메뉴 건너뛰기




Volumn 2, Issue 9, 2007, Pages 1185-1203

Nicotinic receptors as targets for therapeutic discovery

Author keywords

Acetylcholine; Analgesia; Cognition; Depression; Inflammation; Neurodegeneration; Nicotinic receptors; Schizophrenia

Indexed keywords

3 (2 AZETIDINYLMETHOXY)PYRIDINE; 3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; 3 ETHYNYL 5 (1 METHYL 2 PYRROLIDINYL)PYRIDINE; ABT 894; AMFEBUTAMONE; ANTIDEPRESSANT AGENT; ANTIINFLAMMATORY AGENT; AZD 3480; BUNGAROTOXIN RECEPTOR; BUNGAROTOXIN RECEPTOR STIMULATING AGENT; CAP 55; CHOLINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CHOLINERGIC RECEPTOR STIMULATING AGENT; ISPRONICLINE; LEVODOPA; MECAMYLAMINE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; NICOTINE; NICOTINE PATCH; NICOTINIC AGENT; NICOTINIC RECEPTOR; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; SPIRO[1 AZABICYCLO[2.2.2]OCTANE 3,2' THIAZOLIDINE] 2' ONE; SSR 180711A; TC 1698; TC 2696; UNCLASSIFIED DRUG; UNINDEXED DRUG; VENLAFAXINE;

EID: 34848883088     PISSN: 17460441     EISSN: None     Source Type: Journal    
DOI: 10.1517/17460441.2.9.1185     Document Type: Review
Times cited : (37)

References (188)
  • 1
    • 33749440087 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors
    • ISHII M, KURACHI Y: Muscarinic acetylcholine receptors. Curr. Pharm. Des. (2006) 12:3573-3581.
    • (2006) Curr. Pharm. Des , vol.12 , pp. 3573-3581
    • ISHII, M.1    KURACHI, Y.2
  • 2
    • 33847029091 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system
    • DANI JA, BERTRAND D: Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system. Annu. Rev. Pharmacol. Toxicol. (2007) 47:699-729.
    • (2007) Annu. Rev. Pharmacol. Toxicol , vol.47 , pp. 699-729
    • DANI, J.A.1    BERTRAND, D.2
  • 3
    • 33747422892 scopus 로고    scopus 로고
    • Brain nicotinic acetylcholine receptors: Native subtypes and their relevance
    • GOTTI C, ZOLI M, CLEMENTI F: Brain nicotinic acetylcholine receptors: native subtypes and their relevance. Trends Pharmacol. Sci. (2006) 27:482-491.
    • (2006) Trends Pharmacol. Sci , vol.27 , pp. 482-491
    • GOTTI, C.1    ZOLI, M.2    CLEMENTI, F.3
  • 4
    • 0032970174 scopus 로고    scopus 로고
    • International union of pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits
    • LUKAS RJ, CHANGEUX JP, LE NOVERE N et al.: International union of pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits. Pharmacol. Rev. (1999) 51:397-401.
    • (1999) Pharmacol. Rev , vol.51 , pp. 397-401
    • LUKAS, R.J.1    CHANGEUX, J.P.2    LE NOVERE, N.3
  • 7
    • 2942640608 scopus 로고    scopus 로고
    • Recent developments in the synthesis of nicotinic acetylcholine receptor ligands
    • BREINING SR: Recent developments in the synthesis of nicotinic acetylcholine receptor ligands. Curr. Top. Med. Chem. (2004) 4:609-629.
    • (2004) Curr. Top. Med. Chem , vol.4 , pp. 609-629
    • BREINING, S.R.1
  • 8
    • 3042776739 scopus 로고    scopus 로고
    • TC- 1734: An orally active ncuronal nicotinic acetylcholine receptor modulator with antidepressant, neuroprotcctive and long-lasting cognitive effects
    • GATTO GJ, BOHME GA, CALDWELL WS et al.: TC- 1734: an orally active ncuronal nicotinic acetylcholine receptor modulator with antidepressant, neuroprotcctive and long-lasting cognitive effects. CNS Drug Rev. (2004) 10:147-166.
    • (2004) CNS Drug Rev , vol.10 , pp. 147-166
    • GATTO, G.J.1    BOHME, G.A.2    CALDWELL, W.S.3
  • 9
    • 33847351996 scopus 로고    scopus 로고
    • Schizophrenia and the α7 nicotinic acetylcholine receptor
    • MARTIN LF, FREEDMAN R: Schizophrenia and the α7 nicotinic acetylcholine receptor. Int. Rev. Neurobiol. (2007) 78:225-246.
    • (2007) Int. Rev. Neurobiol , vol.78 , pp. 225-246
    • MARTIN, L.F.1    FREEDMAN, R.2
  • 10
    • 33947239151 scopus 로고    scopus 로고
    • Controlling inflammation: The cholinergic anti-inflammatory pathway
    • PAVLOV VA, TRACEY KJ: Controlling inflammation: the cholinergic anti-inflammatory pathway. Biochem. Soc. Trans. (2006) 34:1037-1040.
    • (2006) Biochem. Soc. Trans , vol.34 , pp. 1037-1040
    • PAVLOV, V.A.1    TRACEY, K.J.2
  • 11
    • 31144439038 scopus 로고    scopus 로고
    • Striatal α6* nicotinic acetylcholine receptors: Potential targets for Parkinssons disease therapy
    • QUIK M, MCINTOSH JM: Striatal α6* nicotinic acetylcholine receptors: potential targets for Parkinssons disease therapy. J. Pharmacol. Exp. Ther. (2006) 316:481-489.
    • (2006) J. Pharmacol. Exp. Ther , vol.316 , pp. 481-489
    • QUIK, M.1    MCINTOSH, J.M.2
  • 12
    • 33845863396 scopus 로고    scopus 로고
    • Exploitation of the nicotinic anti-inflammatory pathway for the treatment of epithelial inflammatory diseases
    • SCOTT DA, MARTIN M: Exploitation of the nicotinic anti-inflammatory pathway for the treatment of epithelial inflammatory diseases. World J Gastroenterol. (2006) 12:7451-7459.
    • (2006) World J Gastroenterol , vol.12 , pp. 7451-7459
    • SCOTT, D.A.1    MARTIN, M.2
  • 13
    • 0029982982 scopus 로고    scopus 로고
    • Smoking may prevent pouchitis in patients with restorative proctocolectomy for ulcerative colitis
    • MERRETT MN, MORTENSEN N, KEITLEWELL M, JEWELL DO: Smoking may prevent pouchitis in patients with restorative proctocolectomy for ulcerative colitis. Gut (1996) 38:362-364.
    • (1996) Gut , vol.38 , pp. 362-364
    • MERRETT, M.N.1    MORTENSEN, N.2    KEITLEWELL, M.3    JEWELL, D.O.4
  • 14
    • 0031827820 scopus 로고    scopus 로고
    • Nicotine-induced modulation of T cell function. Implications for inflammation and infection
    • SOPORI ML, KOZAK W, SAVAGE SM, GENG Y, KLUGER MJ: Nicotine-induced modulation of T cell function. Implications for inflammation and infection. Adv. Exp. Med. Biol. (1998) 437:279-289.
    • (1998) Adv. Exp. Med. Biol , vol.437 , pp. 279-289
    • SOPORI, M.L.1    KOZAK, W.2    SAVAGE, S.M.3    GENG, Y.4    KLUGER, M.J.5
  • 15
  • 16
    • 0038721840 scopus 로고    scopus 로고
    • Effect of (+/-)-epibatidine, a nicotinic agonist, on the central pathways controlling voiding function in the rat
    • LEE SJ, NAKAMURA Y, DE GROAT WC: Effect of (+/-)-epibatidine, a nicotinic agonist, on the central pathways controlling voiding function in the rat. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2003) 285:R84-R90.
    • (2003) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.285
    • LEE, S.J.1    NAKAMURA, Y.2    DE GROAT, W.C.3
  • 17
    • 8344256524 scopus 로고    scopus 로고
    • Nicotine effects on skin: Are they positive or negative?
    • MISERY L: Nicotine effects on skin: are they positive or negative? Exp. Dermatol. (2004) 13:665-670.
    • (2004) Exp. Dermatol , vol.13 , pp. 665-670
    • MISERY, L.1
  • 19
    • 8844276724 scopus 로고    scopus 로고
    • Alteration of liippocampal cell proliferation in mice lacking the β2 subunit of the neuronal nicotinic acetylcholine receptor
    • HARRIST A, BEECH RD, KING SL et al.: Alteration of liippocampal cell proliferation in mice lacking the β2 subunit of the neuronal nicotinic acetylcholine receptor. Synapse (2004) 54:200-206.
    • (2004) Synapse , vol.54 , pp. 200-206
    • HARRIST, A.1    BEECH, R.D.2    KING, S.L.3
  • 20
    • 32844461888 scopus 로고    scopus 로고
    • Nicotinic effects on cognitive function: Behavioral characterization, pharmacological specification, and anatomic localization
    • LEVIN ED, MCCLERNON FJ, REZVANI AH: Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization. Psychopbarmacology (Berl.) (2006) 184(3-4):523-539.
    • (2006) Psychopbarmacology (Berl.) , vol.184 , Issue.3-4 , pp. 523-539
    • LEVIN, E.D.1    MCCLERNON, F.J.2    REZVANI, A.H.3
  • 21
    • 0036237780 scopus 로고    scopus 로고
    • Persistence of nicotinic agonist RJR 2403-induced working memory improvement in rats
    • LEVIN ED, CHRISTOPHER NC: Persistence of nicotinic agonist RJR 2403-induced working memory improvement in rats. Drug Dev. Res. (2002) 55:97-103.
    • (2002) Drug Dev. Res , vol.55 , pp. 97-103
    • LEVIN, E.D.1    CHRISTOPHER, N.C.2
  • 22
    • 2942566065 scopus 로고    scopus 로고
    • Participation of hippocampal nicotinic receptors in acquisition, consolidation and retrieval of memory for one trial inhibitory avoidance in rats
    • MARTI BARROS DM, RAMIREZ MR, DOS REIS EA, IZQUIERDO I: Participation of hippocampal nicotinic receptors in acquisition, consolidation and retrieval of memory for one trial inhibitory avoidance in rats. Neuroscience (2004) 126:651-656.
    • (2004) Neuroscience , vol.126 , pp. 651-656
    • MARTI BARROS DM, R.M.1    DOS REIS EA, I.I.2
  • 23
    • 20544460348 scopus 로고    scopus 로고
    • Long-lasting cognitive improvement with nicotinic receptor agonists: Mechanisms of pharmacokinetic-pharmacodynamic discordance
    • BUCCAFUSCO JJ, BENCHERIF M, LETCHWORTH SR, LIPPIELLO PM: Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance. Trends Pharm. Sci. (2005) 26:352-360.
    • (2005) Trends Pharm. Sci , vol.26 , pp. 352-360
    • BUCCAFUSCO, J.J.1    BENCHERIF, M.2    LETCHWORTH, S.R.3    LIPPIELLO, P.M.4
  • 25
    • 0034849954 scopus 로고    scopus 로고
    • Effects of chronic nicotine and methylphenidate in adults with attention deficit/ hyperactivity disorder
    • LEVIN ED, CONNERS CK, SILVA D, CANU W, MARCH J: Effects of chronic nicotine and methylphenidate in adults with attention deficit/ hyperactivity disorder. Exp. Clin. Psychopharmacol. (2001) 9:83-90.
