-
2
-
-
0029830209
-
Tumor necrosis factor alpha (TNF-α): The good, the bad and the potentially very effective
-
Barbara JA, Van Ostade X, Lopez A (1996) Tumor necrosis factor alpha (TNF-α): the good, the bad and the potentially very effective. Immunol Cell Biol 75:434-443
-
(1996)
Immunol Cell Biol
, vol.75
, pp. 434-443
-
-
Barbara, J.A.1
Van Ostade, X.2
Lopez, A.3
-
3
-
-
0026771135
-
Tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β)
-
Riddle NH (1992) Tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β). Curr Opin Immunol 4:327-332
-
(1992)
Curr Opin Immunol
, vol.4
, pp. 327-332
-
-
Riddle, N.H.1
-
4
-
-
0000264230
-
Increased mucosal TNF-α levels and numbers of TNF-α producing cells are unique to Crohn's disease mucosal inflammation
-
Plevy SE, Targan SR, Deem RL, Toyoda H (1995) Increased mucosal TNF-α levels and numbers of TNF-α producing cells are unique to Crohn's disease mucosal inflammation. Gastroenterology 106:A754
-
(1995)
Gastroenterology
, vol.106
-
-
Plevy, S.E.1
Targan, S.R.2
Deem, R.L.3
Toyoda, H.4
-
5
-
-
0028236232
-
Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease
-
Breese EJ, Michie CA, Nicholls SW, Murch SH, Williams CB, Domizio P, Walker-Smith JA, McDonald TT (1994) Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 106: 1455-1466
-
(1994)
Gastroenterology
, vol.106
, pp. 1455-1466
-
-
Breese, E.J.1
Michie, C.A.2
Nicholls, S.W.3
Murch, S.H.4
Williams, C.B.5
Domizio, P.6
Walker-Smith, J.A.7
McDonald, T.T.8
-
6
-
-
0026531017
-
Tumor necrosis factor alpha in stool as a marker of intestinal inflammation
-
Braegger CP, Nicholls S, Murch SH, Stephens S, MacDonald TT (1992) Tumor necrosis factor alpha in stool as a marker of intestinal inflammation. Lancet 339:89-91
-
(1992)
Lancet
, vol.339
, pp. 89-91
-
-
Braegger, C.P.1
Nicholls, S.2
Murch, S.H.3
Stephens, S.4
MacDonald, T.T.5
-
7
-
-
0027486125
-
Location of tumor necrosis factor α by immunohistochemistry in chronic inflammatory bowel disease
-
Murch SH, Braegger CP, Walker-Smith JA, MacDonald TT (1993) Location of tumor necrosis factor α by immunohistochemistry in chronic inflammatory bowel disease. Gut 34: 1705-1709
-
(1993)
Gut
, vol.34
, pp. 1705-1709
-
-
Murch, S.H.1
Braegger, C.P.2
Walker-Smith, J.A.3
MacDonald, T.T.4
-
8
-
-
0028038782
-
Inflammatory granuloma formation is mediated by tnf-α inducible intercellular adhesion molecule-1
-
Lukacs NW, Chensue SW, Strieter R, Warmington K, Kunkel SL (1994) Inflammatory granuloma formation is mediated by TNF-α inducible intercellular adhesion molecule-1. J Immunol 152:5883-5889
-
(1994)
J Immunol
, vol.152
, pp. 5883-5889
-
-
Lukacs, N.W.1
Chensue, S.W.2
Strieter, R.3
Warmington, K.4
Kunkel, S.L.5
-
9
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumour necrosis factor alpha from cells
-
Black RA, Rauch CT, Kozlosky CJ, et al (1997) A metalloproteinase disintegrin that releases tumour necrosis factor alpha from cells. Nature 385:729-733
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
-
10
-
-
8044250278
-
Cloning of a desintegrin metalloproteinase that processes precursor tumour necrosis factor alpha
-
Moss ML, Jin SL, Milla ME, et al (1997) Cloning of a desintegrin metalloproteinase that processes precursor tumour necrosis factor alpha. Nature 385:733-736
-
(1997)
Nature
, vol.385
, pp. 733-736
-
-
Moss, M.L.1
Jin, S.L.2
Milla, M.E.3
-
11
-
-
0031853981
-
Secretion imbalance between tumor necrosis factor and its inhibitor in inflammatory bowel disease
-
Noguchi M, Hiwatashi N, Liu Z, Toyota T (1998) Secretion imbalance between tumor necrosis factor and its inhibitor in inflammatory bowel disease. Gut 43:203-209
-
(1998)
Gut
, vol.43
, pp. 203-209
-
-
Noguchi, M.1
Hiwatashi, N.2
Liu, Z.3
Toyota, T.4
-
12
-
-
0029836444
-
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF kappa beta abrogates established experimental colitis in mice
-
