Activation of human mast cells by aggregated IgG through FcγRI: Additive effects of C3a

Clinical Immunology

Volumn 110, Issue 2, 2004, Pages 172-180

  Woolhiser, Michael R ^a,b   Brockow, Knut ^a   Metcalfe, Dean D ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b DOW CHEMICAL COMPANY   (United States)

Author keywords

hexosaminidase; C3a; Cytokine; Degranulation; Fc receptor; IgG; Mast cell; Taqman

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; CD64 ANTIGEN; COMPLEMENT COMPONENT C3A; CYTOKINE; FC RECEPTOR; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; ICOSANOID; IMMUNOGLOBULIN F(AB')2 FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; INTERLEUKIN 13; INTERLEUKIN 3; LEUKOTRIENE C4; PROSTAGLANDIN D2; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME RELEASE; HEATING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOGLOBULIN AGGREGATE; IMMUNOPATHOLOGY; INFLAMMATION; MAST CELL; MAST CELL DEGRANULATION; MEDIATOR; PRIORITY JOURNAL; PROTEIN DETERMINATION;

BETA-N-ACETYLHEXOSAMINIDASE; CELL DEGRANULATION; COMPLEMENT C3A; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULIN G; INTERFERON TYPE II; LEUKOTRIENE C4; MAST CELLS; PROSTAGLANDIN D2; RECEPTORS, IGG; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 1542300936     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clim.2003.11.007     Document Type: Article

References (42)

