메뉴 건너뛰기




Volumn 53, Issue 4, 2002, Pages 641-655

Nicotinic receptors in aging and dementia

Author keywords

Acetylcholine; Alzheimer's disease; nAChR; Neuroprotection; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ACETYLCHOLINE; ALCOHOL; AMYLOID BETA PROTEIN; ARACHIDONIC ACID; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CALCIUM BINDING PROTEIN; CASPASE 3; CASPASE 8; CASPASE 9; CHOLINERGIC RECEPTOR; CYTOCHROME C; FIBROBLAST GROWTH FACTOR 2; GLUTAMIC ACID; IBOTENIC ACID; KAINIC ACID; LACTATE DEHYDROGENASE; N METHYL DEXTRO ASPARTIC ACID; NERVE GROWTH FACTOR RECEPTOR; NEUROTOXIN; NEUROTROPHIC FACTOR; NICOTINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNINDEXED DRUG;

EID: 0036890784     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.10102     Document Type: Article
Times cited : (188)

References (144)
  • 2
    • 0028855573 scopus 로고
    • Strain and age differences in acoustic startle responses and effects of nicotine in rats
    • Acri JB, Brown KJ, Saah MI, Grunberg NE. 1995. Strain and age differences in acoustic startle responses and effects of nicotine in rats. Pharmacol Biochem Behav 50:191-198.
    • (1995) Pharmacol Biochem Behav , vol.50 , pp. 191-198
    • Acri, J.B.1    Brown, K.J.2    Saah, M.I.3    Grunberg, N.E.4
  • 3
    • 0028278717 scopus 로고
    • Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity
    • Akaike A, Tamura Y, Yokota T, Shimohama S, Kimura J. 1994. Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity. Brain Res 644:181-187.
    • (1994) Brain Res , vol.644 , pp. 181-187
    • Akaike, A.1    Tamura, Y.2    Yokota, T.3    Shimohama, S.4    Kimura, J.5
  • 4
    • 0036140434 scopus 로고    scopus 로고
    • Smoking as a risk factor for Alzheimer's disease: Contrasting evidence from a systematic review of case-control and cohort studies
    • Review, 49 refs
    • Almeida OP, Hulse GK, Lawrence D, Flicker L. 2002. Smoking as a risk factor for Alzheimer's disease: Contrasting evidence from a systematic review of case-control and cohort studies. [Review] [49 refs]. Addiction 97:15-28.
    • (2002) Addiction , vol.97 , pp. 15-28
    • Almeida, O.P.1    Hulse, G.K.2    Lawrence, D.3    Flicker, L.4
  • 5
    • 0025483929 scopus 로고
    • Effects of aging on nicotinic and muscarinic autoreceptor function in the rat brain: Relationship to presynaptic cholinergic markers and binding sites
    • Araujo DM, Lapchak PA, Meaney MJ, Collier B, Quirion R. 1990. Effects of aging on nicotinic and muscarinic autoreceptor function in the rat brain: Relationship to presynaptic cholinergic markers and binding sites. J Neurosci 10:3069-3078.
    • (1990) J Neurosci , vol.10 , pp. 3069-3078
    • Araujo, D.M.1    Lapchak, P.A.2    Meaney, M.J.3    Collier, B.4    Quirion, R.5
  • 7
    • 0028934741 scopus 로고
    • Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21
    • Arendash GW, Sengstock GJ, Sanberg PR, Kem WR. 1995b. Improved learning and memory in aged rats with chronic administration of the nicotinic receptor agonist GTS-21. Brain Res 674:252-259.
    • (1995) Brain Res , vol.674 , pp. 252-259
    • Arendash, G.W.1    Sengstock, G.J.2    Sanberg, P.R.3    Kem, W.R.4
  • 8
    • 0026501148 scopus 로고
    • Comparative alteration of nicotinic and muscarinic binding sites in Alzheimer's and Parkinson's diseases
    • Aubert I, Araujo DM, Cécyre D, Robitaille Y, Gauthier S, Quirion R. 1992. Comparative alteration of nicotinic and muscarinic binding sites in Alzheimer's and Parkinson's diseases. J Neurochem 58:529-541.
    • (1992) J Neurochem , vol.58 , pp. 529-541
    • Aubert, I.1    Araujo, D.M.2    Cécyre, D.3    Robitaille, Y.4    Gauthier, S.5    Quirion, R.6
  • 9
    • 0002503154 scopus 로고    scopus 로고
    • Beta-amyloid peptides as direct cholinergic neuromodulators: A missing link?
    • Auld DS, Kar S, Quirion R. 1998. Beta-amyloid peptides as direct cholinergic neuromodulators: A missing link? Trends Neurosci 21:43-49.
    • (1998) Trends Neurosci , vol.21 , pp. 43-49
    • Auld, D.S.1    Kar, S.2    Quirion, R.3
  • 10
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • Bartus RT, Dean RLd, Beer B, Lippa AS. 1982. The cholinergic hypothesis of geriatric memory dysfunction. Science 217:408-414.
    • (1982) Science , vol.217 , pp. 408-414
    • Bartus, R.T.1    Dean, R.Ld.2    Beer, B.3    Lippa, A.S.4
  • 11
    • 0026543361 scopus 로고
    • Nicotine enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
    • Behmand RA, Harik SI. 1992. Nicotine enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. J Neurochem 58:776-779.
    • (1992) J Neurochem , vol.58 , pp. 776-779
    • Behmand, R.A.1    Harik, S.I.2
  • 12
    • 0032484494 scopus 로고    scopus 로고
    • Acute intermittent nicotine treatment produces regional increases of basic fibroblast growth factor messenger RNA and protein in the tel- and diencephalon of the rat
    • Belluardo N, Blum M, Mudo G, Andbjer B, Fuxe K. 1998. Acute intermittent nicotine treatment produces regional increases of basic fibroblast growth factor messenger RNA and protein in the tel- and diencephalon of the rat. Neuroscience 83:723-740.
    • (1998) Neuroscience , vol.83 , pp. 723-740
    • Belluardo, N.1    Blum, M.2    Mudo, G.3    Andbjer, B.4    Fuxe, K.5
  • 13
    • 0033402934 scopus 로고    scopus 로고
    • The nicotinic acetylcholine receptor agonist (=)-epibatidine increases FGF-2 mRNA and protein levels in the rat brain
    • Belluardo N, Mudo G, Blum M, Cheng Q, Caniglia G, Dell'Albani P, Fuxe K. 1999a. The nicotinic acetylcholine receptor agonist (=)-epibatidine increases FGF-2 mRNA and protein levels in the rat brain. Mol Brain Res 74:98-110.
    • (1999) Mol Brain Res , vol.74 , pp. 98-110
    • Belluardo, N.1    Mudo, G.2    Blum, M.3    Cheng, Q.4    Caniglia, G.5    Dell'Albani, P.6    Fuxe, K.7
  • 14
    • 0033576771 scopus 로고    scopus 로고
    • The nicotinic acetylcholine receptor agonist ABT-594 increases FGF-2 expression in various rat brain regions
    • Belluardo N, Mudo G, Caniglia G, Cheng Q, Blum M, Fuxe K. 1999b. The nicotinic acetylcholine receptor agonist ABT-594 increases FGF-2 expression in various rat brain regions. NeuroReport 10:3909-3913.
    • (1999) NeuroReport , vol.10 , pp. 3909-3913
    • Belluardo, N.1    Mudo, G.2    Caniglia, G.3    Cheng, Q.4    Blum, M.5    Fuxe, K.6
  • 15
    • 17344368129 scopus 로고    scopus 로고
    • Nicotinic receptor-induced apoptotic cell death of hippocampal progenitor cells
    • Berger F, Gage FH, Vijayaraghavan S. 1998. Nicotinic receptor-induced apoptotic cell death of hippocampal progenitor cells. J Neurosci 18:6871-6881.
    • (1998) J Neurosci , vol.18 , pp. 6871-6881
    • Berger, F.1    Gage, F.H.2    Vijayaraghavan, S.3
  • 16
    • 0030832531 scopus 로고    scopus 로고
    • Expression of alpha 4-1 and alpha 5 nicotinic cholinoceptor mRNA in the aging rat cerebral cortex
    • Birtsch C, Wevers A, Traber J, Maelicke A, Bloch W, Schroder H. 1997. Expression of alpha 4-1 and alpha 5 nicotinic cholinoceptor mRNA in the aging rat cerebral cortex. Neurobiol Aging 18:335-342.
