 39
    • 1842411942 scopus 로고
    • Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family
    • M. van de Rijn, S. Heimfeld, G.J. Spangrude and I.L. Weissman, Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family, Proc Natl Acad Sci USA 86 (1989), 4634-4638.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 4634-4638
    • van de Rijn, M.1    Heimfeld, S.2    Spangrude, G.J.3    Weissman, I.L.4
  • 40
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • J.E. Darrnell Jr., I.M. Kerr and G.R. Stark, Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins, Science 764 (1994), 1415-1421.
    • (1994) Science , vol.764 , pp. 1415-1421
    • Darrnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 41
    • 0027430972 scopus 로고
    • Cloning of the complete Ly-6E.1 gene and identification of DNase I hypersensitive sites corresponding to expression in hematopoietic cells
    • A.M. Sinclair and E.A. Dzierzak, Cloning of the complete Ly-6E.1 gene and identification of DNase I hypersensitive sites corresponding to expression in hematopoietic cells, Blood 82 (1993), 3052-3062.
    • (1993) Blood , vol.82 , pp. 3052-3062
    • Sinclair, A.M.1    Dzierzak, E.A.2
  • 42
    • 0026090037 scopus 로고
    • The glycosyl phosphatidylinositol anchor is critical for Ly-6A/E- mediated T cell activation
    • B. Su, G.L. Waneck, R.A. Flavell and A.L. Bothwell, The glycosyl phosphatidylinositol anchor is critical for Ly-6A/E- mediated T cell activation, J Cell Biol 112 (1991), 377-384.
    • (1991) J Cell Biol , vol.112 , pp. 377-384
    • Su, B.1    Waneck, G.L.2    Flavell, R.A.3    Bothwell, A.L.4
  • 43
    • 0345414164 scopus 로고    scopus 로고
    • Activation induced differential regulation of stem cell antigen-1 (Ly-6A/E) expression in murine B cells
    • H.C. Chen, F. Frissora, J.E. Durbin and N. Muthusamy, Activation induced differential regulation of stem cell antigen-1 (Ly-6A/E) expression in murine B cells, Cell Immunol 225 (2003), 42-52.
    • (2003) Cell Immunol , vol.225 , pp. 42-52
    • Chen, H.C.1    Frissora, F.2    Durbin, J.E.3    Muthusamy, N.4
  • 44
    • 0344483905 scopus 로고    scopus 로고
    • Complex regulation of Ly-6E gene transcription in T cells by IFNS
    • M.M. Khodadoust, K.D. Khan and A.L. Bothwell, Complex regulation of Ly-6E gene transcription in T cells by IFNS, J Immunol 163 (1999), 811-819.
    • (1999) J Immunol , vol.163 , pp. 811-819
    • Khodadoust, M.M.1    Khan, K.D.2    Bothwell, A.L.3
  • 45
    • 0034786210 scopus 로고    scopus 로고
    • Cloning of the Ly-6A (Sca-1) gene locus and identification of a 3′ distal fragment responsible for high-level gamma-interferon-induced expression in vitro
    • X. Ma, K.W. Ling and E. Dzierzak, Cloning of the Ly-6A (Sca-1) gene locus and identification of a 3′ distal fragment responsible for high-level gamma-interferon-induced expression in vitro, Br J Haematol 114 (2001), 724-730.
    • (2001) Br J Haematol , vol.114 , pp. 724-730
    • Ma, X.1    Ling, K.W.2    Dzierzak, E.3
  • 46
    • 0027496114 scopus 로고
    • A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
    • H.B. Sadowski, K. Shuaj, J.E. Darnell Jr. and M.Z. Gilman, A common nuclear signal transduction pathway activated by growth factor and cytokine receptors, Science 261 (1993), 1739-1744.
    • (1993) Science , vol.261 , pp. 1739-1744
    • Sadowski, H.B.1    Shuaj, K.2    Darnell Jr., J.E.3    Gilman, M.Z.4
  • 47
    • 21144458217 scopus 로고    scopus 로고
    • Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function
    • A. Linke, P. Muller, D. Nurzynska et al., Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function, Proc Natl Acad Sci USA 102 (2005), 8966-8971.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8966-8971
    • Linke, A.1    Muller, P.2    Nurzynska, D.3
  • 49
    • 19444385094 scopus 로고    scopus 로고
    • Stem/progenitor cells in mouse mammary gland development and breast cancer
    • Y. Li and J.M. Rosen, Stem/progenitor cells in mouse mammary gland development and breast cancer, J Mammary Gland Biol Neoplasia 10 (2005), 17-24.
    • (2005) J Mammary Gland Biol Neoplasia , vol.10 , pp. 17-24
    • Li, Y.1    Rosen, J.M.2
  • 50
    • 8144229020 scopus 로고    scopus 로고
    • Expression of the hematopoietic stem cell antigen Sca-1 (LY-6A/E) in liver sinusoidal endothelial cells: Possible function of Sca-1 in endothelial cells
    • G. Luna, J. Paez and I.E. Cardier, Expression of the hematopoietic stem cell antigen Sca-1 (LY-6A/E) in liver sinusoidal endothelial cells: possible function of Sca-1 in endothelial cells, Stem Cells Dev 13 (2004), 528-535.