    • (2001) Exp. Clin. Psychopharmacol , vol.9 , pp. 83-90
    • LEVIN, E.D.1    CONNERS, C.K.2    SILVA, D.3    CANU, W.4    MARCH, J.5
  • 26
    • 0032530368 scopus 로고    scopus 로고
    • Nicotinic stimulation produces multiple forms of increased glutamatergic synaptic transmission
    • RADCLIFF KA, DANI JA: Nicotinic stimulation produces multiple forms of increased glutamatergic synaptic transmission. J. Neurosci. (1998) 18:7075-7083.
    • (1998) J. Neurosci , vol.18 , pp. 7075-7083
    • RADCLIFF, K.A.1    DANI, J.A.2
  • 27
    • 0141523154 scopus 로고    scopus 로고
    • Novel modulatory mechanisms revealed by the sustained application of nicotine in the guinea-pig hippocampus in vitro
    • MANN EO, GREENFIELD SA: Novel modulatory mechanisms revealed by the sustained application of nicotine in the guinea-pig hippocampus in vitro. J. Physiol. (2003) 551:539-550.
    • (2003) J. Physiol , vol.551 , pp. 539-550
    • MANN, E.O.1    GREENFIELD, S.A.2
  • 28
    • 0242720568 scopus 로고    scopus 로고
    • Epibatidine induces long-term potentiation (LTP) via activation of α4β2 nicotinic acetylcholine receptors (nAChRs) in vivo in the intact mouse dentate gyrus: Both α7 and α4β2 nAChRs essential to nicotinic LTP
    • MATSUYAMA S, MATSUMOTO A: Epibatidine induces long-term potentiation (LTP) via activation of α4β2 nicotinic acetylcholine receptors (nAChRs) in vivo in the intact mouse dentate gyrus: both α7 and α4β2 nAChRs essential to nicotinic LTP. J. Pharm. Sci. (2003) 93:180-187.
    • (2003) J. Pharm. Sci , vol.93 , pp. 180-187
    • MATSUYAMA, S.1    MATSUMOTO, A.2
  • 29
    • 0032852717 scopus 로고    scopus 로고
    • Acute and chronic nicotine exposure differentially facilitate the induction of LTP
    • FUJII S, JI Z, MORITA N, SUMIKAWA K: Acute and chronic nicotine exposure differentially facilitate the induction of LTP. Brain Res. (1999) 846:137-143.
    • (1999) Brain Res , vol.846 , pp. 137-143
    • FUJII, S.1    JI, Z.2    MORITA, N.3    SUMIKAWA, K.4
  • 30
    • 0034727894 scopus 로고    scopus 로고
    • Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus
    • KENNY PJ, FILE SE, RATTRAY M: Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus. Brain Res. Mol. Brain Res. (2000) 85:234-238.
    • (2000) Brain Res. Mol. Brain Res , vol.85 , pp. 234-238
    • KENNY, P.J.1    FILE, S.E.2    RATTRAY, M.3
  • 32
    • 0037083689 scopus 로고    scopus 로고
    • Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo
    • JONNALA RR, TERRY AV Jr, BUCCAFUSCO JJ: Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo. Life Sci. (2002) 70:1543-1554.
    • (2002) Life Sci , vol.70 , pp. 1543-1554
    • JONNALA, R.R.1    TERRY Jr, A.V.2    BUCCAFUSCO, J.J.3
  • 33
    • 11844302849 scopus 로고    scopus 로고
    • Repeated nicotine exposure in rats: Effects on memory function, cholinergic markers and nerve growth Factor
    • HERNANDEZ CM, TERRY AV JR: Repeated nicotine exposure in rats: effects on memory function, cholinergic markers and nerve growth Factor. Neuroscience (2005) 130:997-1012.
    • (2005) Neuroscience , vol.130 , pp. 997-1012
    • HERNANDEZ, C.M.1    TERRY, A.J.2
  • 34
    • 0028330489 scopus 로고
    • NMDA potentiates NGF-induced sprouting of septal cholinergic fibres
    • HEISENBERG CP, COOPER JD, BERKE J, SOFRONIEW MV: NMDA potentiates NGF-induced sprouting of septal cholinergic fibres. Neuroreport (1994) 5:413-416.
    • (1994) Neuroreport , vol.5 , pp. 413-416
    • HEISENBERG, C.P.1    COOPER, J.D.2    BERKE, J.3    SOFRONIEW, M.V.4
  • 35
    • 0028284187 scopus 로고
    • Effects of chronic nerve growth factor treatment on hippocampal [3H]cytisine/nicotinic binding sites and presynaptic nicotinic receptor function following fimbrial transections
    • LAPCHAK PA, ARAUJO DM, HEFTI F: Effects of chronic nerve growth factor treatment on hippocampal [3H]cytisine/nicotinic binding sites and presynaptic nicotinic receptor function following fimbrial transections. Neuroscience (1994) 60:293-298.
    • (1994) Neuroscience , vol.60 , pp. 293-298
    • LAPCHAK, P.A.1    ARAUJO, D.M.2    HEFTI, F.3
  • 36
    • 19444377836 scopus 로고    scopus 로고
    • Desensitized nicotinic receptors in brain
    • WANG H, SUN X- Desensitized nicotinic receptors in brain. Brain Res. Brain Res. Rev. (2005) 48:420-437.
    • (2005) Brain Res. Brain Res. Rev , vol.48 , pp. 420-437
    • WANG, H.1    SUN, X.2
  • 37
    • 0034595443 scopus 로고    scopus 로고
    • Inactivation of α7 ACh receptors and activation of non-α7 ACh receptors both contribute to long term potentiation induction in the hippocampal CA1 region
    • FUJII S, JI Z, SUMIKAWA K: Inactivation of α7 ACh receptors and activation of non-α7 ACh receptors both contribute to long term potentiation induction in the hippocampal CA1 region. Neurosci. Lett. (2000) 286:134-138.
    • (2000) Neurosci. Lett , vol.286 , pp. 134-138
    • FUJII, S.1    JI, Z.2    SUMIKAWA, K.3
  • 38
    • 0034879826 scopus 로고    scopus 로고
    • Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity
    • JI D, LAPE R, DANI JA. Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron (2001) 31:131-141.
    • (2001) Neuron , vol.31 , pp. 131-141
    • JI, D.1    LAPE, R.2    DANI, J.A.3
  • 39
    • 0031667995 scopus 로고    scopus 로고
    • The cholinergic deficit in Alzheimer s disease
    • WHITEHOUSE PJ: The cholinergic deficit in Alzheimer s disease. J. Clin. Psychiat. (1998) 59:19-22.
    • (1998) J. Clin. Psychiat , vol.59 , pp. 19-22
    • WHITEHOUSE, P.J.1
  • 40
    • 0742288775 scopus 로고    scopus 로고
    • Effects of nicotinic stimulation on cognitive performance
    • NEWHOUSE PA, POTTER A, SINGH A. Effects of nicotinic stimulation on cognitive performance. Curr. Opin. Pharmacol. (2004) 4:36-46.
    • (2004) Curr. Opin. Pharmacol , vol.4 , pp. 36-46
    • NEWHOUSE, P.A.1    POTTER, A.2    SINGH, A.3
  • 41
    • 10844237451 scopus 로고    scopus 로고
    • Nicotinic receptor mechanisms and cognition in normal states and neuropsychiatric disorders
    • SACCO KA, BANNON KL, GEORGE TP: Nicotinic receptor mechanisms and cognition in normal states and neuropsychiatric disorders. J. Psychopharm. (2004) 18:457-474.
    • (2004) J. Psychopharm , vol.18 , pp. 457-474
    • SACCO, K.A.1    BANNON, K.L.2    GEORGE, T.P.3
  • 42
    • 0032971370 scopus 로고    scopus 로고
    • Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: Histotopographical correlation with amyloid plaques and hyperphosphorylaed-tau protein
    • WEVERS A, MONTEGGIA L, NOWACKI S et al.: Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: histotopographical correlation with amyloid plaques and hyperphosphorylaed-tau protein. Eur. J. Aeurosci. (1999) 11:2551-2565.
    • (1999) Eur. J. Aeurosci , vol.11 , pp. 2551-2565
    • WEVERS, A.1    MONTEGGIA, L.2    NOWACKI, S.3
  • 43
    • 0037066072 scopus 로고    scopus 로고
    • WANG H-Y: Intraneuronal accumulation of β-amyloid 1-42 is mediated by the α7 nicotinic acetylcholine receptor in Alzheimer s disease
    • NAGELE RG, D'ANDREA MR, WANG H-Y: intraneuronal accumulation of β-amyloid 1-42 is mediated by the α7 nicotinic acetylcholine receptor in Alzheimer s disease. Neuroscience (2002) 110:199-211.
    • (2002) Neuroscience , vol.110 , pp. 199-211
    • NAGELE, R.G.1    D'ANDREA, M.R.2
  • 44
    • 33645319504 scopus 로고    scopus 로고
    • ANDREA MR, NAGELE RG: Targeting the α7 ncitonic acetylcholine receptor to reduce amyloid accumulation in Alzheimer s disease pyramidal neurons
    • D
    • D ANDREA MR, NAGELE RG: Targeting the α7 ncitonic acetylcholine receptor to reduce amyloid accumulation in Alzheimer s disease pyramidal neurons. Curr. Pharmaceut. Des. (2006) 12:677-684.
    • (2006) Curr. Pharmaceut. Des , vol.12 , pp. 677-684
  • 45
    • 4444222165 scopus 로고    scopus 로고
    • WU J, KUO Y-P, GEORGE AA, XU L, HU J, LUKAS RJ: β-Amyloid directly inhibits human α4β2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells. J. Biol. Chem. (2004) 279:37842-37851.
    • WU J, KUO Y-P, GEORGE AA, XU L, HU J, LUKAS RJ: β-Amyloid directly inhibits human α4β2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells. J. Biol. Chem. (2004) 279:37842-37851.
  • 46
    • 0036316642 scopus 로고    scopus 로고
    • Chronic nicotine treatment reduces β-amyloidosis in the brain of a mouse model of Alzheimer s disease (APPsw)
    • NORDBERG A, HELLSTROM-LINDAHL E, LEE M et al.: Chronic nicotine treatment reduces β-amyloidosis in the brain of a mouse model of Alzheimer s disease (APPsw). J. Neurochem. (2002) 81:655-658.
    • (2002) J. Neurochem , vol.81 , pp. 655-658
    • NORDBERG, A.1    HELLSTROM-LINDAHL, E.2    LEE, M.3
  • 47
    • 31144450053 scopus 로고    scopus 로고
    • Current pharmacotherapy for Alzheimer's disease
    • LLEO A, GREENBERG SM, GROWDON JH: Current pharmacotherapy for Alzheimer's disease. Annu. Rev. Med. (2006) 57:513-533.
