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Volumn 17, Issue 8, 2007, Pages 889-907

Enhanced selective serotonin re-uptake inhibitors as antidepressants: 2004-2006

Author keywords

5 HT1A; 5 HT1B; Antidepressant; Depression; Neurokinin receptor; NK1 antagonist; Noradrenaline re uptake inhibitor; Selective serotonin re uptake inhibitor; Serotonin transporter; Substance P

Indexed keywords

3 AMINO 1 ARYLPROPYLINDOLE DERIVATIVE; 3 AMINOCHROMAN DERIVATIVE; 3 AMINOPYRROLIDINE DERIVATIVE; 3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; ANTIDEPRESSANT AGENT; BENZODIOXAN DERIVATIVE; BENZOFURANYLPIPERAZINEQUINOLINE DERIVATIVE; BENZOTHIENYLPIPERAZINEQUINOLINE DERIVATIVE; BETA LACTAM DERIVATIVE; CITALOPRAM; DIAZACYCLOOCTANE DERIVATIVE; DULOXETINE; GLYCINAMIDE; IMIPRAMINE; INDOLALKYLPIPERAZINE DERIVATIVE; MONOAMINE REUPTAKE INHIBITOR; MORPHOLINE DERIVATIVE; N PYRROLIDIN 3 YLAMIDE DERIVATIVE; NEUROKININ 1 RECEPTOR ANTAGONIST; NISOXETINE; PYROVALERONE DERIVATIVE; PYRROLIDINEAMINE DERIVATIVE; QUINOLINE 3 AMINOCHROMAN DERIVATIVE; REBOXETINE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1B ANTAGONIST; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VENLAFAXINE;

EID: 34548295512     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.17.8.889     Document Type: Review
Times cited : (9)

References (106)
  • 1
    • 33749057523 scopus 로고    scopus 로고
    • Prevalence and effects of mood disorders on work performance in a nationally representative sample of US workers
    • KESSLER RC, AKISKAL HS, AMES M et al.: Prevalence and effects of mood disorders on work performance in a nationally representative sample of US workers. Am. J. Psychiatry (2006) 163(9):1561-1568.
    • (2006) Am. J. Psychiatry , vol.163 , Issue.9 , pp. 1561-1568
    • KESSLER, R.C.1    AKISKAL, H.S.2    AMES, M.3
  • 3
    • 0037641074 scopus 로고    scopus 로고
    • The epidemiology of major depressive episodes: Results from the International Consortium of Psychiatric Epidemiology (ICPE) Surveys
    • ANDRADE L, CARAVEO-ANDUAGA JJ, BERGLUND P et al.: The epidemiology of major depressive episodes: results from the International Consortium of Psychiatric Epidemiology (ICPE) Surveys. Int. J. Methods Psychiatry Res. (2003) 12(1):3-21.
    • (2003) Int. J. Methods Psychiatry Res , vol.12 , Issue.1 , pp. 3-21
    • ANDRADE, L.1    CARAVEO-ANDUAGA, J.J.2    BERGLUND, P.3
  • 4
    • 0037831023 scopus 로고    scopus 로고
    • The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R)
    • KESSLER RC, BERGLUND P, DEMLER O et al.: The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA (2003) 289(23):3095-3105.
    • (2003) JAMA , vol.289 , Issue.23 , pp. 3095-3105
    • KESSLER, R.C.1    BERGLUND, P.2    DEMLER, O.3
  • 5
    • 0028156958 scopus 로고
    • Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey
    • KESSLER RC, MCGONAGLE KA, ZHAO S et al.: Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch. Gen. Psychiatry (1994) 51(1):8-19.
    • (1994) Arch. Gen. Psychiatry , vol.51 , Issue.1 , pp. 8-19
    • KESSLER, R.C.1    MCGONAGLE, K.A.2    ZHAO, S.3
  • 6
    • 0037493499 scopus 로고    scopus 로고
    • Cost of lost productive work time among US workers with depression
    • STEWART WF, RICCI JA, CHEE E, HAHN SR, MORGANSTEIN D: Cost of lost productive work time among US workers with depression. JAMA (2003) 289(23):3135-3144.
    • (2003) JAMA , vol.289 , Issue.23 , pp. 3135-3144
    • STEWART, W.F.1    RICCI, J.A.2    CHEE, E.3    HAHN, S.R.4    MORGANSTEIN, D.5
  • 7
    • 17144398877 scopus 로고    scopus 로고
    • The economic burden of depression in the US: Societal and patient perspectives
    • GREENBERG PE, BIRNBAUM HG: The economic burden of depression in the US: societal and patient perspectives. Expert Opin. Pharmacother. (2005) 6(3):369-376.
    • (2005) Expert Opin. Pharmacother , vol.6 , Issue.3 , pp. 369-376
    • GREENBERG, P.E.1    BIRNBAUM, H.G.2
  • 8
    • 1242338645 scopus 로고    scopus 로고
    • The economic burden of depression in the United States: How did it change between 1990 and 2000?
    • GREENBERG PE, KESSLER RC, BIRNBAUM HG et al.: The economic burden of depression in the United States: how did it change between 1990 and 2000? J. Clin. Psychiatry (2003) 64(12):1465-1475.