    • (2004) Stem Cells Dev , vol.13 , pp. 528-535
    • Luna, G.1    Paez, J.2    Cardier, I.E.3
  • 51
    • 18844424692 scopus 로고    scopus 로고
    • Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue
    • P.E. Burger, X. Xiong, S. Coetzee et al., Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue, Proc Natl Acad Sci USA 102 (2005), 7180-7185.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7180-7185
    • Burger, P.E.1    Xiong, X.2    Coetzee, S.3
  • 52
    • 0022500156 scopus 로고
    • Role of Ly-6 in lymphocyte activation. II. Induction of T cell activation by monoclonal anti-Ly-6 antibodies
    • T.R. Malek, G. Ortega, C. Chan, R.A. Kroczek and E.M. Shevach, Role of Ly-6 in lymphocyte activation. II. Induction of T cell activation by monoclonal anti-Ly-6 antibodies, J Exp Med 164 (1986), 709-722.
    • (1986) J Exp Med , vol.164 , pp. 709-722
    • Malek, T.R.1    Ortega, G.2    Chan, C.3    Kroczek, R.A.4    Shevach, E.M.5
  • 53
    • 12344337753 scopus 로고    scopus 로고
    • Stem cell antigen-1 is necessary for cell-cycle withdrawal and myoblast differentiation in C2C12 cells
    • C.L. Epting, J.E. Lopez, X. Shen, L. Liu, J. Bristow and H.S. Bernstein, Stem cell antigen-1 is necessary for cell-cycle withdrawal and myoblast differentiation in C2C12 cells, J Cell Sci 117 (2004), 6185-6195.
    • (2004) J Cell Sci , vol.117 , pp. 6185-6195
    • Epting, C.L.1    Lopez, J.E.2    Shen, X.3    Liu, L.4    Bristow, J.5    Bernstein, H.S.6
  • 54
    • 0028800787 scopus 로고
    • Structure of the human urokinase receptor gene and its similarity to CD59 and the Ly-6 family
    • Y. Wang, J. Dang, L.K. Johnson, J.J. Selhamer and W.F. Doe, Structure of the human urokinase receptor gene and its similarity to CD59 and the Ly-6 family, Eur J Biochem 227 (1995), 116-122.
    • (1995) Eur J Biochem , vol.227 , pp. 116-122
    • Wang, Y.1    Dang, J.2    Johnson, L.K.3    Selhamer, J.J.4    Doe, W.F.5
  • 55
    • 20444469154 scopus 로고    scopus 로고
    • Roles of Sca-1 in hematopoietic stem/progenitor cell function
    • S.B. Bradfute, T.A. Graubert and M.A. Goodell, Roles of Sca-1 in hematopoietic stem/progenitor cell function, Exp Hematol 33 (2005), 836-843.
    • (2005) Exp Hematol , vol.33 , pp. 836-843
    • Bradfute, S.B.1    Graubert, T.A.2    Goodell, M.A.3
  • 56
    • 0036134851 scopus 로고    scopus 로고
    • Ly-6A.2 expression regulates antigen-specific CD4+ T cell proliferation and cytokine production
    • S.C. Henderson, M.M. Kamdar and A. Bamezai, Ly-6A.2 expression regulates antigen-specific CD4+ T cell proliferation and cytokine production, J Immunol 168 (2002), 118-126.
    • (2002) J Immunol , vol.168 , pp. 118-126
    • Henderson, S.C.1    Kamdar, M.M.2    Bamezai, A.3
  • 57
    • 0028053270 scopus 로고
    • The role of CD4+ and CD8+ T cells in the protective inflammatory response to a pulmonary cryptococcal infection
    • G.B. Huffnagle, M.F. Lipscomb, J.A. Lovchik, K.A. Hoag and N.E. Street, The role of CD4+ and CD8+ T cells in the protective inflammatory response to a pulmonary cryptococcal infection, J Leukoc Biol 55 (1994), 35-42.
    • (1994) J Leukoc Biol , vol.55 , pp. 35-42
    • Huffnagle, G.B.1    Lipscomb, M.F.2    Lovchik, J.A.3    Hoag, K.A.4    Street, N.E.5
  • 58
    • 0030880999 scopus 로고    scopus 로고
    • Altered proliferative response by T lymphocytes of Ly-6A (Sca-1) null mice
    • W.L. Stanford, S. Haque, R. Alexander et al., Altered proliferative response by T lymphocytes of Ly-6A (Sca-1) null mice, J Exp Med 186 (1997), 705-717.
