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Volumn 21, Issue 20, 2007, Pages 2511-2524

Regulation of vascular morphogenesis by Notch signaling

Author keywords

Angiogenesis; Dll4; Endothelial cell; Notch; Sprouting

Indexed keywords

DELTA LIKE 4 PROTEIN; JAGGED1; NOTCH RECEPTOR; NOTCH3 RECEPTOR; PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN A;

EID: 35349012675     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1589207     Document Type: Review
Times cited : (382)

References (118)
  • 1
    • 34249689753 scopus 로고    scopus 로고
    • Molecular regulation of angiogenesis and lymphangiogenesis
    • Adams, R.H. and Alitalo, K. 2007. Molecular regulation of angiogenesis and lymphangiogenesis. Nat. Rev. Mol. Cell Biol. 8: 464-478.
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 464-478
    • Adams, R.H.1    Alitalo, K.2
  • 2
    • 2342496710 scopus 로고    scopus 로고
    • Instruction of distinct CD4 T helper cell fates by different Notch ligands on antigen-presenting cells
    • Amsen, D., Blander, J.M., Lee, G.R., Tanigaki, K., Honjo, T., and Flavell, R.A. 2004. Instruction of distinct CD4 T helper cell fates by different Notch ligands on antigen-presenting cells. Cell 117: 515-526.
    • (2004) Cell , vol.117 , pp. 515-526
    • Amsen, D.1    Blander, J.M.2    Lee, G.R.3    Tanigaki, K.4    Honjo, T.5    Flavell, R.A.6
  • 3
    • 0032807866 scopus 로고    scopus 로고
    • Expression of the mouse Delta1 gene during organogenesis and fetal development
    • Beckers, J., Clark, A., Wunsch, K., Hrabe De Angelis, M., and Gossler, A. 1999. Expression of the mouse Delta1 gene during organogenesis and fetal development. Mech. Dev. 84: 165-168.
    • (1999) Mech. Dev , vol.84 , pp. 165-168
    • Beckers, J.1    Clark, A.2    Wunsch, K.3    Hrabe De Angelis, M.4    Gossler, A.5
  • 4
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • Bray, S.J. 2006. Notch signalling: A simple pathway becomes complex. Nat. Rev. Mol. Cell Biol. 7: 678-689.
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 6
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • Carmeliet, P. 2003. Angiogenesis in health and disease. Nat. Med. 9: 653-660.
    • (2003) Nat. Med , vol.9 , pp. 653-660
    • Carmeliet, P.1
  • 7
    • 0029089247 scopus 로고
    • Clinical spectrum of CADASIL: A study of 7 families. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
    • Chabriat, H., Vahedi, K., Iba-Zizen, M.T., Joutel, A., Nibbio, A., Nagy, T.G., Krebs, M.O., Julien, J., Dubois, B., Ducrocq, X., et al. 1995. Clinical spectrum of CADASIL: A study of 7 families. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Lancet 346: 934-939.
    • (1995) Lancet , vol.346 , pp. 934-939
    • Chabriat, H.1    Vahedi, K.2    Iba-Zizen, M.T.3    Joutel, A.4    Nibbio, A.5    Nagy, T.G.6    Krebs, M.O.7    Julien, J.8    Dubois, B.9    Ducrocq, X.10
  • 8
    • 33645465011 scopus 로고    scopus 로고
    • Why is Delta endocytosis required for effective activation of Notch?
    • Chitnis, A. 2006. Why is Delta endocytosis required for effective activation of Notch? Dev. Dyn. 235: 886-894.
    • (2006) Dev. Dyn , vol.235 , pp. 886-894
    • Chitnis, A.1
  • 9
    • 8844262579 scopus 로고    scopus 로고
    • Periodic Delta-like 4 expression in developing retinal arteries
    • Claxton, S. and Fruttiger, M. 2004. Periodic Delta-like 4 expression in developing retinal arteries. Brain Res. Gene Expr. Patterns 5: 123-127.
    • (2004) Brain Res. Gene Expr. Patterns , vol.5 , pp. 123-127
    • Claxton, S.1    Fruttiger, M.2
  • 10
    • 22344436360 scopus 로고    scopus 로고
    • p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
    • Devgan, V., Mammucari, C., Millar, S.E., Brisken, C., and Dotto, G.P. 2005. p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes & Dev. 19: 1485-1495.
