-
1
-
-
20244364226
-
Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPswe transgenic mice
-
Abbas, N., Bednar, I., Mix, E., Svedberg, M., Paterson, D., Ljungberg, A., Morris, C., Winblad, B., Nordberg, A. & Zhu, J. (2002) Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPswe transgenic mice. J. Neuroimmunol., 126, 50-57.
-
(2002)
J. Neuroimmunol.
, vol.126
, pp. 50-57
-
-
Abbas, N.1
Bednar, I.2
Mix, E.3
Svedberg, M.4
Paterson, D.5
Ljungberg, A.6
Morris, C.7
Winblad, B.8
Nordberg, A.9
Zhu, J.10
-
2
-
-
0035823426
-
Reduction of the cortical amyloid beta levels in guinea pig brain after systemic administration of physostigmine
-
Beach, T.G., Kuo, Y., Schwab, C., Walker, D.G. & Roher, A.E. (2001) Reduction of the cortical amyloid beta levels in guinea pig brain after systemic administration of physostigmine. Neurosci. Lett., 310, 21-24.
-
(2001)
Neurosci. Lett.
, vol.310
, pp. 21-24
-
-
Beach, T.G.1
Kuo, Y.2
Schwab, C.3
Walker, D.G.4
Roher, A.E.5
-
3
-
-
0036318339
-
swe transgenic mice
-
swe transgenic mice. Mol. Cell. Neurosci., 20, 354-365.
-
(2002)
Mol. Cell. Neurosci.
, vol.20
, pp. 354-365
-
-
Bednar, I.1
Paterson, D.2
Marutle, A.3
Pham, T.M.4
Svedberg, M.5
Hellström-Lindahl, E.6
Mousavi, M.7
Court, J.8
Morris, C.9
Perry, E.10
Mohammed, A.11
Zhang, X.12
Nordberg, A.13
-
4
-
-
0037092417
-
Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis
-
Boncristiano, S., Calhoun, M.E., Kelly, PH., Bondolfi, L., Stadler, M., Phinney, A.L., Abramowski, D., Sturchler-Pierrat, C., Enz, A., Sommer, B., Staufenbiel, M. & Jucker, M. (2002) Cholinergic changes in the APP23 transgenic mouse model of cerebral amyloidosis. J. Neurosci., 22, 3234-3243.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3234-3243
-
-
Boncristiano, S.1
Calhoun, M.E.2
Kelly, P.H.3
Bondolfi, L.4
Stadler, M.5
Phinney, A.L.6
Abramowski, D.7
Sturchler-Pierrat, C.8
Enz, A.9
Sommer, B.10
Staufenbiel, M.11
Jucker, M.12
-
5
-
-
0034612256
-
Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice
-
Capsoni, S., Ugolini, G., Comparini, A., Ruberti, F., Berardi, N. & Cattaneo, A. (2000) Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice. Proc. Natl. Acad. Sci. USA, 97, 6826-6831.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6826-6831
-
-
Capsoni, S.1
Ugolini, G.2
Comparini, A.3
Ruberti, F.4
Berardi, N.5
Cattaneo, A.6
-
6
-
-
0037203825
-
Nerve inflammation halts trial for Alzheimer's drug
-
Check, E. (2002) Nerve inflammation halts trial for Alzheimer's drug. Nature, 415, 462.
-
(2002)
Nature
, vol.415
, pp. 462
-
-
Check, E.1
-
7
-
-
0033973980
-
Increased dendritic MAP2 expression in the hippocampus in schizophrenia
-
Cotter, D.S., Wilson, S., Roberts, E., Kerwin, R. & Everall, I.P. (2000) Increased dendritic MAP2 expression in the hippocampus in schizophrenia. Schizophrenia Res., 41, 313-323.
-
(2000)
Schizophrenia Res.
