Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome

Molecular and Cellular Neurosciences

Volumn 7, Issue 1, 1996, Pages 1-16

  Fan, Chen Ming ^a,f   Kuwana, Ellen ^a,b   Bulfone, Alessandro ^b   Fletcher, Colin F ^c   Copeland, Neal G ^c   Jenkins, Nancy A ^c   Crews, Stephen ^d   Martinez, Salvador ^e   Puelles, Luis ^e   Rubenstein, John L R ^b   Tessier Lavigne, Marc ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MURCIA   (Spain)

^f GEOPHYSICAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BRAIN DEVELOPMENT; CHROMOSOME 21; DOWN SYNDROME; DROSOPHILA; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENE LOCATION; GENE SEQUENCE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

MURINAE;

EID: 0029968399     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1996.0001     Document Type: Article

References (56)

1. Bae, S.-C., Ogawa, E., Maruyama, M., Oka, H., Satake, M., Shigesada, K., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., and Ito, Y. (1994). PEBP2aB/mouse AML1 consists of multiple isoforms that possess differential transactivation potential. Mol. Cell. Biol. 14: 3242-3252.
2. Bulfone, A. P., Puelles, L., Porteus, M. H., Frohman, M. A., Martin, G. R., and Rubenstein, J. L. (1993). Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J. Neurosci. 13: 3155-3172.
3. Burbach, K. M., Poland, A., and Bradfield, C. A. (1992). Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor. Proc. Natl. Acad. Sci. USA 89: 8185-8189.
4. Chen, H., Chrast, R., Rossier, C., Gos, A., Antonarakis, S. E., Kudoh, J., Yamaki, A., Shindoh, N., Maeda, H., Minoshima, S., and Shimizu, N. (1995). Single-minded and Down syndrome. Nature Genet. 10: 9-10.
5. Chevallier, A., Kieny, M., and Mauger, A. (1977). Limb-somite relationship: Origin of the limb musculature. J. Embryol. Exp. Morph. 41: 245-258.
6. Chomczynski, P., and Sacchi, N. (1987). Single-step method of RNA isolation by acid gaunidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159.
7. Christ, B., Jacob, H. J., and Jacob, M. (1977). Experimental analysis of the origin of the wing musculature in avian embryos. Anat. Embryol. 150: 171-186.
8. Copeland, N. G., and Jenkins, N. A. (1991). Development and application of a molecular genetic linkage map of the mouse genome. Trends Genet. 7: 113-118.
9. Crews, S., Franks, R., Hu, S., Matthews, B., and Nambu, J. (1992). Drosophila single-minded gene and the molecular genetics of CNS midline development. J. Exp. Zool. 261: 234-244.
10. Crews, S., Thomas, J., and Goodman, C. (1988). The Drosophila single-minded gene encodes a nuclear protein with sequence similarity to the per gene product. Cell 52: 143-151.
11. Dahmane, N., Charron, G., Lopes, C., Yaspo, M.-L., Maunoury, C., Decorte, L., Sinet, P.-M., Bloch, B., and Delabar, J-M. (1995). Down syndrome critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system dvelopment. Proc. Natl. Acad. Sci. USA 92: 9191-9195.
12. Davis, C. A., and Joyner, A. L. (1988). Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development. Genes Dev. 2: 1736-1744.
13. Delabar, J. M., Theophile, D., Rahmani, Z., Chettouch, Z., Blouin, J. L., Prieur, M., Noel, B., and Sinet, P. M. (1993). Molecular mapping of twenty-four features of Down syndrome on chromosome 21. Eur. J. Human Genet. 1: 114-124.
14. Figdor, M. C., and Stern, C. D. (1993). Segmental organization of embryonic diencephalon. Nature 363: 630-634.
15. Franks, R. G., and Crews, S. T. (1994). Transcriptional activation domains of the single-minded bHLH protein are required for CNS midline cell development. Mech. Dev. 45: 269-277.
16. Frohman, M. A., Boyle, M., and Martin, G. R. (1990). Isolation of the mouse Hox-2.9 gene: Analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm. Development 110: 589-607.
17. Green, E. L. (1981). Linkage, recombination, and mapping. In Genetics and Probability in Animal Breeding Experiments (E. L. Green, Ed.), pp. 77-83. Oxford Univ. Press, New York.