    • (2005) Genes & Dev , vol.19 , pp. 1485-1495
    • Devgan, V.1    Mammucari, C.2    Millar, S.E.3    Brisken, C.4    Dotto, G.P.5
  • 11
    • 33845642740 scopus 로고    scopus 로고
    • Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate
    • Diez, H., Fischer, A., Winkler, A., Hu, C.J., Hatzopoulos, A.K., Breier, G., and Gessler, M. 2007. Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate. Exp. Cell Res. 313: 1-9.
    • (2007) Exp. Cell Res , vol.313 , pp. 1-9
    • Diez, H.1    Fischer, A.2    Winkler, A.3    Hu, C.J.4    Hatzopoulos, A.K.5    Breier, G.6    Gessler, M.7
  • 13
    • 33646869290 scopus 로고    scopus 로고
    • Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina
    • Dorrell, M.I. and Friedlander, M. 2006. Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina. Prog. Retin. Eye Res. 25: 277-295.
    • (2006) Prog. Retin. Eye Res , vol.25 , pp. 277-295
    • Dorrell, M.I.1    Friedlander, M.2
  • 14
    • 0036847476 scopus 로고    scopus 로고
    • Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion
    • Dorrell, M.I., Aguilar, E., and Friedlander, M. 2002. Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion. Invest. Ophthalmol. Vis. Sci. 43: 3500-3510.
    • (2002) Invest. Ophthalmol. Vis. Sci , vol.43 , pp. 3500-3510
    • Dorrell, M.I.1    Aguilar, E.2    Friedlander, M.3
  • 17
    • 39049176920 scopus 로고    scopus 로고
    • Notch signaling pathway
    • doi: 10.1126/stke.3642006cm7
    • Ehebauer, M., Hayward, P., and Martinez-Arias, A. 2006. Notch signaling pathway. Sci. STKE 2006: cm7. doi: 10.1126/stke.3642006cm7.
    • (2006) Sci. STKE , vol.2006
    • Ehebauer, M.1    Hayward, P.2    Martinez-Arias, A.3
  • 19
    • 0043062774 scopus 로고    scopus 로고
    • Hey genes in cardiovascular development
    • Fischer, A. and Gessler, M. 2003. Hey genes in cardiovascular development. Trends Cardiovasc. Med. 13: 221-226.
    • (2003) Trends Cardiovasc. Med , vol.13 , pp. 221-226
    • Fischer, A.1    Gessler, M.2
  • 20
    • 1942498907 scopus 로고    scopus 로고
    • The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
    • Fischer, A., Schumacher, N., Maier, M., Sendtner, M., and Gessler, M. 2004. The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes & Dev. 18: 901-911.
    • (2004) Genes & Dev , vol.18 , pp. 901-911
    • Fischer, A.1    Schumacher, N.2    Maier, M.3    Sendtner, M.4    Gessler, M.5
  • 21
    • 1842346472 scopus 로고    scopus 로고
    • Molecular mechanisms of vasculogenesis and embryonic angiogenesis
    • Flamme, I., Frolich, T., and Risau, W. 1997. Molecular mechanisms of vasculogenesis and embryonic angiogenesis. J. Cell. Physiol. 173: 206-210.
    • (1997) J. Cell. Physiol , vol.173 , pp. 206-210
    • Flamme, I.1    Frolich, T.2    Risau, W.3
  • 22
    • 33947330375 scopus 로고    scopus 로고
    • Development of the retinal vasculature
    • Fruttiger, M. 2007. Development of the retinal vasculature. Angiogenesis 10: 77-88.
    • (2007) Angiogenesis , vol.10 , pp. 77-88
    • Fruttiger, M.1
  • 24
    • 0041302198 scopus 로고    scopus 로고
    • Cellular mechanisms in retinal vascular development
    • Gariano, R.F. 2003. Cellular mechanisms in retinal vascular development. Prog. Retin. Eye Res. 22: 295-306.
    • (2003) Prog. Retin. Eye Res , vol.22 , pp. 295-306
    • Gariano, R.F.1
  • 26
    • 33745006167 scopus 로고    scopus 로고
    • Social interactions among epithelial cells during tracheal branching morphogenesis
    • Ghabrial, A.S. and Krasnow, M.A. 2006. Social interactions among epithelial cells during tracheal branching morphogenesis. Nature 441: 746-749.
