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Volumn 19, Issue 10, 2004, Pages 2703-2710

Nicotine reduces Aβ in the brain and cerebral vessels of APPsw mice

Author keywords

Alzheimer's disease; Neurotrophins; Nicotinic 7 receptors; Sapp; Secretases

Indexed keywords

ALPHA BUNGAROTOXIN; AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; MECAMYLAMINE; NERVE GROWTH FACTOR; NICOTINE; NICOTINIC RECEPTOR;

EID: 2942598335     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0953-816X.2004.03377.x     Document Type: Article
Times cited : (118)

References (52)
  • 1
    • 20244364226 scopus 로고    scopus 로고
    • Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPswe transgenic mice
    • Abbas, N., Bednar, I., Mix, E., Svedberg, M., Paterson, D., Ljungberg, A., Morris, C., Winblad, B., Nordberg, A. & Zhu, J. (2002) Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPswe transgenic mice. J. Neuroimmunol., 126, 50-57.
    • (2002) J. Neuroimmunol. , vol.126 , pp. 50-57
    • Abbas, N.1    Bednar, I.2    Mix, E.3    Svedberg, M.4    Paterson, D.5    Ljungberg, A.6    Morris, C.7    Winblad, B.8    Nordberg, A.9    Zhu, J.10
  • 2
    • 0035823426 scopus 로고    scopus 로고
    • Reduction of the cortical amyloid beta levels in guinea pig brain after systemic administration of physostigmine
    • Beach, T.G., Kuo, Y., Schwab, C., Walker, D.G. & Roher, A.E. (2001) Reduction of the cortical amyloid beta levels in guinea pig brain after systemic administration of physostigmine. Neurosci. Lett., 310, 21-24.
    • (2001) Neurosci. Lett. , vol.310 , pp. 21-24
    • Beach, T.G.1    Kuo, Y.2    Schwab, C.3    Walker, D.G.4    Roher, A.E.5
  • 6
    • 0037203825 scopus 로고    scopus 로고
    • Nerve inflammation halts trial for Alzheimer's drug
    • Check, E. (2002) Nerve inflammation halts trial for Alzheimer's drug. Nature, 415, 462.
    • (2002) Nature , vol.415 , pp. 462
    • Check, E.1
  • 7
  • 8
    • 0037067717 scopus 로고    scopus 로고
    • β-amyloid peptide activates α7 nicotinic acetylcholine receptors expressed in Xenopus oocytes
    • Dineley, K.T., Bell, K.A., Bui, D. & Sweatt, J.D. (2002) β-amyloid peptide activates α7 nicotinic acetylcholine receptors expressed in Xenopus oocytes. J. Biol. Chem., 277, 25056-25061.
    • (2002) J. Biol. Chem. , vol.277 , pp. 25056-25061
    • Dineley, K.T.1    Bell, K.A.2    Bui, D.3    Sweatt, J.D.4
  • 9
    • 0035875962 scopus 로고    scopus 로고
    • Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease
    • Dineley, K.T., Westerman, M., Bui, D., Bell, K., Ashe, K.H. & Sweatt, J.D. (2001) Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. J. Neurosci., 21, 4125-4133.
    • (2001) J. Neurosci. , vol.21 , pp. 4125-4133
    • Dineley, K.T.1    Westerman, M.2    Bui, D.3    Bell, K.4    Ashe, K.H.5    Sweatt, J.D.6
  • 10
    • 0036639707 scopus 로고    scopus 로고
    • Novel therapeutic strategies provide the real test for the amyloid hypothesis of Alzheimer's disease
    • Dominguez, D.I. & De Strooper, B. (2002) Novel therapeutic strategies provide the real test for the amyloid hypothesis of Alzheimer's disease. Trends Pharmacol. Sci., 23, 324-330.
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 324-330
    • Dominguez, D.I.1    De Strooper, B.2
