Mast cell stabilizer ketotifen [4-(1-methyl-4-piperidylidene)-4H-benzo[4,5] cyclohepta[1,2-b]thiophen-10(9H)-one fumarate] prevents mucosal mast cell hyperplasia and intestinal dysmotility in experimental Trichinella spiralis inflammation in the rat

Journal of Pharmacology and Experimental Therapeutics

Volumn 319, Issue 3, 2006, Pages 1104-1111

  Serna, H ^a   Porras, M ^a   Vergara, Patri ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMASE; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; KETOTIFEN; MAST CELL PROTEASE II; MYELOPEROXIDASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CELL HYPERPLASIA; CONTROLLED STUDY; DRUG EFFECT; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTESTINAL DYSMOTILITY; MALE; MAST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRICHINELLA SPIRALIS; TRICHINOSIS;

ANIMALS; CELL COUNT; CELL SIZE; CHOLECYSTOKININ; CHYMASES; CYCLOOXYGENASE 2; GASTROINTESTINAL MOTILITY; HISTAMINE H1 ANTAGONISTS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTESTINAL MUCOSA; KETOTIFEN; MALE; MAST CELLS; NITRIC OXIDE SYNTHASE TYPE II; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY; TRICHINELLA SPIRALIS; TRICHINOSIS;

EID: 33751175222     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.104620     Document Type: Article

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