    • (2006) Nature , vol.441 , pp. 746-749
    • Ghabrial, A.S.1    Krasnow, M.A.2
  • 28
  • 29
    • 33749012860 scopus 로고    scopus 로고
    • The role of the vascular endothelial growth factor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vessel remodeling and endothelial cell functions
    • Hainaud, P., Contreres, J.O., Villemain, A., Liu, L.X., Plouet, J., Tobelem, G., and Dupuy, E. 2006. The role of the vascular endothelial growth factor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vessel remodeling and endothelial cell functions. Cancer Res. 66: 8501-8510.
    • (2006) Cancer Res , vol.66 , pp. 8501-8510
    • Hainaud, P.1    Contreres, J.O.2    Villemain, A.3    Liu, L.X.4    Plouet, J.5    Tobelem, G.6    Dupuy, E.7
  • 30
    • 0141995063 scopus 로고    scopus 로고
    • Glycosylation regulates Notch signalling
    • Haines, N. and Irvine, K.D. 2003. Glycosylation regulates Notch signalling. Nat. Rev. Mol. Cell Biol. 4: 786-797.
    • (2003) Nat. Rev. Mol. Cell Biol , vol.4 , pp. 786-797
    • Haines, N.1    Irvine, K.D.2
  • 31
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D. and Weinberg, R.A. 2000. The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 33
  • 35
    • 0028053438 scopus 로고
    • Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila
    • Hoch, M., Broadie, K., Jackle, H., and Skaer, H. 1994. Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila. Development 120: 3439-3450.
    • (1994) Development , vol.120 , pp. 3439-3450
    • Hoch, M.1    Broadie, K.2    Jackle, H.3    Skaer, H.4
  • 36
    • 33846627870 scopus 로고    scopus 로고
    • Notch expression patterns in the retina: An eye on receptor-ligand distribution during angiogenesis
    • Hofmann, J.J. and Iruela-Arispe, L. 2007. Notch expression patterns in the retina: An eye on receptor-ligand distribution during angiogenesis. Brain Res. Gene Expr. Patterns 7: 461-470.
    • (2007) Brain Res. Gene Expr. Patterns , vol.7 , pp. 461-470
    • Hofmann, J.J.1    Iruela-Arispe, L.2
  • 37
    • 0036920213 scopus 로고    scopus 로고
    • Catching a wave: The oscillator and wavefront that create the zebrafish somite
    • Holley, S.A. and Takeda, H. 2002. Catching a wave: The oscillator and wavefront that create the zebrafish somite. Semin. Cell Dev. Biol. 13: 481-488.
    • (2002) Semin. Cell Dev. Biol , vol.13 , pp. 481-488
    • Holley, S.A.1    Takeda, H.2
  • 38
    • 0030976083 scopus 로고    scopus 로고
    • Maintenance of somite borders in mice requires the Delta homologue DII1
    • Hrabe de Angelis, M., McIntyre II, J., and Gossler, A. 1997. Maintenance of somite borders in mice requires the Delta homologue DII1. Nature 386: 717-721.
    • (1997) Nature , vol.386 , pp. 717-721
    • Hrabe de Angelis, M.1    McIntyre II, J.2    Gossler, A.3
  • 40
    • 0033523278 scopus 로고    scopus 로고
    • Fringe, Notch, and making developmental boundaries
    • Irvine, K.D. 1999. Fringe, Notch, and making developmental boundaries. Curr. Opin. Genet. Dev. 9: 434-441.
    • (1999) Curr. Opin. Genet. Dev , vol.9 , pp. 434-441
    • Irvine, K.D.1
  • 41
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: Multiple effectors of the Notch signaling pathway
    • Iso, T., Kedes, L., and Hamamori, Y. 2003. HES and HERP families: Multiple effectors of the Notch signaling pathway. J. Cell. Physiol. 194: 237-255.
    • (2003) J. Cell. Physiol , vol.194 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 43
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain, R.K. 2003. Molecular regulation of vessel maturation. Nat. Med. 9: 685-693.
    • (2003) Nat. Med , vol.9 , pp. 685-693
    • Jain, R.K.1
  • 45
    • 0842285690 scopus 로고    scopus 로고
    • Pathogenic mutations associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy differently affect Jagged1 binding and Notch3 activity via the RBP/JK signaling pathway
    • Joutel, A., Monet, M., Domenga, V., Riant, F., and Tournier-Lasserve, E. 2004. Pathogenic mutations associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy differently affect Jagged1 binding and Notch3 activity via the RBP/JK signaling pathway. Am. J. Hum. Genet. 74: 338-347.
