Modulation of Sirt1 by resveratrol and nicotinamide alters proliferation and differentiation of pig preadipocytes

Molecular and Cellular Biochemistry

Volumn 307, Issue 1-2, 2008, Pages 129-140

  Bai, Liang ^a   Pang, Wei Jun ^a   Yang, Yan Jun ^a   Yang, Gong She ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Adipocyte genes; Differentiation; FoxO1; Pig; Preadipocyte; Proliferation; Sirt1

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; MESSENGER RNA; NICOTINAMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; RESVERATROL; SIRTUIN; SIRTUIN 1; TRANSCRIPTION FACTOR FKHR;

ADIPOCYTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SPECIFICITY; CELL STIMULATION; CONTROLLED STUDY; CULTURE MEDIUM; DEVELOPMENTAL STAGE; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC ANALYSIS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY; MITOSIS INHIBITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROADIPOCYTE; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; SWINE; TISSUE DISTRIBUTION;

ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; NIACINAMIDE; RNA, MESSENGER; SIRTUINS; STILBENES; SWINE; TIME FACTORS;

BOVINAE; SUIDAE;

EID: 36949021068     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9592-5     Document Type: Article

References (52)

1. Morrison RF, Farmer SR (2000) Hormonal signaling and transcriptional control of adipocyte differentiation. J Nutr 130:3116S-3121S
2. Gregoire FM (2001) Adipocyte differentiation: From fibroblast to endocrine cell. Exp Biol Med 226:997-1002
3. Fe've B (2005) Adipogenesis: Cellular and molecular aspects. Best Pract Res Clin Endocrinol Metab 19:483-499
4. Imai SI, Armstrong CM, Kaeberlein M et al (2000) Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403:795-800
5. Smith JS, Brachmann CB, Celic I et al (2000) A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2. Proc Natl Acad Sci USA 97:6658-6663
6. Frye RA (1999) Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-Ribosyltransferase activity. Biochem Biophys Res Commun 260:273-279
7. Frye RA (2000) Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 273:793-798
8. Sherman JM, Stone EM, Freeman-Cook LL et al (1999) The conserved core of a human SIR2 homologue functions in yeast silencing. Mol Biol Cell 10:3045-3059
9. Motta MC, Divecha N, Lemieux M et al (2004) Mammalian SIRT1 represses Forkhead transcription factors. Cell 116:551-563
10. Brunet A, Sweeney LB, Sturgill JF et al (2004) Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303:2011-2015
11. Fulco M, Schiltz RL, Iezzi S et al (2003) Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol Cell 12:51-62
12. Luo J, Nikolaev AY, Imai S et al (2001) Negative control of p53 by Sir2α promotes cell survival under stress. Cell 107:137-148
13. Vaziri H, Dessain SK, Eaton EN et al (2001) hSIR2 SIRT1 functions as an NAD-dependent p53 deacetylase. Cell 107:149-159
14. Rodgers JT, Lerin C, Haas W et al (2005) Nutrient control of glucose homeostasis through a complex of PGC-1a and SIRT1. Nature 434:113-118
15. McBurney MW, Yang XF, Jardine K et al (2003) The mammalian SIR2α protein has a role in embryogenesis and gametogenesis. Mol Cell Biol 23:38-54
16. Picard F, Kurtev M, Chung NJ et al (2004) Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ. Nature 429:771-776
17. Bäckesjö CM, Li Y, Lindgren U et al (2006) Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells. J Bone Miner Res 21:993-1002
18. Picard F, Guarente L (2005) Molecular links between aging and adipose tissue. Int J Obesity 29: S36-S39
19. Bordone L, Motta MC, Picard F et al (2006) Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells. PLoS Biol 4:210-220
20. Lagouge M, Argmann C, Gerhart-Hines Z et al (2006) Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell 127:1109-1122
21. Baur JA, Pearson KJ, Price NL et al (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444:337-342
22. Gianfranco B, Alfredo C (2004) Metabolic and cardiovascular disorders in highly inbred lines for intensive pig farming: How animal welfare evaluation could improve the basic knowledge of human obesity. Ann 1st Super Sanita 40:241-244
