Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons

Journal of Physiology

Volumn 547, Issue 2, 2003, Pages 531-542

  Reed, David E ^a   Barajas Lopez, Carlos ^a   Cottrell, Graeme ^b   Velazquez Rocha, Sara ^b   Dery, Olivier ^b   Grady, Eileen F ^b   Bunnett, Nigel W ^b   Vanner, Stephen J ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; HISTAMINE; PROSTAGLANDIN; PROTEINASE ACTIVATED RECEPTOR 2; SEROTONIN; SOYBEAN TRYPSIN INHIBITOR; TRYPSIN; TRYPTASE; VASOACTIVE INTESTINAL POLYPEPTIDE; MESSENGER RNA;

ACTION POTENTIAL; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; AUTONOMIC NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; DESENSITIZATION; ENZYME RELEASE; EXCITATORY POSTSYNAPTIC POTENTIAL; GUINEA PIG; ILEUM MUCOSA; IMMUNOCOMPETENT CELL; IMMUNOREACTIVITY; INTRACELLULAR RECORDING; MAST CELL DEGRANULATION; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE CONDUCTANCE; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SIGNAL TRANSDUCTION; ADULT; ANIMAL CELL; ARTICLE; AUTONOMIC NERVOUS SYSTEM; HARTLEY GUINEA PIG; ILEUM; INTESTINE INNERVATION; NERVOUS SYSTEM PARAMETERS; NEURONAL HYPEREXCITABILITY; PROTEIN ANALYSIS; PROTEIN FUNCTION; RECEPTOR UPREGULATION; SIMONSEN GUINEA PIG;

ANIMALS; CELL DEGRANULATION; ELECTROPHYSIOLOGY; GUINEA PIGS; ILEUM; IMMUNOHISTOCHEMISTRY; LACTOGLOBULINS; MAST CELLS; NEURONS; OLIGOPEPTIDES; RECEPTOR, PAR-2; RECEPTORS, THROMBIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERINE ENDOPEPTIDASES; SUBMUCOUS PLEXUS; SYNAPSES; TISSUE DISTRIBUTION; TRYPSIN; TRYPTASES; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0037335786     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.032011     Document Type: Review

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