, vol.41
, pp. 313-323
-
-
Cotter, D.S.1
Wilson, S.2
Roberts, E.3
Kerwin, R.4
Everall, I.P.5
-
8
-
-
0037067717
-
β-amyloid peptide activates α7 nicotinic acetylcholine receptors expressed in Xenopus oocytes
-
Dineley, K.T., Bell, K.A., Bui, D. & Sweatt, J.D. (2002) β-amyloid peptide activates α7 nicotinic acetylcholine receptors expressed in Xenopus oocytes. J. Biol. Chem., 277, 25056-25061.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25056-25061
-
-
Dineley, K.T.1
Bell, K.A.2
Bui, D.3
Sweatt, J.D.4
-
9
-
-
0035875962
-
Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease
-
Dineley, K.T., Westerman, M., Bui, D., Bell, K., Ashe, K.H. & Sweatt, J.D. (2001) Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. J. Neurosci., 21, 4125-4133.
-
(2001)
J. Neurosci.
, vol.21
, pp. 4125-4133
-
-
Dineley, K.T.1
Westerman, M.2
Bui, D.3
Bell, K.4
Ashe, K.H.5
Sweatt, J.D.6
-
10
-
-
0036639707
-
Novel therapeutic strategies provide the real test for the amyloid hypothesis of Alzheimer's disease
-
Dominguez, D.I. & De Strooper, B. (2002) Novel therapeutic strategies provide the real test for the amyloid hypothesis of Alzheimer's disease. Trends Pharmacol. Sci., 23, 324-330.
-
(2002)
Trends Pharmacol. Sci.
, vol.23
, pp. 324-330
-
-
Dominguez, D.I.1
De Strooper, B.2
-
11
-
-
0035997231
-
Biogenesis and metabolism of Alzheimer's disease Aβ amyloid peptides
-
Evin, G. & Weidemann, A. (2002) Biogenesis and metabolism of Alzheimer's disease Aβ amyloid peptides. Peptides, 23, 1285-1297.
-
(2002)
Peptides
, vol.23
, pp. 1285-1297
-
-
Evin, G.1
Weidemann, A.2
-
12
-
-
0033528692
-
Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine
-
French, S.J., Humby, T., Horner, C.H., Sofroniew, M.V., Rattray, M., Flores, C.M., Rogers, S.W., Pabreza, L., Wolf, B. & Kellar, K.J. (1999) Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine. Mol. Brain Res., 67, 124-136.
-
(1999)
Mol. Brain Res.
, vol.67
, pp. 124-136
-
-
French, S.J.1
Humby, T.2
Horner, C.H.3
Sofroniew, M.V.4
Rattray, M.5
Flores, C.M.6
Rogers, S.W.7
Pabreza, L.8
Wolf, B.9
Kellar, K.J.10
-
13
-
-
0036718272
-
β-secretase protein and activity are increased in the neocortex in Alzheimer's disease
-
Fukumoto, H., Cheung, B.S., Hyman, B.T. & Irizarry, M.C. (2002) β-secretase protein and activity are increased in the neocortex in Alzheimer's disease. Arch. Neurol., 59, 1381-1389.
-
(2002)
Arch. Neurol.
, vol.59
, pp. 1381-1389
-
-
Fukumoto, H.1
Cheung, B.S.2
Hyman, B.T.3
Irizarry, M.C.4
-
14
-
-
0036959504
-
Regulation of promoter activity of the APP gene by cytokines and growth factors: Implications in Alzheimer's disease
-
Ge, Y.W. & Lahiri, D.K. (2002) Regulation of promoter activity of the APP gene by cytokines and growth factors: implications in Alzheimer's disease. Ann. NY Acad. Sci., 973, 463-467.
-
(2002)
Ann. NY Acad. Sci.
, vol.973
, pp. 463-467
-
-
Ge, Y.W.1
Lahiri, D.K.2
-
15
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road of therapeutics
-
Hardy, J. & Selkoe, D.J. (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road of therapeutics. Science, 297, 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
16
-
-
0036260892
-
Increased expression of amyloid precursor β-secretase in Alzheimer's disease
-
Holsinger, R.M., McLean, C.A., Beyreuther, K., Masters, C.L. & Evin, G. (2002) Increased expression of amyloid precursor β-secretase in Alzheimer's disease. Ann. Neurol., 51, 783-786.