23. Belliger DA, Merrichks EP, Nichols TC (2006) Swine models of type 2 diabetes mellitus: Insulin resistance, glucose tolerance, and cardiovascular complications. ILAR J 47:243-258
24. Larsen MO, Rolin B (2004) Use of the Göttingen minipig as a model of diabetes, with special focus on type 1 diabetes research. ILAR J 45:303-313
25. Fernandez ML (2001) Guinea pigs as models for cholesterol and lipoprotein metabolism. J Nutr 131:10-20
26. Vodicka P, Smetana K, Dvoránková B et al (2005) The miniature pig as an animal model in biomedical research. N Y Acad Sci 1049:161-171
27. Howitz KT, Bitterman KJ, Cohen HY et al (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425:191-196
28. Buck SW, Gallo CM, Smith JS (2004) Diversity in the Sir2 family of protein deacetylases. J Leukocyte Biol 75:939-950
29. Brunet A, Bonni A, Zigmond MJ et al (1999) Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96:857-868
30. Kops GJ, Ruiter ND, Vries-Smits AM et al (1999) Direct control of the Forkhead transcription factor AFX by protein kinase B. Nature 398:630-634
31. Jacobs FMJ, Heide LP, Wijchers PJEC et al (2003) FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics. J Biol Chem 278:35959-35967
32. Nakae J, Biggs WH, Kitamura T et al (2002) Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding Forkhead transcription factor foxo1. Nat Genet 32:245-253
33. Altomonte J, Cong L, Harbaran S et al (2004) Foxo1 mediates insulin action on apoC-III and triglyceride metabolism. J Clin Invest 114:1493-1503
34. Zhang WW, Patil S, Chauhan B et al (2006) FoxO1 regulates multiple metabolic pathways in the liver. J Biol Chem 281:10105-10117
35. Nakae J, Kitamura T, Kitamura Y et al (2003) The Forkhead transcription factor foxo1 regulates adipocyte differentiation. Dev Cell 4:119-129
36. Cohen HY, Miller C, Bitterman KJ et al (2004) Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305:390-392
37. Michishita E, Park JY, Burneskis JM et al (2005) Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 16:4623-4635
38. Fang JG, Lu M, Chen ZH et al (2002) Antioxidant effects of resveratrol and its analogues against the free-radical-induced peroxidation of linoleic acid in micelles. Chemistry 8:4191-4198
39. Ray PS, Maulik G, Cordis GA et al (1999) The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury. Free Radic Biol Med 27:160-169
40. Araki T, Sasaki Y, Milbrandt J (2004) Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305:1010-1013
41. Yeung F, Hoberg JE, Ramsey CS et al (2004) Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 23:2369-2380
42. Dietrich L S (1971) Regulation of nicotinamide metabolism. Am J Clin Nutr 24:800-804
43. Bitterman KJ, Anderson RM, Cohen HY et al (2002) Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1. J Biol Chem 277:45099-45107
44. Kaanders JH, Pop LA, Marres HA et al (2002) ARCON: Experience in 215 patients with advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 52:769-778
45. Otonkoski T, Beattie GM, Mally MI et al (1993) Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells. J Clin Invest 92:1459-1466
46. Vaca P, Berna G, Martín F et al (2003) Nicotinamide induces both proliferation and differentiation of embryonic stem cells into insulin-producing cells. Transplant Proc 35:2021-2023
47. Gregoire FM, Smas CM, Sul HS (1998) Understanding adipocyte differentiation. Physiol Rev 78:783-809
48. Giannakou M E, Partridge L (2004) The interaction between FOXO and SIRT1: Tipping the balance towards survival. TRENDS Cell Biol 14:408-412
49. Armoni M, Harel C, Karni S et al (2006) FOXO1 represses peroxisome proliferator-activated receptor-γ1 and -γ2 gene promoters in primary adipocytes: A novel paradigm to increase insulin sensitivity. J Biol Chem 281:19881-19891
50. Gan LX, Han YS, Bastianett S et al (2005) FoxO-dependent and - independent mechanisms mediate SirT1 effects on IGFBP-1 gene expression. Biochem Biophys Res Commun 337:1092-1096
51. Lemieux ME, Yang X, Jardine K et al (2005) The Sirt1 deacetylase modulates the insulin-like growth factor signaling pathway in mammals. Mech Ageing Dev 126:1097-1105
52. Han MK, Mantel C, Guo Y et al (2005) Role of SIRT1 in proliferation and self-renewal of mouse embryonic stem cells. Proc Soc Exper Biol Med 106:520