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Volumn 6, Issue 5, 2003, Pages 633-639

Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action

Author keywords

Epilepsy; Excitotoxicity; Nicotine addiction; Nicotinic acetylcholine receptors; Smoking cessation

Indexed keywords

NICOTINE; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT;

EID: 0142091438     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (29)

References (43)
  • 1
    • 0024297809 scopus 로고
    • Heterologous expression of excitability proteins: Route to more specific drugs?
    • Lester HA: Heterologous expression of excitability proteins: Route to more specific drugs? Science (1988) 241(4869):1057-1063.
    • (1988) Science , vol.241 , Issue.4869 , pp. 1057-1063
    • Lester, H.A.1
  • 2
    • 0035077202 scopus 로고    scopus 로고
    • Acute effects of nicotine and mecamylamine on tobacco withdrawal symptoms, cigarette reward and ad lib smoking
    • Rose JE, Behm FM, Westman EC: Acute effects of nicotine and mecamylamine on tobacco withdrawal symptoms, cigarette reward and ad lib smoking. Pharmacol Biochem Behav (2001) 68(2):187-197.
    • (2001) Pharmacol Biochem Behav , vol.68 , Issue.2 , pp. 187-197
    • Rose, J.E.1    Behm, F.M.2    Westman, E.C.3
  • 3
    • 0034101820 scopus 로고    scopus 로고
    • 7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth
    • 7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth. J Neurochem (2000) 74(5):2154-2166. The first paper reporting a hypersensitive knockin mouse strain. The allele causes neonatal lethality if not attenuated; the hypersensitivity extends to the level of single-cell electrophysiology, and expression of other nicotinic subunits is unaltered.
    • (2000) J Neurochem , vol.74 , Issue.5 , pp. 2154-2166
    • Orr-Urtreger, A.1    Broide, R.S.2    Kasten, M.R.3    Dang, H.4    Dani, J.A.5    Beaudet, A.L.6    Patrick, J.W.7
  • 9
    • 0037868940 scopus 로고    scopus 로고
    • Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior
    • 2-subunit in specific neuronal populations. High-affinity nAChRs expressed on corticothalamic neurons during development were critical for baseline passive avoidance, and provide a potential substrate for changes induced by prenatal nicotine exposure that cause long-term behavioral and cognitive deficits.
    • (2003) J Neurosci , vol.23 , Issue.9 , pp. 3837-3843
    • King, S.L.1    Marks, M.J.2    Grady, S.R.3    Caldarone, B.J.4    Koren, A.O.5    Mukhin, A.G.6    Collins, A.C.7    Picciotto, M.R.8
  • 10
  • 11
    • 0035899452 scopus 로고    scopus 로고
    • Synaptic plasticity and nicotine addiction
    • Dani JA, Ji D, Zhou FM: Synaptic plasticity and nicotine addiction. Neuron (2001) 31(3):349-352.
    • (2001) Neuron , vol.31 , Issue.3 , pp. 349-352
    • Dani, J.A.1    Ji, D.2    Zhou, F.M.3
  • 12
    • 0036891570 scopus 로고    scopus 로고
    • Cholinergic Interneuron characteristics and nicotinic properties in the striatum
    • Zhou FM, Wilson CJ, Dani JA: Cholinergic Interneuron characteristics and nicotinic properties in the striatum. J Neurobiol (2002) 53(4):590-605.
    • (2002) J Neurobiol , vol.53 , Issue.4 , pp. 590-605
    • Zhou, F.M.1    Wilson, C.J.2    Dani, J.A.3
  • 13
    • 0036582715 scopus 로고    scopus 로고
    • Neuronal systems underlying behaviors related to nicotine addiction: Neural circuits and molecular genetics
    • Picciotto MR, Corrigall WA: Neuronal systems underlying behaviors related to nicotine addiction: Neural circuits and molecular genetics. J Neurosci (2002) 22(9):3338-3341.
    • (2002) J Neurosci , vol.22 , Issue.9 , pp. 3338-3341
    • Picciotto, M.R.1    Corrigall, W.A.2
  • 14
    • 0029953564 scopus 로고    scopus 로고
    • Molecular and cellular aspects of nicotine abuse
    • Dani JA, Heinemann S: Molecular and cellular aspects of nicotine abuse. Neuron (1996) 16(5):905-908.
    • (1996) Neuron , vol.16 , Issue.5 , pp. 905-908
    • Dani, J.A.1    Heinemann, S.2
  • 16
    • 0035180103 scopus 로고    scopus 로고
    • The nicotinic antagonist methyllycaconitine has differential effects on nicotine self-administration and nicotine withdrawal in the rat