    • (2004) Am. J. Hum. Genet , vol.74 , pp. 338-347
    • Joutel, A.1    Monet, M.2    Domenga, V.3    Riant, F.4    Tournier-Lasserve, E.5
  • 47
    • 0037168593 scopus 로고    scopus 로고
    • A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling
    • Karlstrom, H., Beatus, P., Dannaeus, K., Chapman, G., Lendahl, U., and Lundkvist, J. 2002. A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling. Proc. Natl. Acad. Sci. 99: 17119-17124.
    • (2002) Proc. Natl. Acad. Sci , vol.99 , pp. 17119-17124
    • Karlstrom, H.1    Beatus, P.2    Dannaeus, K.3    Chapman, G.4    Lendahl, U.5    Lundkvist, J.6
  • 51
    • 5444242184 scopus 로고    scopus 로고
    • Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
    • Krebs, L.T., Shutter, J.R., Tanigaki, K., Honjo, T., Stark, K.L., and Gridley, T. 2004. Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes & Dev. 18: 2469-2473.
    • (2004) Genes & Dev , vol.18 , pp. 2469-2473
    • Krebs, L.T.1    Shutter, J.R.2    Tanigaki, K.3    Honjo, T.4    Stark, K.L.5    Gridley, T.6
  • 52
    • 0036747296 scopus 로고    scopus 로고
    • Keeping a good pathway down: Transcriptional repression of Notch pathway target genes by CSL proteins
    • Lai, E.C. 2002a. Keeping a good pathway down: Transcriptional repression of Notch pathway target genes by CSL proteins. EMBO Rep. 3: 840-845.
    • (2002) EMBO Rep , vol.3 , pp. 840-845
    • Lai, E.C.1
  • 53
    • 0037154292 scopus 로고    scopus 로고
    • Protein degradation: Four E3s for the Notch pathway
    • Lai, E.C. 2002b. Protein degradation: Four E3s for the Notch pathway. Curr. Biol. 12: R74-R78.
    • (2002) Curr. Biol , vol.12
    • Lai, E.C.1
  • 54
    • 1642382833 scopus 로고    scopus 로고
    • Notch signaling: Control of cell communication and cell fate
    • Lai, E.C. 2004. Notch signaling: Control of cell communication and cell fate. Development 131: 965-973.
    • (2004) Development , vol.131 , pp. 965-973
    • Lai, E.C.1
  • 55
  • 56
    • 0036070186 scopus 로고    scopus 로고
    • sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation
    • Lawson, N.D., Vogel, A.M., and Weinstein, B.M. 2002. sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev. Cell 3: 127-136.
    • (2002) Dev. Cell , vol.3 , pp. 127-136
    • Lawson, N.D.1    Vogel, A.M.2    Weinstein, B.M.3
  • 57
    • 0037382585 scopus 로고    scopus 로고
    • Notch signaling: Endocytosis makes Delta signal better
    • doi: 10.1016/S0960-9822(03)00199-4
    • Le Borgne, R. and Schweisguth, F. 2003. Notch signaling: Endocytosis makes Delta signal better. Curr. Biol. 13: R273-R275. doi: 10.1016/S0960-9822(03)00199-4.
    • (2003) Curr. Biol , vol.13
    • Le Borgne, R.1    Schweisguth, F.2
  • 58
    • 18844414504 scopus 로고    scopus 로고
    • The roles of receptor and ligand endocytosis in regulating Notch signaling
    • Le Borgne, R., Bardin, A., and Schweisguth, F. 2005. The roles of receptor and ligand endocytosis in regulating Notch signaling. Development 132: 1751-1762.
    • (2005) Development , vol.132 , pp. 1751-1762
    • Le Borgne, R.1    Bardin, A.2    Schweisguth, F.3
  • 62
    • 0037216703 scopus 로고    scopus 로고
    • Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: Implications for modulating arteriogenesis and angiogenesis
    • Liu, Z.J., Shirakawa, T., Li, Y., Soma, A., Oka, M., Dotto, G.P., Fairman, R.M., Velazquez, O.C., and Herlyn, M. 2003. Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: Implications for modulating arteriogenesis and angiogenesis. Mol. Cell. Biol. 23: 14-25.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 14-25
    • Liu, Z.J.1    Shirakawa, T.2    Li, Y.3    Soma, A.4    Oka, M.5    Dotto, G.P.6    Fairman, R.M.7    Velazquez, O.C.8    Herlyn, M.9
  • 64
    • 4444259419 scopus 로고    scopus 로고
    • Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-Jκ
    • MacKenzie, F., Duriez, P., Larrivee, B., Chang, L., Pollet, I., Wong, F., Yip, C., and Karsan, A. 2004. Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-Jκ. Blood 104: 1760-1768.