    • (2003) J. Clin. Psychiatry , vol.64 , Issue.12 , pp. 1465-1475
    • GREENBERG, P.E.1    KESSLER, R.C.2    BIRNBAUM, H.G.3
  • 9
    • 0028294525 scopus 로고
    • Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs)
    • HYTTEL J: Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs). Int. Clin. Pychopharmacol. (1994) 9(Suppl. 1):19-26.
    • (1994) Int. Clin. Pychopharmacol , vol.9 , Issue.SUPPL. 1 , pp. 19-26
    • HYTTEL, J.1
  • 10
    • 0027163303 scopus 로고
    • 5-HT and antidepressants: New views from microdialysis studies
    • ARTIGAS F: 5-HT and antidepressants: new views from microdialysis studies. Trends Pharmacol. Sci. (1993) 14(7):262.
    • (1993) Trends Pharmacol. Sci , vol.14 , Issue.7 , pp. 262
    • ARTIGAS, F.1
  • 11
    • 0034232069 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors: A review of efficacy and tolerability in depression
    • MACE S, TAYLOR D: Selective serotonin reuptake inhibitors: a review of efficacy and tolerability in depression. Expert Opin. Pharmacother. (2000) 1(5):917-933.
    • (2000) Expert Opin. Pharmacother , vol.1 , Issue.5 , pp. 917-933
    • MACE, S.1    TAYLOR, D.2
  • 12
    • 0031690668 scopus 로고    scopus 로고
    • New approaches to rapid onset antidepressants
    • BRINER K, DODEL RC: New approaches to rapid onset antidepressants. Curr. Pharm. Des. (1998) 4(4):291-302.
    • (1998) Curr. Pharm. Des , vol.4 , Issue.4 , pp. 291-302
    • BRINER, K.1    DODEL, R.C.2
  • 13
    • 0032958811 scopus 로고    scopus 로고
    • Effects of SSRIs on sexual function: A critical review
    • ROSEN RC, LANE RM, MENZA M: Effects of SSRIs on sexual function: a critical review. J. Clin. Pychopharmacol. (1999) 19(1):67-85.
    • (1999) J. Clin. Pychopharmacol , vol.19 , Issue.1 , pp. 67-85
    • ROSEN, R.C.1    LANE, R.M.2    MENZA, M.3
  • 15
    • 34547445666 scopus 로고    scopus 로고
    • Mechanism of action of antidepressants
    • ARTIGAS F, NUTT DJ, SHELTON R: Mechanism of action of antidepressants. Psychapharmacol. Bull. (2002) 36(Suppl. 2):123-132.
    • (2002) Psychapharmacol. Bull , vol.36 , Issue.SUPPL. 2 , pp. 123-132
    • ARTIGAS, F.1    NUTT, D.J.2    SHELTON, R.3
  • 16
    • 18844370877 scopus 로고    scopus 로고
    • The dual transporter inhibitor duloxetine: A review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression
    • BYMASTER FP, LEE TC, KNADLER MP, DETKE MJ, IYENGAR S: The dual transporter inhibitor duloxetine: a review of its preclinical pharmacology, pharmacokinetic profile, and clinical results in depression. Curr. Pharm. Des. (2005) 11(12):1475-1493.
    • (2005) Curr. Pharm. Des , vol.11 , Issue.12 , pp. 1475-1493
    • BYMASTER, F.P.1    LEE, T.C.2    KNADLER, M.P.3    DETKE, M.J.4    IYENGAR, S.5
  • 17
    • 21244493207 scopus 로고    scopus 로고
    • Venlafaxine XR demonstrates higher rates of sustained remission compared to fluoxetine, paroxetine or placebo
    • SHELTON C, ENTSUAH R, PADMANABHAN SK, VINALL PE: Venlafaxine XR demonstrates higher rates of sustained remission compared to fluoxetine, paroxetine or placebo. Int. Clin. Pychopharmacol. (2005) 20(4):233-238.
    • (2005) Int. Clin. Pychopharmacol , vol.20 , Issue.4 , pp. 233-238
    • SHELTON, C.1    ENTSUAH, R.2    PADMANABHAN, S.K.3    VINALL, P.E.4
  • 18
    • 19944432573 scopus 로고    scopus 로고
    • Discovery and structure-activity relationships of novel selective norepinephrine and dual serotonin/ norepinephrine reuptake inhibitors
    • BOOT J, CASES M, CLARK BP et al.: Discovery and structure-activity relationships of novel selective norepinephrine and dual serotonin/ norepinephrine reuptake inhibitors. Bioorg. Med. Chem. Lett. (2005) 15(3):699-703.
    • (2005) Bioorg. Med. Chem. Lett , vol.15 , Issue.3 , pp. 699-703
    • BOOT, J.1    CASES, M.2    CLARK, B.P.3
  • 19
    • 33645845143 scopus 로고    scopus 로고
    • N-Alkyl-N-arylmethylpiperidin-4-amines: Novel dual inhibitors of serotonin and norepinephrine reuptake
    • BOOT JR, BOULET SL, CLARK BP et al.: N-Alkyl-N-arylmethylpiperidin-4-amines: novel dual inhibitors of serotonin and norepinephrine reuptake. Bioorg. Med. Chem. Lett. (2006) 16(10):2714-2718.