    • (1997) J Exp Med , vol.186 , pp. 705-717
    • Stanford, W.L.1    Haque, S.2    Alexander, R.3
  • 59
    • 0036080434 scopus 로고    scopus 로고
    • Ly-6A is critical for the function of double negative regulatory T cells
    • Z.X. Zhang, W.L. Stanford and L. Zhang, Ly-6A is critical for the function of double negative regulatory T cells, Eur J Immunol 32 (2002), 1584-1592.
    • (2002) Eur J Immunol , vol.32 , pp. 1584-1592
    • Zhang, Z.X.1    Stanford, W.L.2    Zhang, L.3
  • 60
    • 0037449167 scopus 로고    scopus 로고
    • Differentiation of bone marrow cells into cells that express liver-specific genes in vitro: Implication of the Notch signals in differentiation
    • K. Okumoto, T. Saito, E. Hattori et al., Differentiation of bone marrow cells into cells that express liver-specific genes in vitro: implication of the Notch signals in differentiation, Biochem Biophys Res Commun 304 (2003), 691-695.
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 691-695
    • Okumoto, K.1    Saito, T.2    Hattori, E.3
  • 61
    • 0346244093 scopus 로고    scopus 로고
    • Isolation and characterization of functional mammary gland stem cells
    • B. Welm, F. Behbod, M.A. Goodell and J.M. Rosen, Isolation and characterization of functional mammary gland stem cells, Cell Prolif 36(Suppl 1) (2003), 17-32.
    • (2003) Cell Prolif , vol.36 , Issue.SUPPL. 1 , pp. 17-32
    • Welm, B.1    Behbod, F.2    Goodell, M.A.3    Rosen, J.M.4
  • 62
    • 0037314861 scopus 로고    scopus 로고
    • Enhanced green fluorescent protein targeted to the Sca-1 (Ly-6A) locus in transgenic mice results in efficient marking of hematopoietic stem cells in vivo
    • P. Hanson, V. Mathews, S.H. Marrus and T.A. Graubert, Enhanced green fluorescent protein targeted to the Sca-1 (Ly-6A) locus in transgenic mice results in efficient marking of hematopoietic stem cells in vivo, Exp Hematol 31 (2003), 159-167.
    • (2003) Exp Hematol , vol.31 , pp. 159-167
    • Hanson, P.1    Mathews, V.2    Marrus, S.H.3    Graubert, T.A.4
  • 63
    • 0242667837 scopus 로고    scopus 로고
    • Stem cells and breast cancer: A field in transit
    • M. Smalley and A. Ashworth, Stem cells and breast cancer: A field in transit, Nat Rev Cancer 3 (2003), 832-844.
    • (2003) Nat Rev Cancer , vol.3 , pp. 832-844
    • Smalley, M.1    Ashworth, A.2
  • 64
    • 18744377702 scopus 로고    scopus 로고
    • The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis
    • L. Xin, D.A. Lawson and O.N. Witte, The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis, Proc Natl Acad Sci USA 102 (2005), 6942-6947.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 6942-6947
    • Xin, L.1    Lawson, D.A.2    Witte, O.N.3
  • 65
    • 33846659953 scopus 로고    scopus 로고
    • Sensitive ChIP-DSL technology reveals an extensive estrogen receptor {alpha}-binding program on human gene promoters
    • Y.S. Kwon, I. Garcia-Bassets, K.R. Hutt et al., Sensitive ChIP-DSL technology reveals an extensive estrogen receptor {alpha}-binding program on human gene promoters, Proc Natl Acad Sci USA 104 (2007), 4852-4857.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4852-4857
    • Kwon, Y.S.1    Garcia-Bassets, I.2    Hutt, K.R.3
  • 66
    • 41849117253 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptory is a regulator of mammary stem and progenitor cell self-renewal and estrogen receptor-dependent tumor specification
    • Los Angeles, CA, April 14-18
    • Y. Yin, H. Yuan, S. Mueller, L. Kopelovich and R.I. Glazer, Peroxisome proliferator-activated receptory is a regulator of mammary stem and progenitor cell self-renewal and estrogen receptor-dependent tumor specification. Proceedings of the American Association for Cancer Research, Los Angeles, CA, April 14-18, 2007.
    • (2007) Proceedings of the American Association for Cancer Research
    • Yin, Y.1    Yuan, H.2    Mueller, S.3    Kopelovich, L.4    Glazer, R.I.5
  • 67
    • 33750470097 scopus 로고    scopus 로고
    • CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells
    • K.E. Sleeman, H. Kendrick, A. Ashworth, C.M. Isacke and M.J. Smalley, CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells, Breast Cancer Res 8 (2006), R7.