  • 11
    • 0035997231 scopus 로고    scopus 로고
    • Biogenesis and metabolism of Alzheimer's disease Aβ amyloid peptides
    • Evin, G. & Weidemann, A. (2002) Biogenesis and metabolism of Alzheimer's disease Aβ amyloid peptides. Peptides, 23, 1285-1297.
    • (2002) Peptides , vol.23 , pp. 1285-1297
    • Evin, G.1    Weidemann, A.2
  • 13
    • 0036718272 scopus 로고    scopus 로고
    • β-secretase protein and activity are increased in the neocortex in Alzheimer's disease
    • Fukumoto, H., Cheung, B.S., Hyman, B.T. & Irizarry, M.C. (2002) β-secretase protein and activity are increased in the neocortex in Alzheimer's disease. Arch. Neurol., 59, 1381-1389.
    • (2002) Arch. Neurol. , vol.59 , pp. 1381-1389
    • Fukumoto, H.1    Cheung, B.S.2    Hyman, B.T.3    Irizarry, M.C.4
  • 14
    • 0036959504 scopus 로고    scopus 로고
    • Regulation of promoter activity of the APP gene by cytokines and growth factors: Implications in Alzheimer's disease
    • Ge, Y.W. & Lahiri, D.K. (2002) Regulation of promoter activity of the APP gene by cytokines and growth factors: implications in Alzheimer's disease. Ann. NY Acad. Sci., 973, 463-467.
    • (2002) Ann. NY Acad. Sci. , vol.973 , pp. 463-467
    • Ge, Y.W.1    Lahiri, D.K.2
  • 15
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road of therapeutics
    • Hardy, J. & Selkoe, D.J. (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road of therapeutics. Science, 297, 353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 16
    • 0036260892 scopus 로고    scopus 로고
    • Increased expression of amyloid precursor β-secretase in Alzheimer's disease
    • Holsinger, R.M., McLean, C.A., Beyreuther, K., Masters, C.L. & Evin, G. (2002) Increased expression of amyloid precursor β-secretase in Alzheimer's disease. Ann. Neurol., 51, 783-786.
    • (2002) Ann. Neurol. , vol.51 , pp. 783-786
    • Holsinger, R.M.1    McLean, C.A.2    Beyreuther, K.3    Masters, C.L.4    Evin, G.5
  • 18
  • 19
    • 0035139547 scopus 로고    scopus 로고
    • β-site APP cleaving enzyme mRNA expression in APP transgenic mice: Anatomical overlap with transgene expression and static levels with aging
    • Irizarry, M.C., Locascio, J.J. & Hyman, B.T. (2001) β-site APP cleaving enzyme mRNA expression in APP transgenic mice: anatomical overlap with transgene expression and static levels with aging. Am. J. Pathol., 158, 173-177.
    • (2001) Am. J. Pathol. , vol.158 , pp. 173-177
    • Irizarry, M.C.1    Locascio, J.J.2    Hyman, B.T.3
  • 20
    • 0030612033 scopus 로고    scopus 로고
    • APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1
    • Irizarry, M.C., McNamara, M., Fedorchak, K., Hsiao, K. & Hyman, B.T. (1997) APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1. J. Neuropathol. Exp. Neurol., 56, 965-973.
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 965-973
    • Irizarry, M.C.1    McNamara, M.2    Fedorchak, K.3    Hsiao, K.4    Hyman, B.T.5
  • 22
    • 0037083689 scopus 로고    scopus 로고
    • Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo
    • Jonnala, R.R., Tery, A.V. & Buccafusco, J.J. (2002) Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo. Life Sci., 70, 1543-1554.
    • (2002) Life Sci. , vol.70 , pp. 1543-1554