-
(2002)
Ann. Neurol.
, vol.51
, pp. 783-786
-
-
Holsinger, R.M.1
McLean, C.A.2
Beyreuther, K.3
Masters, C.L.4
Evin, G.5
-
17
-
-
0034123538
-
Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model
-
Holtzman, D.M., Pagan, A.M., Mackey, B., Tenkova, T., Sartorius, L., Paul, S.M., Bales, K., Ashe, K.H., Irizarry, M.C. & Hyman, B.T. (2000) Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model. Ann. Neurol., 47, 739-747.
-
(2000)
Ann. Neurol.
, vol.47
, pp. 739-747
-
-
Holtzman, D.M.1
Pagan, A.M.2
Mackey, B.3
Tenkova, T.4
Sartorius, L.5
Paul, S.M.6
Bales, K.7
Ashe, K.H.8
Irizarry, M.C.9
Hyman, B.T.10
-
18
-
-
0029742199
-
Correlative memory deficits, Abeta elevation and amyloid plaques in transgenic mice
-
Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F. & Cole, G. (1996) Correlative memory deficits, Abeta elevation and amyloid plaques in transgenic mice. Science, 274, 99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
19
-
-
0035139547
-
β-site APP cleaving enzyme mRNA expression in APP transgenic mice: Anatomical overlap with transgene expression and static levels with aging
-
Irizarry, M.C., Locascio, J.J. & Hyman, B.T. (2001) β-site APP cleaving enzyme mRNA expression in APP transgenic mice: anatomical overlap with transgene expression and static levels with aging. Am. J. Pathol., 158, 173-177.
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 173-177
-
-
Irizarry, M.C.1
Locascio, J.J.2
Hyman, B.T.3
-
20
-
-
0030612033
-
APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1
-
Irizarry, M.C., McNamara, M., Fedorchak, K., Hsiao, K. & Hyman, B.T. (1997) APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1. J. Neuropathol. Exp. Neurol., 56, 965-973.
-
(1997)
J. Neuropathol. Exp. Neurol.
, vol.56
, pp. 965-973
-
-
Irizarry, M.C.1
McNamara, M.2
Fedorchak, K.3
Hsiao, K.4
Hyman, B.T.5
-
21
-
-
0034700471
-
Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
Janus, C., Pearson, J., McLaurin, J., Mathews, P.M., Jiang, Y., Schmidt, S.D., Christhi, M.A., Horne, P., Heslin, D., French, J., Mount, H.T., Nixon, R.A., Mercken, M., Bergeron, C., Fraser, P.E., St George-Hyslop, P. & Westaway, D. (2000) Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature, 408, 979-982.
-
(2000)
Nature
, vol.408
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Christhi, M.A.7
Horne, P.8
Heslin, D.9
French, J.10
Mount, H.T.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
St George-Hyslop, P.16
Westaway, D.17
-
22
-
-
0037083689
-
Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo
-
Jonnala, R.R., Tery, A.V. & Buccafusco, J.J. (2002) Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo. Life Sci., 70, 1543-1554.
-
(2002)
Life Sci.
, vol.70
, pp. 1543-1554
-
-
Jonnala, R.R.1
Tery, A.V.2
Buccafusco, J.J.3
-
23
-
-
0034727894
-
Acute nicotine decreases, and chronic nicotine increases the expression of brain derived neurotrophic factor mRNA in rat hippocampus
-
Kenny, P.J., File, S.E. & Rattray, M. (2000) Acute nicotine decreases, and chronic nicotine increases the expression of brain derived neurotrophic factor mRNA in rat hippocampus. Mol. Brain Res., 85. 234-238.
-
(2000)
Mol. Brain Res.