    • (2006) Breast Cancer Res , vol.8
    • Sleeman, K.E.1    Kendrick, H.2    Ashworth, A.3    Isacke, C.M.4    Smalley, M.J.5
  • 68
    • 33746709476 scopus 로고    scopus 로고
    • Steroid hormone receptor status of mouse mammary stem cells
    • M.L. Asselin-Labat, M. Shackleton, J. Stingl et al., Steroid hormone receptor status of mouse mammary stem cells, J Natl Cancer Inst 98 (2006), 1011-1014.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1011-1014
    • Asselin-Labat, M.L.1    Shackleton, M.2    Stingl, J.3
  • 69
    • 30144433093 scopus 로고    scopus 로고
    • Generation of a functional mammary gland from a single stem cell
    • M. Shackleton, F. Vaillant, K.J. Simpson et al.. Generation of a functional mammary gland from a single stem cell, Nature 439 (2006), 84-88.
    • (2006) Nature , vol.439 , pp. 84-88
    • Shackleton, M.1    Vaillant, F.2    Simpson, K.J.3
  • 70
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • J. Stingl, P. Eirew, I. Ricketson et al., Purification and unique properties of mammary epithelial stem cells, Nature 439 (2006), 993-997.
    • (2006) Nature , vol.439 , pp. 993-997
    • Stingl, J.1    Eirew, P.2    Ricketson, I.3
  • 72
    • 21344454219 scopus 로고    scopus 로고
    • Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
    • D. Ponti, A. Costa, N. Zaffaroni et al., Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties, Cancer Res 65 (2005), 5506-5511.
    • (2005) Cancer Res , vol.65 , pp. 5506-5511
    • Ponti, D.1    Costa, A.2    Zaffaroni, N.3
  • 73
    • 33846425793 scopus 로고    scopus 로고
    • The prognostic role of a gene signature from tumorigenic breast-cancer cells
    • R. Liu, X. Wang, G.Y. Chen et al., The prognostic role of a gene signature from tumorigenic breast-cancer cells, N Engl J Med 356 (2007), 217-226.
    • (2007) N Engl J Med , vol.356 , pp. 217-226
    • Liu, R.1    Wang, X.2    Chen, G.Y.3
  • 74
    • 33847419142 scopus 로고    scopus 로고
    • Molecular definition of breast tumor heterogeneity
    • M. Shipitsin, L.L. Campbell, P. Argani et al., Molecular definition of breast tumor heterogeneity, Cancer Cell 11 (2007), 259-273.
    • (2007) Cancer Cell , vol.11 , pp. 259-273
    • Shipitsin, M.1    Campbell, L.L.2    Argani, P.3
  • 75
    • 0345059767 scopus 로고    scopus 로고
    • Applying the principles of stem-cell biology to cancer
    • R. Pardal, M.F. Clarke and S.J. Morrison, Applying the principles of stem-cell biology to cancer, Nat Rev Cancer 3 (2003), 895-902.
    • (2003) Nat Rev Cancer , vol.3 , pp. 895-902
    • Pardal, R.1    Clarke, M.F.2    Morrison, S.J.3
  • 76
    • 0037376416 scopus 로고    scopus 로고
    • An overview of the Notch signalling pathway
    • M. Baron, An overview of the Notch signalling pathway, Semin Cell Dev Biol 14 (2003), 113-119.
    • (2003) Semin Cell Dev Biol , vol.14 , pp. 113-119
    • Baron, M.1
  • 77
    • 0036537894 scopus 로고    scopus 로고
    • Musashi: A translational regulator of cell fate
    • H. Okano, T. Imai and M. Okabe, Musashi: A translational regulator of cell fate, J Cell Sci 115 (2002), 1355-1359.
    • (2002) J Cell Sci , vol.115 , pp. 1355-1359
    • Okano, H.1    Imai, T.2    Okabe, M.3
  • 78
    • 0037663379 scopus 로고    scopus 로고
    • Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain
    • M.A. McGill and C.J. McGlade, Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain, J Biol Chem (2003).
    • (2003) J Biol Chem
    • McGill, M.A.1    McGlade, C.J.2
  • 79
    • 0033136704 scopus 로고    scopus 로고
    • NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1
    • Y. Wakamatsu, T.M. Maynard, S.U. Jones and J.A. Weston, NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1, Neuron 23 (1999), 71-81.
    • (1999) Neuron , vol.23 , pp. 71-81
    • Wakamatsu, Y.1    Maynard, T.M.2    Jones, S.U.3    Weston, J.A.4
  • 80
    • 0035016795 scopus 로고    scopus 로고
    • The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA
    • T. Imai, A. Tokunaga, T. Yoshida et al., The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA, Mol Cell Biol 21 (2001), 3888-3900.
    • (2001) Mol Cell Biol , vol.21 , pp. 3888-3900
    • Imai, T.1    Tokunaga, A.2    Yoshida, T.3
  • 81
    • 30044442091 scopus 로고    scopus 로고
    • The RNA-binding protein Musashi-1 regulates neural development through the translational repression of p21WAF-1
    • C. Battelli, G.N. Nikopoulos, J.G. Mitchell and J.M. Verdi, The RNA-binding protein Musashi-1 regulates neural development through the translational repression of p21WAF-1, Mol Cell Neurosci 31 (2006), 85-96.
