Point mutant mice with hypersensitive α4 nicotinic receptors show dopaminergic deficits and increased anxiety

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 5, 2001, Pages 2786-2791

  Labarca, Cesar ^a   Schwarz, Johannes ^a   Deshpande, Purnima ^a   Schwarz, Sigrid ^a   Nowak, Mark W ^a,b   Fonck, Carlos ^a   Nashmi, Raad ^a   Kofuji, Paulo ^c   Dang, Hong ^a   Shi, Wenmei ^a   Fidan, Melihat ^a,b   Khakh, Baljit S ^a   Chen, Zhoufeng ^a   Bowers, Barbara J ^e   Boulter, Jim ^d   Wehner, Jeanne M ^e   Lester, Henry A ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; NICOTINIC RECEPTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; INTRON; LETHALITY; MOUSE; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PATHOPHYSIOLOGY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBSTANTIA NIGRA;

ANIMALS; ANXIETY; DOPAMINE; FEMALE; HETEROZYGOTE; IMMUNOHISTOCHEMISTRY; MICE; MICE, MUTANT STRAINS; POINT MUTATION; PREGNANCY; RATS; RECEPTORS, NICOTINIC;

ANIMALIA;

EID: 0035956994     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.041582598     Document Type: Article

References (36)