    • (2006) Bioorg. Med. Chem. Lett , vol.16 , Issue.10 , pp. 2714-2718
    • BOOT, J.R.1    BOULET, S.L.2    CLARK, B.P.3
  • 20
    • 5344232075 scopus 로고    scopus 로고
    • Benzothienyloxy phenylpropanamines, novel dual inhibitors of serotonin and norepinephrine reuptake
    • BOOT JR, BRACE G, DELATOUR CL et al.: Benzothienyloxy phenylpropanamines, novel dual inhibitors of serotonin and norepinephrine reuptake. Bioorg. Med. Chem. Lett. (2004) 14(21):5395-5399.
    • (2004) Bioorg. Med. Chem. Lett , vol.14 , Issue.21 , pp. 5395-5399
    • BOOT, J.R.1    BRACE, G.2    DELATOUR, C.L.3
  • 21
    • 33847732615 scopus 로고    scopus 로고
    • N-Benzyl-N-(tetrahydro-2H-pyran-4-yl) pyrrolidin-3-amines as selective dual serotonin/noradrenaline re-uptake inhibitors
    • FISH PV, FRAY MJ, STOBIE A, WAKENHUT F, WHITLOCK GA: N-Benzyl-N-(tetrahydro-2H-pyran-4-yl) pyrrolidin-3-amines as selective dual serotonin/noradrenaline re-uptake inhibitors. Bioorg. Med. Chem. Lett. (2007) 17(7):2022-2025.
    • (2007) Bioorg. Med. Chem. Lett , vol.17 , Issue.7 , pp. 2022-2025
    • FISH, P.V.1    FRAY, M.J.2    STOBIE, A.3    WAKENHUT, F.4    WHITLOCK, G.A.5
  • 22
    • 33745727155 scopus 로고    scopus 로고
    • N-(1,2-diphenylethyl)piperazines: A new class of dual serotonin/ noradrenaline reuptake inhibitor
    • FRAY MJ, BISH G, BROWN AD et al.: N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/ noradrenaline reuptake inhibitor. Bioorg. Med. Chem. Lett. (2006) 16(16):4345-4348.
    • (2006) Bioorg. Med. Chem. Lett , vol.16 , Issue.16 , pp. 4345-4348
    • FRAY, M.J.1    BISH, G.2    BROWN, A.D.3
  • 23
    • 33745781487 scopus 로고    scopus 로고
    • Structure-activity relationships of N-substituted piperazine amine reuptake inhibitors
    • FRAY MJ, BISH G, FISH PV et al.: Structure-activity relationships of N-substituted piperazine amine reuptake inhibitors. Biborg. Med. Chem. Lett. (2006) 16(16):4349-4353.
    • (2006) Biborg. Med. Chem. Lett , vol.16 , Issue.16 , pp. 4349-4353
    • FRAY, M.J.1    BISH, G.2    FISH, P.V.3
  • 24
    • 0344118707 scopus 로고    scopus 로고
    • Syntheses and binding studies of new [(aryl)(aryloxy)methyl]-piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters
    • ORJALES A, MOSQUERA R, TOLEDO A et al.: Syntheses and binding studies of new [(aryl)(aryloxy)methyl]-piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters. J. Med. Chem. (2003) 46(25):5512-5532.
    • (2003) J. Med. Chem , vol.46 , Issue.25 , pp. 5512-5532
    • ORJALES, A.1    MOSQUERA, R.2    TOLEDO, A.3
  • 25
    • 0032440963 scopus 로고    scopus 로고
    • Mechanism of action of serotonin selective reuptake inhibitors. Serotonin receptors and pathways mediate therapeutic effects and side effects
    • STAHL SM: Mechanism of action of serotonin selective reuptake inhibitors. Serotonin receptors and pathways mediate therapeutic effects and side effects. J. Affect. Disord. (1998) 51(3):215-235.
    • (1998) J. Affect. Disord , vol.51 , Issue.3 , pp. 215-235
    • STAHL, S.M.1
  • 29
    • 17544368021 scopus 로고    scopus 로고
    • Strategies for producing faster acting antidepressants
    • ADELL A, CASTRO E, CELADA P et al.: Strategies for producing faster acting antidepressants. Drug Discov. Today (2005) 10(8):578-585.
    • (2005) Drug Discov. Today , vol.10 , Issue.8 , pp. 578-585
    • ADELL, A.1    CASTRO, E.2    CELADA, P.3
  • 30
    • 33644854626 scopus 로고    scopus 로고
    • Pindolol augmentation of antidepressant response
    • ARTIGAS F, ADELL A, CELADA P: Pindolol augmentation of antidepressant response. Curr. Drug Targets (2006) 7(2):139-147.