    • (2006) Mol Cell Neurosci , vol.31 , pp. 85-96
    • Battelli, C.1    Nikopoulos, G.N.2    Mitchell, J.G.3    Verdi, J.M.4
  • 82
    • 7244250027 scopus 로고    scopus 로고
    • Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
    • S. Pece, M. Serresi, E. Santolini et al., Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis, J Cell Biol 167 (2004), 215-221.
    • (2004) J Cell Biol , vol.167 , pp. 215-221
    • Pece, S.1    Serresi, M.2    Santolini, E.3
  • 83
    • 32944470488 scopus 로고    scopus 로고
    • Aberrant activation of notch signaling in human breast cancer
    • S. Stylianou, R.B. Clarke and K. Brennan, Aberrant activation of notch signaling in human breast cancer, Cancer Res 66 (2006), 1517-1525.
    • (2006) Cancer Res , vol.66 , pp. 1517-1525
    • Stylianou, S.1    Clarke, R.B.2    Brennan, K.3
  • 84
    • 20244365304 scopus 로고    scopus 로고
    • Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell
    • S. Sakakibara, T. Imai, K. Hamaguchi et al., Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell, Dev Biol 176 (1996), 230-242.
    • (1996) Dev Biol , vol.176 , pp. 230-242
    • Sakakibara, S.1    Imai, T.2    Hamaguchi, K.3
  • 85
    • 0346244047 scopus 로고    scopus 로고
    • Regulation of human breast epithelial stem ceils
    • R.B. Clarke, E. Anderson, A. Howell and C.S. Potten, Regulation of human breast epithelial stem ceils, Ceil Prolif 36(Suppl 1) (2003), 45-58.
    • (2003) Ceil Prolif , vol.36 , Issue.SUPPL. 1 , pp. 45-58
    • Clarke, R.B.1    Anderson, E.2    Howell, A.3    Potten, C.S.4
  • 86
    • 0034738965 scopus 로고    scopus 로고
    • Ras pathway signals are required for notch-mediated oncogenesis
    • K. Fitzgerald, A. Harrington and P. Leder, Ras pathway signals are required for notch-mediated oncogenesis, Oncogene 19 (2000 , 4191-4198.
    • (2000) Oncogene , vol.19 , pp. 4191-4198
    • Fitzgerald, K.1    Harrington, A.2    Leder, P.3
  • 87
    • 0026517312 scopus 로고
    • Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands
    • C. Jhappan, D. Gallahan, C. Stahle et al., Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands, Genes Dev 6 (1992), 345-355.
    • (1992) Genes Dev , vol.6 , pp. 345-355
    • Jhappan, C.1    Gallahan, D.2    Stahle, C.3
  • 88
    • 33644660241 scopus 로고    scopus 로고
    • Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors
    • C. Hu, A. Dievart, M. Lupien, E. Calvo, G. Tremblay and P. Jolicoeur, Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors, Am J Pathol 168 (2006), 973-990.
    • (2006) Am J Pathol , vol.168 , pp. 973-990
    • Hu, C.1    Dievart, A.2    Lupien, M.3    Calvo, E.4    Tremblay, G.5    Jolicoeur, P.6
  • 89
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • G. Dontu, W.M. Abdallah, J.M. Foley et al., In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells, Genes Dev 17 (2003), 1253-1270.
    • (2003) Genes Dev , vol.17 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3
  • 91
    • 0028970950 scopus 로고
    • Transforming growth factor-alpha promotes mammary tumorigenesis through selective survival and growth of secretory epithelial cells
    • G.H. Smith, R. Sharp, E.C. Kordon, C. Jhappan and G. Merlino, Transforming growth factor-alpha promotes mammary tumorigenesis through selective survival and growth of secretory epithelial cells, Am J Pathol 147 (1995), 1081-1096.
    • (1995) Am J Pathol , vol.147 , pp. 1081-1096
    • Smith, G.H.1    Sharp, R.2    Kordon, E.C.3    Jhappan, C.4    Merlino, G.5
  • 92
    • 28544452194 scopus 로고    scopus 로고
    • Isolation and characterization of human mammary stem cells
    • R.B. Clarke, Isolation and characterization of human mammary stem cells, Cell Prolif 38 (2005), 375-386.
    • (2005) Cell Prolif , vol.38 , pp. 375-386
    • Clarke, R.B.1
  • 93
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • T. Reya and H. Clevers, Wnt signalling in stem cells and cancer, Nature 434 (2005), 843-850.
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 94
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of beta-catenin with the transcription factor LEF-1
    • J. Behrens, J.P. von Kries, M. Kuhl et al., Functional interaction of beta-catenin with the transcription factor LEF-1, Nature 382 (1996), 638-642.
    • (1996) Nature , vol.382 , pp. 638-642
    • Behrens, J.1    von Kries, J.P.2    Kuhl, M.3
  • 95
    • 33747339465 scopus 로고    scopus 로고
    • Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors
    • M.D. Gordon and R. Nusse, Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors, J Biol Chem 281 (2006), 22429-22433.
