Learning and memory in S100-β transgenic mice: An analysis of impaired and preserved function

Neurobiology of Learning and Memory

Volumn 75, Issue 2, 2001, Pages 230-243

  Winocur, Gordon ^a   Roder, John ^b   Lobaugh, Nancy ^a  

^a ROTMAN RESEARCH INSTITUTE   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Learning and memory; S100 ; Transgenic mice

Indexed keywords

PROTEIN S100B;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; HIPPOCAMPUS; LEARNING; MALE; MEMORY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SPATIAL DISCRIMINATION; SPATIAL MEMORY; TRANSGENIC MOUSE;

EID: 0035704553     PISSN: 10747427     EISSN: None     Source Type: Journal    
DOI: 10.1006/nlme.2000.3961     Document Type: Article

References (44)

1. Spatial recognition and spatial order memory in patients with dementia of the Alzheimer's type
2. The effects of hippocampal lesions upon spatial and non-spatial tests of working memory
3. S100 beta stimulates calcium fluxes in glial and neuronal cells
4. A synaptic model of memory: Long-term potentiation in the hippocampus
5. Cognitive impairment in adults with Down's syndrome: Similarities to early cognitive changes in Alzheimer's disease
6. Electrophysiological markers of aging and memory loss in rats
7. Effortful and automatic processes associated with Down syndrome and nonspecific mental retardation
8. Cell-specific expression of high levels of human S 100 beta in transgenic mouse brain is dependent on gene dosage
9. A comparison of old and young rats' performance on a test of nonmatching-to-sample: An analysis of age-related encoding and memory deficits
10. Transfer of information concerning distant foods: A laboratory investigation of the 'information-centre' hypothesis
11. Female transgenic mice carrying the human gene for S 100-β are hyperactive
12. T-Maze spontaneous alteration rate is decreased in S 100-β transgenic mice
13. Overexpression of a calcium-binding protein, S100β in astrocytes alters synaptic plasticity and impairs spatial learning in transgenic mice
14. Learning and memory impairment in rats fed a high saturated fat diet
15. Brain interleukin 1 and S100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
16. Primate learning tasks reveal strong impairments in patients with presenile or senile dementia of the Alzheimer type
17. Spatial exploration in transgenic mice expressing human β-S100
18. Memory for spatial locations, motor responses, and objects: Triple dissociation among the hippocampus, caudate nucleus, and extrastriate visual cortex
19. Animal models for human PFC- related disorders
20. Parallel information processing in the water maze: Evidence for independent memory systems involving dorsal striatum and hippocampus
21. Amnesia following operation on the temporal lobes
22. Place navigation impaired in rats with hippocampal lesions
23. Learning, memory and neural function in Down's syndrome
24. Hippocampus, space, and memory
25. Remembrance of places past: Spatial memory in rats
26. The caudate nucleus and acquisition of win-shift radial-maze behavior: Effect of exposure to the reinforcer during maze adaptation
27. Frontal lobes and working memory: Evidence from investigations of the effects of cortical excisions in non-human primates
28. Relationship of Down's syndrome to Alzheimer's disease
29. Associations across time: The hippocampus as a temporary memory store
30. Critical determinants of nonspatial working memory deficits in rats with conventional lesions of the hippocampus or fornix
31. Memory and the effect of cold shock in the water maze in S100-β transgenic mice
32. A comparative study of visuospatial memory and learning in Alzheimer-type dementia and Parkinson's disease
33. The effects of fornix and medial prefrontal lesions on delayed nonmatching-to-sample by rats
34. Memory and the hippocampal region: A synthesis of findings with rats, monkeys, and humans
35. Dorsal medial thalamic lesions impair radial arm maze performance in the rat
36. Comparison between the effects of ethanol and diazepam on spatial working memory in the rat
37. Radial-arm-maze behavior by rats with dorsal hippocampal lesions: Effects of cuing
38. The hippocampus and thalamus: Their roles in short- and long-term memory and the effects of interference
39. Anterograde and retrograde amnesia in rats with dorsal hippocampal or dorsomedial thalamic lesions
40. Functional dissociation of the hippocampus and prefrontal cortex in learning and memory
41. A comparison of normal old rats and young adult rats with lesions to the hippocampus or prefrontal cortex on a test of matching-to-sample
42. Conditional learning in aged rats: Evidence of hippocampal and prefrontal cortex impairment
43. Prefrontal cortex and caudate nucleus in conditional associative learning: Dissociated effects of selective brain lesions in rats
44. Anterograde and retrograde amnesia following lesions to frontal cortex in rats