    • (1997) Neurobiol Aging , vol.18 , pp. 335-342
    • Birtsch, C.1    Wevers, A.2    Traber, J.3    Maelicke, A.4    Bloch, W.5    Schroder, H.6
  • 17
    • 0029656194 scopus 로고    scopus 로고
    • Chronic continuous infusion of (-)nicotine reduces basic fibroblast growth factor messenger RNA levels in the ventral midbrain of the intact but not of the 6-hydroxydopamine-lesioned rat
    • Blum M, Wu G, Mudo G, Belluardo N, Andersson K, Agnati LF, Fuxe K. 1996. Chronic continuous infusion of (-)nicotine reduces basic fibroblast growth factor messenger RNA levels in the ventral midbrain of the intact but not of the 6-hydroxydopamine-lesioned rat. Neuroscience 70:169-177.
    • (1996) Neuroscience , vol.70 , pp. 169-177
    • Blum, M.1    Wu, G.2    Mudo, G.3    Belluardo, N.4    Andersson, K.5    Agnati, L.F.6    Fuxe, K.7
  • 19
    • 0030000385 scopus 로고    scopus 로고
    • The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease
    • Breitner JC. 1996. The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease. Annu Rev Med 47:401-411.
    • (1996) Annu Rev Med , vol.47 , pp. 401-411
    • Breitner, J.C.1
  • 20
    • 0025780198 scopus 로고
    • Beneficial effects of nicotine administered prior to a delayed matching-to-sample task in young and aged monkeys
    • Buccafusco JJ, Jackson WJ. 1991. Beneficial effects of nicotine administered prior to a delayed matching-to-sample task in young and aged monkeys. Neurobiol Aging 12:233-238.
    • (1991) Neurobiol Aging , vol.12 , pp. 233-238
    • Buccafusco, J.J.1    Jackson, W.J.2
  • 21
    • 0033372817 scopus 로고    scopus 로고
    • Differential improvement in memory-related task performance with nicotine by aged male and female rhesus monkeys
    • Buccafusco JJ, Jackson WJ, Jonnala RR, Terry Jr AV. 1999. Differential improvement in memory-related task performance with nicotine by aged male and female rhesus monkeys. Behav Pharmacol 10:681-690.
    • (1999) Behav Pharmacol , vol.10 , pp. 681-690
    • Buccafusco, J.J.1    Jackson, W.J.2    Jonnala, R.R.3    Terry A.V., Jr.4
  • 22
    • 0033819553 scopus 로고    scopus 로고
    • Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain
    • Caldarone BJ, Duman CH, Picciotto MR. 2000. Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain. Neuropharmacology 39:2779-2784.
    • (2000) Neuropharmacology , vol.39 , pp. 2779-2784
    • Caldarone, B.J.1    Duman, C.H.2    Picciotto, M.R.3
  • 23
    • 0035816368 scopus 로고    scopus 로고
    • Nicotine produces selective degeneration in the medial habenula and fasciculus retroflexus
    • Carlson J, Noguchi K, Ellison G. 2001. Nicotine produces selective degeneration in the medial habenula and fasciculus retroflexus. Brain Res 906:127-134.
    • (2001) Brain Res , vol.906 , pp. 127-134
    • Carlson, J.1    Noguchi, K.2    Ellison, G.3
  • 24
    • 0031970726 scopus 로고    scopus 로고
    • Nicotine blocks TNF-alpha-mediated neuroprotection to NMDA by an alpha-bungarotoxin-sensitive pathway
    • Carlson NG, Bacchi A, Rogers SW, Gahring LC. 1998. Nicotine blocks TNF-alpha-mediated neuroprotection to NMDA by an alpha-bungarotoxin-sensitive pathway. J Neurobiol 35:29-36.
    • (1998) J Neurobiol , vol.35 , pp. 29-36
    • Carlson, N.G.1    Bacchi, A.2    Rogers, S.W.3    Gahring, L.C.4
  • 25
    • 0026073506 scopus 로고
    • Effects of tobacco smoke constituents on MPTP-induced toxicity and monoamine oxidase activity in the mouse brain
    • Carr LA, Basham JK. 1991. Effects of tobacco smoke constituents on MPTP-induced toxicity and monoamine oxidase activity in the mouse brain. Life Sci 48:1173-1177.
    • (1991) Life Sci , vol.48 , pp. 1173-1177
    • Carr, L.A.1    Basham, J.K.2
  • 26
    • 0035805115 scopus 로고    scopus 로고
    • In vitro effects of nicotine on mitochondrial respiration and superoxide anion generation
    • Cormier A, Morin C, Zini R, Tillement JP, Lagrue G. 2001. In vitro effects of nicotine on mitochondrial respiration and superoxide anion generation. Brain Res 900:72-79.
    • (2001) Brain Res , vol.900 , pp. 72-79
    • Cormier, A.1    Morin, C.2    Zini, R.3    Tillement, J.P.4    Lagrue, G.5
  • 27
    • 0035847204 scopus 로고    scopus 로고
    • Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the substantia nigra
    • Costa G, Abin-Carriquiry JA, Dajas F. 2001. Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the substantia nigra. Brain Res 888:336-342.
    • (2001) Brain Res , vol.888 , pp. 336-342
    • Costa, G.1    Abin-Carriquiry, J.A.2    Dajas, F.3
  • 30
    • 0033626560 scopus 로고    scopus 로고
    • The alpha7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca(2+) dependent mechanism
    • Dajas-Bailador FA, Lima PA, Wonnacott S. 2000. The alpha7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca(2+) dependent mechanism. Neuropharmacology 39:2799-2807.
    • (2000) Neuropharmacology , vol.39 , pp. 2799-2807
    • Dajas-Bailador, F.A.1    Lima, P.A.2    Wonnacott, S.3
  • 31
    • 0023265074 scopus 로고
    • The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system
    • Decker MW. 1987. The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system. Brain Res 434:423-438.
    • (1987) Brain Res , vol.434 , pp. 423-438
    • Decker, M.W.1
  • 32
    • 0035875962 scopus 로고    scopus 로고
    • Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease
    • Dineley KT, Westerman M, Bui D, Bell K, Ashe KH, Sweatt JD. 2001. Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. J Neurosci 21:4125-4133.
    • (2001) J Neurosci , vol.21 , pp. 4125-4133
    • Dineley, K.T.1    Westerman, M.2    Bui, D.3    Bell, K.4    Ashe, K.H.5    Sweatt, J.D.6
  • 33
    • 0029899143 scopus 로고    scopus 로고
    • In vitro neuroprotective properties of the novel cholinergic channel activator (ChCA), ABT-418
    • Donnelly-Roberts DL, Xue IC, Arneric SP, Sullivan JP. 1996. In vitro neuroprotective properties of the novel cholinergic channel activator (ChCA), ABT-418. Brain Res 719:36-44.
    • (1996) Brain Res , vol.719 , pp. 36-44
    • Donnelly-Roberts, D.L.1    Xue, I.C.2    Arneric, S.P.3    Sullivan, J.P.4
  • 36
    • 0027276936 scopus 로고
    • Increased responsiveness of hippocampal pyramidal neurons to nicotine in aged, learning-impaired rats
    • Engstrom DA, Bickford P, De La Garza R, Young D, Rose GM. 1993. Increased responsiveness of hippocampal pyramidal neurons to nicotine in aged, learning-impaired rats. Neurobiol Aging 14:259-266.
    • (1993) Neurobiol Aging , vol.14 , pp. 259-266
    • Engstrom, D.A.1    Bickford, P.2    De La Garza, R.3    Young, D.4    Rose, G.M.5
  • 38
    • 0032742750 scopus 로고    scopus 로고
    • Changes in nicotinic acetylcholine receptor subunit mRNAs and nicotinic binding in spontaneously hypertensive stroke prone rats
    • Ferrari R, Frasoldati A, Leo G, Torri C, Zini I, Agnati LF, Zoli M. 1999. Changes in nicotinic acetylcholine receptor subunit mRNAs and nicotinic binding in spontaneously hypertensive stroke prone rats. Neurosci Lett 277:169-172.
    • (1999) Neurosci Lett , vol.277 , pp. 169-172
    • Ferrari, R.1    Frasoldati, A.2    Leo, G.3    Torri, C.4    Zini, I.5    Agnati, L.F.6    Zoli, M.7
  • 39
    • 0033842094 scopus 로고    scopus 로고
    • Smoking and Parkinson's and Alzheimer's disease: Review of the epidemiological studies
    • Fratiglioni L, Wang HX. 2000. Smoking and Parkinson's and Alzheimer's disease: Review of the epidemiological studies. Beh Brain Res 113:117-120.