    • (2006) Annu. Rev. Med , vol.57 , pp. 513-533
    • LLEO, A.1    GREENBERG, S.M.2    GROWDON, J.H.3
  • 49
    • 33847137816 scopus 로고    scopus 로고
    • Effect of ispronicline, a neuronal nicotinic acetylcholine receptor partial agonist, in subjects with age associated memory impairment (AAMI)
    • DUNBAR GC, INGLIS F, KUCHIBHATLA R, SHARMA T, TOMLINSON M, WAMSLEY J: Effect of ispronicline, a neuronal nicotinic acetylcholine receptor partial agonist, in subjects with age associated memory impairment (AAMI). J. Psychopharmacol. (2007) 21:171-178.
    • (2007) J. Psychopharmacol , vol.21 , pp. 171-178
    • DUNBAR, G.C.1    INGLIS, F.2    KUCHIBHATLA, R.3    SHARMA, T.4    TOMLINSON, M.5    WAMSLEY, J.6
  • 50
    • 2942598335 scopus 로고    scopus 로고
    • Nicotine reduces A β in the brain and cerebral vessels of APPsw mice
    • HELLSTROM-LINDAHL E, COURT J, KEVERNE J et al.: Nicotine reduces A β in the brain and cerebral vessels of APPsw mice. Eur. J. Neurosci. (2004) 19:2703-2710.
    • (2004) Eur. J. Neurosci , vol.19 , pp. 2703-2710
    • HELLSTROM-LINDAHL, E.1    COURT, J.2    KEVERNE, J.3
  • 51
    • 0042155870 scopus 로고    scopus 로고
    • Cigarette smoke and nicotine protect dopaminergic neurons against the 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine Parkinsonian toxin
    • PARAIN K, HAPDEY C, ROUSSELET E, MARCHAND V, DUMERY B, HIRSCH EC: Cigarette smoke and nicotine protect dopaminergic neurons against the 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine Parkinsonian toxin. Brain Res. (2003) 984:224-232.
    • (2003) Brain Res , vol.984 , pp. 224-232
    • PARAIN, K.1    HAPDEY, C.2    ROUSSELET, E.3    MARCHAND, V.4    DUMERY, B.5    HIRSCH, E.C.6
  • 52
    • 0037622682 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons
    • TAKADA Y, YONEZAWA A, KUME T et al.: Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons. J. Pharmacol. Exp. Ther. (2003) 306:772-777.
    • (2003) J. Pharmacol. Exp. Ther , vol.306 , pp. 772-777
    • TAKADA, Y.1    YONEZAWA, A.2    KUME, T.3
  • 53
    • 0011359002 scopus 로고    scopus 로고
    • The role of neuronal nicotinic acetylcholine receptors in acute and chronic neurodegeneration
    • O NEILL MJ, MURRAY TK, LAKICS V, VISANJI NP, DUTY S: The role of neuronal nicotinic acetylcholine receptors in acute and chronic neurodegeneration. Curr. Drug Targets CNS Neurol. Disord. (2002) 1:399-411.
    • (2002) Curr. Drug Targets CNS Neurol. Disord , vol.1 , pp. 399-411
    • NEILL, O.1    MJ, M.T.2    LAKICS, V.3    VISANJI, N.P.4    DUTY, S.5
  • 54
    • 34848923606 scopus 로고    scopus 로고
    • FLORES CM, HARGREAVES KM: Neuronal nicotinic receptors: new targets in the treatment of pain. In: Neuronal Nicotinic Receptors: Phamacology and Therapeutic Opportunities. Arneric SR Brioni JD (Eds), Wiley-Liss, New York, USA (1998):3 59-378.
    • FLORES CM, HARGREAVES KM: Neuronal nicotinic receptors: new targets in the treatment of pain. In: Neuronal Nicotinic Receptors: Phamacology and Therapeutic Opportunities. Arneric SR Brioni JD (Eds), Wiley-Liss, New York, USA (1998):3 59-378.
  • 55
    • 0035956945 scopus 로고    scopus 로고
    • Tonic nicotinic modulation of serotonergic transmission in the spinal cord
    • CORDERO-ERAUSQUIN M, CHANGEUX JP: Tonic nicotinic modulation of serotonergic transmission in the spinal cord. Proc. Natl. Acad. Sci. USA (2001) 98:2803-2807.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2803-2807
    • CORDERO-ERAUSQUIN, M.1    CHANGEUX, J.P.2
  • 56
    • 0034725791 scopus 로고    scopus 로고
    • Spinal mechanisms underlying A-85380-induced cflects on acute thermal pain
    • RUETER LE, MEYER MD, DECKER MW: Spinal mechanisms underlying A-85380-induced cflects on acute thermal pain. Brain Res. (2000) 872:93-101.
    • (2000) Brain Res , vol.872 , pp. 93-101
    • RUETER, L.E.1    MEYER, M.D.2    DECKER, M.W.3
  • 57
    • 0034307124 scopus 로고    scopus 로고
    • The promise and pitfalls of a nicotinic cholinergic approach to pain management
    • FLORES CM: The promise and pitfalls of a nicotinic cholinergic approach to pain management. Pain (2000) 88:1-6.
    • (2000) Pain , vol.88 , pp. 1-6
    • FLORES, C.M.1
  • 58
    • 0028886560 scopus 로고
    • Different methods of assessing nicotinc-induced antinociception may engage different neural mechanisms
    • CAGGIULA AR, EPSTEIN LH, PERKINS KA, SAYLOR S: Different methods of assessing nicotinc-induced antinociception may engage different neural mechanisms. Psychopharmacology (1995) 122:301-306.
    • (1995) Psychopharmacology , vol.122 , pp. 301-306
    • CAGGIULA, A.R.1    EPSTEIN, L.H.2    PERKINS, K.A.3    SAYLOR, S.4
  • 59
    • 15144343497 scopus 로고    scopus 로고
    • Broad spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors
    • BANNON AW, DECKER MW, HOLLADAY MW et al.: Broad spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors. Science (1998) 279:77-81.
    • (1998) Science , vol.279 , pp. 77-81
    • BANNON, A.W.1    DECKER, M.W.2    HOLLADAY, M.W.3
  • 60
    • 26844476004 scopus 로고    scopus 로고
    • α-conotoxin Vc 1.1 alleviates neuropathic pain and accelerates functional recovery of injured neurons
    • SATKUNANATHAN N, LIVETT B, GAYLER K, SANDALL K, DOWN J, KHALIL Z: α-conotoxin Vc 1.1 alleviates neuropathic pain and accelerates functional recovery of injured neurons. Brain Res. (2005) 1059:149-158.
    • (2005) Brain Res , vol.1059 , pp. 149-158
    • SATKUNANATHAN, N.1    LIVETT, B.2    GAYLER, K.3    SANDALL, K.4    DOWN, J.5    KHALIL, Z.6
  • 61
    • 11844291367 scopus 로고    scopus 로고
    • Nicotinic modulation of GABAergic synaptic transmission in the spinal cord dorsal horn
    • GENZEN J, D MCGEHEE: Nicotinic modulation of GABAergic synaptic transmission in the spinal cord dorsal horn. Brain Res. (2005) 1031:229-237.
    • (2005) Brain Res , vol.1031 , pp. 229-237
    • GENZEN, J.1    MCGEHEE, D.2
  • 62
    • 1642340652 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor agonists: A potential new class of analgesics
    • DECKER MW, RUETER LE, BITNER RS: Nicotinic acetylcholine receptor agonists: a potential new class of analgesics. Curr. Top. Med. Chem. (2004) 4:369-384.
    • (2004) Curr. Top. Med. Chem , vol.4 , pp. 369-384
    • DECKER, M.W.1    RUETER, L.E.2    BITNER, R.S.3
  • 63
    • 0034648041 scopus 로고    scopus 로고
    • Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat
    • BITNER RS, NIKKEL Al, CURZON P et al.: Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat. Brain Res. (2000) 871:66-74.
    • (2000) Brain Res , vol.871 , pp. 66-74
    • BITNER, R.S.1    NIKKEL, A.2    CURZON, P.3
  • 64
    • 0142091438 scopus 로고    scopus 로고
    • Hypersensitive knock-in mouse strains identify receptors and pathways for nicotine action
    • LESTER HA, FONCK C, TAPPER AR et al.: Hypersensitive knock-in mouse strains identify receptors and pathways for nicotine action. Curr. Opin. Drug Dis. Dev. (2003) 6:633-639.
    • (2003) Curr. Opin. Drug Dis. Dev , vol.6 , pp. 633-639
    • LESTER, H.A.1    FONCK, C.2    TAPPER, A.R.3
  • 65
    • 13444259736 scopus 로고    scopus 로고
    • Improving the therapeutic window in the treatment of pain with nicotinic ligands
    • RUETER LE, DECKER MW, BITNER RS: Improving the therapeutic window in the treatment of pain with nicotinic ligands. Drug Disc. Today Ther. Strat. (2004) 1:89-96.
    • (2004) Drug Disc. Today Ther. Strat , vol.1 , pp. 89-96
    • RUETER, L.E.1    DECKER, M.W.2    BITNER, R.S.3
  • 66
    • 0347301636 scopus 로고    scopus 로고
    • Plasticity of spinal nicotinic acetylcholine receptors following spinal nerve ligation
    • VINCLER MA, EISENACH JC: Plasticity of spinal nicotinic acetylcholine receptors following spinal nerve ligation. Neurosci. Res. (2004) 48:139-145.
    • (2004) Neurosci. Res , vol.48 , pp. 139-145
    • VINCLER, M.A.1    EISENACH, J.C.2
  • 67
    • 12344297870 scopus 로고    scopus 로고
    • Knock down of the α nicotinic acetylcholine receptor in spinal nerve-ligated rats alleviates mechanical allodynia
    • VINCLER MA, EISENACH JC: Knock down of the α nicotinic acetylcholine receptor in spinal nerve-ligated rats alleviates mechanical allodynia. Pharmacol. Biochem. Behav. (2005) 80:135-143.
    • (2005) Pharmacol. Biochem. Behav , vol.80 , pp. 135-143
    • VINCLER, M.A.1    EISENACH, J.C.2
  • 68
    • 0029670191 scopus 로고    scopus 로고
    • Functional contributions of α5 subunit to neuronal acetylcholine receptor channels
    • RAMIREZ-LATORRE J, YU CR, QU X, PERIN F, KARLIN A, ROLE L: Functional contributions of α5 subunit to neuronal acetylcholine receptor channels. Nature (1996) 380:347-351.
    • (1996) Nature , vol.380 , pp. 347-351
    • RAMIREZ-LATORRE, J.1    YU, C.R.2    QU, X.3    PERIN, F.4    KARLIN, A.5    ROLE, L.6
  • 69
    • 0033626562 scopus 로고    scopus 로고
    • The antinociceptive effects of α7 nicotinic agonists in an acute pain model
    • DAMAJ MI, MEYER EM, MARTIN BR: The antinociceptive effects of α7 nicotinic agonists in an acute pain model. Neurophamacology (2000) 39:2785-2791.