    • (2004) Blood , vol.104 , pp. 1760-1768
    • MacKenzie, F.1    Duriez, P.2    Larrivee, B.3    Chang, L.4    Pollet, I.5    Wong, F.6    Yip, C.7    Karsan, A.8
  • 65
    • 0035753241 scopus 로고    scopus 로고
    • Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis
    • Mailhos, C., Modlich, U., Lewis, J., Harris, A., Bicknell, R., and Ish-Horowicz, D. 2001. Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation 69: 135-144.
    • (2001) Differentiation , vol.69 , pp. 135-144
    • Mailhos, C.1    Modlich, U.2    Lewis, J.3    Harris, A.4    Bicknell, R.5    Ish-Horowicz, D.6
  • 66
    • 0036778127 scopus 로고    scopus 로고
    • CSL-independent Notch signalling: A checkpoint in cell fate decisions during development?
    • Martinez Arias, A., Zecchini, V., and Brennan, K. 2002. CSL-independent Notch signalling: A checkpoint in cell fate decisions during development? Curr. Opin. Genet. Dev. 12: 524-533.
    • (2002) Curr. Opin. Genet. Dev , vol.12 , pp. 524-533
    • Martinez Arias, A.1    Zecchini, V.2    Brennan, K.3
  • 67
    • 0036339631 scopus 로고    scopus 로고
    • A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency
    • McCright, B., Lozier, J., and Gridley, T. 2002. A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development 129: 1075-1082.
    • (2002) Development , vol.129 , pp. 1075-1082
    • McCright, B.1    Lozier, J.2    Gridley, T.3
  • 68
    • 0037069322 scopus 로고    scopus 로고
    • Analysis of cardiovascular phenotype and genotype-phenotype correlation in individuals with a JAG1 mutation and/or Alagille syndrome
    • McElhinney, D.B., Krantz, I.D., Bason, L., Piccoli, D.A., Emerick, K.M., Spinner, N.B., and Goldmuntz, E. 2002. Analysis of cardiovascular phenotype and genotype-phenotype correlation in individuals with a JAG1 mutation and/or Alagille syndrome. Circulation 106: 2567-2574.
    • (2002) Circulation , vol.106 , pp. 2567-2574
    • McElhinney, D.B.1    Krantz, I.D.2    Bason, L.3    Piccoli, D.A.4    Emerick, K.M.5    Spinner, N.B.6    Goldmuntz, E.7
  • 69
    • 0347995018 scopus 로고    scopus 로고
    • VEGF(121) and VEGF(165) regulate blood vessel diameter through vascular endothelial growth factor receptor 2 in an in vitro angiogenesis model
    • Nakatsu, M.N., Sainson, R.C., Perez-del-Pulgar, S., Aoto, J.N., Aitkenhead, M., Taylor, K.L., Carpenter, P.M., and Hughes, C.C. 2003. VEGF(121) and VEGF(165) regulate blood vessel diameter through vascular endothelial growth factor receptor 2 in an in vitro angiogenesis model. Lab. Invest. 83: 1873-1885.
    • (2003) Lab. Invest , vol.83 , pp. 1873-1885
    • Nakatsu, M.N.1    Sainson, R.C.2    Perez-del-Pulgar, S.3    Aoto, J.N.4    Aitkenhead, M.5    Taylor, K.L.6    Carpenter, P.M.7    Hughes, C.C.8
  • 70
    • 33846968807 scopus 로고    scopus 로고
    • DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur
    • Nichols, J.T., Miyamoto, A., Olsen, S.L., D'Souza, B., Yao, C., and Weinmaster, G. 2007a. DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur. J. Cell Biol. 176: 445-458.
    • (2007) J. Cell Biol , vol.176 , pp. 445-458
    • Nichols, J.T.1    Miyamoto, A.2    Olsen, S.L.3    D'Souza, B.4    Yao, C.5    Weinmaster, G.6
  • 71
    • 34447509872 scopus 로고    scopus 로고
    • Notch signaling - Constantly on the move
    • Nichols, J.T., Miyamoto, A., and Weinmaster, G. 2007b. Notch signaling - Constantly on the move. Traffic 8: 959-969.