1. Malone D.G., Metcalfe D.D. Mast cells and arthritis. Ann. Allergy. 61:1988;27-30.
2. Malone D.G., Wilder R.L., Saavedra-Delgado A.M., Metcalfe D.D. Mast cell numbers in rheumatoid synovial tissues. Arthritis Rheum. 30:1987;130-137.
3. Mican J.M., Metcalfe D.D. Arthritis and mast cell activation. J. Allergy Clin. Immunol. 86:1990;677-683.
4. Chanez P., Lacoste J., Guillot B., Giron J., Barneon G., Enander I.et al. Mast cells' contribution to the fibrosing alveolitis of the scleroderma lung. Am. Rev. Respir. Dis. 147:1993;1497-1502.
5. Akimoto S., Ishikawa O., Igarashi Y., Kurosawa M., Miyachi Y. Dermal mast cells in scleroderma: their skin density, tryptase/chymase phenotypes and degranulation. Br. J. Dermatol. 138:1998;399-406.
6. Mehregan D.R., Gibson L.E. Pathophysiology of urticarial vasculitis. Arch. Dermatol. 134:1998;88-89.
7. Okayama Y., Kirshenbaum A.S., Metcalfe D.D. Expression of a functional high affinity IgG receptor, FcγRI, on human mast cells: up-regulation by IFN-γ J. Immunol. 164:2000;4332-4339.
8. Rottem M., Okada T., Goff J.P., Metcalfe D.D. Mast cells cultured from the peripheral blood of normal donors and patients with mastocytosis originate from a CD34+/Fc epsilon RI-cell population. Blood. 84:1994;2489-2496.
9. Kimura I., Moritani Y., Tanizaki Y. Basophils in bronchial asthma with reference to reagin-type allergy. Clin. Allergy. 3:1973;195-202.
10. Kawata N., Takata M., Suwaki T., Tanimoto Y., Soda R., Takahashi K.et al. Signal transduction by IgG receptors induces calcium mobilization, but not histamine release, in the human basophilic cell line KU812F. Int. Arch. Allergy Immunol. 109:1996;27-34.
11. Okayama Y., Hagaman D.D., Metcalfe D.D. A comparison of mediators released or generated by IFN-γ treated human mast cells following aggregation of FcγRI or FceRI. J. Immunol. 166:2001;4705-4712.
12. Heid C.A., Stevens J., Livak K.J., Williams P.M. Real time quantitative PCR. Genome Res. 6:1996;986-994.
13. Woolhiser M.R., Okayama Y., Gilfillan A.M., Metcalfe D.D. IgG-dependent activation of human mast cells following up-regulation of FcgammaRI by IFN-gamma. Eur. J. Immunol. 31:2001;3298-3307.
14. Dougherty G., Selvendran Y., Murdoch S., Palmer D., Hogg N. The human mononuclear phagocyte high-affinity Fc receptor, FcRI, defined by a monoclonal antibody, 10.1. Eur. J. Immunol. 17:1987;1453-1459.
15. Moodley I., Mongar J.L. IgG receptors on the mast cell. Agents Actions. 11:1981;77-83.
16. Benhamou M., Berenstein E., Jouvin M., Siraganian R. The receptor with high affinity for IgE on rat mast cells is a functional receptor for rat IgG2a. Mol. Immunol. 31:1994;1089-1097.
17. Phillips J., Brouwer W., Edwards M., Mahler S., Ruhno J., Collins A. The effectiveness of different rat IgG subclasses as IgE-blocking antibodies in the rat basophilic leukaemia cell model. Immunol. Cell Biol. 77:1999;121-126.
18. Okayama Y., Hagaman D.D., Woolhiser M., Metcalfe D.D. Further characterization of FcγRII and FcγRIII expression by cultured human mast cells. Int. Arch. Allergy Immunol. 124:2001;155-157.
19. Mousli M., Hugli T., Landry Y., Bronner C. A mechanism of action for anaphylatoxin C3a stimulation of mast cells. J. Immunol. 148:1992;2456-2461.
20. Johnson A., Hugli T., Muller-Eberhard H. Release of histamine from rat mast cells by the complement peptides C3a and C5a. Immunology. 28:1975;1067.
21. Zwirner J., Gotze O., Sieber A., Kapp A., Begemann G., Zuberbier T.et al. The human mast cell line HMC-1 binds and responds to C3a but not C3a(desArg). Scand. J. Immunol. 47:1998;19-24.
22. Ali H., Ahamed J., Hernandez-Munain C., Baron J., Krangel M., Patel D. Chemokine production by G protein-coupled receptor activation in a human mast cell line: roles of extracellular signal-regulated kinase and NFAT. J. Immunol. 165:2000;7215-7223.
23. Nilsson G., Johnell M., Hammer C.H., Tiffany H.L., Nilsson K., Metcalfe D.D.et al. C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway. J. Immunol. 157:1996;1693-1698.
24. Hulett M.D., Hogarth P.M. Molecular basis of Fc receptor function. Adv. Immunol. 57:1994;1-127.
25. Kubota Y. The effect of human anaphylatoxins and neutrophils on histamine release from isolated human skin mast cells. J. Dermatol. 19:1992;19-26.
26. Anderson C., Abraham G. Characterization of the Fc receptor for IgG on a human macrophage cell line, U937. J. Immunol. 125:1980;2735-2741.
27. Okayama Y., Tkaczyk C., Metcalfe D.D., Gilfillan A.M. Comparison of Fc epsilon RI- and Fc gamma RI-mediated degranulation and TNF-alpha synthesis in human mast cells: selective utilization of phosphatidylinositol-3-kinase for Fc gamma RI-induced degranulation. Eur. J. Immunol. 33:2003;1450-1459.
28. Lilja I., Gustafson-Svard C., Franzen L., Sjodahl R. Tumor necrosis factor-alpha in ileal mast cells in patients with Crohn's disease. Digestion. 61:2000;68-76.
29. Bischoff S.C., Lorentz A., Schwengberg S., Weier G., Raab R., Manns M.P. Mast cells are an important cellular source of tumour necrosis factor alpha in human intestinal tissue. Gut. 44:1999;643-652.
30. Raza A. Anti-TNF therapies in rheumatoid arthritis, Crohn's disease, sepsis, and myelodysplastic syndromes. Microsc. Res. Tech. 50:2000;229-235.
31. Mekori Y.A., Metcalfe D.D. Mast cells in innate immunity. Immunol. Rev. 173:2000;131-140.
32. Tkaczyk C., Gilfillan A.M. FcεRI-dependent signaling pathways in human mast cells. Clin. Immunol. 99:2001;198-210.
33. Daëron M. Fc receptor biology. Annu. Rev. Immunol. 15:1997;203-234.
34. Edberg J.C., Qin H., Gibson A.W., Yee A.M.F., Redecha P.B., Indik Z.K.et al. The CY domain of the FcgammaRIa alpha-chain (CD64) alter gamma-chain tyrosine-based signaling and phagocytosis. J. Biol. Chem. 277:2002;41287-41293.
35. Ames R.S., Li Y., Sarau H.M., Nuthulaganti P., Foley J.J., Ellis C.et al. Molecular cloning and characterization of the human anaphylatoxin C3a receptor. J. Biol. Chem. 271:1996;20231-20234.
36. Crass T., Raffetseder U., Martin U., Grove M., Klos A., Kohl J.et al. Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cells. Eur. J. Immunol. 26:1996;1944-1950.
37. Tkaczyk C., Okayama Y., Woolhiser M.R., Hagaman D.D., Gilfillan A.M., Metcalfe D.D. Activation of human mast cells through the high affinity IgG receptor. Mol. Immunol. 38:2002;1289-1293.
38. Gotis-Graham I., Smith M.D., Parker A., McNeil H.P. Synovial mast cell responses during clinical improvement in early rheumatoid arthritis. Ann. Rheum. Dis. 57:1998;664-671.
39. Tetlow L.C., Woolley D.E. Distribution, activation and tryptase/chymase phenotype of mast cells in the rheumatoid lesion. Ann. Rheum. Dis. 54:1995;549-555.
40. Eneström S., Bengtsson A., Frödin T. Dermal IgG deposits and increase of mast cells in patients with fibromyalgia - relevant findings or epiphenomena? Scand. J. Rheumatol. 26:1997;308-313.
41. Tetlow L.C., Woolley D.E. Histamine stimulates matrix metalloproteinase-3 and -13 production by human articular chondrocytes in vitro. Ann. Rheum. Dis. 61:2002;737-740.
42. Tetlow L.C., Woolley D.E. Mast cells, cytokines, and metalloproteinases at the rheumatoid lesion: dual immunolocalisation studies. Ann. Rheum. Dis. 54:1995;896-903.