    • (2006) Curr. Drug Targets , vol.7 , Issue.2 , pp. 139-147
    • ARTIGAS, F.1    ADELL, A.2    CELADA, P.3
  • 31
    • 0028218177 scopus 로고
    • Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors
    • ARTIGAS F, PEREZ V, ALVAREZ E: Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors. Arch. Gen. Psychiatry (1994) 51(3):248-251.
    • (1994) Arch. Gen. Psychiatry , vol.51 , Issue.3 , pp. 248-251
    • ARTIGAS, F.1    PEREZ, V.2    ALVAREZ, E.3
  • 32
    • 0342894667 scopus 로고    scopus 로고
    • Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment
    • PEREZ V, GILABERTE I, FARIES D, ALVAREZ E, ARTIGAS F: Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment. Lancet (1997) 349(9065):1594-1597.
    • (1997) Lancet , vol.349 , Issue.9065 , pp. 1594-1597
    • PEREZ, V.1    GILABERTE, I.2    FARIES, D.3    ALVAREZ, E.4    ARTIGAS, F.5
  • 34
    • 0035191933 scopus 로고    scopus 로고
    • Pindolol augmentation of selective serotonin reuptake inhibitors: PET evidence that the dose used in clinical trials is too low
    • RABINER EA, BRAGWAGAR Z, GUNN RN et al.: Pindolol augmentation of selective serotonin reuptake inhibitors: PET evidence that the dose used in clinical trials is too low. Am. J. Psychiatry (2001) 158(12):2080-2082.
    • (2001) Am. J. Psychiatry , vol.158 , Issue.12 , pp. 2080-2082
    • RABINER, E.A.1    BRAGWAGAR, Z.2    GUNN, R.N.3
  • 35
    • 1542374714 scopus 로고    scopus 로고
    • Once-daily high-dose pindolol for SSRI-refractory depression
    • SOKOLSKI KN, CONNEY JC, BROWN BJ, DEMET EM: Once-daily high-dose pindolol for SSRI-refractory depression. Psychiatry Res. (2004) 125(2):81-86.
    • (2004) Psychiatry Res , vol.125 , Issue.2 , pp. 81-86
    • SOKOLSKI, K.N.1    CONNEY, J.C.2    BROWN, B.J.3    DEMET, E.M.4
  • 44
    • 0034959682 scopus 로고    scopus 로고
    • Pharmacology of rapid-onset antidepressant treatment strategies
    • BLIER P: Pharmacology of rapid-onset antidepressant treatment strategies. J. Clin. Psychiatry (2001) 62(Suppl. 15):12-17.
    • (2001) J. Clin. Psychiatry , vol.62 , Issue.SUPPL. 15 , pp. 12-17
    • BLIER, P.1
  • 45
    • 0034123688 scopus 로고    scopus 로고
    • Serotonin autoreceptor function and antidepressant drug action
    • HJORTH S, BENGTSSON HJ, KULLBERG A et al.: Serotonin autoreceptor function and antidepressant drug action. J. Psychopharmacol. (2000) 14(2):177-185.
    • (2000) J. Psychopharmacol , vol.14 , Issue.2 , pp. 177-185
    • HJORTH, S.1    BENGTSSON, H.J.2    KULLBERG, A.3
  • 46
    • 7344239900 scopus 로고    scopus 로고
    • 1B receptor antagonist with negative intrinsic activity
    • 1B receptor antagonist with negative intrinsic activity. Br. J. Pharmacol. (1998) 125(1):202-208.
    • (1998) Br. J. Pharmacol , vol.125 , Issue.1 , pp. 202-208
    • SELKIRK, J.V.1    SCOTT, C.2    HO, M.3
  • 47
    • 33747081967 scopus 로고    scopus 로고
    • 1B receptor antagonist SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2, 3-dihydro-5-methoxyindol-1-yl]-1-[2′-methyl-4′-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): In vivo neurochemical and behavioural evidence of anxiolytic/antidepressant activity
    • 1B receptor antagonist SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2, 3-dihydro-5-methoxyindol-1-yl]-1-[2′-methyl-4′-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): in vivo neurochemical and behavioural evidence of anxiolytic/antidepressant activity. Neuropharmacology (2006) 50(8):975-983.
    • (2006) Neuropharmacology , vol.50 , Issue.8 , pp. 975-983
    • DAWSON, L.A.1    HUGHES, Z.A.2    STARR, K.R.3
  • 48
    • 0036598034 scopus 로고    scopus 로고
    • 1B/1D receptor antagonists and agonists and their potential therapeutic applications
    • 1B/1D receptor antagonists and agonists and their potential therapeutic applications. Curr. Top Med. Chem. (2002) 2(6):559-574.
    • (2002) Curr. Top Med. Chem , vol.2 , Issue.6 , pp. 559-574
    • SLASSI, A.1
  • 49
    • 0035891887 scopus 로고    scopus 로고
    • Ligands for the investigation of 5-HT autoreceptor function
    • ROBERTS C, PRICE GW, MIDDLEMISS DN: Ligands for the investigation of 5-HT autoreceptor function. Brain Res. Bull. (2001) 56(5):463-469.
