Mast cells and nerves tickle in the tummy. Implications for inflammatory bowel disease and irritable bowel syndrome

Pharmacology and Therapeutics

Volumn 116, Issue 2, 2007, Pages 207-235

  Rijnierse, Anneke ^a   Nijkamp, Frans P ^a   Kraneveld, Aletta D ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Animal models; Enteric nerves; Inflammatory bowel disease; Irritable bowel syndrome; Mast cell nerve interaction; Mast cells

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; 2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; ACETIC ACID; CORTICOSTEROID DERIVATIVE; DEXAMETHASONE; DEXTRAN SULFATE; DOXANTRAZOLE; HISTAMINE; HISTAMINE H2 RECEPTOR ANTAGONIST; IMMUNOGLOBULIN; INFLIXIMAB; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; KETOTIFEN; NATURAL KILLER CELL RECEPTOR; NEUROPEPTIDE; PHOSPHOLIPASE C; PREDNISOLONE; RIFAXIMIN; SEROTONIN; T LYMPHOCYTE RECEPTOR; TRINITROBENZENESULFONIC ACID; TRYPTASE; TUMOR NECROSIS FACTOR ALPHA; TYLOSIN;

ANTIGEN SPECIFICITY; CELL ACTIVATION; CELL INFILTRATION; CELL PROLIFERATION; COLITIS; CYTOKINE PRODUCTION; DRUG INHIBITION; ENTERITIS; GASTROINTESTINAL TRACT; GENETIC MODEL; HUMAN; HUMORAL IMMUNITY; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; INTESTINAL DYSMOTILITY; INTESTINE INNERVATION; IRRITABLE COLON; MAST CELL; MOUSE STRAIN; NERVE CELL; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; SKIN SENSITIZATION; TH2 CELL; TRICHINELLA SPIRALIS;

ANIMALS; DISEASE MODELS, ANIMAL; ENTERIC NERVOUS SYSTEM; HUMANS; INFLAMMATION MEDIATORS; INFLAMMATORY BOWEL DISEASES; IRRITABLE BOWEL SYNDROME; MAST CELLS; NEURONS;

EID: 34548853957     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2007.06.008     Document Type: Review

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