    • (2000) Neurophamacology , vol.39 , pp. 2785-2791
    • DAMAJ, M.I.1    MEYER, E.M.2    MARTIN, B.R.3
  • 70
    • 15044360252 scopus 로고    scopus 로고
    • Antinociceptive effects of choline against acute and inflammatory pain
    • WANG Y, SU DM, WANG RH, LIU Y, WANG H: Antinociceptive effects of choline against acute and inflammatory pain. Neuroscience (2005) 132:49-56.
    • (2005) Neuroscience , vol.132 , pp. 49-56
    • WANG, Y.1    SU, D.M.2    WANG, R.H.3    LIU, Y.4    WANG, H.5
  • 71
    • 34848819068 scopus 로고    scopus 로고
    • Antinociceptive effect of nicotine on tibial nerve transection-induced neuropathic pain
    • MORIOKA N, ABJIN J, MORITA K et al.: Antinociceptive effect of nicotine on tibial nerve transection-induced neuropathic pain. Soc. Neurosci. Abstr. (2006) 803:13.
    • (2006) Soc. Neurosci. Abstr , vol.803 , pp. 13
    • MORIOKA, N.1    ABJIN, J.2    MORITA, K.3
  • 72
    • 34848902277 scopus 로고    scopus 로고
    • Involvement of α7 nicotinic receptors in acute and chronic pain transmission
    • DAMAJ MI, MARUBIO L, MARTIN BR: Involvement of α7 nicotinic receptors in acute and chronic pain transmission. Soc. Neurosci. Abstr. (2003) 693:12.
    • (2003) Soc. Neurosci. Abstr , vol.693 , pp. 12
    • DAMAJ, M.I.1    MARUBIO, L.2    MARTIN, B.R.3
  • 73
    • 23844454674 scopus 로고    scopus 로고
    • DE JONGE WJ, VAN DER ZANDEN EP, THE FO et al.: Stimulation of the vagus nerve attenuates macrophage activation by activating the JAK2-STAT3 signaling pathway. Nat. Immunol. (2005) 6:844-851.
    • DE JONGE WJ, VAN DER ZANDEN EP, THE FO et al.: Stimulation of the vagus nerve attenuates macrophage activation by activating the JAK2-STAT3 signaling pathway. Nat. Immunol. (2005) 6:844-851.
  • 74
    • 33646522174 scopus 로고    scopus 로고
    • The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice
    • VAN WESTERLOO DJ, GIEBELEN IA, FLORQUIN S et al: The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice. Gastroenterology (2006) 130:1822-1830.
    • (2006) Gastroenterology , vol.130 , pp. 1822-1830
    • VAN WESTERLOO, D.J.1    GIEBELEN, I.A.2    FLORQUIN, S.3
  • 75
  • 76
    • 33747372837 scopus 로고    scopus 로고
    • The synthesis, tructural characterization, and receptor pecificity of the α-conotoxin Vc1.1
    • CLARK RJ, FISCHER H, NEVIN ST, ADAMS DJ, CRAIK DJ:The synthesis, tructural characterization, and receptor pecificity of the α-conotoxin Vc1.1. J. Biol. Chem. (2006) 281:23254-23263.
    • (2006) J. Biol. Chem , vol.281 , pp. 23254-23263
    • CLARK, R.J.1    FISCHER, H.2    NEVIN, S.T.3    ADAMS, D.J.4    CRAIK, D.J.5
  • 77
    • 32244443936 scopus 로고    scopus 로고
    • α-RgIA: A novel conotoxin that specifically and potently blocks the α9α10 nAChR
    • ELLISON M, HABERLANDT C, GOMEZ-CASATI ME et al.: α-RgIA: a novel conotoxin that specifically and potently blocks the α9α10 nAChR. Biochemitry (2006) 45:1511-1517.
    • (2006) Biochemitry , vol.45 , pp. 1511-1517
    • ELLISON, M.1    HABERLANDT, C.2    GOMEZ-CASATI, M.E.3
  • 78
    • 0037110652 scopus 로고    scopus 로고
    • Coexpression of α9 and α10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons
    • LIPS KS, PFEIL U, KUMMER W: Coexpression of α9 and α10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons. Neuroscience (2002) 15:1-5.
    • (2002) Neuroscience , vol.15 , pp. 1-5
    • LIPS, K.S.1    PFEIL, U.2    KUMMER, W.3
  • 79
    • 7544225904 scopus 로고    scopus 로고
    • Characterization of the human nicotinic acetylcholine receptor subunit α (alpha) 9 (CHRNA9) and α (alpha) 10 (CHRNA10) in lymphocytes
    • PENG H, FERRIS RL, MATMEWS T, HIEL H, LOPEZ-ALBAITERO A, LUSTIG LR: Characterization of the human nicotinic acetylcholine receptor subunit α (alpha) 9 (CHRNA9) and α (alpha) 10 (CHRNA10) in lymphocytes. Life Sci. (2004) 76:263-280.
    • (2004) Life Sci , vol.76 , pp. 263-280
    • PENG, H.1    FERRIS, R.L.2    MATMEWS, T.3    HIEL, H.4    LOPEZ-ALBAITERO, A.5    LUSTIG, L.R.6
  • 80
    • 2342439356 scopus 로고    scopus 로고
    • Modulators of nicotinic acetylcholine receptors as analgesics
    • JAIN KK. Modulators of nicotinic acetylcholine receptors as analgesics. Curr. Opin. Investig. Drugs (2004) 5:76-81.
    • (2004) Curr. Opin. Investig. Drugs , vol.5 , pp. 76-81
    • JAIN, K.K.1
  • 81
  • 83
    • 0032032904 scopus 로고    scopus 로고
    • Anddepressant-like effects of chronic nicotine on learned helplessness paradigm in rats
    • SEMBA J, MATAKI C, YAMADA S, NANKAI M, TORU M: Anddepressant-like effects of chronic nicotine on learned helplessness paradigm in rats. Biol. Psychiatry (1998) 43:389-391.
    • (1998) Biol. Psychiatry , vol.43 , pp. 389-391
    • SEMBA, J.1    MATAKI, C.2    YAMADA, S.3    NANKAI, M.4    TORU, M.5
  • 84
    • 2442690113 scopus 로고    scopus 로고
    • Antidepressant-like effects of the acute and chronic administration of nicotine in the rat forced swimming test and its interaction with fluoxetine
    • VAZQUEZ-PALACIOS G, BONILLA-JAIME H, VELAZQUEZ-MOCTEZUMA J: Antidepressant-like effects of the acute and chronic administration of nicotine in the rat forced swimming test and its interaction with fluoxetine. Pharmacol. Biochem. Behav. (2004) 78:165-169.
    • (2004) Pharmacol. Biochem. Behav , vol.78 , pp. 165-169
    • VAZQUEZ-PALACIOS, G.1    BONILLA-JAIME, H.2    VELAZQUEZ-MOCTEZUMA, J.3
  • 85
    • 0032955920 scopus 로고    scopus 로고
    • Antidepressant effects of nicotine in an animal model of depression
    • TIZABI Y, OVERSTREET DH, REZVANI AH et al.: Antidepressant effects of nicotine in an animal model of depression. Pychopharmacology (Berl.) (1999) 142:193-199.
    • (1999) Pychopharmacology (Berl.) , vol.142 , pp. 193-199
    • TIZABI, Y.1    OVERSTREET, D.H.2    REZVANI, A.H.3
  • 86
    • 0029780031 scopus 로고    scopus 로고
    • SALIN-PASCUAL RJ, ROSAS M, JIMENEZ-GENCHI A, R]VERA-MEZA BL, DELGADO-PARRA V: Antidepressant effect of transdermal nicotine patches in nonsmoking patients with major depression. J. Clin. Pychiatry (1996) 57:387-389.
    • SALIN-PASCUAL RJ, ROSAS M, JIMENEZ-GENCHI A, R]VERA-MEZA BL, DELGADO-PARRA V: Antidepressant effect of transdermal nicotine patches in nonsmoking patients with major depression. J. Clin. Pychiatry (1996) 57:387-389.
  • 88
    • 0032934644 scopus 로고    scopus 로고
    • Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine
    • FRYER JD, LUKAS RJ: Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine. J. Pharmacol. Exp. Ther. (1999) 288:88-92.
    • (1999) J. Pharmacol. Exp. Ther , vol.288 , pp. 88-92
    • FRYER, J.D.1    LUKAS, R.J.2
  • 89
    • 33751092270 scopus 로고    scopus 로고
    • The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not β2- or α7-nicotinic acetylcholine receptor subunit knockout mice
    • RABENSTEIN RL, CALDARONE BJ, PICCIOTTO MR: The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not β2- or α7-nicotinic acetylcholine receptor subunit knockout mice. Pychopharmacology (Berl.) (2006) 189:395-401.
    • (2006) Pychopharmacology (Berl.) , vol.189 , pp. 395-401
    • RABENSTEIN, R.L.1    CALDARONE, B.J.2    PICCIOTTO, M.R.3
  • 92
    • 7444253542 scopus 로고    scopus 로고
    • High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation
    • CALDARONE BJ, HARRIST A, CLEARY MA, BEECH RD, KING SL, PICCIOTTO MR: High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation. Biol. Psychiatry (2004) 56:657-664.
    • (2004) Biol. Psychiatry , vol.56 , pp. 657-664
    • CALDARONE, B.J.1    HARRIST, A.2    CLEARY, M.A.3    BEECH, R.D.4    KING, S.L.5    PICCIOTTO, M.R.6
  • 93
    • 0035956994 scopus 로고    scopus 로고
    • Point mutant mice with hypersensitive α4 nicotinic receptors show doparninergic deficits and increased anxiety
    • LABARCA C, SCHWARZ J, DESHPANDE P et al.: Point mutant mice with hypersensitive α4 nicotinic receptors show doparninergic deficits and increased anxiety. Proc. Natl. Acad. Sci. USA (2001) 98:2786-2791.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2786-2791
    • LABARCA, C.1    SCHWARZ, J.2    DESHPANDE, P.3
  • 94
    • 34047183628 scopus 로고    scopus 로고
    • Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice
    • Epub ahead of print
    • MINEUR YS, SOMENZI O, PICCIOTTO MR: Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice. Neuropharmacology (2007) [Epub ahead of print].
    • (2007) Neuropharmacology
    • MINEUR, Y.S.1    SOMENZI, O.2    PICCIOTTO, M.R.3
  • 95
    • 0037870490 scopus 로고    scopus 로고
    • Schizophrenia: From phenomenology to neurobiology
    • WONG AHC, VAN TOL HHM: Schizophrenia: from phenomenology to neurobiology. Neurosci. Biobehav. Rev. (2003) 27:269-306.
    • (2003) Neurosci. Biobehav. Rev , vol.27 , pp. 269-306
    • AHC, W.O.N.G.1    HHM, V.T.2
  • 97
    • 0029085870 scopus 로고
    • Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia
    • FREEDMAN F, HALL M, ADLER LE, LEONARD S: Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biol. Psychiatry (1995) 38:22-33.
    • (1995) Biol. Psychiatry , vol.38 , pp. 22-33
    • FREEDMAN, F.1    HALL, M.2    ADLER, L.E.3    LEONARD, S.4
  • 98
    • 0033519564 scopus 로고    scopus 로고
    • Decreased protein level of nicotinic acetylcholine receptor α7 subunit in the frontal cortex from schizophrenic brain
    • GUAN ZZ, ZHANGX, BLENNW K et al.: Decreased protein level of nicotinic acetylcholine receptor α7 subunit in the frontal cortex from schizophrenic brain. Neuroreport (1999) 10:1779-1782.