    • (2001) Brain Res. Bull , vol.56 , Issue.5 , pp. 463-469
    • ROBERTS, C.1    PRICE, G.W.2    MIDDLEMISS, D.N.3
  • 52
    • 0343550410 scopus 로고    scopus 로고
    • 1B/1D antagonists: Chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides
    • 1B/1D antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides. J. Med. Chem. (2000) 43(3):517-525.
    • (2000) J. Med. Chem , vol.43 , Issue.3 , pp. 517-525
    • LIAO, Y.1    BOTTCHER, H.2    HARTING, J.3
  • 53
    • 0029823246 scopus 로고    scopus 로고
    • 1D antagonist and a 5-HT reuptake inhibitor synergistically, Increases 5-HT release in guinea pig hypothalamus in vivo
    • 1D antagonist and a 5-HT reuptake inhibitor synergistically, Increases 5-HT release in guinea pig hypothalamus in vivo. J. Neurochem. (1996) 67(5):2204-2207.
    • (1996) J. Neurochem , vol.67 , Issue.5 , pp. 2204-2207
    • ROLLEMA, H.1    CLARKE, T.2    SPROUSE, J.S.3    SCHULZ, D.W.4
  • 54
    • 0030843655 scopus 로고    scopus 로고
    • 1B/1D antagonists with paroxetine on serotonin efflux in rat ventral lateral geniculate nucleus slices
    • 1B/1D antagonists with paroxetine on serotonin efflux in rat ventral lateral geniculate nucleus slices. Brain Res. Bull. (1997) 43(4):405-409.
    • (1997) Brain Res. Bull , vol.43 , Issue.4 , pp. 405-409
    • DAVIDSON, C.1    STAMFORD, J.A.2
  • 57
    • 0036837312 scopus 로고    scopus 로고
    • 1B autoreceptors in the enhancement of serotonin turnover in the mouse brain following repeated treatment with fluoxetine
    • 1B autoreceptors in the enhancement of serotonin turnover in the mouse brain following repeated treatment with fluoxetine. Life Sci. (2002) 71(24):2867-2880.
    • (2002) Life Sci , vol.71 , Issue.24 , pp. 2867-2880
    • STENFORS, C.1    ROSS, S.B.2
  • 58
    • 0030610866 scopus 로고    scopus 로고
    • 1B receptor selectivity for 5-HT terminal autoreceptor activity: An in vivo microdialysis study in the freely-moving guinea-pig
    • 1B receptor selectivity for 5-HT terminal autoreceptor activity: an in vivo microdialysis study in the freely-moving guinea-pig. Neuropharmacology (1997) 36(4-5):549-557.
    • (1997) Neuropharmacology , vol.36 , Issue.4-5 , pp. 549-557
    • ROBERTS, C.1    PRICE, G.W.2    GASTER, L.3
  • 59
    • 0030981485 scopus 로고    scopus 로고
    • 1B/1D receptors in the modulation of 5-hydroxytryptamine levels in the frontal cortex of the conscious guinea pig
    • 1B/1D receptors in the modulation of 5-hydroxytryptamine levels in the frontal cortex of the conscious guinea pig. Eur. J. Pharmacol. (1997) 326(1):23-30.
    • (1997) Eur. J. Pharmacol , vol.326 , Issue.1 , pp. 23-30
    • ROBERTS, C.1    PRICE, G.W.2    JONES, B.J.3
  • 60
    • 21244456554 scopus 로고    scopus 로고
    • The effect of chronic selective serotonin reuptake inhibitor treatment on serotonin 1B receptor sensitivity and HPA axis activity
    • JONGSMA ME, BOSKER FJ, CREMERS TI, WESTERINK BH, DEN BOER JA: The effect of chronic selective serotonin reuptake inhibitor treatment on serotonin 1B receptor sensitivity and HPA axis activity. Prog. Neuropsychopharmacol. Biol. Psychiatry (2005) 29(5):738-744.
    • (2005) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.29 , Issue.5 , pp. 738-744
    • JONGSMA, M.E.1    BOSKER, F.J.2    CREMERS, T.I.3    WESTERINK, B.H.4    DEN, B.J.5
  • 61
    • 0038519162 scopus 로고    scopus 로고
    • Depression: Emerging research and treatment approaches. 16-17 January 2003, Paris, France
    • MORET C: Depression: emerging research and treatment approaches. 16-17 January 2003, Paris, France. IDrugs (2003) 6(3):183-186.
    • (2003) IDrugs , vol.6 , Issue.3 , pp. 183-186
    • MORET, C.1
  • 62
    • 0034704821 scopus 로고    scopus 로고
    • 1B/1D antagonistic activity: A new approach toward efficient antidepressants
    • 1B/1D antagonistic activity: a new approach toward efficient antidepressants. J. Med. Chem. (2000) 43(6):1149-1157.
    • (2000) J. Med. Chem , vol.43 , Issue.6 , pp. 1149-1157
    • MATZEN, L.1    VAN AMSTERDAM, C.2    RAUTENBERG, W.3
  • 63
    • 11144356460 scopus 로고    scopus 로고
    • 1D antagonist/serotonin reuptake inhibitor lead using rapid parallel synthesis
    • 1D antagonist/serotonin reuptake inhibitor lead using rapid parallel synthesis. Bioorg. Med. Chem. Lett. (2004) 14(10):2469-2472.
