SB-224289 - A novel selective (human) 5-HT(1B) receptor antagonist with negative intrinsic activity

British Journal of Pharmacology

Volumn 125, Issue 1, 1998, Pages 202-208

  Selkirk, J V ^a   Scott, C ^a   Ho, M ^a   Burton, M J ^a   Watson, J ^a   Gaster, L M ^a   Collin, L ^a   Jones, B J ^a   Middlemiss, D N ^a   Price, G W ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

5 HT; 5 HT(1B) autoreceptor; Inverse agonist; SB 224289

Indexed keywords

2,3,6,7 TETRAHYDRO 1' METHYL 5 [2' METHYL 4'[(5 METHYL 1,2,4 OXADIAZOL 3 YL)BIPHENYL 4 YL]CARBONYL]FURO[2,3 F]INDOLE 3 SPIRO 4' PIPERIDINE OXALATE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); METITEPINE; RADIOLIGAND; RECOMBINANT PROTEIN; SEROTONIN 1B ANTAGONIST; SEROTONIN 1B RECEPTOR; SEROTONIN 1D RECEPTOR; SULFUR 35; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; CHO CELL; COMPETITIVE INHIBITION; ELECTROSTIMULATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; SEROTONIN RELEASE;

ANIMALS; CHO CELLS; CRICETINAE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HELA CELLS; HUMANS; PIPERIDONES; RADIOLIGAND ASSAY; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEROTONIN; SEROTONIN ANTAGONISTS; SPIRO COMPOUNDS; SULFUR RADIOISOTOPES;

EID: 7344239900     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702059     Document Type: Article

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