    • (1999) Neuroreport , vol.10 , pp. 1779-1782
    • GUAN, Z.Z.1
  • 99
    • 0030884260 scopus 로고    scopus 로고
    • Comparison of the regional expression of nicotinic acetylcholine receptor α7 mRNA and [I 25I]-α-bungarotoxin binding in human postmortem brain
    • BREESE CR, ADAMS C, LOGEL J et al.: Comparison of the regional expression of nicotinic acetylcholine receptor α7 mRNA and [I 25I]-α-bungarotoxin binding in human postmortem brain. J. Comp. Neurol. (1997) 387:385-398.
    • (1997) J. Comp. Neurol , vol.387 , pp. 385-398
    • BREESE, C.R.1    ADAMS, C.2    LOGEL, J.3
  • 100
    • 0033709986 scopus 로고    scopus 로고
    • Long-term potentiation of excitatory inputs to brain reward area by nicotine
    • MANSVELDER HD, MCGEHEE DS: Long-term potentiation of excitatory inputs to brain reward area by nicotine. Neuron (2000) 27:349-357.
    • (2000) Neuron , vol.27 , pp. 349-357
    • MANSVELDER, H.D.1    MCGEHEE, D.S.2
  • 101
    • 33947303210 scopus 로고    scopus 로고
    • Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in α nicotinic receptor knockout mice
    • EGEA J, ROSA AO, SOBRADO M, GANDIA L, LOPEZ MG, GARCIA AG: Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in α nicotinic receptor knockout mice. Neuroscience (2007) 145:866-872.
    • (2007) Neuroscience , vol.145 , pp. 866-872
    • EGEA, J.1    ROSA, A.O.2    SOBRADO, M.3    GANDIA, L.4    LOPEZ, M.G.5    GARCIA, A.G.6
  • 102
    • 33745824638 scopus 로고    scopus 로고
    • Genetics of chromosome 15q13-q14 in schizophrenia
    • LEONARD S, FREEDMAN R: Genetics of chromosome 15q13-q14 in schizophrenia. Biol. Psychiatry (2006) 60:115-122.
    • (2006) Biol. Psychiatry , vol.60 , pp. 115-122
    • LEONARD, S.1    FREEDMAN, R.2
  • 104
    • 0141889787 scopus 로고    scopus 로고
    • Breaking the log-jam in treatment development for cognition in schizophrenia: NIMH perspective
    • FENTON WS, STOVER EL, INSEL TR: Breaking the log-jam in treatment development for cognition in schizophrenia: NIMH perspective. Psychopharmacology (2003) 169:365-366.
    • (2003) Psychopharmacology , vol.169 , pp. 365-366
    • FENTON, W.S.1    STOVER, E.L.2    INSEL, T.R.3
  • 106
    • 0028934741 scopus 로고
    • Improved learning and memory in aged rats with chronic administration of nicotinic receptor agonist GTS-21
    • ARENDASH GW, SENGSTOCK GJ, SANBERG PR, KEM WR: Improved learning and memory in aged rats with chronic administration of nicotinic receptor agonist GTS-21. Brain Res. (1995) 674:252-259.
    • (1995) Brain Res , vol.674 , pp. 252-259
    • ARENDASH, G.W.1    SENGSTOCK, G.J.2    SANBERG, P.R.3    KEM, W.R.4
  • 107
    • 0028341821 scopus 로고
    • Nicotinic cholinergic system involvement in eyeblink classical conditioning in rabbits
    • WOODRUFF-PAK DS, LI YT; KAZMI A, KEM WR: Nicotinic cholinergic system involvement in eyeblink classical conditioning in rabbits. Behav. Neurosci. (1994) 108:486-493.
    • (1994) Behav. Neurosci , vol.108 , pp. 486-493
    • WOODRUFF-PAK, D.S.1    LI, Y.T.2    KAZMI, A.3    KEM, W.R.4
  • 108
    • 0031003185 scopus 로고    scopus 로고
    • Functional characterization of a novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo
    • BRIGGS CA, ANDERSON DJ, BRIONI JD et al.: Functional characterization of a novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo. Pharmacol. Biochem. Behav. (1997) 57:231-241.
    • (1997) Pharmacol. Biochem. Behav , vol.57 , pp. 231-241
    • BRIGGS, C.A.1    ANDERSON, D.J.2    BRIONI, J.D.3
  • 109
    • 0035470834 scopus 로고    scopus 로고
    • Intragastric DMXB-A, an α7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice
    • SIMOSKY JK, STEVENS KE, KEM WR, FREEDMAN R: Intragastric DMXB-A, an α7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice. Biol. Psychiatry (2001) 50:493-500.
    • (2001) Biol. Psychiatry , vol.50 , pp. 493-500
    • SIMOSKY, J.K.1    STEVENS, K.E.2    KEM, W.R.3    FREEDMAN, R.4
  • 110
    • 20944441082 scopus 로고    scopus 로고
    • A novel positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor: In vitro and in vivo characterization
    • HURST RS, HAJOS M, RAGGENBASS M et. al.: A novel positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. J. Neurosci. (2005) 25:4396-4405.
    • (2005) J. Neurosci , vol.25 , pp. 4396-4405
    • HURST, R.S.1    HAJOS, M.2    RAGGENBASS, M.3    et., al.4
  • 111
    • 14344251489 scopus 로고    scopus 로고
    • The selective α7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain shoes and restores auditory gating deficits in anesthetized rats
    • HAJ S M, HURST RS, HOFFMANN WE et al.: The selective α7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain shoes and restores auditory gating deficits in anesthetized rats. JPET (2005) 312:1213-1222.
    • (2005) JPET , vol.312 , pp. 1213-1222
    • HAJ, S.M.1    HURST, R.S.2    HOFFMANN, W.E.3
  • 112
    • 0035708467 scopus 로고    scopus 로고
    • Ventral hippocampal α7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze
    • BETTANY JH, LEVIN ED: Ventral hippocampal α7 nicotinic receptor blockade and chronic nicotine effects on memory performance in the radial-arm maze. Pharmacol. Biochem. Behav. (2001) 70:467-474.
    • (2001) Pharmacol. Biochem. Behav , vol.70 , pp. 467-474
    • BETTANY, J.H.1    LEVIN, E.D.2
  • 113
    • 0037362990 scopus 로고    scopus 로고
    • Nicotinic mechanisms of memory: Effects of acute local DhPE and MLA infusions in the basolateral amygdala
    • ADDY NA, NAKIJAMA A, LEVIN ED: Nicotinic mechanisms of memory: effects of acute local DhPE and MLA infusions in the basolateral amygdala. Brain Res. Cogn. Brain Res. (2003) 16:51-57.
    • (2003) Brain Res. Cogn. Brain Res , vol.16 , pp. 51-57
    • ADDY, N.A.1    NAKIJAMA, A.2    LEVIN, E.D.3
  • 114
    • 0031751031 scopus 로고    scopus 로고
    • Schizophrenia, sensory gating and nicotinic receptors
    • ADLER LE, OLINCY A, WALDO MC et al.: Schizophrenia, sensory gating and nicotinic receptors. Schizophr. Bull. (1998) 24:189-202.
    • (1998) Schizophr. Bull , vol.24 , pp. 189-202
    • ADLER, L.E.1    OLINCY, A.2    WALDO, M.C.3
  • 115
    • 0032532749 scopus 로고    scopus 로고
    • Anticipatory saccades during smooth pursuit eye movements and familial transmission of schizophrenia
    • ROSS RG, OLINCY A, HARRIS JG et al.: Anticipatory saccades during smooth pursuit eye movements and familial transmission of schizophrenia. Biol. Psychiatry (1998) 44:690-697.
    • (1998) Biol. Psychiatry , vol.44 , pp. 690-697
    • ROSS, R.G.1    OLINCY, A.2    HARRIS, J.G.3
  • 116
    • 26844530147 scopus 로고    scopus 로고
    • Reversal of isolarion-rearing-induced PPI deficits by an α7 nicotinic receptor agonist
    • CILIA J, CLUDERAY JE, ROBBINS MJ et al.: Reversal of isolarion-rearing-induced PPI deficits by an α7 nicotinic receptor agonist. Pychopharmacology (2005) 182:214-219.
    • (2005) Pychopharmacology , vol.182 , pp. 214-219
    • CILIA, J.1    CLUDERAY, J.E.2    ROBBINS, M.J.3
  • 118
    • 0033237390 scopus 로고    scopus 로고
    • AR-R 17779, an 2a7 nicotinic agonist, improves learning and memory in rats
    • LEVIN ED, BETTEGOWDA C, BLOSSER J, GORDON J: AR-R 17779, an 2a7 nicotinic agonist, improves learning and memory in rats. Behav. Pharmacol. (1999) 10:675-680.
    • (1999) Behav. Pharmacol , vol.10 , pp. 675-680
    • LEVIN, E.D.1    BETTEGOWDA, C.2    BLOSSER, J.3    GORDON, J.4
  • 119
    • 34848872205 scopus 로고    scopus 로고
    • PICHAT P, BERGIS OE, TERRANOVAJP et al.: SSR180711A, a novel selective α7 nicotinic receptor partial agonist. III. Effects in models predictive of therapeutic activity on cognitive symptoms of schizophrenia. Soc. Neurosci. Abstr. (2004) 34:583.3.
    • PICHAT P, BERGIS OE, TERRANOVAJP et al.: SSR180711A, a novel selective α7 nicotinic receptor partial agonist. III. Effects in models predictive of therapeutic activity on cognitive symptoms of schizophrenia. Soc. Neurosci. Abstr. (2004) 34:583.3.
  • 120
    • 34848913113 scopus 로고    scopus 로고
    • BERGIS OE, PICHAT P, SANTAMARIA R et al.: SSR180711A, a novel selective α7 nicotinic receptor partial agonist. II. Effects in models predictive of therapeutic activity on cognitive symptoms of Alzheimer's disease. Soc. Neurosci. Abstr. (2004) 34:583.2.
    • BERGIS OE, PICHAT P, SANTAMARIA R et al.: SSR180711A, a novel selective α7 nicotinic receptor partial agonist. II. Effects in models predictive of therapeutic activity on cognitive symptoms of Alzheimer's disease. Soc. Neurosci. Abstr. (2004) 34:583.2.
  • 121
    • 33744911665 scopus 로고    scopus 로고
    • Proof-of-concept trial of an α7 nicotinic agonist in schizophrenia
    • OLINCY A, HARRIS JG, JOHNSON LL et al: Proof-of-concept trial of an α7 nicotinic agonist in schizophrenia. Arch. Gen. Psychiatry (2006) 63:630-638.
    • (2006) Arch. Gen. Psychiatry , vol.63 , pp. 630-638
    • OLINCY, A.1    HARRIS, J.G.2    JOHNSON, L.L.3
  • 122
    • 4344698859 scopus 로고    scopus 로고
    • Smoking, nicotine and Parkinson s disease
    • QUIK M: Smoking, nicotine and Parkinson s disease. Trends Neurosci. (2004) 27:561-568.