    • (2006) J Biol Chem , vol.281 , pp. 22429-22433
    • Gordon, M.D.1    Nusse, R.2
  • 96
    • 0035902140 scopus 로고    scopus 로고
    • The Hedgehog and Wnt signalling pathways in cancer
    • J. Taipale and P.A. Beachy, The Hedgehog and Wnt signalling pathways in cancer, Nature 411 (2001), 349-354.
    • (2001) Nature , vol.411 , pp. 349-354
    • Taipale, J.1    Beachy, P.A.2
  • 98
    • 0020216124 scopus 로고
    • Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
    • R. Nusse and H.E. Varmus, Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome, Cell 31 (1982), 99-109.
    • (1982) Cell , vol.31 , pp. 99-109
    • Nusse, R.1    Varmus, H.E.2
  • 99
    • 0030779038 scopus 로고    scopus 로고
    • Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin
    • K. Orford, C. Crockett, J.P. Jensen, A.M. Weissman and S.W. Byers, Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin, J Biol Chem 272 (1997), 24735-24738.
    • (1997) J Biol Chem , vol.272 , pp. 24735-24738
    • Orford, K.1    Crockett, C.2    Jensen, J.P.3    Weissman, A.M.4    Byers, S.W.5
  • 100
    • 0029811434 scopus 로고    scopus 로고
    • Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C
    • D. Cook, M.J. Fry, K. Hughes, R. Sumathipala, J.R. Woodgett and T.C. Dale, Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C, Embo J 15 (1996), 4526-4536.
    • (1996) Embo J , vol.15 , pp. 4526-4536
    • Cook, D.1    Fry, M.J.2    Hughes, K.3    Sumathipala, R.4    Woodgett, J.R.5    Dale, T.C.6
  • 101
    • 0034625355 scopus 로고    scopus 로고
    • Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C
    • R.H. Chen, W.V. Ding and F. McCormick, Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C, J Biol Chem 275 (2000), 17894-17899.
    • (2000) J Biol Chem , vol.275 , pp. 17894-17899
    • Chen, R.H.1    Ding, W.V.2    McCormick, F.3
  • 102
    • 34447122100 scopus 로고    scopus 로고
    • A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK Pathways
    • D. Kim, O. Rath, W. Kolch and K.H. Cho, A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK Pathways, Oncogene (2007).
    • (2007) Oncogene
    • Kim, D.1    Rath, O.2    Kolch, W.3    Cho, K.H.4
  • 103
    • 0035972159 scopus 로고    scopus 로고
    • Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland
    • A. Imbert, R. Eelkema, S. Jordan, H. Feiner and P. Cowin, Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland, J Cell Biol 153 (2001), 555-568.
    • (2001) J Cell Biol , vol.153 , pp. 555-568
    • Imbert, A.1    Eelkema, R.2    Jordan, S.3    Feiner, H.4    Cowin, P.5
  • 104
    • 0024162530 scopus 로고
    • Expression the int-i gene in transgenic mice is associated with manimary gland hyperplasia and adenocarcinomas in male and female mice
    • A.S. Tsukamoto, R. Grosschedl, R.C. Guzman, T. Parslow and H.E. Varinus, Expression the int-i gene in transgenic mice is associated with manimary gland hyperplasia and adenocarcinomas in male and female mice, Cell 55 (1988), 619-625.
    • (1988) Cell , vol.55 , pp. 619-625
    • Tsukamoto, A.S.1    Grosschedl, R.2    Guzman, R.C.3    Parslow, T.4    Varinus, H.E.5
  • 105
    • 33646581038 scopus 로고    scopus 로고
    • 3-Phosphoinositide-dependent Protein Kinase-1 (PDKI) Promotes Invasion and Activation of Matrix Metalloproteinases
    • Z. Xie, H. Yuan, Y Yin, X. Zeng, R. Bai and R.I. Glazer, 3-Phosphoinositide-dependent Protein Kinase-1 (PDKI) Promotes Invasion and Activation of Matrix Metalloproteinases, BMC Cancer 6 (2006), 77.
    • (2006) BMC Cancer , vol.6 , pp. 77
    • Xie, Z.1    Yuan, H.2    Yin, Y.3    Zeng, X.4    Bai, R.5    Glazer, R.I.6
  • 106
    • 0141816833 scopus 로고    scopus 로고
    • Transformation of mammary epithelial cells by 3-phosphoinositide- dependent protein kinase-1 activates beta-catenin and c-Myc, and down-regulates caveolin-1
    • Z. Xie, X. Zeng, T. Waldman and R.I. Glazer, Transformation of mammary epithelial cells by 3-phosphoinositide- dependent protein kinase-1 activates beta-catenin and c-Myc, and down-regulates caveolin-1, Cancer Res 63 (2003), 5370-5375.