18. Green, M. C. (1989). Catalog of mutant genes and polymorphic loci. In Genetic Variants and Strains of the Laboratory Mouse (M. C. Green, Ed.), pp. 12-403. Oxford Univ. Press, New York.
19. Habets, G. G., van der Kammen, R. A., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Hagemeijer, A., and Collard, J. G. (1995). The invasion-inducing TIAM-1 gene maps to human chromosome 21q22 and mouse chromosome 16. Cytogenet. Cell Genet. 70: 48-51.
20. Haefliger, J.-A., Bruzzone, R., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., and Paul, D. L. (1992). Four novel members of the connexin family of gap junction proteins: Molecular cloning, expression and chromosome mapping. J. Biol. Chem. 267: 2057-2064.
21. Heyman, S., Kent, A., and Lumsden, A. (1993). Cellular morphology and extracellular space at rhombomere boundaries in the chick embryo hindbrain. Dev. Dynamics 198: 241-253.
22. Hoffman, E. C., Reyes, H., Chu, F. F., Sander, F., Conley, L. H., Brooks, B. A., and Hankinson, O. (1991). Cloning of a factor required for activity of the Ah (dioxin) receptor. Science 252: 954-958.
23. Huang, Z. J., Edery, I., and Rosbash, M. (1993). PAS is a dimerization domain common to Drosophila period and several transcription factors. Nature 364: 259-262.
24. Jain, S., Dolwick, K. M., Schmidt, J. V., and Bradfield, C. A. (1994). Potent transcription activation domains of the Ah receptor and the Ah receptor nuclear translocaror map to their carboxyl termini. J. Biol. Chem. 269: 31518-31524.
25. Jan, Y. N., and Jan, L. Y. (1993). HLH proteins, fly neurogenesis, and vertebrate myogenesis. Cell 75: 827-830.
26. Jenkins, N. A., Copeland, N. G., Taylor, B. A., and Lee, B. K. (1982). Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. J. Virol. 43: 26-36.
27. Justice, M. J., Siracusa, L. D., Gilbert, D. J., Heisterkamp, N., Groffen, J., Chada, K., Silan, C. M., Copeland, N. G., and Jenkins, N. A. (1990). A genetic linkage map of mouse chromosome 10: Localization of 18 molecular markers using a single interspecific backcross. Genetics 125: 855-866.
28. Klar, A., Baldassare, M., and Jessell, T. M. (1992). F-spondin: A gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension. Cell 69: 95-110.
29. Lewis, J. O., and Crews, S. T. (1994). Genetic analysis of the Drosophila single-minded gene reveals a central nervous system influence on muscle development. Mech. Dev. 48: 81-91.
30. Lindebro, M. C., Poellinger, L., and Whitelaw, M. L. (1995). Protein-protein interaction via PAS domains: Role of the PAS domain in positive and negative regulation of the bHLH/PAS dioxin receptor-Arnt transcription factor complex. EMBO J. 14: 3528-3539.
31. Maisonpierre, P., Belluscio, L., Squinto, S., Ip, N., Furth, M., Lindsay, R., and Yancopoulos, G. (1989). Neurotrophin-3: A neurotrophic factor related to NGF and BDNF. Science 247: 1446-1451.
32. McMahon, A. P., Joyner, A. L., Bradley, A., and McMahon, J. A. (1992). The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1-mice results from stepwise deletion of engrailed-expressing cells by 9.5 days post-coitum. Cell 69: 581-595.
33. Muenke, M., Bone, L., Mitchell, H., Hart, I., Walton, K., Hall-Johnson, K., Ippel, E., Dietz-Band, J., Karloy, K., Fan, C.-M., Tessier-Lavigne, M., and Patterson, D. (1995). Physical mapping of the holoprosencephaly critical region in 21q22.3, exclusion of SIM2 as a candidate gene for HPE, and mapping the SIM2 to a region of chromosome 21 important for Down syndrome. Am. J. Human Genet. 57: 1074-1079.
34. Nambu, J. R., Lewis, J. O., Wharton, K. J., and Crews, S. T. (1991). The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development. Cell 67: 1157-1167.
35. Olson, E. N., and Klein, W. H. (1994). bHLH factors in muscle development: Dead lines and commitments, what to leave in and what to leave out. Genes Dev. 8: 1-8.
36. Ott, M.-O., Bober, E., Lyons, G., Arnold, H., and Buckingham, M. (1991). Early expression of the myogenic regulatory gene, Myf5, in precursor cells of skeletal muscle in the mouse embryo. Development 111: 1097-1107.
