Mental retardation in Down syndrome: From gene dosage imbalance to molecular and cellular mechanisms

Neuroscience Research

Volumn 59, Issue 4, 2007, Pages 349-369

  Rachidi, Mohammed ^a   Lopes, Carmela ^a,b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b UNIVERSITÉ DE LA POLYNÉSIE FRANÇAISE   (French Polynesia)

Author keywords

Down syndrome; Gene dosage imbalance; Gene expression variation; Learning and memory; Mental retardation; Molecular mechanism model; Neurological disorders; Transcriptome

Indexed keywords

CHROMOSOME 21; COGNITIVE DEFECT; DOWN SYNDROME; GENE DOSAGE; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; MENTAL DEFICIENCY; NERVE CELL DIFFERENTIATION; NEUROLOGIC DISEASE; NEUROPATHOLOGY; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; TRANSGENIC MOUSE; TRISOMY 21;

ANIMALS; BRAIN CHEMISTRY; CHROMOSOMES, HUMAN, PAIR 21; DISEASE MODELS, ANIMAL; DOWN SYNDROME; GENE DOSAGE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MENTAL RETARDATION; MICE; REGULATORY ELEMENTS, TRANSCRIPTIONAL;

EID: 35548991458     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2007.08.007     Document Type: Review

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