, vol.85
, pp. 234-238
-
-
Kenny, P.J.1
File, S.E.2
Rattray, M.3
-
24
-
-
0030880424
-
Enhanced release of secreted form of Alzheimer's amyloid precursor protein from PC12 cells by nicotine
-
Kim, S.H., Kim, Y.K., Jeong, S.J., Haass, C., Kim, Y.H. & Sun, Y.H. (1997) Enhanced release of secreted form of Alzheimer's amyloid precursor protein from PC12 cells by nicotine. Mol. Pharmacol., 52, 430-436.
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 430-436
-
-
Kim, S.H.1
Kim, Y.K.2
Jeong, S.J.3
Haass, C.4
Kim, Y.H.5
Sun, Y.H.6
-
25
-
-
0036310086
-
Nicotinic receptor abnormalities in the cerebellar cortex in autism
-
Lee, M., Martin-Ruiz, C., Graham, A., Court, J., Jaros, E., Perry, R., Iverson, P., Bauman, M. & Perry, E. (2002) Nicotinic receptor abnormalities in the cerebellar cortex in autism. Brain, 125, 1483-1495.
-
(2002)
Brain
, vol.125
, pp. 1483-1495
-
-
Lee, M.1
Martin-Ruiz, C.2
Graham, A.3
Court, J.4
Jaros, E.5
Perry, R.6
Iverson, P.7
Bauman, M.8
Perry, E.9
-
26
-
-
0035836747
-
β-amyloid peptide bocks the response of α7-containing nicotinic receptors on hippocampal neurons
-
Liu, Q.-S., Kawai, H. & Berg, D.K. (2001) β-amyloid peptide bocks the response of α7-containing nicotinic receptors on hippocampal neurons. Proc. Natl. Acad. Sci. USA, 98, 4735-4739.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4735-4739
-
-
Liu, Q.-S.1
Kawai, H.2
Berg, D.K.3
-
27
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O.H., Rosebrough, N.J., Fair, A.L. & Randall, R.J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Fair, A.L.3
Randall, R.J.4
-
28
-
-
0034945151
-
Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia
-
Marutle, A., Zhang, X., Court, J., Piggott, M., Johnson, M., Perry, R., Perry, E. & Nordberg, A. (2001) Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia. J. Chem. Neuroanatomy, 22, 115-126.
-
(2001)
J. Chem. Neuroanatomy
, vol.22
, pp. 115-126
-
-
Marutle, A.1
Zhang, X.2
Court, J.3
Piggott, M.4
Johnson, M.5
Perry, R.6
Perry, E.7
Nordberg, A.8
-
29
-
-
0037223101
-
Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to β-amyloid
-
Matsuoka, Y., Saito, M., LaFrancois, J., Saito, M., Gaynor, K., Olm, V., Wang, L., Casey, E., Lu, Y., Shiratori, C., Lemere, C. & Duff, K. (2003) Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to β-amyloid. J. Neurosci., 23, 29-33.
-
(2003)
J. Neurosci.
, vol.23
, pp. 29-33
-
-
Matsuoka, Y.1
Saito, M.2
LaFrancois, J.3
Saito, M.4
Gaynor, K.5
Olm, V.6
Wang, L.7
Casey, E.8
Lu, Y.9
Shiratori, C.10
Lemere, C.11
Duff, K.12
-
30
-
-
84984755327
-
Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
-
Morgan, D., Diamond, D.M., Gottschall, P.E., Ugen, K.E., Dickey, C., Hardy, J., Duff, K., Jantzen, P., DiCarlo, G., Wilcock, D., Connor, K., Hacher, J., Hope, C., Gordon, M. & Arendash, G.W. (2000) Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature, 408, 982-985.