    • (2003) Cancer Res , vol.63 , pp. 5370-5375
    • Xie, Z.1    Zeng, X.2    Waldman, T.3    Glazer, R.I.4
  • 107
    • 0037096904 scopus 로고    scopus 로고
    • Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 (PDK1) is associated with the induction of prolein kinase Cα
    • X. Zeng, H. Xu, B.-K. Park and R.I. Glazer, Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 (PDK1) is associated with the induction of prolein kinase Cα, Cancer Res 62 (2002), 3538-3543.
    • (2002) Cancer Res , vol.62 , pp. 3538-3543
    • Zeng, X.1    Xu, H.2    Park, B.-K.3    Glazer, R.I.4
  • 109
    • 9144269759 scopus 로고    scopus 로고
    • Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
    • Y. Li, B. Welm, K. Podsypanina et al., Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells, Proc Natl Acad Sci USA 100 (2003), 15853-15858.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15853-15858
    • Li, Y.1    Welm, B.2    Podsypanina, K.3
  • 110
    • 1642570244 scopus 로고    scopus 로고
    • The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells
    • B.Y. Liu, S.P. McDermott, S.S. Khwaja and C.M. Alexander, The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells, Proc Natl Acad Sci USA 101 (2004), 4158-4163.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4158-4163
    • Liu, B.Y.1    McDermott, S.P.2    Khwaja, S.S.3    Alexander, C.M.4
  • 111
    • 0033919506 scopus 로고    scopus 로고
    • Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium
    • S. Naylor, M.J. Smalley, D. Robertson, B.A. Gusterson, P.A. Edwards and T.C. Dale, Retroviral expression of Wnt-1 and Wnt-7b produces different effects in mouse mammary epithelium, J Cell Sci 113(Pt 12) (2000), 2129-2138.
    • (2000) J Cell Sci , vol.113 , Issue.PART 12 , pp. 2129-2138
    • Naylor, S.1    Smalley, M.J.2    Robertson, D.3    Gusterson, B.A.4    Edwards, P.A.5    Dale, T.C.6
  • 112
    • 34248393912 scopus 로고    scopus 로고
    • Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency
    • T. Miyabayashi, J.L. Teo, M. Yamamoto, M. McMillan, C. Nguyen and M. Kahn, Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency, Proc Natl Acad Sci USA 104 (2007), 5668-5673.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5668-5673
    • Miyabayashi, T.1    Teo, J.L.2    Yamamoto, M.3    McMillan, M.4    Nguyen, C.5    Kahn, M.6
  • 113
    • 4444342868 scopus 로고    scopus 로고
    • Expression profiling and functional analysis of wnt signaling mechaisms in mesenchymal stem cells
    • S.L. Etheridge, G.J. Spencer, D.J. Heath and P.G. Genever, Expression profiling and functional analysis of wnt signaling mechaisms in mesenchymal stem cells, Stem Cells 22 (2004), 849-860.
    • (2004) Stem Cells , vol.22 , pp. 849-860
    • Etheridge, S.L.1    Spencer, G.J.2    Heath, D.J.3    Genever, P.G.4
  • 114
  • 115
  • 116
    • 0347753697 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptors and cancers: Complex stories
    • L. Michalik, B. Desvergne and W. Wahli, Peroxisome-proliferator-activated receptors and cancers: Complex stories, Nat Rev Cancer 4 (2004), 61-70.
    • (2004) Nat Rev Cancer , vol.4 , pp. 61-70
    • Michalik, L.1    Desvergne, B.2    Wahli, W.3
  • 117
    • 3042815666 scopus 로고    scopus 로고
    • Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists
    • C. Grommes. G.E. Landreth and M.T. Heneka, Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists, Lancet Oncol 5 (2004), 419-429.
    • (2004) Lancet Oncol , vol.5 , pp. 419-429
    • Grommes, C.1    Landreth, G.E.2    Heneka, M.T.3
  • 118
    • 0029067225 scopus 로고
    • Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements
    • H. Keller, F. Givel, M. Perroud and W. Wahli, Signaling cross-talk between peroxisome proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements, Mol Endocrinol 9 (1995), 794-804.
    • (1995) Mol Endocrinol , vol.9 , pp. 794-804
    • Keller, H.1    Givel, F.2    Perroud, M.3    Wahli, W.4
  • 119
    • 24344455975 scopus 로고    scopus 로고
    • Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor gamma signaling in breast cancer cells
    • D. Bonofiglio, S. Gabriele, S. Aquila et al., Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor gamma signaling in breast cancer cells. Clin Cancer Res 11 (2005). 6139-6147.
    • (2005) Clin Cancer Res , vol.11 , pp. 6139-6147
    • Bonofiglio, D.1    Gabriele, S.2    Aquila, S.3
  • 120
    • 18444412555 scopus 로고    scopus 로고
    • Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662
    • L.M. Leesnitzer, D.J. Parks, R.K. Bledsoc et al., Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662, Biochemistry 41 (2002), 6640-6650.