37. Porteus, M. H., Bulfone, A., Ciaranello, R. D., and Rubenstein, J. L. R. (1991). Isolation and Characterization of a Novel cDNA Encoding a Homeodomain that is Developmentally Regulated in the Ventral Forebrain. Neuron 7: 221-229.
38. Porteus, M. H., Bulfone, A., Liu, J. K., Puelles, L., Lo, L. C., and Rubenstein, J. L. R. (1994). DLX-2, MASH-1, MAP-2 expression and bromodeoxyuridine incorporation define molecularly distinct cell populations in the embryonic mouse forebrain. J. Neurosci. 14: 6370-6383.
39. Puelles, L., and Rubenstein, J. L. R. (1993). Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization. Trends Neurosci. 16: 472-479.
40. Rao, V. N., Papas, T. S., and Reddy, E. S. (1987). erg, a human ets-related gene on chromosome 21: Alternative splicing, polyadenylation, and translation. Science 237: 635-639.
41. Reisz-Porszasz, S., Probst, M. R., Fukunaga, B. N., and Hankinson, O. (1994). Identification of functional domains of the arcryl hydrocarbon receptor nuclear translocator protein (ARNT). Mol. Cell. Biol. 14: 6075-6086.
42. Robinson, G. W., Wray, S., and Mahon, K. A. (1991). Spatially restricted expression of a member of a new family of murine Distal-less homeobox genes in the developing forebrain. New Biol. 3: 1183-1194.
43. Rubenstein, J. L., Martinez, S., Shimamura, K., and Puelles, L. (1994). The embryonic vertebrate forebrain: The prosomeric model. Science 266: 578-580.
44. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Mannual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
45. Sanger, F., Nicklen, S., and Coulson, A. R. (1977). DNA sequencing with chain-termination inhibitors. Proc. Natl. Acad. Sci. USA 74: 5463-5468.
46. Schaeren-Wiemers, N., and Gerfin-Moser, A. (1993). A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes. Histochemistry 100: 431-440.
47. Shimamura, K., Hartigan, D. J., Matinez, S., Puelles, L., and Rubenstein, J. L. R. (1995). Longitudinal organization of the anterior neural plate and neural tube. Development, 121: 3923-3933.
48. 2 tension. Proc. Natl. Acad. Sci. USA 92: 5510-5514.
49. Weintraub, H., Davis, R., Tapscott, S., Thayer, M., Krause, M., Benezra, R., Blackwell, T. K., Turner, D., Rupp, R., Hollenberg, S., Zhuang, Y., and Lassar, A. (1991). The myoD gene family: Nodal point during specification of the muscle cell lineage. Science 248: 761-765.
50. Whitelaw, M., Pongratz, I., Wilhelmsson, A., Gustafsson, J. A., and Poellinger, L. (1993). Ligand-dependent recruitment of the Arnt coregulator determines DNA recognition by the dioxin receptor. Mol. Cell. Biol. 13: 2504-2514.
51. Whitelaw, M. L., Gottlicher, M., Gustafsson, J.-A., and Poellinger, L. (1993). Definition of a novel ligand binding domain of a nuclear bHLH receptor: Co-localization of ligand and HSP90 binding activities within the regulable inactivation domain of the dioxin receptor. EMBO J. 12: 4169-4179.
52. Wilhelmsson, A., Cuthill, S., Denis, M., Wikstrom, A. C., Gustafsson, J. A., and Poellinger, L. (1990). The specific DNA binding activity of the dioxin receptor is modulated by the 90 kd heat shock protein. EMBO J. 9: 69-76.
53. Wilkison, D. G., and Nieto, M. (1993). Detection of mesenger RNA by in situ hybrydization to tissue sections and whole mounts. Methods Enzymol. 225: 361-373.
54. Wolf, C., Thisse, C., Stoetzel, C., Thisse, B., Gerlinger, P., and Perrin-Schmitt, F. (1991). The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes. Dev. Biol. 143: 363-373.
55. Yaginuma, H., Shiga, T., Homma, S., Ishihara, R., and Oppenheim, R. W. (1990). Identification of early developing axon projections from spinal interneurons in the chick embryo with a neuron specific β-tubulin antibody: Evidence for a new "pioneer" pathway in the spinal cord. Development 108: 705-716.
56. Yamada, T., Placzek, M., Tanaka, H., Dodd, J., and Jessell, T. M. (1991). Control of cell pattern in the developing nervous system: polarizing activity of the floor plate and notochord. Cell 64: 635-647.