-
(2000)
Nature
, vol.408
, pp. 982-985
-
-
Morgan, D.1
Diamond, D.M.2
Gottschall, P.E.3
Ugen, K.E.4
Dickey, C.5
Hardy, J.6
Duff, K.7
Jantzen, P.8
DiCarlo, G.9
Wilcock, D.10
Connor, K.11
Hacher, J.12
Hope, C.13
Gordon, M.14
Arendash, G.W.15
-
32
-
-
0037066072
-
Intracellular accumulation of β-amyloid 1-42 in neurons is facilitated by the α7 nicotinic acetylcholine receptor in Alzheimer disease
-
Nagele, R.G., D'Andrea, M.R., Anderson, W.J. & Wang, H.Y. (2002) Intracellular accumulation of β-amyloid 1-42 in neurons is facilitated by the α7 nicotinic acetylcholine receptor in Alzheimer disease. Neuroscience, 110, 199-211.
-
(2002)
Neuroscience
, vol.110
, pp. 199-211
-
-
Nagele, R.G.1
D'Andrea, M.R.2
Anderson, W.J.3
Wang, H.Y.4
-
33
-
-
0037393454
-
Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: A case report
-
Nicoll, J.A.R., Wilkinson, D., Holmes, C., Steart, P., Markham, H. & Weller, R.O. (2003) Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report. Nat. Med., 9, 448-452.
-
(2003)
Nat. Med.
, vol.9
, pp. 448-452
-
-
Nicoll, J.A.R.1
Wilkinson, D.2
Holmes, C.3
Steart, P.4
Markham, H.5
Weller, R.O.6
-
34
-
-
0036316642
-
Chronic nicotine treatment reduces β-amyloidosis in the brain of a mouse model of Alzheimerës disease (APPsw)
-
Nordberg, A., Hellström-Lindahl, E., Lee, M., Johnson, M., Mousavi, M., Hall, R., Perry, E., Bednar, I. & Court, J. (2002) Chronic nicotine treatment reduces β-amyloidosis in the brain of a mouse model of Alzheimerës disease (APPsw). J. Neurochem., 81, 655-658.
-
(2002)
J. Neurochem.
, vol.81
, pp. 655-658
-
-
Nordberg, A.1
Hellström-Lindahl, E.2
Lee, M.3
Johnson, M.4
Mousavi, M.5
Hall, R.6
Perry, E.7
Bednar, I.8
Court, J.9
-
35
-
-
0036838889
-
Nicotine breaks down preformed Alzheimer's beta-amyloid fibrils in vitro
-
Ono, K., Hasegawa, K., Yamada, M. & Naiki, H. (2002) Nicotine breaks down preformed Alzheimer's beta-amyloid fibrils in vitro. Biol. Psychiatry, 52, 880-886.
-
(2002)
Biol. Psychiatry
, vol.52
, pp. 880-886
-
-
Ono, K.1
Hasegawa, K.2
Yamada, M.3
Naiki, H.4
-
37
-
-
0036615884
-
Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a β-sheet breaker peptide
-
Permanne, E., Adessi, C., Saborio, G.P., Fraga, S., Frossard, J., van Dorpe, J., Dewachter, I., Banks, W.A., van Leuven, F. & Soto, C. (2002) Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a β-sheet breaker peptide. FASEB J., 16, 860-862.
-
(2002)
FASEB J.
, vol.16
, pp. 860-862
-
-
Permanne, E.1
Adessi, C.2
Saborio, G.P.3
Fraga, S.4
Frossard, J.5
Van Dorpe, J.6
Dewachter, I.7
Banks, W.A.8
Van Leuven, F.9
Soto, C.10
-
38
-
-
0037112201
-
Cerebral hemorrhage after passive anti-Aβ immunotherapy
-
Pfeifer, M., Boncristiano, S., Bondolfi, L., Stadler, A., Deller, T., Staufenbiel, M., Mathews, P.M. & Jucker, M. (2002) Cerebral hemorrhage after passive anti-Aβ immunotherapy. Science, 298, 139.