    • (2007) Traffic , vol.8 , pp. 959-969
    • Nichols, J.T.1    Miyamoto, A.2    Weinmaster, G.3
  • 73
    • 4744358492 scopus 로고    scopus 로고
    • Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: Role of p21Cip1 repression
    • Noseda, M., Chang, L., McLean, G., Grim, J.E., Clurman, B.E., Smith, L.L., and Karsan, A. 2004. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: Role of p21Cip1 repression. Mol. Cell. Biol. 24: 8813-8822.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 8813-8822
    • Noseda, M.1    Chang, L.2    McLean, G.3    Grim, J.E.4    Clurman, B.E.5    Smith, L.L.6    Karsan, A.7
  • 75
    • 9544221645 scopus 로고    scopus 로고
    • Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells
    • Overstreet, E., Fitch, E., and Fischer, J.A. 2004. Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells. Development 131: 5355-5366.
    • (2004) Development , vol.131 , pp. 5355-5366
    • Overstreet, E.1    Fitch, E.2    Fischer, J.A.3
  • 76
    • 25444506836 scopus 로고    scopus 로고
    • Up-regulation of Delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
    • Patel, N.S., Li, J.L., Generali, D., Poulsom, R., Cranston, D.W., and Harris, A.L. 2005. Up-regulation of Delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res. 65: 8690-8697.
    • (2005) Cancer Res , vol.65 , pp. 8690-8697
    • Patel, N.S.1    Li, J.L.2    Generali, D.3    Poulsom, R.4    Cranston, D.W.5    Harris, A.L.6
  • 78
    • 27144558408 scopus 로고    scopus 로고
    • The interplay between DSL proteins and ubiquitin ligases in Notch signaling
    • Pitsouli, C. and Delidakis, C. 2005. The interplay between DSL proteins and ubiquitin ligases in Notch signaling. Development 132: 4041-4050.
    • (2005) Development , vol.132 , pp. 4041-4050
    • Pitsouli, C.1    Delidakis, C.2
  • 79
    • 0038115065 scopus 로고    scopus 로고
    • The segmentation clock: Converting embryonic time into spatial pattern
    • Pourquie, O. 2003. The segmentation clock: Converting embryonic time into spatial pattern. Science 301: 328-330.
    • (2003) Science , vol.301 , pp. 328-330
    • Pourquie, O.1
  • 80
    • 1542317449 scopus 로고    scopus 로고
    • Notch regulation of lymphocyte development and function
    • Radtke, F., Wilson, A., Mancini, S.J., and MacDonald, H.R. 2004. Notch regulation of lymphocyte development and function. Nat. Immunol. 5: 247-253.
    • (2004) Nat. Immunol , vol.5 , pp. 247-253
    • Radtke, F.1    Wilson, A.2    Mancini, S.J.3    MacDonald, H.R.4
  • 81
    • 11144250929 scopus 로고    scopus 로고
    • Genetic control of cell intercalation during tracheal morphogenesis in Drosophila
    • Ribeiro, C., Neumann, M., and Affolter, M. 2004. Genetic control of cell intercalation during tracheal morphogenesis in Drosophila. Curr. Biol. 14: 2197-2207.
    • (2004) Curr. Biol , vol.14 , pp. 2197-2207
    • Ribeiro, C.1    Neumann, M.2    Affolter, M.3
  • 84
    • 0037221480 scopus 로고    scopus 로고
    • Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
    • Ruchoux, M.M., Domenga, V., Brulin, P., Maciazek, J., Limol, S., Tournier-Lasserve, E., and Joutel, A. 2003. Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Am. J. Pathol. 162: 329-342.
    • (2003) Am. J. Pathol , vol.162 , pp. 329-342
    • Ruchoux, M.M.1    Domenga, V.2    Brulin, P.3    Maciazek, J.4    Limol, S.5    Tournier-Lasserve, E.6    Joutel, A.7
  • 85
    • 0037108152 scopus 로고    scopus 로고
    • Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis
    • Ruhrberg, C., Gerhardt, H., Golding, M., Watson, R., Ioannidou, S., Fujisawa, H., Betsholtz, C., and Shima, D.T. 2002. Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis. Genes & Dev. 16: 2684-2698.
    • (2002) Genes & Dev , vol.16 , pp. 2684-2698
    • Ruhrberg, C.1    Gerhardt, H.2    Golding, M.3    Watson, R.4    Ioannidou, S.5    Fujisawa, H.6    Betsholtz, C.7    Shima, D.T.8
  • 86
    • 20444495706 scopus 로고    scopus 로고
    • Cell-autonomous Notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis
    • Sainson, R.C., Aoto, J., Nakatsu, M.N., Holderfield, M., Conn, E., Koller, E., and Hughes, C.C. 2005. Cell-autonomous Notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis. FASEB J. 19: 1027-1029.