    • Jonnala, R.R.1    Tery, A.V.2    Buccafusco, J.J.3
  • 23
    • 0034727894 scopus 로고    scopus 로고
    • Acute nicotine decreases, and chronic nicotine increases the expression of brain derived neurotrophic factor mRNA in rat hippocampus
    • Kenny, P.J., File, S.E. & Rattray, M. (2000) Acute nicotine decreases, and chronic nicotine increases the expression of brain derived neurotrophic factor mRNA in rat hippocampus. Mol. Brain Res., 85. 234-238.
    • (2000) Mol. Brain Res. , vol.85 , pp. 234-238
    • Kenny, P.J.1    File, S.E.2    Rattray, M.3
  • 24
    • 0030880424 scopus 로고    scopus 로고
    • Enhanced release of secreted form of Alzheimer's amyloid precursor protein from PC12 cells by nicotine
    • Kim, S.H., Kim, Y.K., Jeong, S.J., Haass, C., Kim, Y.H. & Sun, Y.H. (1997) Enhanced release of secreted form of Alzheimer's amyloid precursor protein from PC12 cells by nicotine. Mol. Pharmacol., 52, 430-436.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 430-436
    • Kim, S.H.1    Kim, Y.K.2    Jeong, S.J.3    Haass, C.4    Kim, Y.H.5    Sun, Y.H.6
  • 26
    • 0035836747 scopus 로고    scopus 로고
    • β-amyloid peptide bocks the response of α7-containing nicotinic receptors on hippocampal neurons
    • Liu, Q.-S., Kawai, H. & Berg, D.K. (2001) β-amyloid peptide bocks the response of α7-containing nicotinic receptors on hippocampal neurons. Proc. Natl. Acad. Sci. USA, 98, 4735-4739.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4735-4739
    • Liu, Q.-S.1    Kawai, H.2    Berg, D.K.3
  • 32
    • 0037066072 scopus 로고    scopus 로고
    • Intracellular accumulation of β-amyloid 1-42 in neurons is facilitated by the α7 nicotinic acetylcholine receptor in Alzheimer disease
    • Nagele, R.G., D'Andrea, M.R., Anderson, W.J. & Wang, H.Y. (2002) Intracellular accumulation of β-amyloid 1-42 in neurons is facilitated by the α7 nicotinic acetylcholine receptor in Alzheimer disease. Neuroscience, 110, 199-211.
    • (2002) Neuroscience , vol.110 , pp. 199-211
    • Nagele, R.G.1    D'Andrea, M.R.2    Anderson, W.J.3    Wang, H.Y.4
  • 33
    • 0037393454 scopus 로고    scopus 로고
    • Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: A case report
    • Nicoll, J.A.R., Wilkinson, D., Holmes, C., Steart, P., Markham, H. & Weller, R.O. (2003) Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report. Nat. Med., 9, 448-452.
    • (2003) Nat. Med. , vol.9 , pp. 448-452
    • Nicoll, J.A.R.1    Wilkinson, D.2    Holmes, C.3    Steart, P.4    Markham, H.5    Weller, R.O.6
  • 35
    • 0036838889 scopus 로고    scopus 로고
    • Nicotine breaks down preformed Alzheimer's beta-amyloid fibrils in vitro
    • Ono, K., Hasegawa, K., Yamada, M. & Naiki, H. (2002) Nicotine breaks down preformed Alzheimer's beta-amyloid fibrils in vitro. Biol. Psychiatry, 52, 880-886.
    • (2002) Biol. Psychiatry , vol.52 , pp. 880-886
    • Ono, K.1    Hasegawa, K.2    Yamada, M.3    Naiki, H.4
  • 37
    • 0036615884 scopus 로고    scopus 로고
    • Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a β-sheet breaker peptide
    • Permanne, E., Adessi, C., Saborio, G.P., Fraga, S., Frossard, J., van Dorpe, J., Dewachter, I., Banks, W.A., van Leuven, F. & Soto, C. (2002) Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a β-sheet breaker peptide. FASEB J., 16, 860-862.