    • (2000) Beh Brain Res , vol.113 , pp. 117-120
    • Fratiglioni, L.1    Wang, H.X.2
  • 40
    • 0033528692 scopus 로고    scopus 로고
    • Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine
    • French SJ, Humby T, Horner CH, Sofroniew MV, Rattray M. 1999. Hippocampal neurotrophin and trk receptor mRNA levels are altered by local administration of nicotine, carbachol and pilocarpine. Mol Brain Res 67:124-136.
    • (1999) Mol Brain Res , vol.67 , pp. 124-136
    • French, S.J.1    Humby, T.2    Horner, C.H.3    Sofroniew, M.V.4    Rattray, M.5
  • 41
    • 0035896367 scopus 로고    scopus 로고
    • Acute and chronic nicotine exposure reverse age-related declines in the induction of long-term potentiation in the rat hippocampus
    • Fujii S, Sumikawa K. 2001. Acute and chronic nicotine exposure reverse age-related declines in the induction of long-term potentiation in the rat hippocampus. Brain Res 894:347-353.
    • (2001) Brain Res , vol.894 , pp. 347-353
    • Fujii, S.1    Sumikawa, K.2
  • 42
    • 0025332639 scopus 로고
    • Chronic nicotine treatment increases dopamine levels and reduces dopamine utilization in substantia nigra and in surviving forebrain dopamine nerve terminal systems after a partial di-mesencephalic hemitransection
    • Fuxe K, Janson AM, Jansson A, Andersson K, Eneroth P, Agnati LF. 1990. Chronic nicotine treatment increases dopamine levels and reduces dopamine utilization in substantia nigra and in surviving forebrain dopamine nerve terminal systems after a partial di-mesencephalic hemitransection. Naunyn-Schm Arch Pharmacol 341:171-181.
    • (1990) Naunyn-Schm Arch Pharmacol , vol.341 , pp. 171-181
    • Fuxe, K.1    Janson, A.M.2    Jansson, A.3    Andersson, K.4    Eneroth, P.5    Agnati, L.F.6
  • 43
    • 0028220087 scopus 로고
    • Chronic continuous infusion of nicotine increases the disappearance of choline acetyltransferase immunoreactivity in the cholinergic cell bodies of the medial septal nucleus following a partial unilateral transection of the fimbria fornix
    • Fuxe K, Rosen L, Lippoldt A, Andbjer B, Hasselrot U, Finnman UB, Agnati LF. 1994. Chronic continuous infusion of nicotine increases the disappearance of choline acetyltransferase immunoreactivity in the cholinergic cell bodies of the medial septal nucleus following a partial unilateral transection of the fimbria fornix. Clin Invest 72:262-268.
    • (1994) Clin Invest , vol.72 , pp. 262-268
    • Fuxe, K.1    Rosen, L.2    Lippoldt, A.3    Andbjer, B.4    Hasselrot, U.5    Finnman, U.B.6    Agnati, L.F.7
  • 44
    • 0034616098 scopus 로고    scopus 로고
    • Nicotine attenuates arachidonic acid-induced neurotoxicity in cultured spinal cord neurons
    • Garrido R, Malecki A, Hennig B, Toborek M. 2000. Nicotine attenuates arachidonic acid-induced neurotoxicity in cultured spinal cord neurons. Brain Res 861:59-68.
    • (2000) Brain Res , vol.861 , pp. 59-68
    • Garrido, R.1    Malecki, A.2    Hennig, B.3    Toborek, M.4
  • 45
    • 0035094894 scopus 로고    scopus 로고
    • Nicotine protects against arachidonic-acid-induced caspase activation, cytochrome c release and apoptosis of cultured spinal cord neurons
    • Garrido R, Mattson MP, Hennig B, Toborek M. 2001. Nicotine protects against arachidonic-acid-induced caspase activation, cytochrome c release and apoptosis of cultured spinal cord neurons. J Neurochem 76:1395-1403.
    • (2001) J Neurochem , vol.76 , pp. 1395-1403
    • Garrido, R.1    Mattson, M.P.2    Hennig, B.3    Toborek, M.4
  • 46
    • 0032948548 scopus 로고    scopus 로고
    • Nicotinic receptors in the rat prefrontal cortex: Increase in glutamate release and facilitation of mediodorsal thalamo-cortical transmission
    • Gioanni Y, Rougeot C, Clarke PBS, Lepouse C, Thierry AM, Vidal C. 1999. Nicotinic receptors in the rat prefrontal cortex: Increase in glutamate release and facilitation of mediodorsal thalamo-cortical transmission. Eur J Neurosci 11:18-30.
    • (1999) Eur J Neurosci , vol.11 , pp. 18-30
    • Gioanni, Y.1    Rougeot, C.2    Clarke, P.B.S.3    Lepouse, C.4    Thierry, A.M.5    Vidal, C.6
  • 47
    • 0033846304 scopus 로고    scopus 로고
    • Drugs selective for nicotinic receptor subtypes: A real possibility or a dream?
    • Gotti C, Carbonnelle E, Moretti M, Zwart R, Clementi F. 2000. Drugs selective for nicotinic receptor subtypes: A real possibility or a dream? Beh Brain Res 113:183-192.
    • (2000) Beh Brain Res , vol.113 , pp. 183-192
    • Gotti, C.1    Carbonnelle, E.2    Moretti, M.3    Zwart, R.4    Clementi, F.5
  • 49
    • 0034071673 scopus 로고    scopus 로고
    • Nicotine enhances stimulus detection performance of middle- and old-aged rats: A longitudinal study
    • Grilly DM, Simon BB, Levin ED. 2000. Nicotine enhances stimulus detection performance of middle- and old-aged rats: A longitudinal study. Pharmacol Biochem Behav 65:665-670.
    • (2000) Pharmacol Biochem Behav , vol.65 , pp. 665-670
    • Grilly, D.M.1    Simon, B.B.2    Levin, E.D.3
  • 50
    • 0033983966 scopus 로고    scopus 로고
    • Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease
    • Guan ZZ, Zhang X, Ravid R, Nordberg A. 2000. Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease. J Neurochem 74:237-243.
    • (2000) J Neurochem , vol.74 , pp. 237-243
    • Guan, Z.Z.1    Zhang, X.2    Ravid, R.3    Nordberg, A.4
  • 51
    • 0035666459 scopus 로고    scopus 로고
    • Suppressed expression of nicotinic acetylcholine receptors by nanomolar beta-amyloid peptides in PC12 cells
    • Guan ZZ, Miao H, Tian JY, Unger C, Nordberg A, Zhang X. 2001. Suppressed expression of nicotinic acetylcholine receptors by nanomolar beta-amyloid peptides in PC12 cells. J Neural Trans 108:1417-1433.
    • (2001) J Neural Trans , vol.108 , pp. 1417-1433
    • Guan, Z.Z.1    Miao, H.2    Tian, J.Y.3    Unger, C.4    Nordberg, A.5    Zhang, X.6
  • 53
    • 0343570105 scopus 로고    scopus 로고
    • Modulation of beta-amyloid precursor protein processing and tau phosphorylation by acetylcholine receptors
    • Hellstrom-Lindahl E. 2000. Modulation of beta-amyloid precursor protein processing and tau phosphorylation by acetylcholine receptors. Eur J Pharmacol 393:255-263.
    • (2000) Eur J Pharmacol , vol.393 , pp. 255-263
    • Hellstrom-Lindahl, E.1
  • 54
    • 0028894896 scopus 로고
    • The nicotinic blocking agents d-tubocurare and alpha-bungarotoxin save motoneurons from naturally occurring death in the absence of neuromuscular blockade
    • Hory-Lee F, Frank E. 1995. The nicotinic blocking agents d-tubocurare and alpha-bungarotoxin save motoneurons from naturally occurring death in the absence of neuromuscular blockade. J Neurosci 15:6453-6460.
    • (1995) J Neurosci , vol.15 , pp. 6453-6460
    • Hory-Lee, F.1    Frank, E.2
  • 55
    • 0026528017 scopus 로고
    • Differential effects of acute and chronic nicotine treatment on MPTP-(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced degeneration of nigrostriatal dopamine neurons in the black mouse
    • Janson AM, Fuxe K, Goldstein M. 1992. Differential effects of acute and chronic nicotine treatment on MPTP-(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced degeneration of nigrostriatal dopamine neurons in the black mouse. Clin Invest 70:232-238.