    • (2005) FASEB J , vol.19 , pp. 1027-1029
    • Sainson, R.C.1    Aoto, J.2    Nakatsu, M.N.3    Holderfield, M.4    Conn, E.5    Koller, E.6    Hughes, C.C.7
  • 87
    • 11144350287 scopus 로고    scopus 로고
    • Drosophila Nedd4 regulates endocytosis of Notch and suppresses its ligand-independent activation
    • Sakata, T., Sakaguchi, H., Tsuda, L., Higashitani, A., Aigaki, T., Matsuno, K., and Hayashi, S. 2004. Drosophila Nedd4 regulates endocytosis of Notch and suppresses its ligand-independent activation. Curr. Biol. 14: 2228-2236.
    • (2004) Curr. Biol , vol.14 , pp. 2228-2236
    • Sakata, T.1    Sakaguchi, H.2    Tsuda, L.3    Higashitani, A.4    Aigaki, T.5    Matsuno, K.6    Hayashi, S.7
  • 90
    • 1242265691 scopus 로고    scopus 로고
    • Regulation of Notch signaling activity
    • doi: 10.1016/j.cub.2004.01.023
    • Schweisguth, F. 2004. Regulation of Notch signaling activity. Curr. Biol. 14: R129-R138. doi: 10.1016/j.cub.2004.01.023.
    • (2004) Curr. Biol , vol.14
    • Schweisguth, F.1
  • 91
    • 0041355557 scopus 로고    scopus 로고
    • Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration
    • Selkoe, D. and Kopan, R. 2003. Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration. Annu. Rev. Neurosci. 26: 565-597.
    • (2003) Annu. Rev. Neurosci , vol.26 , pp. 565-597
    • Selkoe, D.1    Kopan, R.2
  • 93
    • 0037547158 scopus 로고    scopus 로고
    • Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways
    • Shi, S. and Stanley, P. 2003. Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways. Proc. Natl. Acad. Sci. 100: 5234-5239.
    • (2003) Proc. Natl. Acad. Sci , vol.100 , pp. 5234-5239
    • Shi, S.1    Stanley, P.2
  • 95
    • 33847039645 scopus 로고    scopus 로고
    • Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries
    • Siekmann, A.F. and Lawson, N.D. 2007. Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature 445: 781-784.
    • (2007) Nature , vol.445 , pp. 781-784
    • Siekmann, A.F.1    Lawson, N.D.2
  • 97
    • 0029074024 scopus 로고
    • Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia
    • Stone, J., Itin, A., Alon, T., Pe'er, J., Gnessin, H., Chan-Ling, T., and Keshet, E. 1995. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J. Neurosci. 15: 4738-4747.
    • (1995) J. Neurosci , vol.15 , pp. 4738-4747
    • Stone, J.1    Itin, A.2    Alon, T.3    Pe'er, J.4    Gnessin, H.5    Chan-Ling, T.6    Keshet, E.7
  • 98
    • 0027219557 scopus 로고
    • Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo
    • Struhl, G., Fitzgerald, K., and Greenwald, I. 1993. Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell 74: 331-345.
    • (1993) Cell , vol.74 , pp. 331-345
    • Struhl, G.1    Fitzgerald, K.2    Greenwald, I.3
  • 99
  • 101
    • 0036433637 scopus 로고    scopus 로고
    • Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression
    • Taylor, K.L., Henderson, A.M., and Hughes, C.C. 2002. Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression. Microvasc. Res. 64: 372-383.
    • (2002) Microvasc. Res , vol.64 , pp. 372-383
    • Taylor, K.L.1    Henderson, A.M.2    Hughes, C.C.3
  • 102
    • 12344309339 scopus 로고    scopus 로고
    • Epsin potentiates Notch pathway activity in Drosophila and C. elegans
    • Tian, X., Hansen, D., Schedl, T., and Skeath, J.B. 2004. Epsin potentiates Notch pathway activity in Drosophila and C. elegans. Development 131: 5807-5815.
    • (2004) Development , vol.131 , pp. 5807-5815
    • Tian, X.1    Hansen, D.2    Schedl, T.3    Skeath, J.B.4
  • 104
    • 0035826844 scopus 로고    scopus 로고
    • Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium
    • Uyttendaele, H., Ho, J., Rossant, J., and Kitajewski, J. 2001. Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc. Natl. Acad. Sci. 98: 5643-5648.