    • (2002) FASEB J. , vol.16 , pp. 860-862
    • Permanne, E.1    Adessi, C.2    Saborio, G.P.3    Fraga, S.4    Frossard, J.5    Van Dorpe, J.6    Dewachter, I.7    Banks, W.A.8    Van Leuven, F.9    Soto, C.10
  • 39
    • 0035370860 scopus 로고    scopus 로고
    • Neuronal and glial β-secretase (BACE) protein expression in transgenic Tg 2576 mice with amyloid plaque pathology
    • Rossner, S., Apelt, J., Schliebs, R., Perez-Polo, J.R. & Bigl, V. (2001) Neuronal and glial β-secretase (BACE) protein expression in transgenic Tg 2576 mice with amyloid plaque pathology. J. Neurosci. Res., 64, 437-446.
    • (2001) J. Neurosci. Res. , vol.64 , pp. 437-446
    • Rossner, S.1    Apelt, J.2    Schliebs, R.3    Perez-Polo, J.R.4    Bigl, V.5
  • 40
    • 0031836531 scopus 로고    scopus 로고
    • Long-lasting inactivation of nicotinic receptor function in vitro by treatment with high concentrations of nicotine
    • Rowell, P. & Duggan, D. (1998) Long-lasting inactivation of nicotinic receptor function in vitro by treatment with high concentrations of nicotine. Neuropharmacology, 37, 103-111.
    • (1998) Neuropharmacology , vol.37 , pp. 103-111
    • Rowell, P.1    Duggan, D.2
  • 41
    • 0034776083 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor stimulates beta-amyloid gene promoter activity by a Ras-dependent/AP-1-independent mechanism in SH-SY5Y neuroblastoma cells
    • Ruiz-Leon, Y. & Pascual, A. (2001) Brain-derived neurotrophic factor stimulates beta-amyloid gene promoter activity by a Ras-dependent/AP-1- independent mechanism in SH-SY5Y neuroblastoma cells. J. Neurochem., 79, 278-285.
    • (2001) J. Neurochem. , vol.79 , pp. 278-285
    • Ruiz-Leon, Y.1    Pascual, A.2
  • 44
    • 0037454477 scopus 로고    scopus 로고
    • Early intraneuronal Aβ deposition in the hippocampus of APP transgenic mice
    • Shie, F.-S., LeBoeur, R.C. & Jin, L.-W. (2003) Early intraneuronal Aβ deposition in the hippocampus of APP transgenic mice. Neuroreport, 14, 123-129.
    • (2003) Neuroreport , vol.14 , pp. 123-129
    • Shie, F.-S.1    LeBoeur, R.C.2    Jin, L.-W.3
  • 45
    • 0000676441 scopus 로고    scopus 로고
    • Companies halt first Alzheimer vaccine trial
    • Steinberg, D. (2002) Companies halt first Alzheimer vaccine trial. Scientist, 16, 22.
    • (2002) Scientist , vol.16 , pp. 22
    • Steinberg, D.1
  • 49
    • 0033624509 scopus 로고    scopus 로고
    • Amyloid peptide Aβ (1-42) binds selectively and with picomolar affinity to α7 nicotine acetylcholine receptors
    • Wang, H.Y., Lee, D.H.S., Davis, C.B. & Shank, R.P. (2000) Amyloid peptide Aβ (1-42) binds selectively and with picomolar affinity to α7 nicotine acetylcholine receptors. J. Neurochem., 75, 1155-1161.
    • (2000) J. Neurochem. , vol.75 , pp. 1155-1161
    • Wang, H.Y.1    Lee, D.H.S.2    Davis, C.B.3    Shank, R.P.4
  • 51
    • 0036833437 scopus 로고    scopus 로고
    • Therapeutic strategies for Alzheimer's disease
    • Wolfe, M.S. (2002) Therapeutic strategies for Alzheimer's disease. Nature Rev. Drug Discovery, 1, 859-866.
    • (2002) Nature Rev. Drug Discovery , vol.1 , pp. 859-866
    • Wolfe, M.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.