Neurath MF, Pettersson S, Meyer zum Buschenfelde KH, Strober W (1996) Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF kappa beta abrogates established experimental colitis in mice. Nat Med 2:998-1004
-
(1996)
Nat Med
, vol.2
, pp. 998-1004
-
-
Neurath, M.F.1
Pettersson, S.2
Meyer Zum Buschenfelde, K.H.3
Strober, W.4
-
13
-
-
0027361432
-
Construction and initial characterization of a mouse-human anti-TNF-antibody
-
Knight DM, Trinh H, Le J, Siegel S, Shealy D, McDonough M, Scallon B, Arevalo Moore M, Vilcek J, Daddona P, Ghrayeb J (1993) Construction and initial characterization of a mouse-human anti-TNF-antibody. Mol Immunol 30: 1443-1453
-
(1993)
Mol Immunol
, vol.30
, pp. 1443-1453
-
-
Knight, D.M.1
Trinh, H.2
Le, J.3
Siegel, S.4
Shealy, D.5
McDonough, M.6
Scallon, B.7
Arevalo Moore, M.8
Vilcek, J.9
Daddona, P.10
Ghrayeb, J.11
-
14
-
-
0028964310
-
The mouse/ human chimeric monoclonal antibody cA2 neutralizes in vitro and protects transgenic mice from cachexia and TNF-α lethality in vivo
-
Siegel SA, Shealy DJ, Nakada MT, Le J, Woulfe DS, Probert L, Kollias G, Ghrayeb J, Vilcek J, Dadonna PE (1995) The mouse/ human chimeric monoclonal antibody cA2 neutralizes in vitro and protects transgenic mice from cachexia and TNF-α lethality in vivo. Cytokine 7:15-25
-
(1995)
Cytokine
, vol.7
, pp. 15-25
-
-
Siegel, S.A.1
Shealy, D.J.2
Nakada, M.T.3
Le, J.4
Woulfe, D.S.5
Probert, L.6
Kollias, G.7
Ghrayeb, J.8
Vilcek, J.9
Dadonna, P.E.10
-
15
-
-
0029004771
-
Chimeric anti-TNF-α monoclonal antibody cA2 binds recombinant transmembrane TNF-α and activates immune effector functions
-
Scallon BJ, Moore MA, Trinh H, Knight DM, Ghrayeb J (1995) Chimeric anti-TNF-α monoclonal antibody cA2 binds recombinant transmembrane TNF-α and activates immune effector functions. Cytokine 7:251-259
-
(1995)
Cytokine
, vol.7
, pp. 251-259
-
-
Scallon, B.J.1
Moore, M.A.2
Trinh, H.3
Knight, D.M.4
Ghrayeb, J.5
-
16
-
-
0029900295
-
The tumor necrosis factor ligand and receptor families
-
Bazzoni F, Beutler B (1996) The tumor necrosis factor ligand and receptor families. New Engl J Med 334: 1717-1725
-
(1996)
New Engl J Med
, vol.334
, pp. 1717-1725
-
-
Bazzoni, F.1
Beutler, B.2
-
17
-
-
0027198002
-
Soluble tumor necrosis factor alpha (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneous-ly as both TNF carriers and TNF antagonists
-
Mohler KM, Torrance DS, Smith CA, et al (1993) Soluble tumor necrosis factor alpha (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneous-ly as both TNF carriers and TNF antagonists. J Immunol 151 : 1548-1561
-
(1993)
J Immunol
, vol.151
, pp. 1548-1561
-
-
Mohler, K.M.1
Torrance, D.S.2
Smith, C.A.3
-
18
-
-
0030925172
-
Treatment with tumour necrosis factor inhibitor oxpentifylline does not improve corticosteroid dependant chronic active Crohn's disease
-
Bauditz J, Haemling J, Ortner M, Lochs H, Raedler A, Schreiber S (1997) Treatment with tumour necrosis factor inhibitor oxpentifylline does not improve corticosteroid dependant chronic active Crohn's disease. Gut 40:470-474
-
(1997)
Gut
, vol.40
, pp. 470-474
-
-
Bauditz, J.1
Haemling, J.2
Ortner, M.3
Lochs, H.4
Raedler, A.5
Schreiber, S.6
-
19
-
-
0031583764
-
Thalidomide in Crohn's disease
-
Wettstein AR, Meagher AP (1997) Thalidomide in Crohn's disease. Lancet 350:1445-1446
-
(1997)
Lancet
, vol.350
, pp. 1445-1446
-
-
Wettstein, A.R.1
Meagher, A.P.2
-
20
-
-
0030859308
-
Thalidomide in oral Crohn's disease refractory to conventional medical treatment
-
Odeka EB, Miller V (1997) Thalidomide in oral Crohn's disease refractory to conventional medical treatment. J Pediatr Gastroenterol Nutr 25:250-251
-
(1997)
J Pediatr Gastroenterol Nutr
, vol.25
, pp. 250-251
-
-
Odeka, E.B.1
Miller, V.2
-
21
-
-
0029050742
-
Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)
-
Van Dullemen HM, van Deventer SJH, Hommes DW, Bijl HA, Jansen J, Tytgat GNJ, Woody J (1995) Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2). Gastroenterology 109: 129-135