    • (1992) Clin Invest , vol.70 , pp. 232-238
    • Janson, A.M.1    Fuxe, K.2    Goldstein, M.3
  • 56
    • 0023946204 scopus 로고
    • Chronic nicotine treatment partly protects against the 1-methyl-4-phenyl-2,3,6-tetrahydropyridine-induced degeneration of nigrostriatal dopamine neurons in the black mouse
    • Janson AM, Fuxe K, Sundstrom E, Agnati LF, Goldstein M. 1988. Chronic nicotine treatment partly protects against the 1-methyl-4-phenyl-2,3,6-tetrahydropyridine-induced degeneration of nigrostriatal dopamine neurons in the black mouse. Acta Physiol Scand 132:589-591.
    • (1988) Acta Physiol Scand , vol.132 , pp. 589-591
    • Janson, A.M.1    Fuxe, K.2    Sundstrom, E.3    Agnati, L.F.4    Goldstein, M.5
  • 57
    • 0028141854 scopus 로고
    • Chronic nicotine treatment counteracts dopamine D2 receptor upregulation induced by a partial meso-diencephalic hemitransection in the rat
    • Janson AM, Hedlund PB, Fuxe K, von Euler G. 1994. Chronic nicotine treatment counteracts dopamine D2 receptor upregulation induced by a partial meso-diencephalic hemitransection in the rat. Brain Res 655:25-32.
    • (1994) Brain Res , vol.655 , pp. 25-32
    • Janson, A.M.1    Hedlund, P.B.2    Fuxe, K.3    Von Euler, G.4
  • 58
    • 0027489890 scopus 로고
    • Chronic nicotine treatment counteracts nigral cell loss induced by a partial mesodiencephalic hemitransection: An analysis of the total number and mean volume of neurons and glia in substantia nigra of the male rat
    • Janson AM, Moller A. 1993. Chronic nicotine treatment counteracts nigral cell loss induced by a partial mesodiencephalic hemitransection: An analysis of the total number and mean volume of neurons and glia in substantia nigra of the male rat. Neuroscience 57:931-941.
    • (1993) Neuroscience , vol.57 , pp. 931-941
    • Janson, A.M.1    Moller, A.2
  • 59
    • 0037185083 scopus 로고    scopus 로고
    • Stimulation of non-alpha7 nicotinic receptors partially protects dopaminergic neurons from 1-methyl-4-phenylpyridinium-induced toxicity in culture
    • Jeyarasasingam G, Tompkins L, Quik M. 2002. Stimulation of non-alpha7 nicotinic receptors partially protects dopaminergic neurons from 1-methyl-4-phenylpyridinium-induced toxicity in culture. Neuroscience 109:275-285.
    • (2002) Neuroscience , vol.109 , pp. 275-285
    • Jeyarasasingam, G.1    Tompkins, L.2    Quik, M.3
  • 60
    • 0037083689 scopus 로고    scopus 로고
    • Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo
    • Jonnala RR, Terry Jr AV, Buccafusco JJ. 2002. Nicotine increases the expression of high affinity nerve growth factor receptors in both in vitro and in vivo. Life Sci 70:1543-1554.
    • (2002) Life Sci , vol.70 , pp. 1543-1554
    • Jonnala, R.R.1    Terry A.V., Jr.2    Buccafusco, J.J.3
  • 61
    • 0034451731 scopus 로고    scopus 로고
    • Effects of nicotine on blood flow and delayed neuronal death following intermittent transient ischemia in rat hippocampus
    • Kagitani F, Uchida S, Hotta H, Sato A. 2000. Effects of nicotine on blood flow and delayed neuronal death following intermittent transient ischemia in rat hippocampus. Jpn J Physiol 50:585-595.
    • (2000) Jpn J Physiol , vol.50 , pp. 585-595
    • Kagitani, F.1    Uchida, S.2    Hotta, H.3    Sato, A.4
  • 62
    • 0030827671 scopus 로고    scopus 로고
    • Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors
    • Kaneko S, Maeda T, Kume T, Kochiyama H, Akaike A, Shimohama S, Kimura J. 1997. Nicotine protects cultured cortical neurons against glutamate-induced cytotoxicity via alpha7-neuronal receptors and neuronal CNS receptors. Brain Res 765:135-140.
    • (1997) Brain Res , vol.765 , pp. 135-140
    • Kaneko, S.1    Maeda, T.2    Kume, T.3    Kochiyama, H.4    Akaike, A.5    Shimohama, S.6    Kimura, J.7
  • 63
    • 0030767243 scopus 로고    scopus 로고
    • The cholinergic system in Alzheimer's disease
    • Kasa P, Rakonczay Z, Gulya K. 1997. The cholinergic system in Alzheimer's disease. Prog Neurobiol 52:511-535.
    • (1997) Prog Neurobiol , vol.52 , pp. 511-535
    • Kasa, P.1    Rakonczay, Z.2    Gulya, K.3
  • 64
    • 0035957946 scopus 로고    scopus 로고
    • Alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity
    • Kihara T, Shimohama S, Sawada H, Honda K, Nakamizo T, Shibasaki H, Kume T, Akaike A. 2001. Alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity. J Biol Chem 276:13541-13546.
    • (2001) J Biol Chem , vol.276 , pp. 13541-13546
    • Kihara, T.1    Shimohama, S.2    Sawada, H.3    Honda, K.4    Nakamizo, T.5    Shibasaki, H.6    Kume, T.7    Akaike, A.8
  • 68
    • 0030880424 scopus 로고    scopus 로고
    • Enhanced release of secreted form of Alzheimer's amyloid precursor protein from PC12 cells by nicotine
    • Kim SH, Kim YK, Jeong SJ, Haass C, Kim YH, Suh YH. 1997. Enhanced release of secreted form of Alzheimer's amyloid precursor protein from PC12 cells by nicotine. Mol Pharmacol 52:430-436.
    • (1997) Mol Pharmacol , vol.52 , pp. 430-436
    • Kim, S.H.1    Kim, Y.K.2    Jeong, S.J.3    Haass, C.4    Kim, Y.H.5    Suh, Y.H.6
  • 69
    • 0036517068 scopus 로고    scopus 로고
    • Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries
    • to appear
    • Laudenbach V, Medja F, Zoli M, Rossi F, Evrard P, Changeux J, Gressens P. 2002. Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries. FASEB J, to appear.
    • (2002) FASEB J
    • Laudenbach, V.1    Medja, F.2    Zoli, M.3    Rossi, F.4    Evrard, P.5    Changeux, J.6    Gressens, P.7
  • 70
    • 0030051877 scopus 로고    scopus 로고
    • Acute and chronic nicotine effects on working memory in aged rats
    • Levin ED, Torry D. 1996. Acute and chronic nicotine effects on working memory in aged rats. Psychopharmacology 123:88-97.
    • (1996) Psychopharmacology , vol.123 , pp. 88-97
    • Levin, E.D.1    Torry, D.2
  • 71
    • 0034652323 scopus 로고    scopus 로고
    • Nicotine enhances the biosynthesis and secretion of transthyretin from the choroid plexus in rats: Implications for beta-amyloid formation
    • Li MD, Kane JK, Matta SG, Blaner WS, Sharp BM. 2000. Nicotine enhances the biosynthesis and secretion of transthyretin from the choroid plexus in rats: Implications for beta-amyloid formation. J Neurosci 20:1318-1323.
    • (2000) J Neurosci , vol.20 , pp. 1318-1323
    • Li, M.D.1    Kane, J.K.2    Matta, S.G.3    Blaner, W.S.4    Sharp, B.M.5
  • 72
    • 0035836747 scopus 로고    scopus 로고
    • Beta -amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons
    • Liu Q, Kawai H, Berg DK. 2001. Beta -amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons. Proc Natl Acad Sci USA 98:4734-4739.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4734-4739
    • Liu, Q.1    Kawai, H.2    Berg, D.K.3
  • 73
  • 74
    • 0031434470 scopus 로고    scopus 로고
    • Striatal increase of neurotrophic factors as a mechanism of nicotine protection in experimental parkinsonism
    • Maggio R, Riva M, Vaglini F, Fornai F, Racagni G, Corsini GU. 1997. Striatal increase of neurotrophic factors as a mechanism of nicotine protection in experimental parkinsonism. J Neural Transm 104:1113-1123.