-
(2002)
Science
, vol.298
, pp. 139
-
-
Pfeifer, M.1
Boncristiano, S.2
Bondolfi, L.3
Stadler, A.4
Deller, T.5
Staufenbiel, M.6
Mathews, P.M.7
Jucker, M.8
-
39
-
-
0035370860
-
Neuronal and glial β-secretase (BACE) protein expression in transgenic Tg 2576 mice with amyloid plaque pathology
-
Rossner, S., Apelt, J., Schliebs, R., Perez-Polo, J.R. & Bigl, V. (2001) Neuronal and glial β-secretase (BACE) protein expression in transgenic Tg 2576 mice with amyloid plaque pathology. J. Neurosci. Res., 64, 437-446.
-
(2001)
J. Neurosci. Res.
, vol.64
, pp. 437-446
-
-
Rossner, S.1
Apelt, J.2
Schliebs, R.3
Perez-Polo, J.R.4
Bigl, V.5
-
40
-
-
0031836531
-
Long-lasting inactivation of nicotinic receptor function in vitro by treatment with high concentrations of nicotine
-
Rowell, P. & Duggan, D. (1998) Long-lasting inactivation of nicotinic receptor function in vitro by treatment with high concentrations of nicotine. Neuropharmacology, 37, 103-111.
-
(1998)
Neuropharmacology
, vol.37
, pp. 103-111
-
-
Rowell, P.1
Duggan, D.2
-
41
-
-
0034776083
-
Brain-derived neurotrophic factor stimulates beta-amyloid gene promoter activity by a Ras-dependent/AP-1-independent mechanism in SH-SY5Y neuroblastoma cells
-
Ruiz-Leon, Y. & Pascual, A. (2001) Brain-derived neurotrophic factor stimulates beta-amyloid gene promoter activity by a Ras-dependent/AP-1- independent mechanism in SH-SY5Y neuroblastoma cells. J. Neurochem., 79, 278-285.
-
(2001)
J. Neurochem.
, vol.79
, pp. 278-285
-
-
Ruiz-Leon, Y.1
Pascual, A.2
-
42
-
-
0029956783
-
Nicotine inhibits amyloid formation by the β-peptide
-
Salomon, A.R., Marcinowski, K.J., Friedland, R.P. & Zagorski, M.G. (1996) Nicotine inhibits amyloid formation by the β-peptide. Biochemistry, 35, 13568-13578.
-
(1996)
Biochemistry
, vol.35
, pp. 13568-13578
-
-
Salomon, A.R.1
Marcinowski, K.J.2
Friedland, R.P.3
Zagorski, M.G.4
-
43
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., Kholodenko, D., Lee, M., Liao, Z., Lieberburg, I., Motter, R., Mutter, L., Soriano, F., Shopp, G., Vasquez, N., Vandevert, C., Walker, S., Wogulis, M., Yednock, T., Games, D. & Seubert, P. (1999) Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature, 400, 173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
44
-
-
0037454477
-
Early intraneuronal Aβ deposition in the hippocampus of APP transgenic mice
-
Shie, F.-S., LeBoeur, R.C. & Jin, L.-W. (2003) Early intraneuronal Aβ deposition in the hippocampus of APP transgenic mice. Neuroreport, 14, 123-129.
-
(2003)
Neuroreport
, vol.14
, pp. 123-129
-
-
Shie, F.-S.1
LeBoeur, R.C.2
Jin, L.-W.3
-
45
-
-
0000676441
-
Companies halt first Alzheimer vaccine trial
-
Steinberg, D. (2002) Companies halt first Alzheimer vaccine trial. Scientist, 16, 22.
-
(2002)
Scientist
, vol.16
, pp. 22
-
-
Steinberg, D.1
-
46
-
-
0036434569
-
α- and β-secretase: Profound changes in Alzheimer's disease
-
Tyler, SJ., Dawbarn, D., Wilcock, G.K. & Allen, S.J. (2002) α- and β-secretase: profound changes in Alzheimer's disease. Biochem. Biophys. Res. Commun., 299, 373-376.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.299
, pp. 373-376
-
-
Tyler, S.J.1
Dawbarn, D.2
Wilcock, G.K.3
Allen, S.J.4
-
47
-
-
0036813113
-
Nicotine lowers the secretion of the Alzheimer's amyloid beta-protein precursor that contains amyloid beta-peptide in rat
-
Utsuki, T., Shoaib, M., Holloway, H.W., Ingram, D.K., Wallace, W.C., Haroutunian, V., Sambamutti, K., Lahiri, D.K. & Greig, N.H. (2002) Nicotine lowers the secretion of the Alzheimer's amyloid beta-protein precursor that contains amyloid beta-peptide in rat. J. Alzheimers Dis., 4, 405-415.