    • Markou A, Paterson NE: The nicotinic antagonist methyllycaconitine has differential effects on nicotine self-administration and nicotine withdrawal in the rat. Nicotine Tob Res (2001) 3(4):361-373.
    • (2001) Nicotine Tob Res , vol.3 , Issue.4 , pp. 361-373
    • Markou, A.1    Paterson, N.E.2
  • 17
    • 0029163027 scopus 로고
    • Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors
    • Labarca C, Nowak MW, Zhang H, Tang L, Deshpande P, Lester HA: Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. Nature (1995) 376(6540):514-516.
    • (1995) Nature , vol.376 , Issue.6540 , pp. 514-516
    • Labarca, C.1    Nowak, M.W.2    Zhang, H.3    Tang, L.4    Deshpande, P.5    Lester, H.A.6
  • 19
    • 0029123899 scopus 로고
    • The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating
    • Filatov GN, White MM: The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating. Mol Pharmacol (1995) 48(3):379-384.
    • (1995) Mol Pharmacol , vol.48 , Issue.3 , pp. 379-384
    • Filatov, G.N.1    White, M.M.2
  • 20
    • 0030480913 scopus 로고    scopus 로고
    • Determinants of nicotinic receptor gating in natural and unnatural side chain structures at the M2 9′ position
    • Kearney PC, Zhang H, Zhong W, Dougherty DA, Lester HA: Determinants of nicotinic receptor gating in natural and unnatural side chain structures at the M2 9′ position. Neuron (1996) 17(6):1221-1229.
    • (1996) Neuron , vol.17 , Issue.6 , pp. 1221-1229
    • Kearney, P.C.1    Zhang, H.2    Zhong, W.3    Dougherty, D.A.4    Lester, H.A.5
  • 21
    • 0033621177 scopus 로고    scopus 로고
    • Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes
    • Zhou M, Engel A, Auerbach A: Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes. Proc Natl Acad Sci USA (1999) 96(18):10466-10471. Hypersensitivity to ACh alone does not explain the pathophysiology of the slow-channel syndrome. Instead, some slow-channel alleles are also activated by choline at circulating concentrations. Therefore, the slow-channel syndrome may be an excitotoxic disease due to functional constitutive activation.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.18 , pp. 10466-10471
    • Zhou, M.1    Engel, A.2    Auerbach, A.3
  • 24
    • 0034879826 scopus 로고    scopus 로고
    • Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity
    • Ji D, Lape R, Dani JA: Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron (2001) 31(1):131-141.
    • (2001) Neuron , vol.31 , Issue.1 , pp. 131-141
    • Ji, D.1    Lape, R.2    Dani, J.A.3
  • 29
    • 0033845742 scopus 로고    scopus 로고
    • Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease
    • Maelicke A, Schrattenholz A, Samochocki M, Radina M, Albuquerque EX: Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease. Behav Brain Res (2000) 113(1-2):199-206.
    • (2000) Behav Brain Res , vol.113 , Issue.1-2 , pp. 199-206
    • Maelicke, A.1    Schrattenholz, A.2    Samochocki, M.3    Radina, M.4    Albuquerque, E.X.5
  • 30
    • 0028886560 scopus 로고
    • Different methods of assessing nicotine-induced antinociception may engage different neural mechanisms
    • Caggiula AR, Epstein LH, Perkins KA, Saylor S: Different methods of assessing nicotine-induced antinociception may engage different neural mechanisms. Psychopharmacology (1995) 122(3):301-306.
    • (1995) Psychopharmacology , vol.122 , Issue.3 , pp. 301-306
    • Caggiula, A.R.1    Epstein, L.H.2    Perkins, K.A.3    Saylor, S.4
  • 31
    • 0034037498 scopus 로고    scopus 로고
    • Gain of function mutants: Ion channels and G protein-coupled receptors
    • Lester HA, Karschin A: Gain of function mutants: Ion channels and G protein-coupled receptors. Annu Rev Neurosci (2000) 23:89-125.
    • (2000) Annu Rev Neurosci , vol.23 , pp. 89-125
    • Lester, H.A.1    Karschin, A.2
  • 32
    • 0036703630 scopus 로고    scopus 로고
    • Active calcium accumulation underlies severe weakness in a panel of mice with slow-channel syndrome
    • Gomez CM, Maselli RA, Groshong J, Zayas R, Wollmann RL, Cens T, Charnet P: Active calcium accumulation underlies severe weakness in a panel of mice with slow-channel syndrome. J Neurosci (2002) 22(15):6447-6457. This study models the slow-channel myasthenic syndrome in the muscle nAChRs of transgenic mice.