    • (2004) Trends Neurosci , vol.27 , pp. 561-568
    • QUIK, M.1
  • 124
    • 0029955936 scopus 로고    scopus 로고
    • Pharmacology of nicotine and its therapeutic use in smoking cessation and neurodegenerative disorders
    • BALFOUR DJ, FAGERSTROM KO: Pharmacology of nicotine and its therapeutic use in smoking cessation and neurodegenerative disorders. Pharmacol. Ther. (1996) 72:51-81.
    • (1996) Pharmacol. Ther , vol.72 , pp. 51-81
    • BALFOUR, D.J.1    FAGERSTROM, K.O.2
  • 125
    • 0031032949 scopus 로고    scopus 로고
    • Presynaptic nicotinic ACh receptors
    • WONNACOTT S: Presynaptic nicotinic ACh receptors. Trends Neurosci. (1997) 20:92-98. 127.
    • (1997) Trends Neurosci , vol.20 , Issue.92-98 , pp. 127
    • WONNACOTT, S.1
  • 126
    • 2442653986 scopus 로고    scopus 로고
    • Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice
    • SALMINEN O, MURPHY KL, MCINTOSH JM et al.: Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice. Mol. Pharmzacol. (2004) 65:1526-1535.
    • (2004) Mol. Pharmzacol , vol.65 , pp. 1526-1535
    • SALMINEN, O.1    MURPHY, K.L.2    MCINTOSH, J.M.3
  • 127
    • 0033587809 scopus 로고    scopus 로고
    • Involvement of a6 nicotinic receptor subunit in nicotine-eficited locomotion, demonstrated by in vivo antisense oligonucleotide infusion
    • LE NOVERE N, ZOLI M, LENA C et al.: Involvement of a6 nicotinic receptor subunit in nicotine-eficited locomotion, demonstrated by in vivo antisense oligonucleotide infusion. Neurareport (1999) 10:2497-2501.
    • (1999) Neurareport , vol.10 , pp. 2497-2501
    • LE NOVERE, N.1    ZOLI, M.2    LENA, C.3
  • 128
    • 2442657805 scopus 로고    scopus 로고
    • Getting past the asterisk: The subunit composition of presynaptic nicotinic receptors that modulate striatal dopamine release
    • LUETJE CW. Getting past the asterisk: the subunit composition of presynaptic nicotinic receptors that modulate striatal dopamine release. Mol. Pharmacol. (2004) 65:1333-1335.
    • (2004) Mol. Pharmacol , vol.65 , pp. 1333-1335
    • LUETJE, C.W.1
  • 129
    • 19944433294 scopus 로고    scopus 로고
    • Heterologous expression of human {a}6{β}4{β}3{α}5 nicotinic acetylcholine receptors: Binding properties consistent with their natural expression require quaternary subunit assembly including the {α}5 subunit
    • GRINEVICH VP, LETCHWORTH SR, LINDENBERGER KA et al.: Heterologous expression of human {a}6{β}4{β}3{α}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {α}5 subunit. J. Pharmacol. Exp. Ther. (2005) 312:619-626.
    • (2005) J. Pharmacol. Exp. Ther , vol.312 , pp. 619-626
    • GRINEVICH, V.P.1    LETCHWORTH, S.R.2    LINDENBERGER, K.A.3
  • 130
    • 0033930973 scopus 로고    scopus 로고
    • α-Bungarotoxin-sensitive nicotinic receptors indirectly modulate [(3)H]dopamine release in rat striatal slices via glutamate release
    • KAISER S, WONNACOTT S: α-Bungarotoxin-sensitive nicotinic receptors indirectly modulate [(3)H]dopamine release in rat striatal slices via glutamate release. Mol. Pharmacol. (2000) 58:312-318.
    • (2000) Mol. Pharmacol , vol.58 , pp. 312-318
    • KAISER, S.1    WONNACOTT, S.2
  • 131
    • 33746267516 scopus 로고    scopus 로고
    • Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation
    • GOTTI C, MORETTI M, BOHR I et al.: Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation. Neurobiol. Dis. (2006) 23:81-489.
    • (2006) Neurobiol. Dis , vol.23 , pp. 81-489
    • GOTTI, C.1    MORETTI, M.2    BOHR, I.3
  • 132
    • 0036144163 scopus 로고    scopus 로고
    • Loss of nicotinic receptors in monkey striatum. after 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine treatment is due to a decline in α-conotoxin MII sites
    • KULAK JM, MCINTOSH JM, QUIK M: Loss of nicotinic receptors in monkey striatum. after 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine treatment is due to a decline in α-conotoxin MII sites. Mol. Pharmacol. (2002) 61:230-238.
    • (2002) Mol. Pharmacol , vol.61 , pp. 230-238
    • KULAK, J.M.1    MCINTOSH, J.M.2    QUIK, M.3
  • 133
    • 0036204434 scopus 로고    scopus 로고
    • Presynaptic involvement in the nicotine prevention of the dopamine loss provoked by 6-OHDA administration in the substantia nigra
    • ABIN-CARRIQUIRY JA, MCGREGOR-ARMAS R, COSTA G, URBANAVICIUS J, DAJAS F: Presynaptic involvement in the nicotine prevention of the dopamine loss provoked by 6-OHDA administration in the substantia nigra. Neurvtox. Res. (2002) 4:133-139.
    • (2002) Neurvtox. Res , vol.4 , pp. 133-139
    • ABIN-CARRIQUIRY, J.A.1    MCGREGOR-ARMAS, R.2    COSTA, G.3    URBANAVICIUS, J.4    DAJAS, F.5
  • 134
    • 0032816456 scopus 로고    scopus 로고
    • Nicotine alone and in combination with L-DOPA methyl ester or the D(2) agonist N-0923 in MPTP-induced chronic hemiparkinsonian monkeys
    • DOMINO EF, NI L, ZHANG H: Nicotine alone and in combination with L-DOPA methyl ester or the D(2) agonist N-0923 in MPTP-induced chronic hemiparkinsonian monkeys. Exp. Neurol. (1999) 158:414-421.
    • (1999) Exp. Neurol , vol.158 , pp. 414-421
    • DOMINO, E.F.1    NI, L.2    ZHANG, H.3
  • 135
    • 0031826455 scopus 로고    scopus 로고
    • Effects of SIB-1508Y, a novel neuronal nicotinic acetylcholine receptor agonist, on motor behavior in parkinsonian monkeys
    • SCHNEIDER JS, POPE-COLEMAN A, VAN VELSON M, MENZAGHI F, LLOYD GK: Effects of SIB-1508Y, a novel neuronal nicotinic acetylcholine receptor agonist, on motor behavior in parkinsonian monkeys. Mov. Disord. (1998) 13:637-642.
    • (1998) Mov. Disord , vol.13 , pp. 637-642
    • SCHNEIDER, J.S.1    POPE-COLEMAN, A.2    VAN VELSON, M.3    MENZAGHI, F.4    LLOYD, G.K.5
  • 136
    • 0036890784 scopus 로고    scopus 로고
    • Nicotinic receptors in aging and dementia
    • PICCIOTTO MR, ZOLI M: Nicotinic receptors in aging and dementia. J. Neurobiol. (2002) 53:641-655.
    • (2002) J. Neurobiol , vol.53 , pp. 641-655
    • PICCIOTTO, M.R.1    ZOLI, M.2
  • 137
    • 0037185083 scopus 로고    scopus 로고
    • Stimulation of non-α7 nicotinic receptors partially protects dopaminergic neurons from 1-methyl-4-phenylpyridinium-induced toxicity in culture
    • JEYARASASINGAM G, TOMPKINS L, QUIK M: Stimulation of non-α7 nicotinic receptors partially protects dopaminergic neurons from 1-methyl-4-phenylpyridinium-induced toxicity in culture. Neuroscience (2002) 109:275-285.
    • (2002) Neuroscience , vol.109 , pp. 275-285
    • JEYARASASINGAM, G.1    TOMPKINS, L.2    QUIK, M.3
  • 138
    • 0023808881 scopus 로고
    • Chronic nicotine treatment counteracts the disappearance of tyrosine-hydroxylase-immunoreactive nerve cell bodies, dendrites and terminals in the mesostriaral doparnine system of the male rat after partial hernitransection
    • JANSON AM, FUXE Y, AGNATI LF et al.: Chronic nicotine treatment counteracts the disappearance of tyrosine-hydroxylase-immunoreactive nerve cell bodies, dendrites and terminals in the mesostriaral doparnine system of the male rat after partial hernitransection. Brain Res. (1988) 455:332-345.
    • (1988) Brain Res , vol.455 , pp. 332-345
    • JANSON, A.M.1    FUXE, Y.2    AGNATI, L.F.3
  • 139
    • 0025332639 scopus 로고
    • Chronic nicotine treatment increases dopamine levels and reduces doparnine utilization in substantia nigra and in surviving forebrain dopamine nerve terminal systems after a partial di-mesencephalic hemitransection
    • FUXE K, JANSON AM, JANSSON A, ANDERSSON K, ENEROTH P, AGNATI LF: Chronic nicotine treatment increases dopamine levels and reduces doparnine utilization in substantia nigra and in surviving forebrain dopamine nerve terminal systems after a partial di-mesencephalic hemitransection. Naunyn Schmiedebergs Arch. Pharmacol. (1990) 341:171-181.
    • (1990) Naunyn Schmiedebergs Arch. Pharmacol , vol.341 , pp. 171-181
    • FUXE, K.1    JANSON, A.M.2    JANSSON, A.3    ANDERSSON, K.4    ENEROTH, P.5    AGNATI, L.F.6
  • 140
    • 0035036071 scopus 로고    scopus 로고
    • Dose-related neuroprotective effects of chronic nicotine in 6-hydroxydopamine treated rats, and loss of neuroprorection in α4 nicotinic receptor subunit knockout mice
    • RYAN RE, ROSS SA, DRAGO J, LOIACONO RE: Dose-related neuroprotective effects of chronic nicotine in 6-hydroxydopamine treated rats, and loss of neuroprorection in α4 nicotinic receptor subunit knockout mice. Br. J. Pharmacol. (2001) 132:1650-1656.
    • (2001) Br. J. Pharmacol , vol.132 , pp. 1650-1656
    • RYAN, R.E.1    ROSS, S.A.2    DRAGO, J.3    LOIACONO, R.E.4
  • 141
    • 0035847204 scopus 로고    scopus 로고
    • Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the subscantia nigra
    • COSTA G,ABIN-CARRIQUIRY JA, DAJAS F: Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the subscantia nigra. Brain Res. (2001) 888:336-342.
    • (2001) Brain Res , vol.888 , pp. 336-342
    • COSTA, G.1    ABIN-CARRIQUIRY, J.A.2    DAJAS, F.3
  • 142
    • 33748159130 scopus 로고    scopus 로고
    • Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates
    • QUIX M, PARAMESWARAN N, MCCALLUM SE et al.: Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates. J. Neurochem. (2006) 98:1866-1875.