    • (2004) Bioorg. Med. Chem. Lett , vol.14 , Issue.10 , pp. 2469-2472
    • TIMMS, G.H.1    BOOT, J.R.2    BROADMORE, R.J.3
  • 64
    • 0032508514 scopus 로고    scopus 로고
    • Distinct mechanism for antidepressant activity by blockade of central substance P receptors
    • KRAMER MS, CUTLER N, FEIGHNER J et al.: Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science (1998) 281(5383):1640-1645.
    • (1998) Science , vol.281 , Issue.5383 , pp. 1640-1645
    • KRAMER, M.S.1    CUTLER, N.2    FEIGHNER, J.3
  • 65
    • 0033900385 scopus 로고    scopus 로고
    • Substance P antagonists: Novel agents in the treatment of depression
    • ARGYROPOULOS SV, NUTT DJ: Substance P antagonists: novel agents in the treatment of depression. Expert Opin. Investig. Drugs (2000) 9(8):1871-1875.
    • (2000) Expert Opin. Investig. Drugs , vol.9 , Issue.8 , pp. 1871-1875
    • ARGYROPOULOS, S.V.1    NUTT, D.J.2
  • 67
    • 1642488331 scopus 로고    scopus 로고
    • Substance P in the medial amygdala: Emotional stress-sensitive release and modulation of anxiety-related behavior in rats
    • EBNER K, RUPNIAK NM, SARIA A, SINGEWALD N: Substance P in the medial amygdala: emotional stress-sensitive release and modulation of anxiety-related behavior in rats. Proc. Natl. Acad. Sci. USA (2004) 101(12):4280-4285.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.12 , pp. 4280-4285
    • EBNER, K.1    RUPNIAK, N.M.2    SARIA, A.3    SINGEWALD, N.4
  • 68
    • 0027466839 scopus 로고
    • Distribution of the substance P receptor (NK-1 receptor) in the central nervous system
    • MAENO H, KIYAMA H, TOHYAMA M: Distribution of the substance P receptor (NK-1 receptor) in the central nervous system. Brain Res. Mol. Brain Res. (1993) 18(1-2):43-58.
    • (1993) Brain Res. Mol. Brain Res , vol.18 , Issue.1-2 , pp. 43-58
    • MAENO, H.1    KIYAMA, H.2    TOHYAMA, M.3
  • 70
    • 2642547366 scopus 로고    scopus 로고
    • Antidepressant properties of substance P antagonists: Relationship to monoaminergic mechanisms?
    • ADELL A: Antidepressant properties of substance P antagonists: relationship to monoaminergic mechanisms? Curr. Drug Targets CNS Neurol. Disord. (2004) 3(2):113-121.
    • (2004) Curr. Drug Targets CNS Neurol. Disord , vol.3 , Issue.2 , pp. 113-121
    • ADELL, A.1
  • 71
    • 17644433355 scopus 로고    scopus 로고
    • Serotonin and substance P co-exist in dorsal raphe neurons of the human brain
    • SERGEYEV V, HOKFELT T, HURD Y: Serotonin and substance P co-exist in dorsal raphe neurons of the human brain. Neuroreport (1999) 10(18):3967-3970.
    • (1999) Neuroreport , vol.10 , Issue.18 , pp. 3967-3970
    • SERGEYEV, V.1    HOKFELT, T.2    HURD, Y.3
  • 73
    • 0030937131 scopus 로고    scopus 로고
    • Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress
    • CULMAN J, KLEE S, OHLENDORF C, UNGER T: Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioral responses to stress. J. Pharmacol. Exp. Ther. (1997) 280(1):238-246.
    • (1997) J. Pharmacol. Exp. Ther , vol.280 , Issue.1 , pp. 238-246
    • CULMAN, J.1    KLEE, S.2    OHLENDORF, C.3    UNGER, T.4
  • 75
    • 18844402614 scopus 로고    scopus 로고
    • 1 receptor have a role in depression and anxiety?
    • 1 receptor have a role in depression and anxiety? Curr. Pharm. Des. (2005) 11(12):1529-1547.
    • (2005) Curr. Pharm. Des , vol.11 , Issue.12 , pp. 1529-1547
    • MCLEAN, S.1
  • 76
    • 3042611638 scopus 로고    scopus 로고
    • Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: Relevance to the antidepressant/anxiolytic response
    • BLIER P, GOBBI G, HADDJERI N et al.: Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response. J. Psychiatry Neurosci. (2004) 29(3):208-218.
    • (2004) J. Psychiatry Neurosci , vol.29 , Issue.3 , pp. 208-218
    • BLIER, P.1    GOBBI, G.2    HADDJERI, N.3
  • 78
    • 0036760233 scopus 로고    scopus 로고
    • Substance P (neurokinin 1) receptor antagonists enhance dorsal raphe neuronal activity
    • CONLEY RK, CUMBERBATCH MJ, MASON GS et al.: Substance P (neurokinin 1) receptor antagonists enhance dorsal raphe neuronal activity. J. Neurosci. (2002) 22(17):7730-7736.