    • (1997) J Neural Transm , vol.104 , pp. 1113-1123
    • Maggio, R.1    Riva, M.2    Vaglini, F.3    Fornai, F.4    Racagni, G.5    Corsini, G.U.6
  • 75
    • 0036325889 scopus 로고    scopus 로고
    • Direct evidence that release-stimulating alpha7* nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals
    • Marchi M, Risso F, Viola C, Cavazzani P, Raiteri M. 2002. Direct evidence that release-stimulating alpha7* nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals. J Neurochem 80:1071-1078.
    • (2002) J Neurochem , vol.80 , pp. 1071-1078
    • Marchi, M.1    Risso, F.2    Viola, C.3    Cavazzani, P.4    Raiteri, M.5
  • 76
    • 0028059643 scopus 로고
    • Nicotine protects cultured striatal neurones against N-methyl-D-aspartate receptor-mediated neurotoxicity
    • Marin P, Maus M, Desagher S, Glowinski J, Premont J. 1994. Nicotine protects cultured striatal neurones against N-methyl-D-aspartate receptor-mediated neurotoxicity. NeuroReport 5:1977-1980.
    • (1994) NeuroReport , vol.5 , pp. 1977-1980
    • Marin, P.1    Maus, M.2    Desagher, S.3    Glowinski, J.4    Premont, J.5
  • 77
    • 0032504566 scopus 로고    scopus 로고
    • Regional distribution of subtypes of nicotinic receptors in human brain and effect of aging studied by (±)-[3H]epibatidine
    • Marutle A, Warpman U, Bogdanovic N, Nordberg A. 1998. Regional distribution of subtypes of nicotinic receptors in human brain and effect of aging studied by (±)-[3H]epibatidine. Brain Res 801:143-149.
    • (1998) Brain Res , vol.801 , pp. 143-149
    • Marutle, A.1    Warpman, U.2    Bogdanovic, N.3    Nordberg, A.4
  • 78
    • 0030048606 scopus 로고    scopus 로고
    • Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction
    • Maurice T, Lockhart BP, Privat A. 1996. Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction. Brain Res 706:181-193.
    • (1996) Brain Res , vol.706 , pp. 181-193
    • Maurice, T.1    Lockhart, B.P.2    Privat, A.3
  • 80
    • 0030612747 scopus 로고    scopus 로고
    • Activation of alpha7 nicotinic acetylcholine receptor promotes survival of spinal cord motoneurons
    • Messi ML, Renganathan M, Grigorenko E, Delbono O. 1997. Activation of alpha7 nicotinic acetylcholine receptor promotes survival of spinal cord motoneurons. FEBS Lett 411:32-38.
    • (1997) FEBS Lett , vol.411 , pp. 32-38
    • Messi, M.L.1    Renganathan, M.2    Grigorenko, E.3    Delbono, O.4
  • 81
    • 0037192850 scopus 로고    scopus 로고
    • Nicotine preconditioning antagonizes activity-dependent caspase proteolysis of a glutamate receptor
    • Meyer EL, Gahring LC, Rogers SW. 2002. Nicotine preconditioning antagonizes activity-dependent caspase proteolysis of a glutamate receptor. J Biol Chem 277:10869-10875.
    • (2002) J Biol Chem , vol.277 , pp. 10869-10875
    • Meyer, E.L.1    Gahring, L.C.2    Rogers, S.W.3
  • 82
    • 0032498950 scopus 로고    scopus 로고
    • Neuroprotective effects of 2,4-dimethoxybenzylidene anabaseine (DMXB) and tetrahydroaminoacridine (THA) in neocortices of nucleus basalis lesioned rats
    • Meyer EM, King MA, Meyers C. 1998a. Neuroprotective effects of 2,4-dimethoxybenzylidene anabaseine (DMXB) and tetrahydroaminoacridine (THA) in neocortices of nucleus basalis lesioned rats. Brain Res 786:252-254.
    • (1998) Brain Res , vol.786 , pp. 252-254
    • Meyer, E.M.1    King, M.A.2    Meyers, C.3
  • 83
    • 0031936784 scopus 로고    scopus 로고
    • Neuroprotective and memory-related actions of novel alpha-7 nicotinic agents with different mixed agonist/antagonist properties
    • Meyer EM, Tay ET, Zoltewicz JA, Meyers C, King MA, Papke RL, De Fiebre CM. 1998b. Neuroprotective and memory-related actions of novel alpha-7 nicotinic agents with different mixed agonist/antagonist properties. J Pharmacol Exp Ther 284:1026-1032.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 1026-1032
    • Meyer, E.M.1    Tay, E.T.2    Zoltewicz, J.A.3    Meyers, C.4    King, M.A.5    Papke, R.L.6    De Fiebre, C.M.7
  • 84
    • 0344765458 scopus 로고    scopus 로고
    • Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons
    • Minana MD, Montoliu C, Llansola M, Grisolia S, Felipo V. 1998. Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons. Neuropharmacology 37:847-857.
    • (1998) Neuropharmacology , vol.37 , pp. 847-857
    • Minana, M.D.1    Montoliu, C.2    Llansola, M.3    Grisolia, S.4    Felipo, V.5
  • 85
    • 0028174811 scopus 로고
    • Nicotine effects on the regulation of amyloid precursor protein splicing, neurotrophin and glucose transporter RNA levels in aged rats
    • Monteggia LM, Arneric SP, Giordano T. 1994. Nicotine effects on the regulation of amyloid precursor protein splicing, neurotrophin and glucose transporter RNA levels in aged rats. International J Dev Neurosci 12:133-141.
    • (1994) International J Dev Neurosci , vol.12 , pp. 133-141
    • Monteggia, L.M.1    Arneric, S.P.2    Giordano, T.3
  • 86
    • 0033200231 scopus 로고    scopus 로고
    • Prenatal administration of nicotine results in dopaminergic alterations in the neocortex
    • Muneoka K, Nakatsu T, Fuji J, Ogawa T, Takigawa M. 1999. Prenatal administration of nicotine results in dopaminergic alterations in the neocortex. Neurotoxicol Teratol 21:603-609.
    • (1999) Neurotoxicol Teratol , vol.21 , pp. 603-609
    • Muneoka, K.1    Nakatsu, T.2    Fuji, J.3    Ogawa, T.4    Takigawa, M.5
  • 87
    • 0037066072 scopus 로고    scopus 로고
    • Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha7 nicotinic acetylcholine receptor in Alzheimer's disease
    • Nagele RG, D'Andrea MR, Anderson WJ, Wang HY. 2002. Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha7 nicotinic acetylcholine receptor in Alzheimer's disease. Neuroscience 110:199-211.
    • (2002) Neuroscience , vol.110 , pp. 199-211
    • Nagele, R.G.1    D'Andrea, M.R.2    Anderson, W.J.3    Wang, H.Y.4
  • 88
    • 0034763702 scopus 로고    scopus 로고
    • Nicotine-induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12 cells
    • Nakayama H, Numakawa T, Ikeuchi T, Hatanaka H. 2001. Nicotine-induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12 cells. J Neurochem 79:489-498.
    • (2001) J Neurochem , vol.79 , pp. 489-498
    • Nakayama, H.1    Numakawa, T.2    Ikeuchi, T.3    Hatanaka, H.4
  • 89
    • 0030859444 scopus 로고    scopus 로고
    • GTS-21, a nicotinic agonist, protects against neocortical neuronal cell loss induced by the nucleus basalis magnocellularis lesion in rats
    • Nanri M, Kasahara N, Yamamoto J, Miyake H, Watanabe H. 1997. GTS-21, a nicotinic agonist, protects against neocortical neuronal cell loss induced by the nucleus basalis magnocellularis lesion in rats. Jpn J Pharmacol 74:285-289.
    • (1997) Jpn J Pharmacol , vol.74 , pp. 285-289
    • Nanri, M.1    Kasahara, N.2    Yamamoto, J.3    Miyake, H.4    Watanabe, H.5
  • 90
    • 0032421378 scopus 로고    scopus 로고
    • GTS-21, a nicotinic agonist, attenuates multiple infarctions and cognitive deficit caused by permanent occlusion of bilateral common carotid arteries in rats
    • Nanri M, Miyake H, Murakami Y, Matsumoto K, Watanabe H. 1998. GTS-21, a nicotinic agonist, attenuates multiple infarctions and cognitive deficit caused by permanent occlusion of bilateral common carotid arteries in rats. Jpn J Pharmacol 78:463-469.