    • (2001) Proc. Natl. Acad. Sci , vol.98 , pp. 5643-5648
    • Uyttendaele, H.1    Ho, J.2    Rossant, J.3    Kitajewski, J.4
  • 106
    • 0033972640 scopus 로고    scopus 로고
    • Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules
    • Wan, S., Cato, A.M., and Skaer, H. 2000. Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules. Dev. Biol. 217: 153-165.
    • (2000) Dev. Biol , vol.217 , pp. 153-165
    • Wan, S.1    Cato, A.M.2    Skaer, H.3
  • 107
    • 9444297354 scopus 로고    scopus 로고
    • Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch
    • Wang, W. and Struhl, G. 2004. Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch. Development 131: 5367-5380.
    • (2004) Development , vol.131 , pp. 5367-5380
    • Wang, W.1    Struhl, G.2
  • 108
    • 21644462494 scopus 로고    scopus 로고
    • Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila
    • Wang, W. and Struhl, G. 2005. Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila. Development 132: 2883-2894.
    • (2005) Development , vol.132 , pp. 2883-2894
    • Wang, W.1    Struhl, G.2
  • 109
    • 0033920919 scopus 로고    scopus 로고
    • Notch signal transduction: A real rip and more
    • Weinmaster, G. 2000. Notch signal transduction: A real rip and more. Curr. Opin. Genet. Dev. 10: 363-369.
    • (2000) Curr. Opin. Genet. Dev , vol.10 , pp. 363-369
    • Weinmaster, G.1
  • 110
    • 27144452592 scopus 로고    scopus 로고
    • Endocytic regulation of Notch activation and down-regulation
    • Wilkin, M.B. and Baron, M. 2005. Endocytic regulation of Notch activation and down-regulation. Mol. Membr. Biol. 22: 279-289.
    • (2005) Mol. Membr. Biol , vol.22 , pp. 279-289
    • Wilkin, M.B.1    Baron, M.2
  • 112
    • 31544448010 scopus 로고    scopus 로고
    • Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function
    • Williams, C.K., Li, J.L., Murga, M., Harris, A.L., and Tosato, G. 2006. Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function. Blood 107: 931-939.
    • (2006) Blood , vol.107 , pp. 931-939
    • Williams, C.K.1    Li, J.L.2    Murga, M.3    Harris, A.L.4    Tosato, G.5
  • 114
    • 18344377007 scopus 로고    scopus 로고
    • Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
    • You, L.R., Lin, F.J., Lee, C.T., DeMayo, F.J., Tsai, M.J., and Tsai, S.Y. 2005. Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature 435: 98-104.
    • (2005) Nature , vol.435 , pp. 98-104
    • You, L.R.1    Lin, F.J.2    Lee, C.T.3    DeMayo, F.J.4    Tsai, M.J.5    Tsai, S.Y.6
  • 115
    • 0034016527 scopus 로고    scopus 로고
    • Cell fate choices in Drosophila tracheal morphogenesis
    • Zelzer, E. and Shilo, B.Z. 2000. Cell fate choices in Drosophila tracheal morphogenesis. Bioessays 22: 219-226.
    • (2000) Bioessays , vol.22 , pp. 219-226
    • Zelzer, E.1    Shilo, B.Z.2
  • 117
    • 0034629325 scopus 로고    scopus 로고
    • gridlock, an HLH gene required for assembly of the aorta in zebrafish
    • Zhong, T.P., Rosenberg, M., Mohideen, M.A., Weinstein, B., and Fishman, M.C. 2000. gridlock, an HLH gene required for assembly of the aorta in zebrafish. Science 287: 1820-1824.
    • (2000) Science , vol.287 , pp. 1820-1824
    • Zhong, T.P.1    Rosenberg, M.2    Mohideen, M.A.3    Weinstein, B.4    Fishman, M.C.5
  • 118
    • 0035829517 scopus 로고    scopus 로고
    • Gridlock signalling pathway fashions the first embryonic artery
    • Zhong, T.P., Childs, S., Leu, J.P., and Fishman, M.C. 2001. Gridlock signalling pathway fashions the first embryonic artery. Nature 414: 216-220.
    • (2001) Nature , vol.414 , pp. 216-220
    • Zhong, T.P.1    Childs, S.2    Leu, J.P.3    Fishman, M.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.