    • (2002) Biochemistry , vol.41 , pp. 6640-6650
    • Leesnitzer, L.M.1    Parks, D.J.2    Bledsoc, R.K.3
  • 121
    • 2442697906 scopus 로고    scopus 로고
    • The PAX8/PPARgamma fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARgamma inhibition
    • J. Gregory Powell, X. Wang, B.L. Allard et al., The PAX8/PPARgamma fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARgamma inhibition, Oncogene 23 (2004), 3634-3641.
    • (2004) Oncogene , vol.23 , pp. 3634-3641
    • Gregory Powell, J.1    Wang, X.2    Allard, B.L.3
  • 122
    • 19944362200 scopus 로고    scopus 로고
    • Small molecules and future regenerative medicine
    • S. Ding and PG. Schultz, Small molecules and future regenerative medicine, Curr Top Med Chem 5 (2005), 383-395.
    • (2005) Curr Top Med Chem , vol.5 , pp. 383-395
    • Ding, S.1    Schultz, P.G.2
  • 123
    • 4344619713 scopus 로고    scopus 로고
    • Pharmacological inhibitors of glycogen synthase kinase 3
    • L. Meijer, M. Flajolet and P. Greengard, Pharmacological inhibitors of glycogen synthase kinase 3, Trends Pharmacol Sci 25 (2004), 471-480.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 471-480
    • Meijer, L.1    Flajolet, M.2    Greengard, P.3
  • 124
    • 0037596751 scopus 로고    scopus 로고
    • Synthetic small molecules that control stem cell fate
    • S. Ding, T.Y. Wu, A. Brinker et al., Synthetic small molecules that control stem cell fate, Proc Natl. Acad Sci USA 100 (2003), 7632-7637.
    • (2003) Proc Natl. Acad Sci USA , vol.100 , pp. 7632-7637
    • Ding, S.1    Wu, T.Y.2    Brinker, A.3
  • 125
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • N. Sato, L. Meijer, L. Skaltsounis, P. Greengard and A.H. Brivardou, Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor, Nat Med 10 (2004), 55-63.
    • (2004) Nat Med , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivardou, A.H.5
  • 126
    • 30044444251 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation
    • J.J. Trowbridge, A. Xenocostas, R.T. Moon and M. Bhatia, Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation, Nat Med 12 (2006), 89-98.
    • (2006) Nat Med , vol.12 , pp. 89-98
    • Trowbridge, J.J.1    Xenocostas, A.2    Moon, R.T.3    Bhatia, M.4
  • 127
    • 33748850636 scopus 로고    scopus 로고
    • Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
    • P. Kirstetter, K. Anderson, B.T. Porse, S.E. Jacobsen and C. Nerlov, Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat Immunol 7 (2006), 1048-1056.
    • (2006) Nat Immunol , vol.7 , pp. 1048-1056
    • Kirstetter, P.1    Anderson, K.2    Porse, B.T.3    Jacobsen, S.E.4    Nerlov, C.5
  • 128
    • 33748859509 scopus 로고    scopus 로고
    • Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation
    • M. Scheller, J. Huelsken, F. Rosenbauer et al., Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation, Nat Immunol 7 (2006), 1037-1047.
    • (2006) Nat Immunol , vol.7 , pp. 1037-1047
    • Scheller, M.1    Huelsken, J.2    Rosenbauer, F.3
  • 129
    • 10444280878 scopus 로고    scopus 로고
    • Strategies to overcome resistance to targeted protein kinase inhibitors
    • H. Daub, K. Specht and A. Wrich, Strategies to overcome resistance to targeted protein kinase inhibitors, Nat Rev Drug Discov 3 (2004), 1001-1010.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 1001-1010
    • Daub, H.1    Specht, K.2    Wrich, A.3
  • 130
    • 0037466434 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitor STI-571/ Gleevee down-regulates the beta-catenin signaling activity
    • L. Zhou, N. An, R.C. Haydon et al., Tyrosine kinase inhibitor STI-571/ Gleevee down-regulates the beta-catenin signaling activity, Cancer Lett 193 (2003), 161-170.
    • (2003) Cancer Lett , vol.193 , pp. 161-170
    • Zhou, L.1    An, N.2    Haydon, R.C.3
  • 131
    • 1642512639 scopus 로고    scopus 로고
    • Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
    • M. Lepourcelet, Y.N. Chen, D.S. France et al., Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex, Cancer Cell 5 (2004), 91-102.
    • (2004) Cancer Cell , vol.5 , pp. 91-102
    • Lepourcelet, M.1    Chen, Y.N.2    France, D.S.3
  • 132
    • 33751239783 scopus 로고    scopus 로고
    • Self-renewal of embryonic stem cells by a small molecule
    • S. Chen, J.T. Do, Q. Zhang et al., Self-renewal of embryonic stem cells by a small molecule, Proc Natl Acad Sci USA 103 (2006), 17266-17271.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17266-17271
    • Chen, S.1    Do, J.T.2    Zhang, Q.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.