    • (1998) Jpn J Pharmacol , vol.78 , pp. 463-469
    • Nanri, M.1    Miyake, H.2    Murakami, Y.3    Matsumoto, K.4    Watanabe, H.5
  • 91
    • 0027031286 scopus 로고
    • Neuroreceptor changes in Alzheimer disease
    • Nordberg A. 1992. Neuroreceptor changes in Alzheimer disease. Cerebrovasc Brain Metab Rev 4:303-328.
    • (1992) Cerebrovasc Brain Metab Rev , vol.4 , pp. 303-328
    • Nordberg, A.1
  • 96
    • 0031926849 scopus 로고    scopus 로고
    • Histological and behavioral protection by (-)-nicotine against quinolinic acid-induced neurodegeneration in the hippocampus
    • O'Neill AB, Morgan SJ, Brioni JD. 1998. Histological and behavioral protection by (-)-nicotine against quinolinic acid-induced neurodegeneration in the hippocampus. Neurobiol Learn Mem 69:46-64.
    • (1998) Neurobiol Learn Mem , vol.69 , pp. 46-64
    • O'Neill, A.B.1    Morgan, S.J.2    Brioni, J.D.3
  • 97
    • 0034821254 scopus 로고    scopus 로고
    • Nicotine affects the signaling of the death pathway, reducing the response of head and neck cancer cell lines to DNA damaging agents
    • Onoda N, Nehmi A, Weiner D, Mujumdar S, Christen R, Los G. 2001. Nicotine affects the signaling of the death pathway, reducing the response of head and neck cancer cell lines to DNA damaging agents. Head Neck 23:860-870.
    • (2001) Head Neck , vol.23 , pp. 860-870
    • Onoda, N.1    Nehmi, A.2    Weiner, D.3    Mujumdar, S.4    Christen, R.5    Los, G.6
  • 98
    • 0024801576 scopus 로고
    • Studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: Comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist
    • Owman C, Fuxe K, Janson AM, Kahrstrom J. 1989. Studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: Comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist. Prog Brain Res 79:267-276.
    • (1989) Prog Brain Res , vol.79 , pp. 267-276
    • Owman, C.1    Fuxe, K.2    Janson, A.M.3    Kahrstrom, J.4
  • 99
    • 0035793423 scopus 로고    scopus 로고
    • Nicotine, but not cotinine, partially protects dopaminergic neurons against MPTP-induced degeneration in mice
    • Parain K, Marchand V, Dumery B, Hirsch E. 2001. Nicotine, but not cotinine, partially protects dopaminergic neurons against MPTP-induced degeneration in mice. Brain Res 890:347-350.
    • (2001) Brain Res , vol.890 , pp. 347-350
    • Parain, K.1    Marchand, V.2    Dumery, B.3    Hirsch, E.4
  • 101
    • 0028890920 scopus 로고
    • Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology
    • Perry EK, Morris CM, Court JA, Cheng A, Fairbairn AF, McKeith IG, Irving D, Brown A, Perry RH. 1995. Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology. Neuroscience 64:385-395.
    • (1995) Neuroscience , vol.64 , pp. 385-395
    • Perry, E.K.1    Morris, C.M.2    Court, J.A.3    Cheng, A.4    Fairbairn, A.F.5    McKeith, I.G.6    Irving, D.7    Brown, A.8    Perry, R.H.9
  • 102
    • 0002006427 scopus 로고    scopus 로고
    • Beta-amyloid 1-42 peptide directly modulates nicotinic receptors in the rat hippocampal slice
    • Pettit DL, Shao Z, Yakel JL. 2001. Beta-amyloid 1-42 peptide directly modulates nicotinic receptors in the rat hippocampal slice. J Neurosci 21:1-5.
    • (2001) J Neurosci , vol.21 , pp. 1-5
    • Pettit, D.L.1    Shao, Z.2    Yakel, J.L.3
  • 104
    • 0035793025 scopus 로고    scopus 로고
    • Chronic nicotine exposure reduces N-methyl-D-aspartate receptor-mediated damage in the hippocampus without altering calcium accumulation or extrusion: Evidence of calbindin-D28K overexpression
    • Prendergast MA, Harris BR, Mayer S, Holley RC, Hauser KF, Littleton JM. 2001a. Chronic nicotine exposure reduces N-methyl-D-aspartate receptor-mediated damage in the hippocampus without altering calcium accumulation or extrusion: Evidence of calbindin-D28K overexpression. Neuroscience 102:75-85.
    • (2001) Neuroscience , vol.102 , pp. 75-85
    • Prendergast, M.A.1    Harris, B.R.2    Mayer, S.3    Holley, R.C.4    Hauser, K.F.5    Littleton, J.M.6
  • 105
    • 0035208026 scopus 로고    scopus 로고
    • Nicotine exposure reduces N-methyl-D-aspartate toxicity in the hippocampus: Relation to distribution of the α7 nicotinic acetylcholine receptor subunit
    • Prendergast MA, Harris BR, Mayer S, Holley RC, Pauly JR, Littleton JM. 2001b. Nicotine exposure reduces N-methyl-D-aspartate toxicity in the hippocampus: Relation to distribution of the α7 nicotinic acetylcholine receptor subunit. Med Sci Monitor 7:1153-1160.
    • (2001) Med Sci Monitor , vol.7 , pp. 1153-1160
    • Prendergast, M.A.1    Harris, B.R.2    Mayer, S.3    Holley, R.C.4    Pauly, J.R.5    Littleton, J.M.6
  • 106
    • 0033773037 scopus 로고    scopus 로고
    • Chronic, but not acute, nicotine exposure attenuates ethanol withdrawal-induced hippocampal damage in vitro
    • Prendergast MA, Harris BR, Mayer S, Littleton JM. 2000. Chronic, but not acute, nicotine exposure attenuates ethanol withdrawal-induced hippocampal damage in vitro. Alcoholism:Clin Exp Res 24:1583-1592.
    • (2000) Alcoholism:Clin Exp Res , vol.24 , pp. 1583-1592
    • Prendergast, M.A.1    Harris, B.R.2    Mayer, S.3    Littleton, J.M.4
  • 107
    • 0034732302 scopus 로고    scopus 로고
    • Nicotinic receptors and Parkinson's disease
    • Quik M, Jeyarasasingam G. 2000. Nicotinic receptors and Parkinson's disease. Eur J Pharmacol 393:223-230.
    • (2000) Eur J Pharmacol , vol.393 , pp. 223-230
    • Quik, M.1    Jeyarasasingam, G.2
  • 108
    • 0035798302 scopus 로고    scopus 로고
    • Nicotine administration reduces striatal MMP+ levels in mice
    • Quik M, Di Monte DA. 2001. Nicotine administration reduces striatal MMP+ levels in mice. Brain Res 917:219-224.
    • (2001) Brain Res , vol.917 , pp. 219-224
    • Quik, M.1    Di Monte, D.A.2
  • 109
    • 0034282064 scopus 로고    scopus 로고
    • Nicotinic receptor losses in dementia with Lewy bodies: Comparisons with Alzheimer's disease
    • Reid RT, Sabbagh MN, Corey-Bloom J, Tiraboschi P, Thal LJ. 2000. Nicotinic receptor losses in dementia with Lewy bodies: Comparisons with Alzheimer's disease. Neurobiol Aging 21:741-746.
    • (2000) Neurobiol Aging , vol.21 , pp. 741-746
    • Reid, R.T.1    Sabbagh, M.N.2    Corey-Bloom, J.3    Tiraboschi, P.4    Thal, L.J.5
  • 110
    • 0028984598 scopus 로고
    • Alpha-BTX lowers neuronal metabolism during the arrest of motoneurone apoptosis
    • Renshaw GM, Dyson SE. 1995. Alpha-BTX lowers neuronal metabolism during the arrest of motoneurone apoptosis. NeuroReport 6:284-288.
    • (1995) NeuroReport , vol.6 , pp. 284-288
    • Renshaw, G.M.1    Dyson, S.E.2
  • 111
    • 0031081092 scopus 로고    scopus 로고
    • Cognitive enhancers in theory and practice: Studies of the cholinergic hypothesis of cognitive deficits in Alzheimer's disease
    • Robbins TW, McAlonan G, Muir JL, Everitt BJ. 1997. Cognitive enhancers in theory and practice: Studies of the cholinergic hypothesis of cognitive deficits in Alzheimer's disease. Behav Brain Res 83:15-23.