    • (2006) J. Neurochem , vol.98 , pp. 1866-1875
    • QUIX, M.1    PARAMESWARAN, N.2    MCCALLUM, S.E.3
  • 143
    • 33646823452 scopus 로고    scopus 로고
    • Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-lesioned primates
    • QUIK M, CHEN L, PARAMESWARAN N, XIE X, LANGSTON JW, MCCALLUM SE: Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-lesioned primates. J. Neurosci. (2006) 26:4681-4689.
    • (2006) J. Neurosci , vol.26 , pp. 4681-4689
    • QUIK, M.1    CHEN, L.2    PARAMESWARAN, N.3    XIE, X.4    LANGSTON, J.W.5    MCCALLUM, S.E.6
  • 145
    • 0029784854 scopus 로고    scopus 로고
    • (S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): A novel and-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors
    • COSFORD ND, BLEICHER L, HERBAUT A et al.: (S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel and-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors. J. Med. Chem. (1996) 39:3235-3237.
    • (1996) J. Med. Chem , vol.39 , pp. 3235-3237
    • COSFORD, N.D.1    BLEICHER, L.2    HERBAUT, A.3
  • 146
    • 33646184356 scopus 로고    scopus 로고
    • Randomized placebo-controlled study of the nicotinic agonist SIB-1508Y in Parkinson disease
    • THE PARKINSON STUDY GROUP
    • THE PARKINSON STUDY GROUP: Randomized placebo-controlled study of the nicotinic agonist SIB-1508Y in Parkinson disease. Neurology (2006) 66:408-410.
    • (2006) Neurology , vol.66 , pp. 408-410
  • 147
    • 33846171220 scopus 로고    scopus 로고
    • Hypothesis about mechanisms through which nicotine might exert its effect on the interdependence of inflammation and gut barrier function in ulcerative colitis
    • MCGILLIGANVE, WALLACE JMW, HEAVEY PM, RIDLEY DL, ROWLAND IR. Hypothesis about mechanisms through which nicotine might exert its effect on the interdependence of inflammation and gut barrier function in ulcerative colitis. Inflamm. Bowel Dis. (2007) 13:108-115.
    • (2007) Inflamm. Bowel Dis , vol.13 , pp. 108-115
    • MCGILLIGAN, V.E.1    WALLACE, J.M.W.2    HEAVEY, P.M.3    RIDLEY, D.L.4    ROWLAND, I.R.5
  • 148
    • 0041570244 scopus 로고    scopus 로고
    • Vagal modulation of spinal nicotine-induced inhibition of the inflammatory response mediated by descending andnociceptive controls
    • MIAO FJP, GREEN P, BENOWITZ N, LEVINE JD: Vagal modulation of spinal nicotine-induced inhibition of the inflammatory response mediated by descending andnociceptive controls. Neuropharmacology (2003) 45:605-611.
    • (2003) Neuropharmacology , vol.45 , pp. 605-611
    • MIAO, F.J.P.1    GREEN, P.2    BENOWITZ, N.3    LEVINE, J.D.4
  • 149
    • 0034695178 scopus 로고    scopus 로고
    • Role of vagus nerve signaling in CNI-1493-mediated suppression of acute inflammation
    • BOROVIKOVA LV, IVANOVA S, NARDI D et al.: Role of vagus nerve signaling in CNI-1493-mediated suppression of acute inflammation. Autonomic Neurosci. Basic Clin. (2000) 85:141-147.
    • (2000) Autonomic Neurosci. Basic Clin , vol.85 , pp. 141-147
    • BOROVIKOVA, L.V.1    IVANOVA, S.2    NARDI, D.3
  • 150
    • 0034713266 scopus 로고    scopus 로고
    • Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
    • BOROVIKOVA EV, IVANOVA S, ZHANG M et al.: Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature (2000) 405:458-462.
    • (2000) Nature , vol.405 , pp. 458-462
    • BOROVIKOVA, E.V.1    IVANOVA, S.2    ZHANG, M.3
  • 151
    • 0037461768 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
    • WANG H, YU M, OCHANI M et al.: Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation. Nature (2003) 421:384-387.
    • (2003) Nature , vol.421 , pp. 384-387
    • WANG, H.1    YU, M.2    OCHANI, M.3
  • 152
    • 33745830175 scopus 로고    scopus 로고
    • Splenectomy inactivates the cholinergic and-inflammatory pathway during lethal endotoxemia and polymicrobial sepsis
    • HUSTON JM, OCHANI M, ROSAS-BALLINA M et al.: Splenectomy inactivates the cholinergic and-inflammatory pathway during lethal endotoxemia and polymicrobial sepsis. J. Exp. Med. (2006) 203:1623-1628.
    • (2006) J. Exp. Med , vol.203 , pp. 1623-1628
    • HUSTON, J.M.1    OCHANI, M.2    ROSAS-BALLINA, M.3
  • 153
    • 9144263639 scopus 로고    scopus 로고
    • Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
    • WANG H, LIAO H, OCHANI M et al.: Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nat. Med. (2004) 10:1216-1221.
    • (2004) Nat. Med , vol.10 , pp. 1216-1221
    • WANG, H.1    LIAO, H.2    OCHANI, M.3
  • 154
    • 20444400552 scopus 로고    scopus 로고
    • The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis
    • VAN WESTERLOO DJ, GIEBELEN IAJ, FLORQUIN S et al.: The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis. J. Infect. Dis. (2005) 191:2138-2148.
    • (2005) J. Infect. Dis , vol.191 , pp. 2138-2148
    • VAN WESTERLOO, D.J.1    GIEBELEN, I.A.J.2    FLORQUIN, S.3
  • 155
    • 0346460961 scopus 로고    scopus 로고
    • Janus kinase 2, an early target of α7 nicotinic acetylcholine recTetor-mediated neuroprotection against Aβ-(1-42) amyloid
    • SHAW S,BENCHERIF M, MARRERO MB: Janus kinase 2, an early target of α7 nicotinic acetylcholine recTetor-mediated neuroprotection against Aβ-(1-42) amyloid. J. Biol. Chem. (2002) 277:44920-44924.
    • (2002) J. Biol. Chem , vol.277 , pp. 44920-44924
    • SHAW, S.1    BENCHERIF, M.2    MARRERO, M.B.3
  • 156
    • 1642343387 scopus 로고    scopus 로고
    • The neuroprotective eflect of 2-(3-pyridyl)-1-azabicyclo[3.2.2]nonane (TC- 1698), a novel α7 ligand, is prevented through angiotensin II activation of a tyrosine phosphatase
    • MARRERO MB, PAPKE RI, BHATTI BS, SHAW S, BENCHERIF M: The neuroprotective eflect of 2-(3-pyridyl)-1-azabicyclo[3.2.2]nonane (TC- 1698), a novel α7 ligand, is prevented through angiotensin II activation of a tyrosine phosphatase. J. Pharmacol. Exp. Ther. (2003) 309:16-27.
    • (2003) J. Pharmacol. Exp. Ther , vol.309 , pp. 16-27
    • MARRERO, M.B.1    PAPKE, R.I.2    BHATTI, B.S.3    SHAW, S.4    BENCHERIF, M.5
  • 157
    • 33748713337 scopus 로고    scopus 로고
    • Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of 1-κB phosphorylation and NF-κB transcriptional activity through nicotinic acetylcholine receptor κ7
    • YOSHIKAWA H, KUROKAWA M, OZAKI N et al.: Nicotine inhibits the production of proinflammatory mediators in human monocytes by suppression of 1-κB phosphorylation and NF-κB transcriptional activity through nicotinic acetylcholine receptor κ7. Clin. Exp. Immunol. (2006) 146:116-123.
    • (2006) Clin. Exp. Immunol , vol.146 , pp. 116-123
    • YOSHIKAWA, H.1    KUROKAWA, M.2    OZAKI, N.3
  • 158
    • 17144370981 scopus 로고    scopus 로고
    • Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation
    • SAEED RW, VARMA S, PENG-NEMEROFF T et al.: Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J. Exp. Med. (2005) 201:1113-1123.
    • (2005) J. Exp. Med , vol.201 , pp. 1113-1123
    • SAEED, R.W.1    VARMA, S.2    PENG-NEMEROFF, T.3
  • 159
    • 34247125289 scopus 로고    scopus 로고
    • Selective ↓-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis
    • PAVLOV VA, OCHANI M, YANG LH et al.: Selective ↓-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis. Crit. Care Med. (2007) 35:1-6.
    • (2007) Crit. Care Med , vol.35 , pp. 1-6
    • PAVLOV, V.A.1    OCHANI, M.2    YANG, L.H.3
  • 160
    • 23644437708 scopus 로고    scopus 로고
    • TNF-α as a promising therapeutic target in chronic asthma: A lesson hom rheumatoid arthritis
    • RUSSO C, POLOSA R: TNF-α as a promising therapeutic target in chronic asthma: a lesson hom rheumatoid arthritis. Clin. Sci. (2005) 109:135-142.
    • (2005) Clin. Sci , vol.109 , pp. 135-142
    • RUSSO, C.1    POLOSA, R.2
  • 161
    • 0033910707 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and imaging
    • GüNDISH D: Nicotinic acetylcholine receptors and imaging. Curr. Pharm. Design. (2000) 6:1143-1157.
    • (2000) Curr. Pharm. Design , vol.6 , pp. 1143-1157
    • GüNDISH, D.1
  • 162
    • 0035251813 scopus 로고    scopus 로고
    • Imaging brain cholinergic activity with positron emission tomography: Its role in the evaluation of cholinergic treatments in Alzheimer's dementia
    • VOLKOW ND, DING Y-S, FOWLER JS et al.: Imaging brain cholinergic activity with positron emission tomography: its role in the evaluation of cholinergic treatments in Alzheimer's dementia. Biol. Psychiatry (2001) 49:211-220.
    • (2001) Biol. Psychiatry , vol.49 , pp. 211-220
    • VOLKOW, N.D.1    DING, Y.-S.2    FOWLER, J.S.3
  • 163
    • 0033837670 scopus 로고    scopus 로고
    • Development of ligands in vivo imaging of cerebral nicotinic receptors
    • SIHVER W, NORDBERG A, LÅNGSTRÖM B et al.: Development of ligands in vivo imaging of cerebral nicotinic receptors. Behav. Brain Res. (2000) 113:143-157.
    • (2000) Behav. Brain Res , vol.113 , pp. 143-157
    • SIHVER, W.1    NORDBERG, A.2    LÅNGSTRÖM, B.3
  • 165
    • 0031595080 scopus 로고    scopus 로고
    • 11C-labeled (S)-aicotine, (S)-3-methyl-5-(1-methyl-2-pyrrohdinyl)isoxazole, and (RS)-1-methyl-2-(3-pyridyl)azeddine as nicotinic receptor ligands for positron emission tomography studies
    • 11C-labeled (S)-aicotine, (S)-3-methyl-5-(1-methyl-2-pyrrohdinyl)isoxazole, and (RS)-1-methyl-2-(3-pyridyl)azeddine as nicotinic receptor ligands for positron emission tomography studies. J. Neurochem. (1998) 71:1750-1760.