    • (2002) J. Neurosci , vol.22 , Issue.17 , pp. 7730-7736
    • CONLEY, R.K.1    CUMBERBATCH, M.J.2    MASON, G.S.3
  • 79
    • 0035887916 scopus 로고    scopus 로고
    • 1A ]autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensidzation
    • 1A ]autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensidzation. J. Neurosci. (2001) 21(20):8188-8197.
    • (2001) J. Neurosci , vol.21 , Issue.20 , pp. 8188-8197
    • FROGER, N.1    GARDIER, A.M.2    MORATALLA, R.3
  • 80
    • 0035422889 scopus 로고    scopus 로고
    • Sustained blockade of neurokinin-1 receptors enhances serotonin neuroutransmission
    • HADDJERI N, BLIER P: Sustained blockade of neurokinin-1 receptors enhances serotonin neuroutransmission. Biol. Psychiatry (2001) 50(3):191-199.
    • (2001) Biol. Psychiatry , vol.50 , Issue.3 , pp. 191-199
    • HADDJERI, N.1    BLIER, P.2
  • 81
    • 0035852719 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and, Increases serotonergic function
    • SANTARELLI L, GOBBI G, DEBS PC et al.: Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and, Increases serotonergic function. Proc. Natl. Acad. Sci. USA (2001) 98(4):1912-1917.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.4 , pp. 1912-1917
    • SANTARELLI, L.1    GOBBI, G.2    DEBS, P.C.3
  • 82
    • 33644865629 scopus 로고    scopus 로고
    • Microdialysis approach to study serotonin outflow in mice following selective serotonin reuptake inhibitors and substance P (neurokinin 1) receptor antagonist administration: A review
    • GUIARD BP, LANFUMEY L, GARDIER AM: Microdialysis approach to study serotonin outflow in mice following selective serotonin reuptake inhibitors and substance P (neurokinin 1) receptor antagonist administration: a review. Curr. Drug Targets (2006) 7(2):187-201.
    • (2006) Curr. Drug Targets , vol.7 , Issue.2 , pp. 187-201
    • GUIARD, B.P.1    LANFUMEY, L.2    GARDIER, A.M.3
  • 83
    • 1842562860 scopus 로고    scopus 로고
    • Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: An in vivo microdialysis study in mice
    • GULARD BP, PRZYBYLSKI C, GUILLOUX JP et al.: Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. J. Neurochem. (2004) 89(1):54-63.
    • (2004) J. Neurochem , vol.89 , Issue.1 , pp. 54-63
    • GULARD, B.P.1    PRZYBYLSKI, C.2    GUILLOUX, J.P.3
  • 85
    • 18244364895 scopus 로고    scopus 로고
    • 1 antagonists-serotonin reuptake inhibitors: Synthesis and SAR of a new class of potential antidepressants
    • 1 antagonists-serotonin reuptake inhibitors: synthesis and SAR of a new class of potential antidepressants. Bioorg. Med. Chem. Lett. (2002) 12(2):261-264.
    • (2002) Bioorg. Med. Chem. Lett , vol.12 , Issue.2 , pp. 261-264
    • RYCKMANS, T.1    BALANCON, L.2    BERTON, O.3
  • 86
    • 0037020770 scopus 로고    scopus 로고
    • 1 antagonists - serotonin reuptake inhibitors as potential antidepressants. Part 2: SAR and activity of benzyloxyphenethyl piperazine derivatives
    • 1 antagonists - serotonin reuptake inhibitors as potential antidepressants. Part 2: SAR and activity of benzyloxyphenethyl piperazine derivatives. Bioorg. Med. Chem. Lett. (2002) 12(21):3195-3198.
    • (2002) Bioorg. Med. Chem. Lett , vol.12 , Issue.21 , pp. 3195-3198
    • RYCKMANS, T.1    BERTON, O.2    GRIMEE, R.3
  • 87
    • 30344448578 scopus 로고    scopus 로고
    • 1B receptor function by p11 in depression-like states
    • 1B receptor function by p11 in depression-like states. Science (2006) 311(5757):77-80.
    • (2006) Science , vol.311 , Issue.5757 , pp. 77-80
    • SVENNINGSSON, P.1    CHERGUI, K.2    RACHLEFF, I.3
  • 88
    • 33846968447 scopus 로고    scopus 로고
    • p11(S100A10) - an inducible adaptor protein that modulates neuronal functions
    • SVENNINGSSON P, GREENGARD P: p11(S100A10) - an inducible adaptor protein that modulates neuronal functions. Curr. Opin. Pharmacol. (2007) 7(1):27-32.
    • (2007) Curr. Opin. Pharmacol , vol.7 , Issue.1 , pp. 27-32
    • SVENNINGSSON, P.1    GREENGARD, P.2
  • 89
    • 16344366522 scopus 로고    scopus 로고
    • Positron emission tomography and single-photon emission computed tomography in central nervous system drug development
    • BROOKS DJ: Positron emission tomography and single-photon emission computed tomography in central nervous system drug development. NeuroRx (2005) 2(2):226-236.