    • (2002) J Neurosci , vol.22 , Issue.15 , pp. 6447-6457
    • Gomez, C.M.1    Maselli, R.A.2    Groshong, J.3    Zayas, R.4    Wollmann, R.L.5    Cens, T.6    Charnet, P.7
  • 35
    • 0030593642 scopus 로고    scopus 로고
    • Nicotine injections into the ventral tegmental area increase locomotion and Fos-like immunoreactivity in the nucleus accumbens of the rat
    • Panagis G, Nisell M, Nomikos GG, Chergui K, Svensson TH: Nicotine injections into the ventral tegmental area increase locomotion and Fos-like immunoreactivity in the nucleus accumbens of the rat. Brain Res (1996) 730(1-2):133-142.
    • (1996) Brain Res , vol.730 , Issue.1-2 , pp. 133-142
    • Panagis, G.1    Nisell, M.2    Nomikos, G.G.3    Chergui, K.4    Svensson, T.H.5
  • 36
    • 0031870226 scopus 로고    scopus 로고
    • Inducibility of c-Fos protein in visuo-motor system and limbic structures after acute and repeated administration of nicotine in the rat
    • Mathieu-Kia AM, Pages C, Besson MJ: Inducibility of c-Fos protein in visuo-motor system and limbic structures after acute and repeated administration of nicotine in the rat. Synapse (1998) 29(4):343-354.
    • (1998) Synapse , vol.29 , Issue.4 , pp. 343-354
    • Mathieu-Kia, A.M.1    Pages, C.2    Besson, M.J.3
  • 37
    • 0035105903 scopus 로고    scopus 로고
    • Nicotine-induced behavioral sensitization is associated with extracellular dopamine release and expression of c-Fos in the striatum and nucleus accumbens of the rat
    • Shim I, Javaid JI, Wirtshafter D, Jang SY, Shin KH, Lee HJ, Chung YC, Chun BG: Nicotine-induced behavioral sensitization is associated with extracellular dopamine release and expression of c-Fos in the striatum and nucleus accumbens of the rat. Behav Brain Res (2001) 121(1-2):137-147.
    • (2001) Behav Brain Res , vol.121 , Issue.1-2 , pp. 137-147
    • Shim, I.1    Javaid, J.I.2    Wirtshafter, D.3    Jang, S.Y.4    Shin, K.H.5    Lee, H.J.6    Chung, Y.C.7    Chun, B.G.8
  • 38
    • 0020641301 scopus 로고
    • Nicotinic cholinergic receptor binding sites in the brain: Regulation in vivo
    • Schwartz RD, Kellar KJ: Nicotinic cholinergic receptor binding sites in the brain: Regulation in vivo. Science (1983) 220(4593):214-216.
    • (1983) Science , vol.220 , Issue.4593 , pp. 214-216
    • Schwartz, R.D.1    Kellar, K.J.2
  • 39
    • 0020642784 scopus 로고
    • Effects of chronic nicotine infusion on tolerance development and nicotinic receptors
    • Marks MJ, Burch JB, Collins AC: Effects of chronic nicotine infusion on tolerance development and nicotinic receptors. J Pharmacol Exp Ther (1983) 226(3):817-825.
    • (1983) J Pharmacol Exp Ther , vol.226 , Issue.3 , pp. 817-825
    • Marks, M.J.1    Burch, J.B.2    Collins, A.C.3
  • 40
    • 0036499938 scopus 로고    scopus 로고
    • Nicotine addiction: The possible role of functional upregulation
    • Buisson B, Bertrand D: Nicotine addiction: The possible role of functional upregulation. Trends Pharmacol Sci (2002) 23(3):130-136.
    • (2002) Trends Pharmacol Sci , vol.23 , Issue.3 , pp. 130-136
    • Buisson, B.1    Bertrand, D.2
  • 41
    • 1842366036 scopus 로고    scopus 로고
    • Differential regulation of neuronal nicotinic receptor binding sites following chronic nicotine administration
    • Flores CM, Davila-Garcia MI, Ulrich YM, Kellar KJ: Differential regulation of neuronal nicotinic receptor binding sites following chronic nicotine administration. J Neurochem (1997) 69(5):2216-2219.
    • (1997) J Neurochem , vol.69 , Issue.5 , pp. 2216-2219
    • Flores, C.M.1    Davila-Garcia, M.I.2    Ulrich, Y.M.3    Kellar, K.J.4
  • 43
    • 0038112088 scopus 로고    scopus 로고
    • Structure and gating mechanism of the acetylcholine receptor pore
    • Miyazawa A, Fujiyoshi Y, Unwin N: Structure and gating mechanism of the acetylcholine receptor pore. Nature (2003) 424(6943):949-955.
    • (2003) Nature , vol.424 , Issue.6943 , pp. 949-955
    • Miyazawa, A.1    Fujiyoshi, Y.2    Unwin, N.3


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