    • (1998) J. Neurochem , vol.71 , pp. 1750-1760
    • SHIVER, W.1    FASTH, K.-J.2    ÖGREN, M.3
  • 166
    • 0031002184 scopus 로고    scopus 로고
    • An attempt to visualize baboon brain nicotinic receptors with N-[11C]ABT-418 and N-[11C]methyl-cyrisine
    • VALETTE H, BOTTLAENDER M, DOLLE F, DOLCI L, SYROTA A, CROUZEL C: An attempt to visualize baboon brain nicotinic receptors with N-[11C]ABT-418 and N-[11C]methyl-cyrisine. Nucl. Med. Commun. (1997) 18:164-168.
    • (1997) Nucl. Med. Commun , vol.18 , pp. 164-168
    • VALETTE, H.1    BOTTLAENDER, M.2    DOLLE, F.3    DOLCI, L.4    SYROTA, A.5    CROUZEL, C.6
  • 167
    • 34547560608 scopus 로고    scopus 로고
    • KOZIKOWSKI All CHELLAPPAN SK, HENDERSON D et al.: Acetylenic pyridines for use in PET imaging of nicotinic receptors. ChemMedChem (2007) 2:54-57.
    • KOZIKOWSKI All CHELLAPPAN SK, HENDERSON D et al.: Acetylenic pyridines for use in PET imaging of nicotinic receptors. ChemMedChem (2007) 2:54-57.
  • 168
    • 29944443921 scopus 로고    scopus 로고
    • Widespread decrease of nicotinic acetylcholine receptors in Parkinson's disease
    • FUJITA M, ICHISE M, ZOGHBI S et al. Widespread decrease of nicotinic acetylcholine receptors in Parkinson's disease. Ann. Neurol. (2006) 59:174-177.
    • (2006) Ann. Neurol , vol.59 , pp. 174-177
    • FUJITA, M.1    ICHISE, M.2    ZOGHBI, S.3
  • 169
    • 0025803731 scopus 로고
    • A postmortem study of brain nicotinic receptors in Parkinson's and Alzheimer's disease
    • RJNNE JO, MYLLYKULA T, LONNBERG P et al.: A postmortem study of brain nicotinic receptors in Parkinson's and Alzheimer's disease. Brain Res. (1991) 547:167-170.
    • (1991) Brain Res , vol.547 , pp. 167-170
    • RJNNE, J.O.1    MYLLYKULA, T.2    LONNBERG, P.3
  • 170
    • 0942287662 scopus 로고    scopus 로고
    • Loss of α-conotoxinMII- and A85380-sensitivc nicotinic receptors in Parkinson's disease striatum
    • QUIK M, BORDIA T, FORNO L et al.: Loss of α-conotoxinMII- and A85380-sensitivc nicotinic receptors in Parkinson's disease striatum. J. Neurochem. (2004) 88:668-679.
    • (2004) J. Neurochem , vol.88 , pp. 668-679
    • QUIK, M.1    BORDIA, T.2    FORNO, L.3
  • 171
    • 33748133359 scopus 로고    scopus 로고
    • A-85380: A pharmacological probe for the predinical and clinical investigation of the α4β2 neuronal nicotinic acetylcholine receptor
    • RUETER LE, DONELLY-ROBERTS DL, CURZON P et al.: A-85380: A pharmacological probe for the predinical and clinical investigation of the α4β2 neuronal nicotinic acetylcholine receptor. CNS Drug Rev. (2006) 12:100-112.
    • (2006) CNS Drug Rev , vol.12 , pp. 100-112
    • RUETER, L.E.1    DONELLY-ROBERTS, D.L.2    CURZON, P.3
  • 173
    • 0035057798 scopus 로고    scopus 로고
    • In vivo imaging of nicotinic receptor upregulation following chronic (-)-nicotine treatment in baboon using SPECT
    • KASSIOU M, EBERL S, MEIKLE SR et al.: In vivo imaging of nicotinic receptor upregulation following chronic (-)-nicotine treatment in baboon using SPECT, Nucl. Med. Biol. (2001) 28:165-175.
    • (2001) Nucl. Med. Biol , vol.28 , pp. 165-175
    • KASSIOU, M.1    EBERL, S.2    MEIKLE, S.R.3
  • 174
    • 0037013704 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of [I-125]-iodomethyllycaconitine in the rat
    • NAVARRO HA, XU H, ZHONG D et al.: In vitro and in vivo characterization of [I-125]-iodomethyllycaconitine in the rat. Synapse (2002) 44:117-123.
    • (2002) Synapse , vol.44 , pp. 117-123
    • NAVARRO, H.A.1    XU, H.2    ZHONG, D.3
  • 175
    • 0035888271 scopus 로고    scopus 로고
    • Synthesis and preliminary evaluation of a carbon-11-labelled agonist of the α7 nicotinic acetylcholine receptor
    • DOLLE F, VALETTE H, HINNEN F et al.: Synthesis and preliminary evaluation of a carbon-11-labelled agonist of the α7 nicotinic acetylcholine receptor. J. Label. Compd. Radiopharm. (2001) 44:785-795.
    • (2001) J. Label. Compd. Radiopharm , vol.44 , pp. 785-795
    • DOLLE, F.1    VALETTE, H.2    HINNEN, F.3
  • 176
    • 15844383142 scopus 로고    scopus 로고
    • Synthesis and biodistribution of ractiolabeled α7 nicotinic acetylcholine receptor figands
    • POMPER MG, PHILLIPS E, FAN H et al.: Synthesis and biodistribution of ractiolabeled α7 nicotinic acetylcholine receptor figands. J. Nucl. Med. (2005) 46:326-334.
    • (2005) J. Nucl. Med , vol.46 , pp. 326-334
    • POMPER, M.G.1    PHILLIPS, E.2    FAN, H.3
  • 177
    • 0242300269 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor distribution in relation to spinal neurotransmission pathways
    • KHAN I, OSAKA H, STANISLAUS S et al.: Nicotinic acetylcholine receptor distribution in relation to spinal neurotransmission pathways. J. Comp. Neurol. (2003) 467:44-59.
    • (2003) J. Comp. Neurol , vol.467 , pp. 44-59
    • KHAN, I.1    OSAKA, H.2    STANISLAUS, S.3
  • 178
    • 20044371453 scopus 로고    scopus 로고
    • Ablation of primary afferent terminals reduces nicotinic receptor expression and the nociceptive responses to nicotinic agonists in the spinal cord
    • KHAN I, WENNERHOLM M, SINGLETARY E et al.: Ablation of primary afferent terminals reduces nicotinic receptor expression and the nociceptive responses to nicotinic agonists in the spinal cord. J. Neurol. (2004) 33:543-556.
    • (2004) J. Neurol , vol.33 , pp. 543-556
    • KHAN, I.1    WENNERHOLM, M.2    SINGLETARY, E.3
  • 179
    • 0037145712 scopus 로고    scopus 로고
    • Neuropathy-specific analgesic action of intrathecal nicotinic agonists and its spinal GABA-mediated mechanism
    • RASHID H, UEDA H: Neuropathy-specific analgesic action of intrathecal nicotinic agonists and its spinal GABA-mediated mechanism. Brain Res. (2002) 953:53-62.
    • (2002) Brain Res , vol.953 , pp. 53-62
    • RASHID, H.1    UEDA, H.2
  • 180
    • 33749324999 scopus 로고    scopus 로고
    • Tonic inhibitory role of α4β2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in mice
    • RASHID H, FURUE H, YOSHIMURA M, UEDA H: Tonic inhibitory role of α4β2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in mice. Pain (2006) 125:125-135.
    • (2006) Pain , vol.125 , pp. 125-135
    • RASHID, H.1    FURUE, H.2    YOSHIMURA, M.3    UEDA, H.4
  • 182
    • 2442432828 scopus 로고    scopus 로고
    • Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord
    • CORDERO-ERAUSQUIN M, PONS S, FAURE P, CHANGEUX JP: Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord. Pain (2004) 109:308-318.
    • (2004) Pain , vol.109 , pp. 308-318
    • CORDERO-ERAUSQUIN, M.1    PONS, S.2    FAURE, P.3    CHANGEUX, J.P.4
  • 183
    • 15744403996 scopus 로고    scopus 로고
    • CUCCHIAR0 G, CHAIJALE N, COMMONS KG: The dorsal raphe nucleus as a site of action of the antinociceptive and behavioral effects of the α4 nicotinic receptor agonist epibatidine. J. Pharmacol. Exp. Ther. (2005) 313:389-394.
    • CUCCHIAR0 G, CHAIJALE N, COMMONS KG: The dorsal raphe nucleus as a site of action of the antinociceptive and behavioral effects of the α4 nicotinic receptor agonist epibatidine. J. Pharmacol. Exp. Ther. (2005) 313:389-394.
  • 184
    • 33646686630 scopus 로고    scopus 로고
    • CUCCHIAR0 G, CHAIJALE N, COMMONS KG: The locus coeruleus as a site of action of the antinociceptive and behavioral effects of the nicotinic receptor agonist, epibaridine. Neuropharmacol. (2006) 50:769-776.
    • CUCCHIAR0 G, CHAIJALE N, COMMONS KG: The locus coeruleus as a site of action of the antinociceptive and behavioral effects of the nicotinic receptor agonist, epibaridine. Neuropharmacol. (2006) 50:769-776.
  • 185
    • 0142244688 scopus 로고    scopus 로고
    • Schizophrenia
    • FREEDMAN R. Schizophrenia. N. Eng. J. Med. (2003) 349:1738-1749.
    • (2003) N. Eng. J. Med , vol.349 , pp. 1738-1749
    • FREEDMAN, R.1
  • 186
    • 0036777468 scopus 로고    scopus 로고
    • Nicotine and nicotinic receptors: Relevance to Parkinson's disease
    • QUIK M, KULAK JM. Nicotine and nicotinic receptors: relevance to Parkinson's disease. Neurotoxicology (2002) 23:581-594.
    • (2002) Neurotoxicology , vol.23 , pp. 581-594
    • QUIK, M.1    KULAK, J.M.2
  • 187
    • 0346460961 scopus 로고    scopus 로고
    • Janus Kinase 2, an early target of α7 nicotinic acetylcholine receptor-mediated nearoprotection against Aβ-(1-42) amyloid
    • SHAW S, BENCHERIF M, MARRERO MB: Janus Kinase 2, an early target of α7 nicotinic acetylcholine receptor-mediated nearoprotection against Aβ-(1-42) amyloid. J. Biol. Chem. (2002) 277:44920-44924.
    • (2002) J. Biol. Chem , vol.277 , pp. 44920-44924
    • SHAW, S.1    BENCHERIF, M.2    MARRERO, M.B.3
  • 188
    • 0346749449 scopus 로고    scopus 로고
    • Angiotensin II blocks nicotine-mediated neuroprotection against β-Amyloid (1-42) via activation of the tyrosine phosphatase SHP-1
    • SHAW S, BENCHERIF M, MARRERO MB: Angiotensin II blocks nicotine-mediated neuroprotection against β-Amyloid (1-42) via activation of the tyrosine phosphatase SHP-1. J. Neurosci. (2003) 23:11224-11228.
    • (2003) J. Neurosci , vol.23 , pp. 11224-11228
    • SHAW, S.1    BENCHERIF, M.2    MARRERO, M.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.