    • (2005) NeuroRx , vol.2 , Issue.2 , pp. 226-236
    • BROOKS, D.J.1
  • 90
    • 33745050401 scopus 로고    scopus 로고
    • Using positron emission tomography to facilitate CNS drug development
    • LEE CM, FARDE L: Using positron emission tomography to facilitate CNS drug development. Trends Pharmacol. Sci. (2006) 27(6):310-316.
    • (2006) Trends Pharmacol. Sci , vol.27 , Issue.6 , pp. 310-316
    • LEE, C.M.1    FARDE, L.2
  • 91
    • 0036895218 scopus 로고    scopus 로고
    • The role of in vivo molecular imaging with PET and SPECT in the elucidation of psychiatric drug action and new drug development
    • TALBOT PS, LARUELLE M: The role of in vivo molecular imaging with PET and SPECT in the elucidation of psychiatric drug action and new drug development. Eur. Neuropsychopharmacol. (2002) 12(6):503-511.
    • (2002) Eur. Neuropsychopharmacol , vol.12 , Issue.6 , pp. 503-511
    • TALBOT, P.S.1    LARUELLE, M.2
  • 92
    • 27744561925 scopus 로고    scopus 로고
    • Positron ermission tomography: Applications in drug discovery and drug development
    • WANG J, MAURER L: Positron ermission tomography: applications in drug discovery and drug development. Curr. Top Med. Chem. (2005) 5(11):1053-1075.
    • (2005) Curr. Top Med. Chem , vol.5 , Issue.11 , pp. 1053-1075
    • WANG, J.1    MAURER, L.2
  • 94
    • 0036328183 scopus 로고    scopus 로고
    • Drug distribution in man: A positron emission tomography study after oral administration of the labelled neuroprorective drug vinpocetine
    • GULYAS B, HALLDIN C, SOVAGO J et al.: Drug distribution in man: a positron emission tomography study after oral administration of the labelled neuroprorective drug vinpocetine. Eur. J. Nucl. Med. Mol. Imaging (2002) 29(8):1031-1038.
    • (2002) Eur. J. Nucl. Med. Mol. Imaging , vol.29 , Issue.8 , pp. 1031-1038
    • GULYAS, B.1    HALLDIN, C.2    SOVAGO, J.3
  • 96
    • 10644257674 scopus 로고    scopus 로고
    • 11C]AFE is a selective serotonin transporter ligand with fast brain uptake kinetics
    • 11C]AFE is a selective serotonin transporter ligand with fast brain uptake kinetics. Nucl. Med. Biol. (2004) 31(8):983-994.
    • (2004) Nucl. Med. Biol , vol.31 , Issue.8 , pp. 983-994
    • ZHU, Z.1    GUO, N.2    NARENDRAN, R.3
  • 101
    • 0037383195 scopus 로고    scopus 로고
    • High levels of serotonin transporter occupancy with low-dose clomipramine in comparative occupancy study with fluvoxamine using positron emission tomography
    • SUHARA T, TAKANO A, SUDO Y et al.: High levels of serotonin transporter occupancy with low-dose clomipramine in comparative occupancy study with fluvoxamine using positron emission tomography. Arch. Gen. Psychiatry (2003) 60(4):386-391.
    • (2003) Arch. Gen. Psychiatry , vol.60 , Issue.4 , pp. 386-391
    • SUHARA, T.1    TAKANO, A.2    SUDO, Y.3
  • 102
    • 33645103129 scopus 로고    scopus 로고
    • A dose-finding study of duloxetine based on serotonin transporter occupancy
    • TAKANO A, SUZUKI K, KOSAKA J et al.: A dose-finding study of duloxetine based on serotonin transporter occupancy. Psychopharmacology (Berl.) (2006) 185(3):395-399.
    • (2006) Psychopharmacology (Berl.) , vol.185 , Issue.3 , pp. 395-399
    • TAKANO, A.1    SUZUKI, K.2    KOSAKA, J.3
  • 103
    • 27144442780 scopus 로고    scopus 로고
    • New-generation radiotracers for nAChR and NET
    • DING YS, FOWLER J: New-generation radiotracers for nAChR and NET. Nucl. Med. Biol. (2005) 32(7):707-718.
    • (2005) Nucl. Med. Biol , vol.32 , Issue.7 , pp. 707-718
    • DING, Y.S.1    FOWLER, J.2
  • 105
    • 0036452132 scopus 로고    scopus 로고
    • 1) in the living human brain using positron emission tomography
    • 1) in the living human brain using positron emission tomography. J. Clin. Psychiatry (2002) 63(Suppl. 11):18-24.
    • (2002) J. Clin. Psychiatry , vol.63 , Issue.SUPPL. 11 , pp. 18-24
    • HARGREAVES, R.1
  • 106
    • 2342483811 scopus 로고    scopus 로고
    • Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant
    • BERGSTROM M, HARGREAVES RJ, BURNS HD et al.: Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant. Biol. Psychiatry (2004) 55(10):1007-1012.
    • (2004) Biol. Psychiatry , vol.55 , Issue.10 , pp. 1007-1012
    • BERGSTROM, M.1    HARGREAVES, R.J.2    BURNS, H.D.3


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