-
(1995)
Gastroenterology
, vol.109
, pp. 129-135
-
-
Van Dullemen, H.M.1
Van Deventer, S.J.H.2
Hommes, D.W.3
Bijl, H.A.4
Jansen, J.5
Tytgat, G.N.J.6
Woody, J.7
-
22
-
-
0000493124
-
A multicenter trial of cA2 anti TNF chimeric monoclonal antibody in patients with active Crohn's disease
-
McCabe RP, Woody J, van Deventer SJH, Targan SR, et al (1996) A multicenter trial of cA2 anti TNF chimeric monoclonal antibody in patients with active Crohn's disease. Gastroenterology 110:A962
-
(1996)
Gastroenterology
, vol.110
-
-
McCabe, R.P.1
Woody, J.2
Van Deventer, S.J.H.3
Targan, S.R.4
-
23
-
-
0030954732
-
A short term study of chimeric monoclonal antibody (cA2) to tumor necrosis factor α for Crohn's disease
-
Targan SR, Hanauer SB, van Deventer SJH, Mayer L, Present DH, Braakman T, DeWoody KL, Schaible TF, Rutgeerts PJ (1997) A short term study of chimeric monoclonal antibody (cA2) to tumor necrosis factor α for Crohn's disease. N Engl J Med 337: 1029-1035
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.H.3
Mayer, L.4
Present, D.H.5
Braakman, T.6
DeWoody, K.L.7
Schaible, T.F.8
Rutgeerts, P.J.9
-
24
-
-
0001311756
-
Retreatment with anti-TNF-α chimeric antibody effectively maintains cA2-induced remission in Crohn's disease
-
Rutgeerts P, D'Haens G, van Deventer SJH, Present DH, Mayer L, Hanauer SB, Braakman TAJ, DeWoody KL, Schaible TF, Targan SR (1997) Retreatment with anti-TNF-α chimeric antibody effectively maintains cA2-induced remission in Crohn's disease. Gastroenterology 112:A1078
-
(1997)
Gastroenterology
, vol.112
-
-
Rutgeerts, P.1
D'Haens, G.2
Van Deventer, S.J.H.3
Present, D.H.4
Mayer, L.5
Hanauer, S.B.6
Braakman, T.A.J.7
DeWoody, K.L.8
Schaible, T.F.9
Targan, S.R.10
-
25
-
-
0002454303
-
Controlled study of anti TNF α treatment for enterocutaneous fistulae complicating Crohn's disease
-
abstract no 01.11
-
Van Hogezand RA, van Deventer SJH, Present D, et al (1997) Controlled study of anti TNF α treatment for enterocutaneous fistulae complicating Crohn's disease. Gut 41 [Suppl 3]: A2, abstract no 01.11
-
(1997)
Gut
, vol.41
, Issue.SUPPL. 3
-
-
Van Hogezand, R.A.1
Van Deventer, S.J.H.2
Present, D.3
-
26
-
-
0345564526
-
Anti TNF α monoclonal antibody (cA2) produces endoscopic healing in patients with treatment resistant active Crohn's disease
-
D'Haens G, van Deventer S, van Hogezand R, Chalmers, et al (1998) Anti TNF α monoclonal antibody (cA2) produces endoscopic healing in patients with treatment resistant active Crohn's disease. Gastroenterology 114:A964
-
(1998)
Gastroenterology
, vol.114
-
-
D'Haens, G.1
Van Deventer, S.2
Van Hogezand, R.3
Chalmers4
-
27
-
-
0032923705
-
Tumor necrosis factor α antibody (infliximab) therapy profoundly downregulates the inflammation in Crohn's ileocolitis
-
in press
-
Baert FJ, D'Haens GR, Peeters M, Hiele MI, Shaible TF, Shealy D, Geboes K, Rutgeerts PR (1999) Tumor necrosis factor α antibody (infliximab) therapy profoundly downregulates the inflammation in Crohn's ileocolitis. Gastroenterology 116 (in press)
-
(1999)
Gastroenterology
, pp. 116
-
-
Baert, F.J.1
D'Haens, G.R.2
Peeters, M.3
Hiele, M.I.4
Shaible, T.F.5
Shealy, D.6
Geboes, K.7
Rutgeerts, P.R.8
-
28
-
-
0031043778
-
Randomised controlled trial of CDP571 antibody to tumour necrosis factor alpha in Crohn's disease
-
Stack WA, Mann SD, Heath P, et al (1997) Randomised controlled trial of CDP571 antibody to tumour necrosis factor alpha in Crohn's disease. Lancet 349:521-524
-
(1997)
Lancet
, vol.349
, pp. 521-524
-
-
Stack, W.A.1
Mann, S.D.2
Heath, P.3
-
29
-
-
0013511183
-
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
-
Moreland LW, Baumgartner SW, Schiff MH, et al (1997) Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 337:141-147
-
(1997)
N Engl J Med
, vol.337
, pp. 141-147
-
-
Moreland, L.W.1
Baumgartner, S.W.2
Schiff, M.H.3
|