-
(2002)
J. Alzheimers Dis.
, vol.4
, pp. 405-415
-
-
Utsuki, T.1
Shoaib, M.2
Holloway, H.W.3
Ingram, D.K.4
Wallace, W.C.5
Haroutunian, V.6
Sambamutti, K.7
Lahiri, D.K.8
Greig, N.H.9
-
48
-
-
0037461768
-
Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
-
Wang, H., Yu, M., Ochani, M., Amelia, C.A., Tanovic, M., Susarla, S., Li, J.H., Wang, H., Yang, H., Ulloa, L., Al-Abed, Y., Czura, C.J. & Tracey, K.J. (2003) Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation. Nature, 421, 384-387.
-
(2003)
Nature
, vol.421
, pp. 384-387
-
-
Wang, H.1
Yu, M.2
Ochani, M.3
Amelia, C.A.4
Tanovic, M.5
Susarla, S.6
Li, J.H.7
Wang, H.8
Yang, H.9
Ulloa, L.10
Al-Abed, Y.11
Czura, C.J.12
Tracey, K.J.13
-
49
-
-
0033624509
-
Amyloid peptide Aβ (1-42) binds selectively and with picomolar affinity to α7 nicotine acetylcholine receptors
-
Wang, H.Y., Lee, D.H.S., Davis, C.B. & Shank, R.P. (2000) Amyloid peptide Aβ (1-42) binds selectively and with picomolar affinity to α7 nicotine acetylcholine receptors. J. Neurochem., 75, 1155-1161.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1155-1161
-
-
Wang, H.Y.1
Lee, D.H.S.2
Davis, C.B.3
Shank, R.P.4
-
50
-
-
0035829592
-
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
-
Weggen, S., Eriksen, J., Das, P., Sagi, S.A., Wang, R., Pietrizik, C.U., Findlay, K.A., Smith, T.E., Murphy, M.P., Bulter, T., Kang, D.E., Marquez-Sterling, N., Golde, T.E. & Koo, E.H. (2001) A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity. Nature, 414, 212-216.
-
(2001)
Nature
, vol.414
, pp. 212-216
-
-
Weggen, S.1
Eriksen, J.2
Das, P.3
Sagi, S.A.4
Wang, R.5
Pietrizik, C.U.6
Findlay, K.A.7
Smith, T.E.8
Murphy, M.P.9
Bulter, T.10
Kang, D.E.11
Marquez-Sterling, N.12
Golde, T.E.13
Koo, E.H.14
-
51
-
-
0036833437
-
Therapeutic strategies for Alzheimer's disease
-
Wolfe, M.S. (2002) Therapeutic strategies for Alzheimer's disease. Nature Rev. Drug Discovery, 1, 859-866.
-
(2002)
Nature Rev. Drug Discovery
, vol.1
, pp. 859-866
-
-
Wolfe, M.S.1
-
52
-
-
0037394788
-
Adult mouse astrocytes degrade amyloid β in vitro and in situ
-
Wyss-Coray, T., Loike, J.D., Brionne, T.C., Lu, E., Anankov, R., Yan, F., Silverstein, S.C. & Huseman, J. (2003) Adult mouse astrocytes degrade amyloid β in vitro and in situ. Nat. Med., 9, 453-457.
-
(2003)
Nat. Med.
, vol.9
, pp. 453-457
-
-
Wyss-Coray, T.1
Loike, J.D.2
Brionne, T.C.3
Lu, E.4
Anankov, R.5
Yan, F.6
Silverstein, S.C.7
Huseman, J.8
|