    • (1997) Behav Brain Res , vol.83 , pp. 15-23
    • Robbins, T.W.1    McAlonan, G.2    Muir, J.L.3    Everitt, B.J.4
  • 112
    • 0030772890 scopus 로고    scopus 로고
    • Cholinergic activity and amyloid precursor protein metabolism
    • Roberson MR, Harrell LE. 1997. Cholinergic activity and amyloid precursor protein metabolism. Brain Res Rev 25:50-69.
    • (1997) Brain Res Rev , vol.25 , pp. 50-69
    • Roberson, M.R.1    Harrell, L.E.2
  • 113
    • 0032125241 scopus 로고    scopus 로고
    • Age-related changes in neuronal nicotinic acetylcholine receptor subunit alpha4 expression are modified by longterm nicotine administration
    • Rogers SW, Gahring LC, Collins AC, Marks M. 1998. Age-related changes in neuronal nicotinic acetylcholine receptor subunit alpha4 expression are modified by longterm nicotine administration. J Neurosci 18:4825-4832.
    • (1998) J Neurosci , vol.18 , pp. 4825-4832
    • Rogers, S.W.1    Gahring, L.C.2    Collins, A.C.3    Marks, M.4
  • 114
    • 0028003597 scopus 로고
    • Effects of prenatal nicotine exposure on the morphogenesis of somatosensory cortex
    • Roy TS, Sabherwal U. 1994. Effects of prenatal nicotine exposure on the morphogenesis of somatosensory cortex. Neurotoxicol Teratol 16:411-421.
    • (1994) Neurotoxicol Teratol , vol.16 , pp. 411-421
    • Roy, T.S.1    Sabherwal, U.2
  • 115
    • 0033846169 scopus 로고    scopus 로고
    • Nicotinic treatment for degenerative neuropsychiatric disorders such as Alzheimer's disease and Parkinson's disease
    • Rusted JM, Newhouse PA, Levin ED. 2000. Nicotinic treatment for degenerative neuropsychiatric disorders such as Alzheimer's disease and Parkinson's disease. Beh Brain Res 113:121-129.
    • (2000) Beh Brain Res , vol.113 , pp. 121-129
    • Rusted, J.M.1    Newhouse, P.A.2    Levin, E.D.3
  • 116
    • 0035036071 scopus 로고    scopus 로고
    • Dose-related neuroprotective effects of chronic nicotine in 6-hydroxydopamine treated rats, and loss of neuroprotection in alpha4 nicotinic receptor subunit knockout mice
    • Ryan RE, Ross SA, Drago J, Loiacono RE. 2001. Dose-related neuroprotective effects of chronic nicotine in 6-hydroxydopamine treated rats, and loss of neuroprotection in alpha4 nicotinic receptor subunit knockout mice. Br J Pharmacol 132:1650-1656.
    • (2001) Br J Pharmacol , vol.132 , pp. 1650-1656
    • Ryan, R.E.1    Ross, S.A.2    Drago, J.3    Loiacono, R.E.4
  • 118
    • 0025898437 scopus 로고
    • Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease
    • Schroder H, Giacobini E, Struble RG, Zilles K, Maelicke A. 1991. Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease. Neurobiol Aging 12:259-262.
    • (1991) Neurobiol Aging , vol.12 , pp. 259-262
    • Schroder, H.1    Giacobini, E.2    Struble, R.G.3    Zilles, K.4    Maelicke, A.5
  • 119
    • 0027434984 scopus 로고
    • Decline in response to nicotine in aged rat striatum: Correlation with a decrease in a subpopulation of nicotinic receptors
    • Schulz DW, Kuchel GA, Zigmond RE. 1993. Decline in response to nicotine in aged rat striatum: Correlation with a decrease in a subpopulation of nicotinic receptors. J Neurochem 61:2225-2232.
    • (1993) J Neurochem , vol.61 , pp. 2225-2232
    • Schulz, D.W.1    Kuchel, G.A.2    Zigmond, R.E.3
  • 120
    • 0028170818 scopus 로고
    • Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease
    • Selkoe DJ. 1994. Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease. Annu Rev Cell Biol 10:373-403.
    • (1994) Annu Rev Cell Biol , vol.10 , pp. 373-403
    • Selkoe, D.J.1
  • 121
    • 0030574078 scopus 로고    scopus 로고
    • Nicotine protects against the dexamethasone potentiation of kainic acid-induced neurotoxicity in cultured hippocampal neurons
    • Semba J, Miyoshi R, Kito S. 1996. Nicotine protects against the dexamethasone potentiation of kainic acid-induced neurotoxicity in cultured hippocampal neurons. Brain Res 735:335-338.
    • (1996) Brain Res , vol.735 , pp. 335-338
    • Semba, J.1    Miyoshi, R.2    Kito, S.3
  • 122
    • 0022976242 scopus 로고
    • Effect of nicotine and amphetamine on the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice
    • Sershen H, Mason MF, Reith ME, Hashim A, Lajtha A. 1986. Effect of nicotine and amphetamine on the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice. Neuropharmacol 25:1231-1234.
    • (1986) Neuropharmacol , vol.25 , pp. 1231-1234
    • Sershen, H.1    Mason, M.F.2    Reith, M.E.3    Hashim, A.4    Lajtha, A.5
  • 124
    • 0027304745 scopus 로고
    • Effects of chronic nicotine and pilocarpine administration on neocortical neuronal density and [3H]GABA uptake in nucleus basalis lesioned rats
    • Sjak-Shie NN, Meyer EM. 1993. Effects of chronic nicotine and pilocarpine administration on neocortical neuronal density and [3H]GABA uptake in nucleus basalis lesioned rats. Brain Res 624:295-298.
    • (1993) Brain Res , vol.624 , pp. 295-298
    • Sjak-Shie, N.N.1    Meyer, E.M.2
  • 125
    • 0028951951 scopus 로고
    • Cholinergic binding sites in rat brain: Analysis by age and cognitive status
    • Smith TD, Gallagher M, Leslie FM. 1995. Cholinergic binding sites in rat brain: Analysis by age and cognitive status. Neurobiol Aging 16:161-173.
    • (1995) Neurobiol Aging , vol.16 , pp. 161-173
    • Smith, T.D.1    Gallagher, M.2    Leslie, F.M.3
  • 126
    • 0029927802 scopus 로고    scopus 로고
    • Chronic nicotine treatment prevents neuronal loss in neocortex resulting from nucleus basalis lesions in young adult and aged rats
    • Socci DJ, Arendash GW. 1996. Chronic nicotine treatment prevents neuronal loss in neocortex resulting from nucleus basalis lesions in young adult and aged rats. Mol Chem Neuropathol 27:285-305.
    • (1996) Mol Chem Neuropathol , vol.27 , pp. 285-305
    • Socci, D.J.1    Arendash, G.W.2
  • 127
    • 0028801423 scopus 로고
    • Nicotine enhances Morris water maze performance of young and aged rats
    • Socci DJ, Sanberg PR, Arendash GW. 1995. Nicotine enhances Morris water maze performance of young and aged rats. Neurobiol Aging 16:857-860.
    • (1995) Neurobiol Aging , vol.16 , pp. 857-860
    • Socci, D.J.1    Sanberg, P.R.2    Arendash, G.W.3
  • 128
    • 0035906523 scopus 로고    scopus 로고
    • Choline blocks AMPA-induced dark cell degeneration of Purkinje neurons: Potential role of the alpha7 nicotinic receptor
    • Strahlendorf JC, Acosta S, Miles R, Strahlendorf HK. 2001. Choline blocks AMPA-induced dark cell degeneration of Purkinje neurons: Potential role of the alpha7 nicotinic receptor. Brain Res 901:71-78.
    • (2001) Brain Res , vol.901 , pp. 71-78
    • Strahlendorf, J.C.1    Acosta, S.2    Miles, R.3    Strahlendorf, H.K.4
  • 129
    • 0025607117 scopus 로고
    • Nicotinic acetylcholine receptor subtypes in human frontal cortex: Changes in Alzheimer's disease
    • Sugaya K, Giacobini E, Chiappinelli VA. 1990. Nicotinic acetylcholine receptor subtypes in human frontal cortex: Changes in Alzheimer's disease. J Neurosci Res 27:349-359.
