Neurotransmitter coding of enteric neurones in the submucous plexus is changed in non-inflamed rectum of patients with Crohn's disease

Neurogastroenterology and Motility

Volumn 13, Issue 3, 2001, Pages 255-264

  Schneider, J ^a   Jehle, E C ^a   Starlinger, M J ^a   Neunlist, M ^a   Michel, K ^a   Hoppe, S ^a   Schemann, M ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Crohn's disease; Enteric nervous system; Human; Neurochemical code; Transmitters

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CHOLINE ACETYLTRANSFERASE; ENOLASE; NITRIC OXIDE SYNTHASE; VASOACTIVE INTESTINAL POLYPEPTIDE;

ADULT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CELL POPULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; FEMALE; HUMAN; HUMAN TISSUE; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTESTINE INNERVATION; MALE; MYENTERIC PLEXUS; NEUROTRANSMISSION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RECTUM;

ADOLESCENT; ADULT; AGED; BIOPSY; CALCITONIN GENE-RELATED PEPTIDE; CHOLINE O-ACETYLTRANSFERASE; COLITIS; CROHN DISEASE; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEURONS; NITRIC OXIDE SYNTHASE; PHOSPHOPYRUVATE HYDRATASE; RECTUM; SUBMUCOUS PLEXUS; SUBSTANCE P; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0035010386     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2982.2001.00265.x     Document Type: Article

References (41)

1. Structural abnormalities of the nervous system in Crohn's disease and ulcerative colitis
2. Slow transit chronic constipation (Arbuthnot Lane's disease). An immunohistochemical study of neuropeptide-containing nerves in resected specimens from the large bowel
3. Changes in neuropeptide-containing nerves in human colonic mucosa with inflammatory bowel disease
4. Colonic vasoactive intestinal peptide nerves in inflammatory bowel disease
5. Neuropeptides and inflammatory bowel disease
6. Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis
7. Enteric neuropathophysiology and inflammatory bowel disease
8. Peptide-containing nerve fibres in the gut wall in Crohn's disease
9. Receptors for sensory neuropeptides in human inflammatory diseases: Implications for the effector role of sensory neurons
10. Vasoactive intestinal polypeptide receptor binding sites in the human gastrointestinal tract: Localization by autoradiography
11. Neurochemical coding in the small intestine of patients with Crohn's disease
12. Nerve remodelling during intestinal inflammation
13. Rectal afferent function in patients with inflammatory and functional intestinal disorders
14. Evidence of impaired rectal sensitivity in patients with Crohn's disease
15. Vasoactive intestinal peptide concentrations and immunocytochemical studies in rectal biopsies from patients with inflammatory bowel disease
16. Neurochemical classification of myenteric neurons in the guinea-pig ileum
17. Neurochemical coding of enteric neurons in the guinea-pig stomach
18. Ontogeny of peptide-containing neurons in human gut - An immunocytochemical study
19. The neurochemical coding and projections of circular muscle motor neurons in the human colon
20. The polarity of neurochemically defined myenteric neurons in the human colon
21. The morphology and projections of retrogradely labeled myenteric neurons in the human intestine
22. Projections of nitric oxide synthase and vasoactive intestinal polypeptide-reactive submucosal neurons in the human colon
23. Identification of cholinergic neurons in enteric nervous system by antibodies against choline acetyltransferase
24. Choline acetyltransferase immunoreactivity in the human small and large intestine
25. Polarised enteric submucosal circuits involved in secretory responses of the guinea-pig proximal colon
26. Polarised innervation pattern of the mucosa of the guinea pig distal colon
27. Mucosal projections of enteric neurons in the porcine small intestine
28. Identification and stimulation by serotonin of intrinsic sensory of the submucosal plexus of the guinea pig gut: Activity-induced expression of Fos immunoreactivity
29. Calcitonin gene-related peptide-like immunoreactivity in the human small intestine
30. Differentiation between Crohn's disease and other inflammatory conditions by electron microscopy
31. Vascular control in colon and rectum
32. Cholinergic and noncholinergic submucosal neurons dilate arterioles in guinea pig colon
33. Vasoactive intestinal polypeptide modulates the in vitro immunoglobulin A production by intestinal lamina propria lymphocytes
34. Gastrointestinal neuropeptides suppress human colonic lamina propria lymphocyte DNA synthesis
35. Direct morphological evidence of neuroimmunomodulation in colonic mucosa of patients with Crohn's disease
36. Neuroenteric peptides affect natural killer activity by intestinal lamina propria mononuclear cells
37. Human gut mucosal mast cells: Ultrastructural observations and anatomic variation in mast cell-nerve associations in vivo
38. Trefoil peptide expression and secretion is regulated by neuropeptides and acetylcholine
39. Irradiation induces marked immunohistochemical expression of vasoactive intestinal peptide in colonic mucosa of man
40. Motor response of the human isolated colon to capsaicin and its relationship to release of vasoactive intestinal polypeptide
41. Release of VIP- but not CGRP-like immunoreactivity by capsaicin from the human isolated small intestine