Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands

Development

Volumn 132, Issue 4, 2005, Pages 681-687

  Smith, Gilbert H ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Asymmetric division; Autoradiography; Mammary; Stem cell

Indexed keywords

BETA GALACTOSIDASE; BROXURIDINE; DNA; THYMIDINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREAST DEVELOPMENT; BREAST EPITHELIUM; CELL CYCLE; CELL DIVISION; CELL LABELING; CELL NUCLEUS; CONTROLLED STUDY; DNA STRAND; DNA SYNTHESIS; DNA TEMPLATE; EPITHELIUM CELL; FEMALE; MAMMARY GLAND; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGENY; STEM CELL; STROMA;

ANIMALS; AUTORADIOGRAPHY; BROMODEOXYURIDINE; CELL DIVISION; CELL NUCLEUS; DNA REPLICATION; EPITHELIAL CELLS; FEMALE; MAMMARY GLANDS, ANIMAL; MICE; MORPHOGENESIS; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; STEM CELLS; STROMAL CELLS; TEMPLATES, GENETIC;

ANIMALIA;

EID: 14844343185     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01609     Document Type: Article

References (20)

1. Berger, J. J. and Daniel, C. W. (1983). Stromal DNA synthesis is stimulated by young, but not serially, aged, mouse mammary epithelium. Mech. Ageing Dev. 23, 277-284.
2. Bickenbach, J. R. (1981). Identification and behavior of label-retaining cells in oral mucosa and skin. J. Dent. Res. 60, 1611-1620.
3. Boulanger, C. A., Wagner, K. U. and Smith, G. H. (2004). Parity-Induced mouse mammary cells are pluripotent, self-renewing and sensitive to TGF-β1 expression. Oncogene doi:10.1038/sj.onc.1208185
4. Cairns, J. (1975). Mutation selection and the natural history of cancer. Nature 255, 197-200.
5. Cairns, J. (2002). Somatic stem cells and the kinetics of mutagenesis and carcinogenesis. Proc. Natl. Acad. Sci. USA 99 10567-10570.
6. Cotsarelis, G., Sun, T. T. and Lavker, R. M. (1990). Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61, 1329-1337.
7. Daniel, C., DeOrne, K., Young, L., Blair, P. and Faulkin, L. (1968). The in vivo life span of normal and preneoplastic mouse mammary glands: a serial transplantation study. Proc. Natl. Acad. Sci. USA 61, 53-60.
8. Kordon, E. C. and Smith, G. H. (1998). An entire functional mammary gland may comprise the progeny from a single cell. Development 125, 1921-1930.
9. Lin, H. (2002). The stem-cell niche theory: lessons from flies. Nat. Rev. Genet. 3, 931-939.
10. Morris, R. J., Fischer, S. M. and Slaga, T. J. (1985). Evidence that the centrally and peripherally located cells in the murine epidermal proliferative unit are two distinct cell populations. J. Invest. Dermatol. 84, 277-281.
11. Potten, C. S., Hume, W. J., Reid, P. and Cairns, J. (1978). The segregation of DNA in epithelial stem cells. Cell 15 899-906.
12. Potten, C. S., Owen, G. and Booth, D. (2002). Intestinal stem cells protect their genome by selective segregation of template DNA strands. J. Cell Sci. 115, 2381-2388.
13. Smith, G. H. and Chepko, G. (2001). Mammary epithelial stem cells. Microsc. Res. Tech. 52, 190-203.
14. Soriano, P. (1999). Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70-71.
15. Wagner, K U., Boulanger, C. A., Henry, M. D., Sgagias, M., Hennighausen, L. and Smith, G. H. (2002). An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal. Development 129, 1377-1386.
16. Wagner, K. U., Wall, R. J., St-Onge, L., Gruss, P., Wynshaw-Boris, A., Garrett, L., Li, M., Furth, P. A. and Hennighausen, L. (1997). Cremediated gene deletion in the mammary gland. Nucleic Acids Res. 25, 4323-4330.
17. Welm, B. E., Tepera, S. B., Venezia, T., Graubert, T. A., Rosen, J. M. and Goodell, M. A. (2002). Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev. Biol. 245, 42-56.
18. Zeps, N., Dawkins, H. J., Papadimitriou, J. M., Redmond, S. L. and Walters, M. I. (1996). Detection of a population of long-lived cells in mammary epithelium of the mouse. Cell Tissue Res. 286, 525-536.
19. Zeps, N., Bentel, J. M., Papadimitriou, J. M., D'Antuono, M. F. and Dawkins, H. J. (1998). Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth. Differentiation 62, 221-226.
20. Zeps, N., Bentel, J. M., Papadimitriou, J. M. and Dawkins, H. J. (1999). Murine progesterone receptor expression in proliferating mammary epithelial cells during normal pubertal development and adult estrous cycle. Association with eralpha and erbeta status. J. Histochem. Cytochem. 47, 1323-1330.