    • (1990) J Neurosci Res , vol.27 , pp. 349-359
    • Sugaya, K.1    Giacobini, E.2    Chiappinelli, V.A.3
  • 131
    • 0034090979 scopus 로고    scopus 로고
    • Nicotine attenuates arachidonic acid-induced overexpression of nitric oxide synthase in cultured spinal cord neurons
    • Toborek M, Garrido R, Malecki A, Kaiser S, Mattson MP, Hennig B, Young B. 2000. Nicotine attenuates arachidonic acid-induced overexpression of nitric oxide synthase in cultured spinal cord neurons. Exp Neurol 161:609-620.
    • (2000) Exp Neurol , vol.161 , pp. 609-620
    • Toborek, M.1    Garrido, R.2    Malecki, A.3    Kaiser, S.4    Mattson, M.P.5    Hennig, B.6    Young, B.7
  • 132
    • 0032502612 scopus 로고    scopus 로고
    • Age-related changes in nicotinic acetylcholine receptor subunits alpha4 and beta2 messenger RNA expression in postmortem human frontal cortex and hippocampus
    • Tohgi H, Utsugisawa K, Yoshimura M, Nagane Y, Mihara M. 1998a. Age-related changes in nicotinic acetylcholine receptor subunits alpha4 and beta2 messenger RNA expression in postmortem human frontal cortex and hippocampus. Neurosci Lett 245:139-142.
    • (1998) Neurosci Lett , vol.245 , pp. 139-142
    • Tohgi, H.1    Utsugisawa, K.2    Yoshimura, M.3    Nagane, Y.4    Mihara, M.5
  • 133
    • 0032571764 scopus 로고    scopus 로고
    • Alterations with aging and ischemia in nicotinic acetylcholine receptor subunits alpha4 and beta2 messenger RNA expression in postmortem human putamen. Implications for susceptibility to parkinsonism
    • Tohgi H, Utsugisawa K, Yoshimura M, Nagane Y, Mihara M. 1998b. Alterations with aging and ischemia in nicotinic acetylcholine receptor subunits alpha4 and beta2 messenger RNA expression in postmortem human putamen. Implications for susceptibility to parkinsonism. Brain Res 791:186-190.
    • (1998) Brain Res , vol.791 , pp. 186-190
    • Tohgi, H.1    Utsugisawa, K.2    Yoshimura, M.3    Nagane, Y.4    Mihara, M.5
  • 134
    • 0034625740 scopus 로고    scopus 로고
    • An animal model of adolescent nicotine exposure: Effects on gene expression and macromolecular constituents in rat brain regions
    • Trauth JA, Seidler FJ, Slotkin TA. 2000. An animal model of adolescent nicotine exposure: Effects on gene expression and macromolecular constituents in rat brain regions. Brain Res 867:29-39.
    • (2000) Brain Res , vol.867 , pp. 29-39
    • Trauth, J.A.1    Seidler, F.J.2    Slotkin, T.A.3
  • 135
    • 0030955410 scopus 로고    scopus 로고
    • Effect of stimulation of nicotinic cholinergic receptors on cortical cerebral blood flow and changes in the effect during aging in anesthetized rats
    • Uchida S, Kagitani F, Nakayama H, Sato A. 1997. Effect of stimulation of nicotinic cholinergic receptors on cortical cerebral blood flow and changes in the effect during aging in anesthetized rats. Neurosci Lett 228:203-206.
    • (1997) Neurosci Lett , vol.228 , pp. 203-206
    • Uchida, S.1    Kagitani, F.2    Nakayama, H.3    Sato, A.4
  • 136
    • 0033529754 scopus 로고    scopus 로고
    • Changes with aging and ischemia in nicotinic acetylcholine receptor subunit alpha7 mRNA expression in postmortem human frontal cortex and putamen
    • Utsugisawa K, Nagane Y, Tohgi H, Yoshimura M, Ohba H, Genda Y. 1999. Changes with aging and ischemia in nicotinic acetylcholine receptor subunit alpha7 mRNA expression in postmortem human frontal cortex and putamen. Neurosci Lett 270:145-148.
    • (1999) Neurosci Lett , vol.270 , pp. 145-148
    • Utsugisawa, K.1    Nagane, Y.2    Tohgi, H.3    Yoshimura, M.4    Ohba, H.5    Genda, Y.6
  • 137
    • 0034006944 scopus 로고    scopus 로고
    • Beta-amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology
    • Wang HY, Lee DH, D'Andrea MR, Peterson PA, Shank RP, Reitz AB. 2000. Beta-amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J Biol Chem 275:5626-5632.
    • (2000) J Biol Chem , vol.275 , pp. 5626-5632
    • Wang, H.Y.1    Lee, D.H.2    D'Andrea, M.R.3    Peterson, P.A.4    Shank, R.P.5    Reitz, A.B.6
  • 138
    • 0031045339 scopus 로고    scopus 로고
    • Chronic nicotine treatment enhances focal ischemic brain injury and depletes free pool of brain microvascular tissue plasminogen activator in rats
    • Wang L, Kittaka M, Sun N, Schreiber SS, Zlokovic BV. 1997. Chronic nicotine treatment enhances focal ischemic brain injury and depletes free pool of brain microvascular tissue plasminogen activator in rats. J Cer Blood Flow Metabol 17:136-146.
    • (1997) J Cer Blood Flow Metabol , vol.17 , pp. 136-146
    • Wang, L.1    Kittaka, M.2    Sun, N.3    Schreiber, S.S.4    Zlokovic, B.V.5
  • 139
    • 0029586823 scopus 로고
    • Epibatidine and ABT 418 reveal selective losses of alpha 4 beta 2 nicotinic receptors in Alzheimer brains
    • Warpman U, Nordberg A. 1995. Epibatidine and ABT 418 reveal selective losses of alpha 4 beta 2 nicotinic receptors in Alzheimer brains. NeuroReport 6:2419-2423.
    • (1995) NeuroReport , vol.6 , pp. 2419-2423
    • Warpman, U.1    Nordberg, A.2
  • 140
    • 0030937773 scopus 로고    scopus 로고
    • Nicotine modulates the neurotoxic effect of beta-amyloid protein(25-35) in hippocampal cultures
    • Zamani MR, Allen YS, Owen GP, Gray JA. 1997. Nicotine modulates the neurotoxic effect of beta-amyloid protein(25-35) in hippocampal cultures. NeuroReport 8:513-517.
    • (1997) NeuroReport , vol.8 , pp. 513-517
    • Zamani, M.R.1    Allen, Y.S.2    Owen, G.P.3    Gray, J.A.4
  • 141
    • 0025254609 scopus 로고
    • Influence of development and aging on nicotinic receptor subtypes in rodent brain
    • Zhang X, Wahlstrom G, Nordberg A. 1990. Influence of development and aging on nicotinic receptor subtypes in rodent brain. Int J Dev Neurosci 8:715-721.
    • (1990) Int J Dev Neurosci , vol.8 , pp. 715-721
    • Zhang, X.1    Wahlstrom, G.2    Nordberg, A.3
  • 142
    • 0020083832 scopus 로고
    • Nicotinic ACh receptor blockade and spontaneous nerve cell death in various brain regions
    • Zilles K, Becker CM, Schleicher A. 1982. Nicotinic ACh receptor blockade and spontaneous nerve cell death in various brain regions. Bibliotheca Anatomica 23:40-55.
    • (1982) Bibliotheca Anatomica , vol.23 , pp. 40-55
    • Zilles, K.1    Becker, C.M.2    Schleicher, A.3
  • 143
    • 0345131682 scopus 로고    scopus 로고
    • Identification of four classes of brain nicotinic receptors using β2-mutant mice
    • Zoli M, Léna C, Picciotto MR, Changeux J-P. 1998. Identification of four classes of brain nicotinic receptors using β2-mutant mice. J Neurosci 18:4461-4472.
    • (1998) J Neurosci , vol.18 , pp. 4461-4472
    • Zoli, M.1    Léna, C.2    Picciotto, M.R.3    Changeux, J.-P.4
  • 144
    • 0033104499 scopus 로고    scopus 로고
    • Increased neurodegeneration during aging in mice lacking high-affinity nicotine receptors
    • Zoli M, Picciotto MR, Ferrari R, Cocchi D, Changeux J-P. 1999. Increased neurodegeneration during aging in mice lacking high-affinity nicotine receptors. EMBO J 18:1235-1244.
    • (1999) EMBO J , vol.18 , pp. 1235-1244
    • Zoli, M.1    Picciotto, M.R.2    Ferrari, R.3    Cocchi, D.4    Changeux, J.-P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.