An adjunct mammary epithelial cell population in parous females: Its role in functional adaptation and tissue renewal

Development

Volumn 129, Issue 6, 2002, Pages 1377-1386

  Wagner, Kay Uwe ^a   Boulanger, Corinne A ^a   Henry, MaLinda D ^a   Sgagias, Magdalene ^a   Hennighausen, Lothar ^a   Smith, Gilbert H ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Cre recombinase; Differentiation; Epithelium; Involution; Mammary gland; Mouse; Parity; Stem cells

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREAST EPITHELIUM; CELL DEATH; CELL DIFFERENTIATION; CELL FUNCTION; CELL POPULATION; CELL RENEWAL; CELL TRANSPLANTATION; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; GENETIC ENGINEERING; INVOLUTION; LACTATION; MORPHOGENESIS; MORPHOLOGICAL ADAPTATION; MOUSE; MULTIPARA; NONHUMAN; NULLIPARA; PHENOTYPE; PREGNANCY; PRIORITY JOURNAL; SECRETORY CELL; STEM CELL;

ADAPTATION, BIOLOGICAL; ANIMALS; CELL DEATH; CELL DIFFERENTIATION; EPITHELIAL CELLS; FEMALE; INTEGRASES; MAMMARY GLANDS, ANIMAL; MICE; MICE, TRANSGENIC; MILK PROTEINS; PARITY; PREGNANCY; STEM CELLS; VIRAL PROTEINS;

ANIMALIA;

EID: 0036339643     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Expression of a whey acidic protein transgene during mammary development. Evidence for different mechanisms of regulation during pregnancy and lactation
2. A novel regulatory mechanism for whey acidic protein gene expression
3. The in vivo life span of normal and preneoplastic mouse mammary glands: A serial transplantation study
4. The influence of mammogenic hormones on serially transplanted mouse mammary gland
5. Loss of heterozygosity in normal tissue adjacent to breast carcinomas
6. Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice
7. Regulation of growth and spacing of gland elements in the mammary fat pad of the C3H mouse
8. Think globally, act locally: The making of a mouse mammary gland
9. Signaling pathways in the mammary gland development
10. Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene
11. Quantitative studies of ductal versus alveolar differentiation from rat mammary clonogens
12. An entire functional mammary gland may comprise the progeny from a single cell
13. Genetic alterations in 'normal' luminal and myoepithelial cells of the breast
14. Transfection of primary mammary epithelial cells by viral and nonviral methods
15. SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice
16. Stat5a is mandatory for adult mammary gland development and lactogenesis
17. Functional release of Stat5a-null mammary tissue through the activation of compensating signals including Stat5b
18. Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice
19. Two distinct phases of apoptosis in mammary gland involution: Proteinase-independent and -dependent pathways
20. Lactation and cancer of the breast. A summary of an international study
21. Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice
22. Chemical carcinogen-induced tumorigenesis in parous, involuted mouse mammary glands
23. Establishment of mouse mammary cell lines
24. Signal Transducer and Activator Transcription 5 (Stat5) controls the proliferation and differentiation of mammary alveolar epithelium
25. Physiology of lactation
26. Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse
27. Comparison of the regulation of the whey acidic protein gene with that of a hybrid gene containing the whey acidic protein gene promoter in transgenic mice
28. Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation
29. Rescue of mammary epithelium of early lethal phenotypes by embryonic mammary gland transplantation as exemplified with insulin receptor null mice
30. Functional mammary gland development and tumor formation are not affected by the absence of the retinoblastoma gene
31. Microsatellite alterations indicating monoclonality in atypical hyperplasias associated with breast cancer
32. Mammary gland neoplasia in long-term rodent studies
33. Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats
34. p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis
35. Differentiation of separated mouse mammary luminal epithelial and myoepithelial cells cultured on EHS matrix analyzed by indirect immunofluorescence of cytoskeletal antigens
36. Functional differentiation of virgin mouse mammary epithelium in explant culture is dependent upon extracellular proline
37. Experimental mammary epithelial morphogenesis in an in vivo model: Evidence for distinct cellular progenitors of the ductal and lobular phenotype
38. Functional differentiation in mouse mammary gland epithelium is attained through DNA synthesis, inconsequent of mitosis
39. Mammary epithelial stem cells
40. Evidence of separate pathways for viral and chemical carcinogenesis in C3H/StWi mouse mammary glands
41. Long-term in vivo expression of genes introduced by retrovirus-mediated transfer into mammary epithelial cells
42. Generalized lacZ expression with the ROSA26 Cre reporter strain
43. Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast
44. Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
45. Functional interactions between Stat5 and the glucocorticoid receptor
46. Multiple hormone interactions in the developmental biology of the mammary gland
47. Contiguous patches of normal human mammary epithelium derived from a single stem cell: Implications for breast carcinogenesis
48. Difference between mammary epithelial cells from mature virgin and primiparous mice
49. Dissociation of cytological and functional differential in virgin mouse mammary gland during inhibition of DNA synthesis
50. Cre-mediated gene deletion in the mammary gland
51. Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: A review and tribute to Charles Brenton Huggins
52. Cooperative effects of STAT5 (signal transducer and activator of transcription 5) and C/EBPbeta (CCAAT/enhancer-binding protein-beta) on beta-casein gene transcription are mediated by the glucocorticoid receptor
53. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
54. The influence of host and tissue age on life span and growth rate of serially transplanted mouse mammary gland